Nathaniel Alpert

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Nathaniel Alpert

Publications by authors named "Nathaniel Alpert"

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52Publications

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Quantitative in vivo mapping of myocardial mitochondrial membrane potential.

PLoS One 2018 16;13(1):e0190968. Epub 2018 Jan 16.

Gordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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February 2018

Frontostriatal and Dopamine Markers of Individual Differences in Reinforcement Learning: A Multi-modal Investigation.

Cereb Cortex 2017 Oct 31:1-10. Epub 2017 Oct 31.

Department of Psychiatry, Harvard Medical School, and Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA 02478, USA.

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October 2017

Rapid computation of single PET scan rest-stress myocardial blood flow parametric images by table look up.

Med Phys 2017 Sep 18;44(9):4643-4651. Epub 2017 Jul 18.

Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114-1107, USA.

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September 2017

Single-scan rest/stress imaging: validation in a porcine model with F-Flurpiridaz.

Eur J Nucl Med Mol Imaging 2017 Aug 1;44(9):1538-1546. Epub 2017 Apr 1.

Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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August 2017

Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR.

Phys Med Biol 2017 01 20;62(2):326-343. Epub 2016 Dec 20.

Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA. Department of Radiology, Harvard Medical School, Boston, MA 02115, USA.

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January 2017

Validation of Bayesian analysis of compartmental kinetic models in medical imaging.

Phys Med 2016 Oct 28;32(10):1252-1258. Epub 2016 Sep 28.

Massachusetts General Hospital and Harvard Medical School, Radiology Department, 55 Fruit Street, Boston, MA 02114, USA.

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October 2016

National Electrical Manufacturers Association and Clinical Evaluation of a Novel Brain PET/CT Scanner.

J Nucl Med 2016 Apr 23;57(4):646-52. Epub 2015 Dec 23.

The Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts

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April 2016

Mapping (15)O production rate for proton therapy verification.

Int J Radiat Oncol Biol Phys 2015 Jun 25;92(2):453-9. Epub 2015 Mar 25.

Center for Advanced Radiological Sciences, Nuclear Medicine and Molecular Imaging, Radiology Department, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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June 2015

Dual-tracer PET using generalized factor analysis of dynamic sequences.

Mol Imaging Biol 2013 Dec;15(6):666-74

Center for Advanced Medical Imaging Sciences NMMI, Radiology Department, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA,

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December 2013

Direct reconstruction of cardiac PET kinetic parametric images using a preconditioned conjugate gradient approach.

Med Phys 2013 Oct;40(10):102501

Center for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, Boston, Massachusetts 02114 and Department of Radiology, Harvard Medical School, Boston, Massachusetts 02114.

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October 2013

Bias atlases for segmentation-based PET attenuation correction using PET-CT and MR.

IEEE Trans Nucl Sci 2013 Oct;60(5):3373-3382

Center for Advanced Radiological Sciences, Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, Boston; Harvard Medical School, Boston.

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October 2013

A receptor-based model for dopamine-induced fMRI signal.

Neuroimage 2013 Jul 1;75:46-57. Epub 2013 Mar 1.

Division of Nuclear Medicine, Massachusetts General Hospital, Boston, MA, USA.

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July 2013

Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI.

Proc Natl Acad Sci U S A 2013 Jul 30;110(27):11169-74. Epub 2013 May 30.

Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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July 2013

Single-scan rest∕stress imaging (18)F-labeled flow tracers.

Med Phys 2012 Nov;39(11):6609-20

Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.

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November 2012

MRI-based nonrigid motion correction in simultaneous PET/MRI.

J Nucl Med 2012 Aug 28;53(8):1284-91. Epub 2012 Jun 28.

Center for Advanced Radiological Sciences, Nuclear Medicine and Molecular Imaging, Radiology Department, Massachusetts General Hospital, Boston, MA 02114, USA.

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August 2012

Parametric imaging with Bayesian priors: a validation study with (11)C-Altropane PET.

Neuroimage 2012 May 9;61(1):131-8. Epub 2012 Mar 9.

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.

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May 2012

Dopamine release during human emotional processing.

Neuroimage 2009 Oct 11;47(4):2041-5. Epub 2009 Jun 11.

Division of Nuclear Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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October 2009

A general method of Bayesian estimation for parametric imaging of the brain.

Neuroimage 2009 May 14;45(4):1183-9. Epub 2009 Jan 14.

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, 50 Fruit Street, Boston, MA 02114, USA.

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May 2009

Explicit motor memory activates the striatal dopamine system.

Neuroreport 2008 Mar;19(4):409-12

Division of Nuclear Medicine (White 427), Massachusetts General Hospital, Boston, MA 02114, USA.

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March 2008

Striatal dopamine release in sequential learning.

Neuroimage 2007 Nov 15;38(3):549-56. Epub 2007 Aug 15.

Division of Nuclear Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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November 2007

PET/CT imaging for treatment verification after proton therapy: a study with plastic phantoms and metallic implants.

Med Phys 2007 Feb;34(2):419-35

Department of Radiation Oncology, Massachusetts General Hospital, 30 Fruit Street, Boston, Massachusetts 02114, USA.

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February 2007

Optimization of dynamic measurement of receptor kinetics by wavelet denoising.

Neuroimage 2006 Apr 27;30(2):444-51. Epub 2005 Oct 27.

