Dr. Nathan D Schilaty, DC, PhD - Mayo Clinic - Associate Consultant

Dr. Nathan D Schilaty

DC, PhD

Mayo Clinic

Associate Consultant

Rochester, Minnesota | United States

Main Specialties: Biology, Neuromuscular Medicine, Physical Medicine & Rehabilitation, Sports Medicine

Additional Specialties: Neuromechanics; Biomechanics; Neuroscience

ORCID logohttps://orcid.org/0000-0002-6038-7126


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Dr. Nathan D Schilaty, DC, PhD - Mayo Clinic - Associate Consultant

Dr. Nathan D Schilaty

DC, PhD

Introduction

Primary Affiliation: Mayo Clinic - Rochester, Minnesota , United States

Specialties:

Additional Specialties:

Research Interests:

Education

Jan 2018 - Mar 2019
Mayo Clinic Rochester
Postdoctoral Certificate - Clinical and Translational Science
Center for Clinical and Translational Science
Aug 2011 - Dec 2014
Brigham Young University
PhD - Neuroscience
Physiology & Developmental Biology
Dec 2014
Brigham Young University
PhD
Jan 2004 - Jan 2007
Parker University
DC - Doctorate of Chiropractic
Chiropractic Medicine
Jan 2007
Parker University
DC
Jan 2004 - Aug 2006
Parker University
BS - Health & Wellness
Jan 2004 - Aug 2005
Parker University
BS - Anatomy
Sep 1999 - Aug 2003
Salt Lake Community College
AS - Chemistry
Natural Sciences

Experience

Nov 2016 - Jul 2017
Mayo Clinic
Research Associate
Orthopedic Surgery
Jul 2015 - Nov 2016
Mayo Clinic
Research Fellow
Orthopedic Surgery
Dec 2014 - Jul 2015
Ohio State University
Postdoctoral Researcher
Sports Medicine
Aug 2011 - Dec 2014
Brigham Young University
Research Assistant
Psychology
Jan 2007 - Aug 2011
Front Range Community College
Adjunct Professor
Natural Applied and Environmental Sciences
Jul 2017
Mayo Clinic
Associate Consultant
Orthopedic Surgery / Physiology & Biomedical Engineering

Publications

14Publications

266Reads

-Profile Views

35PubMed Central Citations

Validation of Noncontact Anterior Cruciate Ligament Tears Produced by a Mechanical Impact Simulator Against the Clinical Presentation of Injury.

Am J Sports Med 2018 07 4;46(9):2113-2121. Epub 2018 Jun 4.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1177/0363546518776621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405414PMC
July 2018
12 Reads
1 Citation
4.362 Impact Factor

Effects of localized vibration on knee joint position sense in individuals with anterior cruciate ligament reconstruction.

Clin Biomech (Bristol, Avon) 2018 06 14;55:40-44. Epub 2018 Apr 14.

Biomechanics Laboratories, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, United States; Sports Medicine Center, Mayo Clinic, Rochester, MN, United States; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiomech.2018.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960437PMC
June 2018
33 Reads
1.880 Impact Factor

Analysis of Lower Extremity Proprioception for Anterior Cruciate Ligament Injury Prevention: Current Opinion.

Sports Med 2018 06;48(6):1303-1309

Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/s40279-018-0889-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949077PMC
June 2018
17 Reads
5.040 Impact Factor

Relative dearth of 'sex differences' research in sports medicine.

J Sci Med Sport 2018 May 3;21(5):440-441. Epub 2017 Nov 3.

Department of Orthopedic Surgery, Mayo Clinic, United States; Sports Medicine Center, Mayo Clinic, United States; Department of Physiology & Biomedical Engineering, Mayo Clinic, United States; Department of Physical Medicine & Rehabilitation, Mayo Clinic, United States; Department of Biomedical Engineering, The Ohio State University, United States.

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http://dx.doi.org/10.1016/j.jsams.2017.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927370PMC
May 2018
11 Reads

Sex-Based Differences of Medial Collateral Ligament and Anterior Cruciate Ligament Strains With Cadaveric Impact Simulations.

Orthop J Sports Med 2018 Apr 12;6(4):2325967118765215. Epub 2018 Apr 12.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1177/2325967118765215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900820PMC
April 2018
12 Reads

Ligament Strain Response Between Lower Extremity Contralateral Pairs During In Vitro Landing Simulation.

Orthop J Sports Med 2018 Apr 9;6(4):2325967118765978. Epub 2018 Apr 9.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1177/2325967118765978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894909PMC
April 2018
12 Reads

Sex-Based Differences in Knee Kinetics With Anterior Cruciate Ligament Strain on Cadaveric Impact Simulations.

Orthop J Sports Med 2018 Mar 15;6(3):2325967118761037. Epub 2018 Mar 15.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1177/2325967118761037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858624PMC
March 2018
23 Reads

Effect of sagittal plane mechanics on ACL strain during jump landing.

J Orthop Res 2017 06 31;35(6):1171-1172. Epub 2017 Jan 31.

