Publications by authors named "Nathan Valle Soubihe"

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Development of a Multifunctional Needle for Percutaneous Heart Biopsy and Cell Therapy. A Technical Note.

Braz J Cardiovasc Surg 2016 Nov-Dec;31(6):465-467

Department of Surgery and Anatomy, Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, Brazil.

Validation of transendocardial injection as a method for delivering therapeutic agents to the diseased heart is increasing. Puncture heart biopsies should re-emerge as a possible alternative method to allow access to the myocardium and implantable biomaterial for cell therapy. Therefore, this work aims to present a percutaneous puncture device for biopsy and intramyocardial biomaterial injection, standardize the technique and attest to the safety of the method. The adaptation consists of creating myocardial microlesions that allow for better fixation of stem cells. The objective of this technical note covers only the development of the needle and the histological quality of the biopsies. It has not been used in humans yet.
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http://dx.doi.org/10.5935/1678-9741.20160092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407138PMC
November 2017