Natalia S Pellegata

Natalia S Pellegata

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Natalia S Pellegata

Natalia S Pellegata

Publications by authors named "Natalia S Pellegata"

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Adiponectin affects the mechanical responses in strips from the mouse gastric fundus.

World J Gastroenterol 2018 Sep;24(35):4028-4035

Department of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, Florence 50134, Italy.

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http://dx.doi.org/10.3748/wjg.v24.i35.4028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148421PMC
September 2018

Animal models of MEN1.

Endocr Relat Cancer 2017 10 25;24(10):T161-T177. Epub 2017 Jul 25.

Institute for Diabetes and CancerHelmholtz Zentrum München, Neuherberg, Germany

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http://dx.doi.org/10.1530/ERC-17-0249DOI Listing
October 2017

Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo.

Endocr Relat Cancer 2017 01 3;24(1):1-15. Epub 2016 Nov 3.

Institute for Diabetes and CancerHelmholtz Zentrum München, Neuherberg, Germany

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http://dx.doi.org/10.1530/ERC-16-0324DOI Listing
January 2017

Morphology, Biochemistry, and Pathophysiology of MENX-Related Pheochromocytoma Recapitulate the Clinical Features.

Endocrinology 2016 08 2;157(8):3157-66. Epub 2016 Jun 2.

Institute for Diabetes and Cancer (T.W., N.S.P.) and Institute of Experimental Genetics (F.N.), Helmholtz Zentrum München, 85764 Neuherberg, Germany; Institute of Clinical Chemistry and Laboratory Medicine (M.P., N.Q., G.E.), University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, and Department of Internal Medicine III (M.P., N.Q., G.E.), University Hospital Carl Gustav Carus, and Division of Molecular Endocrinology (M.E.-B., G.E.), Medical Clinic III, Technische Universität Dresden, 01307 Dresden, Germany.

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http://dx.doi.org/10.1210/en.2016-1108DOI Listing
August 2016

Primary Cell Culture Systems for Human Thyroid Studies.

Thyroid 2016 08 6;26(8):1131-40. Epub 2016 Jul 6.

1 Human Cancer Genetics Program and Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, The Ohio State University , Columbus, Ohio.

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http://dx.doi.org/10.1089/thy.2015.0518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976228PMC
August 2016

Animal models of multiple endocrine neoplasia.

Mol Cell Endocrinol 2016 Feb 13;421:49-59. Epub 2015 Jul 13.

Institute of Pathology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2015.07.004DOI Listing
February 2016

Obesity in MENX Rats Is Accompanied by High Circulating Levels of Ghrelin and Improved Insulin Sensitivity.

Diabetes 2016 Feb 28;65(2):406-20. Epub 2015 Oct 28.

Institute of Pathology, Helmholtz Center Munich, German Research Center for Environmental Health, Technical University Munich, Munich, Germany

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http://dx.doi.org/10.2337/db15-0374DOI Listing
February 2016

Acromegaly due to a Macroinvasive Plurihormonal Pituitary Adenoma and a Rectal Carcinoid Tumor.

Endocrinol Metab (Seoul) 2015 Sep 5;30(3):389-94. Epub 2015 Jan 5.

Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3803/EnM.2015.30.3.389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595365PMC
September 2015

