Nathaniel R Landau

Nathaniel R Landau

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Nathaniel R Landau

Nathaniel R Landau

Publications by authors named "Nathaniel R Landau"

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Lentiviral Vector-Based Dendritic Cell Vaccine Suppresses HIV Replication in Humanized Mice.

Mol Ther 2019 05 15;27(5):960-973. Epub 2019 Mar 15.

Department of Microbiology, NYU Langone Medical Center, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2019.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520467PMC
May 2019

Toll-like receptor agonist R848 blocks Zika virus replication by inducing the antiviral protein viperin.

Virology 2018 09 20;522:199-208. Epub 2018 Jul 20.

Department of Microbiology, NYU School of Medicine, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2018.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130814PMC
September 2018

DNA damage induces a SAMHD1-mediated block to the infection of macrophages by HIV-1.

Sci Rep 2018 03 7;8(1):4153. Epub 2018 Mar 7.

Department of Microbiology, NYU School of Medicine, Smilow Research Building, Rm. 1003, 550 First Avenue, New York, 10016, USA.

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http://www.nature.com/articles/s41598-018-22432-4
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http://dx.doi.org/10.1038/s41598-018-22432-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841438PMC
March 2018

A Highly Active Isoform of Lentivirus Restriction Factor SAMHD1 in Mouse.

J Biol Chem 2017 01 5;292(3):1068-1080. Epub 2016 Dec 5.

From the Department of Microbiology, New York School of Medicine, New York, New York 10016,

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http://dx.doi.org/10.1074/jbc.M116.743740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247641PMC
January 2017

TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes.

Retrovirology 2016 Dec 1;13(1):83. Epub 2016 Dec 1.

Department of Microbiology, NYU School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1186/s12977-016-0316-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131500PMC
December 2016

Intrinsic host restrictions to HIV-1 and mechanisms of viral escape.

Nat Immunol 2015 Jun;16(6):546-53

Department of Microbiology, NYU School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1038/ni.3156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908429PMC
June 2015

SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells.

PLoS One 2014 19;9(2):e89558. Epub 2014 Feb 19.

Department of Microbiology, NYU School of Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089558PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929709PMC
October 2014

SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors.

Antimicrob Agents Chemother 2014 Aug 27;58(8):4915-9. Epub 2014 May 27.

Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, Missouri, USA Department of Molecular Microbiology & Immunology, University of Missouri School of Medicine, Columbia, Missouri, USA Department of Biochemistry, University of Missouri, Columbia, Missouri, USA

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http://dx.doi.org/10.1128/AAC.02745-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136039PMC
August 2014

Interactions with DCAF1 and DDB1 in the CRL4 E3 ubiquitin ligase are required for Vpr-mediated G2 arrest.

Virol J 2014 Jun 9;11:108. Epub 2014 Jun 9.

Department of Microbiology, New York University School of Medicine, 522 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1186/1743-422X-11-108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058697PMC
June 2014

The innate immune response to HIV-1: to sense or not to sense.

DNA Cell Biol 2014 May 25;33(5):271-4. Epub 2014 Mar 25.

Department of Microbiology, NYU School of Medicine , New York, New York.

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http://dx.doi.org/10.1089/dna.2014.2378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010161PMC
May 2014

HIV type 1 infection of plasmacytoid and myeloid dendritic cells is restricted by high levels of SAMHD1 and cannot be counteracted by Vpx.

AIDS Res Hum Retroviruses 2014 Feb 4;30(2):195-203. Epub 2013 Sep 4.

1 Department of Microbiology, New York University School of Medicine , New York, New York.

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http://dx.doi.org/10.1089/AID.2013.0119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910455PMC
February 2014

Inhibition of CUL4A Neddylation causes a reversible block to SAMHD1-mediated restriction of HIV-1.

J Virol 2013 Nov 28;87(21):11741-50. Epub 2013 Aug 28.

