Nathalie Scholler

Nathalie Scholler

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Nathalie Scholler

Nathalie Scholler

Publications by authors named "Nathalie Scholler"

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51Publications

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Selection of Antibody Fragments by Yeast Display.

Methods Mol Biol 2018 ;1827:211-233

Kite, a Gilead Company, Santa Monica, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-8648-4_12DOI Listing
April 2019

Generation of a Fully Human scFv that binds Tumor-Specific Glycoforms.

Sci Rep 2019 Mar 25;9(1):5101. Epub 2019 Mar 25.

University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology, Little Rock, AR, 72205, USA.

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http://www.nature.com/articles/s41598-019-41567-6
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http://dx.doi.org/10.1038/s41598-019-41567-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433917PMC
March 2019

Molecular Imaging of Mesothelin-Expressing Ovarian Cancer with a Human and Mouse Cross-Reactive Nanobody.

Mol Pharm 2018 04 28;15(4):1403-1411. Epub 2018 Feb 28.

Biosciences Division , SRI International , 333 Ravenswood Avenue , Menlo Park , California 94025 , United States.

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http://dx.doi.org/10.1021/acs.molpharmaceut.7b00789DOI Listing
April 2018

Tumor Regression and Delayed Onset Toxicity Following B7-H4 CAR T Cell Therapy.

Mol Ther 2016 Nov 21;24(11):1987-1999. Epub 2016 Jul 21.

Department of Pathology and Laboratory Medicine, Center for Cellular Immunotherapies, Philadelphia, Pennsylvania, USA; Department of Obstetrics and Gynecology, Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1038/mt.2016.149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154474PMC
November 2016

Isolation and Validation of Anti-B7-H4 scFvs from an Ovarian Cancer scFv Yeast-Display Library.

Methods Mol Biol 2015 ;1319:37-49

Department of Oncology, Ludwig Cancer Research Center, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/978-1-4939-2748-7_2DOI Listing
March 2016

ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells.

Blood 2014 Aug 1;124(7):1070-80. Epub 2014 Jul 1.

Abramson Cancer Center and the Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;

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http://dx.doi.org/10.1182/blood-2013-10-535245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133482PMC
August 2014

Immunocompetent mouse model of ovarian cancer for in vivo imaging.

Methods Mol Biol 2013 ;1049:425-33

Department of Obstetrics and Gynecology, Penn Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-1-62703-547-7_32DOI Listing
March 2014

Facile immunotargeting of nanoparticles against tumor antigens using site-specific biotinylated antibody fragments.

J Biomed Nanotechnol 2013 Oct;9(10):1686-97

Penn Ovarian Cancer Research Center, Department of Obstetrics and Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

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October 2013

Novel recombinant human b7-h4 antibodies overcome tumoral immune escape to potentiate T-cell antitumor responses.

Cancer Res 2013 Aug 30;73(15):4820-9. Epub 2013 May 30.

Department of Obstetrics and Gynecology, Ovarian Cancer Research Center, and Departments of Pathology and Laboratory Medicine and Hematology/Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732560PMC
August 2013

Blocking the B7-H4 pathway with novel recombinant antibodies enhances T cell-mediated antitumor responses.

Oncoimmunology 2013 Aug 31;2(8):e25913. Epub 2013 Jul 31.

Department of Oncology; Ludwig Cancer Research Center; University of Lausanne; Lausanne, Switzerland.

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http://dx.doi.org/10.4161/onci.25913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782523PMC
August 2013

Selection of antibody fragments by yeast display.

Methods Mol Biol 2012 ;907:259-80

Center for Research on Reproduction and Women's Health, Penn Ovarian Cancer Research Center, University of Pennsylvania School of Medicine, Philadelphia, PA, USA,

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http://dx.doi.org/10.1007/978-1-61779-974-7_15DOI Listing
December 2012

Coating Evaluation and Purification of Monodisperse, Water-Soluble, Magnetic Nanoparticles Using Sucrose Density Gradient Ultracentrifugation.