Biomechanics Laboratories, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/jor.23523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929979PMC
June 2017
10 Reads
3 Citations
2.990 Impact Factor

Use of Objective Neurocognitive Measures to Assess the Psychological States that Influence Return to Sport Following Injury.

Sports Med 2016 Mar;46(3):299-303

Biomechanics Laboratories, Department of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s40279-015-0435-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769956PMC
March 2016
36 Reads
6 Citations
5.040 Impact Factor

Effects of the aqueous extract of Schizandra chinensis fruit on ethanol withdrawal-induced anxiety in rats.

Chin Med J (Engl) 2014 ;127(10):1935-40

Department of Pharmacology, Mudanjiang Medical University, Mudanjiang, Heilongjiang 157011, China. Email:

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April 2015
32 Reads
1 Citation
1.020 Impact Factor

Acute ethanol inhibits dopamine release in the nucleus accumbens via α6 nicotinic acetylcholine receptors.

J Pharmacol Exp Ther 2014 Jun 18;349(3):559-67. Epub 2014 Mar 18.

Department of Psychology and Center for Neuroscience, Brigham Young University, Provo, Utah (N.D.S., D.M.H., E.Y.J., R.J.F., S.C.S.); Vollum Institute, Oregon Health and Science University, Portland, Oregon (J.T.Y.); and Interdepartmental Program in Neuroscience, University of Utah, Salt Lake City, Utah (J.M.M.).

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http://dx.doi.org/10.1124/jpet.113.211490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170119PMC
June 2014
12 Reads
9 Citations
3.972 Impact Factor

Connexin-36 Knock-Out Mice have Increased Threshold for Kindled Seizures: Role of GABA Inhibition

Shin SI, Andersen DJ, Hansen DM, Yorgason JT, Schilaty ND, et al. (2013) Connexin-36 Knock-Out Mice have Increased Threshold for Kindled Seizures: Role of GABA Inhibition. Biochem Pharmacol (Los Angel) S1:006. doi: 10.4172/2167-0501.S1-006

Biochemistry & Pharmacology

Blockade of gap junctions (GJs) has been shown to reduce seizures in different epilepsy models. Gap junctionmediated, electrically-coupled neuronal networks have been implicated in neuronal synchronization, which is the hallmark of seizure activity. To further understand the role of GJs in seizures, in particular hippocampal seizures, we evaluated electrophysiological responses in the dentate gyrus subfield of the hippocampus, including GABA-mediated recurrent inhibition, seizuregenic stimulation, and seizure activity in response to perforant path kindling in Cx36 knockout (KO) mice compared to wild-type (WT) controls. In anesthetized mice, Cx36 KO mice were characterized by enhanced GABA-mediated recurrent inhibition. Stimulation of the perforant path at 10 Hz for 10 sec (i.e., 100 pulses) markedly enhanced population spike (PS) amplitudes and reduced paired-pulse GABA-mediated inhibition during the stimulation, induced an after discharge for approximately 10 sec at 7-10 sec into the stimulation, and suppressed PS amplitudes postictally for 5-10 min in both KO and WT mice. Repeated epochs of 10 Hz for 10 sec stimulation of the perforant path at 20 min intervals resulted in progressive and persistent disinhibition of paired-pulse responses in WT, but not KO mice. In freely-behaving seizure studies, stimulation of the perforant path (10 Hz for 10 sec) once/day resulted in progressive Stage I-IV seizures in both WT and KO mice. Once Stage IV was achieved, another Stage IV seizure could be elicited each day with the same behavioral response (i.e., Stage V). The threshold for kindled seizures was significantly greater in KO mice compared to WT controls for most stages of seizures. The Cx36 antagonist mefloquine (MFQ) and the typical anticonvulsant pentobarbital reduced Stage IV seizures in both WT and KO mice. Knock-out mice were more sensitive to the anti-epileptic effects of the typical anti-convulsant pentobarbital (20 mg/ kg). Taken together, these findings support the emerging view that reduction in GJ-mediated GABA electrical coupling reduces seizures, perhaps through enhancement of GABAergic feedback inhibition, which results from the uncoupling of the GABA recurrent interneurons from the resistive load that is inherent in their electrical connectivity.

http://omicsgroup.org/journals/connexin-knockout-mice-have-increased-threshold-for-kindled-seizures-role-of-gaba-inhibition-2167-0501.S1-006.php?aid=12446

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April 2013
17 Reads

Top co-authors

Timothy E Hewett
Timothy E Hewett

Mayo Clinic

10
Nathaniel A Bates
Nathaniel A Bates

Mayo Clinic

6
Aaron J Krych
Aaron J Krych

Mayo Clinic

4
Christopher V Nagelli
Christopher V Nagelli

Orthopedic Biomechanics Laboratories

3
Eun Young Jang
Eun Young Jang

College of Korean Medicine

3
Christopher Nagelli
Christopher Nagelli

Mayo Clinic

2
Ryan J Folsom
Ryan J Folsom

Center for Neuroscience

2
Takashi Nagai
Takashi Nagai

National Institute of Livestock and Grassland Science

2
Scott C Steffensen
Scott C Steffensen

Brigham Young University

2
David M Hedges
David M Hedges

Brigham Young University

2