Microbiology Department, New York University School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1128/JVI.02002-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807335PMC
November 2013

Restriction of diverse retroviruses by SAMHD1.

Retrovirology 2013 Mar 5;10:26. Epub 2013 Mar 5.

Microbiology Department, New York University School of Medicine, New York, USA.

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http://dx.doi.org/10.1186/1742-4690-10-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605129PMC
March 2013

CCR5 is a receptor for Staphylococcus aureus leukotoxin ED.

Nature 2013 Jan 12;493(7430):51-5. Epub 2012 Dec 12.

Department of Microbiology, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/nature11724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536884PMC
January 2013

The cargo-binding domain of transportin 3 is required for lentivirus nuclear import.

J Virol 2011 Dec 5;85(24):12950-61. Epub 2011 Oct 5.

Department of Microbiology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1128/JVI.05384-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233122PMC
December 2011

Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells.

J Virol 2011 Jul 20;85(13):6263-74. Epub 2011 Apr 20.

Department of Microbiology, New York University School of Medicine, 522 First Ave., New York, NY 10016, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.00346-11
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http://dx.doi.org/10.1128/JVI.00346-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126535PMC
July 2011

Evidence for an activation domain at the amino terminus of simian immunodeficiency virus Vpx.

J Virol 2010 Feb 18;84(3):1387-96. Epub 2009 Nov 18.

New York University School of Medicine, Microbiology Department, 522 First Ave., New York, NY 10016, USA.

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http://dx.doi.org/10.1128/JVI.01437-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812310PMC
February 2010

Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent.

Virology 2009 May 21;387(2):313-21. Epub 2009 Mar 21.

Department of Microbiology, New York University School of Medicine, New York, 10016, USA.

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http://dx.doi.org/10.1016/j.virol.2009.02.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708462PMC
May 2009

Guidelines for naming nonprimate APOBEC3 genes and proteins.

J Virol 2009 Jan 5;83(2):494-7. Epub 2008 Nov 5.

Department of Biochemistry, Molecular Biology and Biophysics, Institute for Molecular Virology, Beckman Center for Genome Engineering, Comparative and Molecular Biology Graduate Program, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1128/JVI.01976-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612408PMC
January 2009

Analysis of Vif-induced APOBEC3G degradation using an alpha-complementation assay.

Virology 2007 Mar 17;359(1):162-9. Epub 2006 Oct 17.

Infectious Disease Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037-1099, USA.

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http://dx.doi.org/10.1016/j.virol.2006.09.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708489PMC
March 2007

HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1.

Proc Natl Acad Sci U S A 2007 Mar 28;104(10):4130-5. Epub 2007 Feb 28.

Infectious Disease Laboratory, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037-1099, USA.

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http://dx.doi.org/10.1073/pnas.0610167104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820720PMC
March 2007

Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains.

J Biol Chem 2006 Dec 4;281(48):36624-31. Epub 2006 Oct 4.

Infectious Disease Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1074/jbc.M604980200DOI Listing
December 2006

Mutational alteration of human immunodeficiency virus type 1 Vif allows for functional interaction with nonhuman primate APOBEC3G.

J Virol 2006 Jun;80(12):5984-91

Infectious Disease Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1128/JVI.00388-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472613PMC
June 2006

APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons.

Curr Biol 2006 Mar;16(5):480-5

Infectious Disease Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1016/j.cub.2006.01.031DOI Listing
March 2006

Human immunodeficiency virus type 1 Vpr induces the degradation of the UNG and SMUG uracil-DNA glycosylases.

J Virol 2005 Sep;79(17):10978-87

Infectious Disease Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1128/JVI.79.17.10978-10987.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1193627PMC
September 2005

Complementary function of the two catalytic domains of APOBEC3G.

Virology 2005 Mar;333(2):374-86

Infectious Disease Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.virol.2005.01.011DOI Listing
March 2005

APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication.

J Biol Chem 2004 Dec 4;279(51):53379-86. Epub 2004 Oct 4.