Division of Nuclear Medicine, Massachusetts General Hospital, 50 Fruit Street, Boston, MA 02129, USA.

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April 2006

A functional neuroimaging investigation of deep brain stimulation in patients with obsessive-compulsive disorder.

J Neurosurg 2006 Apr;104(4):558-65

Division of Psychiatric Neuroscience Research and Neurotherapeutics, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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April 2006

Accelerated triacylglycerol turnover kinetics in hearts of diabetic rats include evidence for compartmented lipid storage.

Am J Physiol Endocrinol Metab 2006 Mar 18;290(3):E448-55. Epub 2005 Oct 18.

Program in Integrative Cardiac Metabolism, University of Illinois at Chicago, Chicago, IL 60612, USA.

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March 2006

Effects of sildenafil on myocardial blood flow in humans with ischemic heart disease.

Coron Artery Dis 2005 Nov;16(7):443-9

Department of Medicine (Cardiac Unit), Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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November 2005

High-dose folic acid acutely improves coronary vasodilator function in patients with coronary artery disease.

J Am Coll Cardiol 2005 May 26;45(10):1580-4. Epub 2005 Apr 26.

Department of Medicine (Cardiac Unit), Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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May 2005

Two types of image generation: evidence from PET.

Cogn Affect Behav Neurosci 2005 Mar;5(1):41-53

Department of Psychology, Harvard University, 832 William James Hall, 33 Kirkland Street, Cambridge, MA 02138, USA.

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March 2005

Priming of new associations: a PET study.

Neuroreport 2003 Dec;14(18):2475-9

Department of Psychology, Harvard University, William James Hall, Rm 875, 33, Kirkland Street, Cambridge, MA 02138, USA.

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December 2003

Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for treatment of major depression.

J Neurosurg 2003 Dec;99(6):1010-7

Department of Psychiatry, Radiology, Neurosurgery, and Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, USA.

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December 2003

Improved radiologic staging of lung cancer with 2-[18F]-fluoro-2-deoxy-D-glucose-positron emission tomography and computed tomography registration.

J Comput Assist Tomogr 2003 Jul-Aug;27(4):479-84

Department of Radiology, FND 202, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.

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August 2003

Striatal dopamine release during unrewarded motor task in human volunteers.

Neuroreport 2003 Aug;14(11):1421-4

Division of Nuclear Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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August 2003

Implicit transfer of motor strategies in mental rotation.

Brain Cogn 2003 Jul;52(2):135-43

Department of Psychology, Smith College, Northampton, MA 01063, USA.

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July 2003

A novel method for noninvasive detection of neuromodulatory changes in specific neurotransmitter systems.

Neuroimage 2003 Jul;19(3):1049-60

Division of Nuclear Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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July 2003

Effects of age and speed of processing on rCBF correlates of syntactic processing in sentence comprehension.

Hum Brain Mapp 2003 Jun;19(2):112-31

Neuropsychology Laboratory, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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June 2003

Coregistration of head CT comparison studies: assessment of clinical utility.

Acad Radiol 2003 Mar;10(3):242-8

Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA.

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March 2003

Impaired hippocampal recruitment during normal modulation of memory performance in schizophrenia.

Biol Psychiatry 2003 Jan;53(1):48-55

Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02129, USA.

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January 2003

Predictors of fluvoxamine response in contamination-related obsessive compulsive disorder: a PET symptom provocation study.

Neuropsychopharmacology 2002 Nov;27(5):782-91

Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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November 2002

Pharmacokinetic imaging: a noninvasive method for determining drug distribution and action.

Clin Pharmacokinet 2002 ;41(8):581-602

Department of Radiology, Division of Nuclear Medicine, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA.

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September 2002

Hippocampal and brain stem activation during word retrieval after repeated and semantic encoding.

Cereb Cortex 2002 Sep;12(9):900-7

Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Cambridge, MA, USA.

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September 2002

Homocysteine impairs coronary microvascular dilator function in humans.

J Am Coll Cardiol 2002 Sep;40(6):1051-58

Departments of Medicine (Cardiac Unit), Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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September 2002

Retrieval of relational information: a role for the left inferior prefrontal cortex.

Neuroimage 2002 Sep;17(1):393-400

Department of Psychology, Harvard University, Cambridge, MA 02138, USA.

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September 2002

Regional measurement of canine skeletal muscle blood flow by positron emission tomography with H2(15)O.

J Appl Physiol (1985) 2002 Apr;92(4):1709-16

Division of Nuclear Medicine, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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April 2002

Mapping of local renal blood flow with PET and H(2)(15)O.

J Nucl Med 2002 Apr;43(4):470-5

Division of Nuclear Medicine, Department of Radiology, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA.

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April 2002

Coupling of mitochondrial fatty acid uptake to oxidative flux in the intact heart.

Biophys J 2002 Jan;82(1 Pt 1):11-8

Program in Integrative Cardiac Metabolism, Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, Illinois 60612-7342, USA.

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January 2002

Pharmacokinetics of 18F-labeled trovafloxacin in normal and Escherichia coli-infected rats and rabbits studied with positron emission tomography.

Clin Microbiol Infect 1997 Feb;3(1):63-72

Division of Nuclear Medicine of the Department of Radiology, Massachusetts General Hospital, and the Department of Radiology, Harvard Medical School, Boston MA, USA.

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February 1997