Chem Mater 2012 Nov 19;24(21):4008-4010. Epub 2012 Oct 19.

Penn Ovarian Cancer Research Center and Department of Obstetrics and Gynecology, University of Pennsylvania Perelman School of Medicine, University of Pennsylvania, Pennsylvania 19104, United States.

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http://dx.doi.org/10.1021/cm302582zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513279PMC
November 2012

Genetic and pharmacologic inhibition of complement impairs endothelial cell function and ablates ovarian cancer neovascularization.

Neoplasia 2012 Nov;14(11):994-1004

Penn Ovarian Cancer Research Center, Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514739PMC
http://dx.doi.org/10.1593/neo.121262DOI Listing
November 2012

Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library.

BMC Biotechnol 2012 May 7;12:23. Epub 2012 May 7.

Medicine and Research Services, Philadelphia VA Medical Center, PA 19104, USA.

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http://dx.doi.org/10.1186/1472-6750-12-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425314PMC
May 2012

A universal strategy for adoptive immunotherapy of cancer through use of a novel T-cell antigen receptor.

Cancer Res 2012 Apr 7;72(7):1844-52. Epub 2012 Feb 7.

Department of Obstetrics and Gynecology, Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319867PMC
April 2012

Redirected antitumor activity of primary human lymphocytes transduced with a fully human anti-mesothelin chimeric receptor.

Mol Ther 2012 Mar 29;20(3):633-43. Epub 2011 Nov 29.

Department of Obstetrics and Gynecology, Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/mt.2011.256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293635PMC
March 2012

Oncology biomarkers for gynecologic malignancies.

Front Biosci (Elite Ed) 2012 Jan 1;4:1097-110. Epub 2012 Jan 1.

Division of Gynecologic Oncology, University of Pennsylvania Health System, Philadelphia, PA, USA.

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January 2012

Rapid isolation of high-affinity human antibodies against the tumor vascular marker Endosialin/TEM1, using a paired yeast-display/secretory scFv library platform.

J Immunol Methods 2011 Jan 15;363(2):221-32. Epub 2010 Sep 15.

Penn Ovarian Cancer Research Center, Center for Research on Reproduction and Women's Health (CRRWH), Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002217591000239
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http://dx.doi.org/10.1016/j.jim.2010.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003766PMC
January 2011

An orthotopic model of serous ovarian cancer in immunocompetent mice for in vivo tumor imaging and monitoring of tumor immune responses.

J Vis Exp 2010 Nov 28(45). Epub 2010 Nov 28.

Penn Ovarian Cancer Research Center, Center for Research on Reproduction and Womans Health, Department of Obstetrics and Gynecology, University of Pennsylvania-School of Medicine, USA.

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http://dx.doi.org/10.3791/2146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159604PMC
November 2010

Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer.

Gynecol Oncol 2010 Mar 28;116(3):378-83. Epub 2009 Nov 28.

Molecular Diagnostics Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.

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http://dx.doi.org/10.1016/j.ygyno.2009.10.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822097PMC
March 2010

Assessing lead time of selected ovarian cancer biomarkers: a nested case-control study.

J Natl Cancer Inst 2010 Jan 30;102(1):26-38. Epub 2009 Dec 30.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, PO Box 19024, M3-A410, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1093/jnci/djp438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802285PMC
January 2010

Antifouling surface layers for improved signal-to-noise of particle-based immunoassays.

Langmuir 2009 Dec;25(23):13510-5

Biomarker Research and Development Centre, Level 5 East, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, QLD 4072, Australia.

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http://pubs.acs.org/doi/abs/10.1021/la903148n
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http://dx.doi.org/10.1021/la903148nDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891774PMC
December 2009

Beyond CA125: the coming of age of ovarian cancer biomarkers. Are we there yet?

Biomark Med 2009 Jun;3(3):275-288

University of Pennsylvania School of Medicine, 421 Curie Boulevard, BRBII/III, PA, USA.