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

Authors:
Martin Hrabě de Angelis George Nicholson Mohammed Selloum Jacqui White Hugh Morgan Ramiro Ramirez-Solis Tania Sorg Sara Wells Helmut Fuchs Martin Fray David J Adams Niels C Adams Thure Adler Antonio Aguilar-Pimentel Dalila Ali-Hadji Gregory Amann Philippe André Sarah Atkins Aurelie Auburtin Abdel Ayadi Julien Becker Lore Becker Elodie Bedu Raffi Bekeredjian Marie-Christine Birling Andrew Blake Joanna Bottomley Mike Bowl Véronique Brault Dirk H Busch James N Bussell Julia Calzada-Wack Heather Cater Marie-France Champy Philippe Charles Claire Chevalier Francesco Chiani Gemma F Codner Roy Combe Roger Cox Emilie Dalloneau André Dierich Armida Di Fenza Brendan Doe Arnaud Duchon Oliver Eickelberg Chris T Esapa Lahcen El Fertak Tanja Feigel Irina Emelyanova Jeanne Estabel Jack Favor Ann Flenniken Alessia Gambadoro Lilian Garrett Hilary Gates Anna-Karin Gerdin George Gkoutos Simon Greenaway Lisa Glasl Patrice Goetz Isabelle Goncalves Da Cruz Alexander Götz Jochen Graw Alain Guimond Wolfgang Hans Geoff Hicks Sabine M Hölter Heinz Höfler John M Hancock Robert Hoehndorf Tertius Hough Richard Houghton Anja Hurt Boris Ivandic Hughes Jacobs Sylvie Jacquot Nora Jones Natasha A Karp Hugo A Katus Sharon Kitchen Tanja Klein-Rodewald Martin Klingenspor Thomas Klopstock Valerie Lalanne Sophie Leblanc Christoph Lengger Elise le Marchand Tonia Ludwig Aline Lux Colin McKerlie Holger Maier Jean-Louis Mandel Susan Marschall Manuel Mark David G Melvin Hamid Meziane Kateryna Micklich Christophe Mittelhauser Laurent Monassier David Moulaert Stéphanie Muller Beatrix Naton Frauke Neff Patrick M Nolan Lauryl Mj Nutter Markus Ollert Guillaume Pavlovic Natalia S Pellegata Emilie Peter Benoit Petit-Demoulière Amanda Pickard Christine Podrini Paul Potter Laurent Pouilly Oliver Puk David Richardson Stephane Rousseau Leticia Quintanilla-Fend Mohamed M Quwailid Ildiko Racz Birgit Rathkolb Fabrice Riet Janet Rossant Michel Roux Jan Rozman Ed Ryder Jennifer Salisbury Luis Santos Karl-Heinz Schäble Evelyn Schiller Anja Schrewe Holger Schulz Ralf Steinkamp Michelle Simon Michelle Stewart Claudia Stöger Tobias Stöger Minxuan Sun David Sunter Lydia Teboul Isabelle Tilly Glauco P Tocchini-Valentini Monica Tost Irina Treise Laurent Vasseur Emilie Velot Daniela Vogt-Weisenhorn Christelle Wagner Alison Walling Bruno Weber Olivia Wendling Henrik Westerberg Monja Willershäuser Eckhard Wolf Anne Wolter Joe Wood Wolfgang Wurst Ali Önder Yildirim Ramona Zeh Andreas Zimmer Annemarie Zimprich Chris Holmes Karen P Steel Yann Herault Valérie Gailus-Durner Ann-Marie Mallon Steve Dm Brown

Nat Genet 2015 Sep 27;47(9):969-978. Epub 2015 Jul 27.

MRC Harwell, Medical Research Council, Harwell, UK.

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http://dx.doi.org/10.1038/ng.3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564951PMC
September 2015

Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against Nonfunctioning Pituitary Adenomas.

Clin Cancer Res 2015 Jul 2;21(14):3204-15. Epub 2015 Apr 2.

Institute of Pathology, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0288DOI Listing
July 2015

Adrenomedullary progenitor cells: Isolation and characterization of a multi-potent progenitor cell population.

Mol Cell Endocrinol 2015 Jun 6;408:178-84. Epub 2015 Jan 6.

Division of Molecular Endocrinology, Medical Clinic III, Carl Gustav Carus University Clinic, Technische Universität Dresden, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden, Technische Universität Dresden, 01307 Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2014.12.020DOI Listing
June 2015

Early onset acromegaly associated with a novel deletion in CDKN1B 5'UTR region.

Endocrine 2015 May 4;49(1):58-64. Epub 2015 Feb 4.

