Natarajan Muthusamy

Natarajan Muthusamy

UNVERIFIED PROFILE

Are you Natarajan Muthusamy?   Register this Author

Register author
Natarajan Muthusamy

Natarajan Muthusamy

Publications by authors named "Natarajan Muthusamy"

Are you Natarajan Muthusamy?   Register this Author

96Publications

2179Reads

47Profile Views

Leukemic B Cell CTLA-4 Suppresses Costimulation of T Cells.

J Immunol 2019 May 25;202(9):2806-2816. Epub 2019 Mar 25.

Department of Internal Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1801359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478536PMC
May 2019

Chronic Lymphocytic Leukemia-Derived IL-10 Suppresses Antitumor Immunity.

J Immunol 2018 06 30;200(12):4180-4189. Epub 2018 Apr 30.

Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, KY 40536;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1800241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555426PMC
June 2018

Microbial fuel cell characterisation and evaluation of Lysinibacillus macroides MFC02 electrigenic capability.

World J Microbiol Biotechnol 2017 May 8;33(5):91. Epub 2017 Apr 8.

Department of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamil Nadu, India.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11274-017-2252-3
Publisher Site
http://dx.doi.org/10.1007/s11274-017-2252-3DOI Listing
May 2017

Therapeutic CD94/NKG2A blockade improves natural killer cell dysfunction in chronic lymphocytic leukemia.

Oncoimmunology 2016 9;5(10):e1226720. Epub 2016 Sep 9.

Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, The Ohio State University , Columbus, OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/2162402X.2016.1226720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087289PMC
September 2016

Lenalidomide Induces Interleukin-21 Production by T Cells and Enhances IL21-Mediated Cytotoxicity in Chronic Lymphocytic Leukemia B Cells.

Cancer Immunol Res 2016 08 10;4(8):698-707. Epub 2016 Jun 10.

Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2326-6066.CIR-15-0291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909974PMC
August 2016

Role of B cell receptor signaling in IL-10 production by normal and malignant B-1 cells.

Ann N Y Acad Sci 2015 Dec 11;1362:239-249. Epub 2015 Jun 11.

Department of Microbiology, Immunology and Molecular Genetics, Markey Cancer Center, University of Kentucky, Lexington, Kentucky.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/nyas.12802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676736PMC
December 2015

ROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo.

Exp Hematol 2015 Sep 29;43(9):770-4.e2. Epub 2015 Apr 29.

Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2015.04.008DOI Listing
September 2015

CD33-Targeted Lipid Nanoparticles (aCD33LNs) for Therapeutic Delivery of GTI-2040 to Acute Myelogenous Leukemia.

Mol Pharm 2015 Jun 28;12(6):2010-8. Epub 2015 Apr 28.

†Division of Pharmaceutics, College of Pharmacy, ‡Division of Hematology-Oncology, §Molecular, Cellular and Developmental Biology Program, and ∥Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio 43210, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/mp5008212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962870PMC
June 2015

CpG oligodeoxynucleotide CpG-685 upregulates functional interleukin-21 receptor on chronic lymphocytic leukemia B cells through an NF-κB mediated pathway.

Oncotarget 2015 Jun;6(18):15931-9

Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599247PMC
http://dx.doi.org/10.18632/oncotarget.3285DOI Listing
June 2015

Ocaratuzumab, an Fc-engineered antibody demonstrates enhanced antibody-dependent cell-mediated cytotoxicity in chronic lymphocytic leukemia.

MAbs 2014 May-Jun;6(3):749-55. Epub 2014 Mar 4.

Division of Hematology; Department of Internal Medicine; The Ohio State University; Columbus, OH USA; Division of Medicinal Chemistry; College of Pharmacy; The Ohio State University; Columbus, OH USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/mabs.28282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011919PMC
May 2015

Tetraspanins as therapeutic targets in hematological malignancy: a concise review.

Front Physiol 2015 23;6:91. Epub 2015 Mar 23.

Division of Hematology, Department of Internal Medicine, The Ohio State University Columbus, OH, USA ; Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University Columbus, OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphys.2015.00091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369647PMC
April 2015

A novel liposomal formulation of FTY720 (fingolimod) for promising enhanced targeted delivery.

Nanomedicine 2014 Feb 20;10(2):393-400. Epub 2013 Aug 20.

Division of Hematology and Oncology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nano.2013.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134520PMC
February 2014

Antibody-based therapeutics for the treatment of human B cell malignancies.

Curr Allergy Asthma Rep 2013 Feb;13(1):33-43

Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11882-012-0327-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674564PMC
February 2013

Milatuzumab-conjugated liposomes as targeted dexamethasone carriers for therapeutic delivery in CD74+ B-cell malignancies.

Clin Cancer Res 2013 Jan 3;19(2):347-56. Epub 2012 Dec 3.

Division of Hematology, The Comprehensive Cancer Center, Division of Pharmaceutics and Medicinal Chemistry, College of Pharmacy, Ohio State University, Columbus, OH 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-12-2046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793126PMC
January 2013

Synthetic microRNA cassette dosing: pharmacokinetics, tissue distribution and bioactivity.

Mol Pharm 2012 Jun 23;9(6):1638-44. Epub 2012 May 23.

Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210,United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/mp2006483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977775PMC
June 2012

Role for Ets-2(Thr-72) transcription factor in stage-specific thymocyte development and survival.

J Biol Chem 2012 Feb 29;287(8):5199-210. Epub 2011 Nov 29.