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https://www.futuremedicine.com/doi/10.2217/bmm.09.21
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http://dx.doi.org/10.2217/bmm.09.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726755PMC
June 2009

Maternal mortality from systemic illness: unraveling the contribution of the immune response.

Am J Obstet Gynecol 2009 Apr;200(4):430.e1-8

Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.ajog.2009.01.049DOI Listing
April 2009

Oncology biomarkers--second annual GTCbio conference. Biomarkers for disease detection and therapeutics monitoring. 19-20 January 2009, Miami, FL, USA.

IDrugs 2009 Apr;12(4):207-10

University of Pennsylvania, 1309 Biomedical Research Building II/III, 421 Curie Boulevard, Philadelphia, PA 19104-6160, USA.

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April 2009

Combining a symptoms index with CA 125 to improve detection of ovarian cancer.

Cancer 2008 Aug;113(3):484-9

Molecular Diagnostics Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.

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http://dx.doi.org/10.1002/cncr.23577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734274PMC
August 2008

Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery.

J Transl Med 2008 Jul 24;6:41. Epub 2008 Jul 24.

Center for Research on Early Detection and Cure of Ovarian Cancer, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1186/1479-5876-6-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503970PMC
July 2008

Use of high density antibody arrays to validate and discover cancer serum biomarkers.

Mol Oncol 2007 Dec 30;1(3):313-20. Epub 2007 Aug 30.

Molecular Diagnostics Program, Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1016/j.molonc.2007.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671017PMC
December 2007

CA125 in ovarian cancer.

Biomark Med 2007 Dec;1(4):513-23

Center for Research on Early Detection & Cure of Ovarian Cancer School of Medicine, University of Pennsylvania Biomedical Research Building (BRB) II/III, Suite 1355 421 Curie Blvd, PA 19104-6080, USA.

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http://dx.doi.org/10.2217/17520363.1.4.513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872496PMC
December 2007

Development and in vitro validation of anti-mesothelin biobodies that prevent CA125/Mesothelin-dependent cell attachment.

Cancer Lett 2007 Oct 7;255(2):263-74. Epub 2007 Jun 7.

Molecular Diagnositics Program, Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.canlet.2007.04.012DOI Listing
October 2007

Development of a CA125-mesothelin cell adhesion assay as a screening tool for biologics discovery.

Cancer Lett 2007 Mar 4;247(1):130-6. Epub 2006 May 4.

Molecular Diagnostics Program, Public Health Sciences, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1016/j.canlet.2006.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734268PMC
March 2007

Method for generation of in vivo biotinylated recombinant antibodies by yeast mating.

J Immunol Methods 2006 Dec 30;317(1-2):132-43. Epub 2006 Oct 30.

Translational Outcomes Research Group, Molecular Diagnostics Program, Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1016/j.jim.2006.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784068PMC
December 2006

Bead-based ELISA for validation of ovarian cancer early detection markers.

Clin Cancer Res 2006 Apr;12(7 Pt 1):2117-24

Translational Outcomes Research Laboratory, Fred Hutchinson Cancer Research Center, Public Health Sciences, and Harborview Medical Center, University of Washington, Seattle, Washington, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-05-2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734269PMC
April 2006

Plasmid-based vaccines encoding rat neu and immune stimulatory molecules can elicit rat neu-specific immunity.

Mol Cancer Ther 2003 Oct;2(10):995-1002

Tumor Vaccine Group, Division of Oncology, University of Washington, Seattle, WA 98195-6527, USA.

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October 2003

Cutting edge: CD83 regulates the development of cellular immunity.

J Immunol 2002 Mar;168(6):2599-602

Laboratories of. Tumor Immunology, and Immunobiology, Pacific Northwest Research Institute, Seattle, WA 98122, USA.

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http://dx.doi.org/10.4049/jimmunol.168.6.2599DOI Listing
March 2002