Infectious Disease Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1074/jbc.M408802200DOI Listing
December 2004

Recent insights into HIV-1 Vif.

Curr Opin Immunol 2004 Aug;16(4):477-82

The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.coi.2004.05.006DOI Listing
August 2004

New insights into the role of Vif in HIV-1 replication.

AIDS Rev 2004 Jan-Mar;6(1):34-9

Infectious Disease Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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July 2004

Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome.

Nat Struct Mol Biol 2004 May 18;11(5):435-42. Epub 2004 Apr 18.

Infectious Disease Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nsmb758DOI Listing
May 2004

A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif).

Proc Natl Acad Sci U S A 2004 Mar 20;101(11):3927-32. Epub 2004 Feb 20.

Infectious Disease Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0307132101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC374346PMC
March 2004

Alpha-complementation assay for HIV envelope glycoprotein-mediated fusion.

Virology 2004 Feb;319(2):343-52

Infectious Disease Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.virol.2003.11.012DOI Listing
February 2004

Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii.

Blood 2003 Nov 10;102(9):3280-6. Epub 2003 Jul 10.

Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bldg 29A, Rm 1A21, 8800 Rockville Pike, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1182/blood-2003-04-1096DOI Listing
November 2003

Production and use of HIV-1 luciferase reporter viruses.

Curr Protoc Pharmacol 2003 Nov;Chapter 12:Unit12.5

The Salk Institute for Biological Studies, La Jolla, California, USA

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http://dx.doi.org/10.1002/0471141755.ph1205s22DOI Listing
November 2003

The theta-defensin, retrocyclin, inhibits HIV-1 entry.

AIDS Res Hum Retroviruses 2003 Oct;19(10):875-81

Infectious Disease Laboratory, Salk Institute for Biological Studies, San Diego, CA 92037, USA.

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http://dx.doi.org/10.1089/088922203322493049DOI Listing
October 2003

Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif.

Cell 2003 Jul;114(1):21-31

Infectious Disease Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/s0092-8674(03)00515-4DOI Listing
July 2003

Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells.

Proc Natl Acad Sci U S A 2003 Feb 23;100(3):1298-303. Epub 2003 Jan 23.

Laboratory of Genetics and Infectious Disease Laboratory, The Salk Institute, La Jolla, CA 92037-1099, USA.

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http://dx.doi.org/10.1073/pnas.0337541100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC298767PMC
February 2003

HIV-1 Vpr activates cell cycle inhibitor p21/Waf1/Cip1: a potential mechanism of G2/M cell cycle arrest.

Virology 2003 Jan;305(2):371-7

Henry M. Jackson Foundation for the Advancement of Military Medicine, Rockville 20850, USA.

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http://dx.doi.org/10.1006/viro.2002.1777DOI Listing
January 2003

A dominant block to HIV-1 replication at reverse transcription in simian cells.

Proc Natl Acad Sci U S A 2002 Oct 4;99(21):13843-8. Epub 2002 Oct 4.

The Salk Institute for Biological Studies, Infectious Disease Laboratory, 10010 North Torrey Pines Road, La Jolla, CA 92037.

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http://dx.doi.org/10.1073/pnas.212400099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC129785PMC
October 2002

Vpr- and Nef-dependent induction of RANTES/CCL5 in microglial cells.

Virology 2002 Sep;301(2):342-53

Department of Pathology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1006/viro.2002.1613DOI Listing
September 2002

A cellular cofactor in HIV-1 assembly: INI1 is also an "outtie".

Trends Pharmacol Sci 2002 Jun;23(6):252-3

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http://dx.doi.org/10.1016/s0165-6147(02)02021-7DOI Listing
June 2002

Association of chemokine-mediated block to HIV entry with coreceptor internalization.

J Biol Chem 2002 May 8;277(19):17291-9. Epub 2002 Jan 8.

Salk Institute for Biological Studies, Infectious Disease Laboratory, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1074/jbc.M108232200DOI Listing
May 2002