Molecular Cellular Developmental Biology Program, Division of Hematology, Ohio State University, Columbus, Ohio 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M111.242602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285301PMC
February 2012

The clinical application of monoclonal antibodies in chronic lymphocytic leukemia.

Blood 2010 Nov 7;116(19):3705-14. Epub 2010 Jul 7.

Division of Hematology-Oncology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA.

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-04-00
Publisher Site
http://dx.doi.org/10.1182/blood-2010-04-001230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981531PMC
November 2010

Arsenic trioxide and ascorbic acid demonstrate promising activity against primary human CLL cells in vitro.

Leuk Res 2010 Jul 19;34(7):925-31. Epub 2010 Feb 19.

Division of Hematology and Oncology, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.leukres.2010.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164821PMC
July 2010

Targeted delivery of antisense oligodeoxynucleotide by transferrin conjugated pH-sensitive lipopolyplex nanoparticles: a novel oligonucleotide-based therapeutic strategy in acute myeloid leukemia.

Mol Pharm 2010 Feb;7(1):196-206

NSF Nanoscale Science and Engineering Center, Division of Pharmaceutics, College of Pharmacy, Department of Chemical and Biomolecular Engineering, The Comprehensive Cancer Center, and Division of Hematology and Oncology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/mp900205rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342499PMC
February 2010

Liposomal coencapsulated fludarabine and mitoxantrone for lymphoproliferative disorder treatment.

J Pharm Sci 2008 Apr;97(4):1508-18

Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jps.21046DOI Listing
April 2008

Disruption of ZAS3 in mice alters NF-kappaB and AP-1 DNA binding and T-cell development.

Gene Expr 2007 ;14(2):83-100

Department of Pediatrics and Center for Cell and Developmental Biology, Columbus Children's Research Institute, Columbus, OH 43205, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042042PMC
http://dx.doi.org/10.3727/105221607783417574DOI Listing
March 2008

FTY720 induces apoptosis in hepatocellular carcinoma cells through activation of protein kinase C delta signaling.

Cancer Res 2008 Feb;68(4):1204-12

Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-07-2621DOI Listing
February 2008

Cholesterol as a bilayer anchor for PEGylation and targeting ligand in folate-receptor-targeted liposomes.

J Pharm Sci 2007 Sep;96(9):2424-35

Division of Pharmaceutics, NCI OSU Comprehensive Cancer Center, NSF Nanoscales Science and Engineering Center (NSEC), College of Pharmacy, The Ohio State University, 542 LM Parks Hall, 500 W. 12th Ave, Columbus, Ohio 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jps.20885DOI Listing
September 2007

Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis.

Proc Natl Acad Sci U S A 2007 Sep 19;104(39):15400-5. Epub 2007 Sep 19.

Human Cancer Genetics Program, Department of Molecular Virology, Immunology, and Medical Genetics, College of Medicine and Public Health, Ohio State University, Columbus, OH 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0706307104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000495PMC
September 2007

Differential role for cyclic AMP response element binding protein-1 in multiple stages of B cell development, differentiation, and survival.

J Immunol 2006 Feb;176(4):2208-18

Division of Hematology and Oncology, Department of Internal Medicine, The Ohio State University, Columbus, 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.176.4.2208DOI Listing
February 2006

Impaired antigen receptor induced calcium mobilization in a phospholipase C-gamma1 deficient B cell line.

Immunol Lett 2003 Dec;90(2-3):203-7

Center for Molecular and Human Genetics, The Department of Pediatrics, Columbus Children's Research Institute, The Ohio State University Columbus, OH 43205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.imlet.2003.09.010DOI Listing
December 2003

Activation induced differential regulation of stem cell antigen-1 (Ly-6A/E) expression in murine B cells.

Cell Immunol 2003 Sep;225(1):42-52

Department of Pediatrics, Center for Human and Molecular Genetics, Columbus Children's Research Institute, The Ohio State University, Columbus, OH 43205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellimm.2003.09.006DOI Listing
September 2003

IFN-gamma-mediated inhibition of antigen receptor-induced B cell proliferation and CREB-1 binding activity requires STAT-1 transcription factor.

Eur J Immunol 2003 Apr;33(4):907-12

Children's Research Institute, Wexner Institute for Pediatric Research, Columbus, OH 43205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.200323657DOI Listing
April 2003

Developmental anomalies and neoplasia in animals and cells deficient in the large zinc finger protein KRC.

Genes Chromosomes Cancer 2002 Dec;35(4):287-98

Program of Molecular, Cellular, and Developmental Biology, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/gcc.10128
Publisher Site
http://dx.doi.org/10.1002/gcc.10128DOI Listing
December 2002

Human T-cell lymphotropic virus type 1 p12(I) expression increases cytoplasmic calcium to enhance the activation of nuclear factor of activated T cells.

J Virol 2002 Oct;76(20):10374-82

Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, 1925 Coffey Road, Columbus, OH 43210, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC136546PMC
http://dx.doi.org/10.1128/jvi.76.20.10374-10382.2002DOI Listing
October 2002

Role of macrophage-colony stimulating factor and osteoclast differentiation factor in osteoclastogenesis of bone marrow derived stem cells.

Indian J Exp Biol 2002 Sep;40(9):995-1000

Pediatrics; Division of Hematology and Oncology, Children's Hospital of Columbus, OH, USA.

View Article

Download full-text PDF

Source
September 2002