Publications by authors named "Nazar Mashtalir"

28Publications

BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms.

Am J Hum Genet 2020 12 23;107(6):1096-1112. Epub 2020 Nov 23.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA; Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA; Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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December 2020

A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms.

Cell 2020 Oct 13;183(3):802-817.e24. Epub 2020 Oct 13.

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address:

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October 2020

Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes.

Cell 2018 11 18;175(5):1272-1288.e20. Epub 2018 Oct 18.

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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November 2018

Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens.

Cell Syst 2018 05 16;6(5):555-568.e7. Epub 2018 May 16.

Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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May 2018

The LMO2 oncogene regulates DNA replication in hematopoietic cells.

Proc Natl Acad Sci U S A 2016 Feb 13;113(5):1393-8. Epub 2016 Jan 13.

Institute of Research in Immunology and Cancer, University of Montreal, Montreal, QC, Canada H3C 3J7; Molecular Biology Program, University of Montreal, Montreal, QC, Canada H1T 2M4; Departments of Pharmacology and Biochemistry, University of Montreal, Montreal, QC, Canada H3T 1J2

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February 2016

The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.

J Biol Chem 2015 Nov 28;290(48):28643-63. Epub 2015 Sep 28.

From the Maisonneuve-Rosemont Hospital Research Center and Department of Medicine, University of Montréal, Montréal, Québec H3C 3J7, Canada and

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November 2015

Undetectable histone O-GlcNAcylation in mammalian cells.

Epigenetics 2015 ;10(8):677-91

a Maisonneuve-Rosemont Hospital Research Center and Department of Medicine; University of Montréal ; Montréal, Québec , Canada.

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May 2016

Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O.

Mol Cell 2014 May 3;54(3):392-406. Epub 2014 Apr 3.

Maisonneuve-Rosemont Hospital Research Center, Department of Medicine, University of Montréal, Montréal, QC H1T 2M4, Canada. Electronic address:

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May 2014

Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells.

Mol Cell Biol 2013 Aug 3;33(16):3064-76. Epub 2013 Jun 3.

Maisonneuve-Rosemont Hospital Research Center, Maisonneuve-Rosemont Hospital, and Department of Medicine, University of Montreal, Montreal, Quebec, Canada.

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August 2013

E4orf1: a novel ligand that improves glucose disposal in cell culture.

PLoS One 2011 23;6(8):e23394. Epub 2011 Aug 23.

Infections and Obesity Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, United States of America.

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January 2012

Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway.

Proc Natl Acad Sci U S A 2011 Feb 1;108(7):2747-52. Epub 2011 Feb 1.

Maisonneuve-Rosemont Hospital Research Center, Department of Medicine, University of Montréal, Montréal, QC, Canada H1T 2M4.

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February 2011

The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.

Mol Cell Biol 2010 Nov 30;30(21):5071-85. Epub 2010 Aug 30.

University of Montréal, Maisonneuve-Rosemont Hospital Research Center, Department of Medicine, Montréal, Québec, Canada.

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November 2010