Section of Endocrinology and Internal Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1007/s12020-015-0540-yDOI Listing
May 2015

Functional characterization of a CDKN1B mutation in a Sardinian kindred with multiple endocrine neoplasia type 4 (MEN4).

Endocr Connect 2015 03 21;4(1):1-8. Epub 2014 Nov 21.

F Cetani, Department of Clinical and Experimental Medicine, University of Pisa, Endocrine Unit 2, University Hospital of Pisa, Pisa, Italy

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http://dx.doi.org/10.1530/EC-14-0116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713151PMC
March 2015

SSTR3 is a putative target for the medical treatment of gonadotroph adenomas of the pituitary.

Endocr Relat Cancer 2015 Feb 16;22(1):111-9. Epub 2014 Dec 16.

Institute of PathologyHelmholtz Zentrum München, D-85764 Neuherberg, GermanyDepartment of Pharmacology and ToxicologyJena University Hospital, Friedrich Schiller University, Jena, GermanyDepartments of NeurosurgeryMedicineImperial College, St Dunstans Road, London W6 8RP, UKDepartment of NeuropathologyInstitute for Pathology and NeuropathologyDepartment of NeurosurgeryUniversity of Tübingen, Tübingen, GermanyInstitute of PathologyTechnical University of Munich, München, Germany

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http://www.sfb824.de/pdf/Publikationen/Artikel_Pelegata_B8.p
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http://erc.endocrinology-journals.org/cgi/doi/10.1530/ERC-14
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http://dx.doi.org/10.1530/ERC-14-0472DOI Listing
February 2015

Association between the p27 rs2066827 variant and tumor multiplicity in patients harboring MEN1 germline mutations.

Eur J Endocrinol 2014 Sep 11;171(3):335-42. Epub 2014 Jun 11.

Endocrine Genetics Unit (Laboratorio de Investigacao Medica/LIM-25)Neuroendocrinology UnitNeuroendocrinology-Neurosurgery UnitAdrenal Unit (LIM-42)General Endocrinology UnitExperimental Oncology Laboratory (LIM-24)Department of PathologyNursing SchoolSchool of Public Health of Hospital das ClínicasUniversity of Sao Paulo School of Medicine, Sao Paulo, BrazilBrigadeiro HospitalSao Paulo, BrazilHuman Genome Research CenterUniversity of Sao Paulo, Sao Paulo, BrazilInstituto do CérebroInstituto Israelita de Ensino e Pesquisa Albert Einstein, Sao Paulo, BrazilNational Institute of AgingNational Institutes of Health (NIH), Bethesda, Maryland, USAInstitute of PathologyHelmholtz Zentrum München, Neuherberg, GermanyInstitute of Biomedical SciencesUniversity of Sao Paulo, Sao Paulo, BrazilDivision of EndocrinologyFederal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil

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http://dx.doi.org/10.1530/EJE-14-0130DOI Listing
September 2014

p27 variant and corticotropinoma susceptibility: a genetic and in vitro study.

Endocr Relat Cancer 2014 06 28;21(3):395-404. Epub 2014 Apr 28.

Endocrine Genetics Unit LIM-25 Neuroendocrinology Unit Adrenal Unit (LIM-42) Experimental Oncology Laboratory (LIM-24), School of Medicine, Hospital das Clinicas, University of Sao Paulo, Sao Paulo, Brazil Nursing School School of Public Health, University of Sao Paulo, Sao Paulo, Brazil Endocrinology Division, Santa Casa Hospital, Sao Paulo, Brazil Brigadeiro Hospital, Sao Paulo, Brazil Federal University of Sao Paulo, Sao Paulo, Brazil Human Genome Research Center Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Sao Paulo, Brazil Instituto do Cérebro, Instituto Israelita de Ensino e Pesquisa Albert Einstein, Sao Paulo, Brazil National Institute of Aging, National Institutes of Health (NIH), Bethesda, Maryland, USA Institute of Pathology, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1530/ERC-13-0486DOI Listing
June 2014

Multiple endocrine neoplasia type 4.

