Nathalie Brouwers

Nathalie Brouwers

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Nathalie Brouwers

Nathalie Brouwers

Publications by authors named "Nathalie Brouwers"

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35Publications

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GRASP55 and UPR Control Interleukin-1β Aggregation and Secretion.

Dev Cell 2019 Apr 14;49(1):145-155.e4. Epub 2019 Mar 14.

Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, Barcelona 08003, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Pg. Lluis Companys 23, Barcelona 08010, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.02.011DOI Listing
April 2019

Sodium channel TRPM4 and sodium/calcium exchangers (NCX) cooperate in the control of Ca-induced mucin secretion from goblet cells.

J Biol Chem 2019 01 27;294(3):816-826. Epub 2018 Nov 27.

From the Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, 08003 Barcelona, Spain,

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http://www.jbc.org/lookup/doi/10.1074/jbc.RA117.000848
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http://dx.doi.org/10.1074/jbc.RA117.000848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341386PMC
January 2019

Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment.

PLoS One 2017 26;12(4):e0174819. Epub 2017 Apr 26.

Cell and Developmental Biology Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174819PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405935PMC
September 2017

A diacidic motif determines unconventional secretion of wild-type and ALS-linked mutant SOD1.

J Cell Biol 2017 Aug 9. Epub 2017 Aug 9.

Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain

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http://dx.doi.org/10.1083/jcb.201704056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584182PMC
August 2017

Reduced secretion and altered proteolytic processing caused by missense mutations in progranulin.

Neurobiol Aging 2016 Mar 29;39:220.e17-26. Epub 2015 Dec 29.

Biochemistry, Biomedical Center (BMC), Ludwig-Maximilians University, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; German Center for Neurodegenerative Diseases, DZNE, Munich, Germany.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.12.014DOI Listing
March 2016

TANGO1 recruits ERGIC membranes to the endoplasmic reticulum for procollagen export.

Elife 2015 Nov 14;4. Epub 2015 Nov 14.

Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain.

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http://dx.doi.org/10.7554/eLife.10982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709264PMC
November 2015

Brain-specific tryptophan hydroxylase, TPH2, and 5-HTTLPR are associated with frontal lobe symptoms in Alzheimer's disease.

J Alzheimers Dis 2013 ;35(1):67-73

Department of Neurology and Memory Clinic, Middelheim and Hoge Beuken General Hospitals (ZNA), Antwerpen, Belgium.

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http://dx.doi.org/10.3233/JAD-101305DOI Listing
December 2013

Genetic association of CR1 with Alzheimer's disease: a tentative disease mechanism.

Neurobiol Aging 2012 Dec 21;33(12):2949.e5-2949.e12. Epub 2012 Jul 21.

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.07.001DOI Listing
December 2012

The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study.

J Alzheimers Dis 2010 ;22(1):247-55

Unité INSERM 744, Institut Pasteur de Lille BP 245,1, rue du professeur Calmette, F59019Lille cedex, France.

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http://dx.doi.org/10.3233/JAD-2010-100933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964875PMC
August 2011

Potent amyloidogenicity and pathogenicity of Aβ43.

Nat Neurosci 2011 Jul 3;14(8):1023-32. Epub 2011 Jul 3.

Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako-shi, Saitama, Japan.

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http://dx.doi.org/10.1038/nn.2858DOI Listing
July 2011

Role of progranulin as a biomarker for Alzheimer's disease.

Biomark Med 2010 Feb;4(1):37-50

Department of Molecular Genetics, CIB, Antwerpen Belgium.

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February 2010

DNMBP is genetically associated with Alzheimer dementia in the Belgian population.

Neurobiol Aging 2009 Dec 24;30(12):2000-9. Epub 2008 Mar 24.

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, University of Antwerp, Universiteitsplein 1, 2610 Antwerpen, Belgium.

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http://dx.doi.org/10.1016/j.neurobiolaging.2008.02.003DOI Listing
December 2009

APP and BACE1 miRNA genetic variability has no major role in risk for Alzheimer disease.

Hum Mutat 2009 Aug;30(8):1207-13

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium.

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http://dx.doi.org/10.1002/humu.21027DOI Listing
August 2009

Serum biomarker for progranulin-associated frontotemporal lobar degeneration.

Ann Neurol 2009 May;65(5):603-9

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB (Flanders Institute for Biotechnology), University of Antwerp, Universiteitsplein 1, Antwerp, Belgium.

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http://dx.doi.org/10.1002/ana.21621DOI Listing
May 2009

No association between CALHM1 and risk for Alzheimer dementia in a Belgian population.

Hum Mutat 2009 Apr;30(4):E570-4

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, University of Antwerp, Antwerpen, Belgium.

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http://dx.doi.org/10.1002/humu.20990DOI Listing
April 2009

Common variation in GRB-associated Binding Protein 2 (GAB2) and increased risk for Alzheimer dementia.

Hum Mutat 2009 Feb;30(2):E338-44

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, University of Antwerp - CDE, Universiteitsplein 1, B-2610 Antwerpen, Belgium.

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http://dx.doi.org/10.1002/humu.20909DOI Listing
February 2009

Molecular genetics of Alzheimer's disease: an update.

Ann Med 2008 ;40(8):562-83

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerpen, Belgium.

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http://dx.doi.org/10.1080/07853890802186905DOI Listing
January 2009

SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population.

Hum Mutat 2008 May;29(5):769-70

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, University of Antwerp, Antwerpen, Belgium.

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http://dx.doi.org/10.1002/humu.20725DOI Listing
May 2008

No association of CSF biomarkers with APOEepsilon4, plaque and tangle burden in definite Alzheimer's disease.

Brain 2007 Sep 22;130(Pt 9):2320-6. Epub 2007 Jun 22.

Department of Neurology and Memory Clinic, Middelheim General Hospital (ZNA), Antwerpen, Belgium.

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http://dx.doi.org/10.1093/brain/awm136DOI Listing
September 2007

Genetic risk and transcriptional variability of amyloid precursor protein in Alzheimer's disease.

Brain 2006 Nov 24;129(Pt 11):2984-91. Epub 2006 Aug 24.

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics Flanders Interuniversity Institute for Biotechnology Antwerpen, Belgium.

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http://dx.doi.org/10.1093/brain/awl212DOI Listing
November 2006

Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease.

Am J Hum Genet 2006 Jun 10;78(6):936-46. Epub 2006 Apr 10.

Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, University of Antwerp, Antwerpen, Belgium.

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http://dx.doi.org/10.1086/504044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474091PMC
June 2006

The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years.

Neurosci Lett 2006 Jan 6;392(1-2):72-4. Epub 2005 Oct 6.

Department of Molecular Genetics, Flanders Interuniversity Institute of Biotechnology and Institute Born-Bunge, University of Antwerp, Universiteitsplein 1, Belgium.

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http://dx.doi.org/10.1016/j.neulet.2005.08.064DOI Listing
January 2006