Front Horm Res 2013 19;41:63-78. Epub 2013 Mar 19.

Institute of Pathology, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1159/000345670DOI Listing
December 2013

Preclinical evaluation of 18F-LMI1195 for in vivo imaging of pheochromocytoma in the MENX tumor model.

J Nucl Med 2013 Dec 17;54(12):2111-7. Epub 2013 Oct 17.

Klinikum Rechts der Isar der Technischen Universität München, Nuklearmedizinische Klinik, München, Germany.

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http://dx.doi.org/10.2967/jnumed.113.119966DOI Listing
December 2013

Folate receptor-mediated drug targeting: a possible strategy for nonfunctioning pituitary adenomas?

Endocrinology 2013 Apr;154(4):1387-9

Institute of Pathology, Helmholtz Zentrum München, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1210/en.2013-1182DOI Listing
April 2013

MENX and MEN4.

Clinics (Sao Paulo) 2012 ;67 Suppl 1:13-8

Institute of Pathology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328816PMC
http://dx.doi.org/10.6061/clinics/2012(sup01)04DOI Listing
January 2013

Secretin receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway.

Mol Endocrinol 2012 Aug 12;26(8):1394-405. Epub 2012 Jun 12.

Institute of Pathology, Helmholtz Zentrum München, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1210/me.2012-1055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416982PMC
August 2012

Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: relevance for incretin-based diabetes therapy.

Neuroendocrinology 2011 2;94(4):291-301. Epub 2011 Sep 2.

Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Berne, Switzerland.

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http://dx.doi.org/10.1159/000330447DOI Listing
April 2012

MENX.

Ann Endocrinol (Paris) 2012 Apr 25;73(2):65-70. Epub 2012 Apr 25.

Institute of Pathology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.ando.2012.04.001DOI Listing
April 2012

Levels of p27 sensitize to dual PI3K/mTOR inhibition.

Mol Cancer Ther 2011 Aug 6;10(8):1450-9. Epub 2011 Jun 6.

Institute of Pathology, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0188DOI Listing
August 2011

p27kip1: a new multiple endocrine neoplasia gene?

Neuroendocrinology 2011 27;93(1):19-28. Epub 2010 Oct 27.

Institute of Pathology, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1159/000320366DOI Listing
June 2011

Somatic mutation and germline sequence abnormalities in CDKN1B, encoding p27Kip1, in sporadic parathyroid adenomas.

J Clin Endocrinol Metab 2011 Apr 2;96(4):E701-6. Epub 2011 Feb 2.

Center for Molecular Medicine, University of Connecticut Health Center, Farmington, Connecticut 06030-3101, USA.

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http://dx.doi.org/10.1210/jc.2010-1338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070245PMC
April 2011

The MENX syndrome and p27: relationships with multiple endocrine neoplasia.

Prog Brain Res 2010 ;182:295-320

Institute of Pathology, Helmholtz Zentrum Munchen-German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1016/S0079-6123(10)82013-8DOI Listing
September 2010

Allelic loss of chromosomes 8 and 19 in MENX-associated rat pheochromocytoma.

Int J Cancer 2010 May;126(10):2362-72

Institute of Pathology, Helmholtz Zentrum München-German Research Center for Environment and Health, Neuherberg, Germany.

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http://dx.doi.org/10.1002/ijc.24925DOI Listing
May 2010

Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors.

Mol Cancer 2010 May 21;9:116. Epub 2010 May 21.

Institute of Pathology, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1186/1476-4598-9-116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881881PMC
May 2010

Glucagon cell adenomatosis: a newly recognized disease of the endocrine pancreas.

J Clin Endocrinol Metab 2009 Jan 28;94(1):213-7. Epub 2008 Oct 28.

Department of Pathology, University of Tübingen, Liebermeisterstr. 8, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1210/jc.2008-1300DOI Listing
January 2009

Intracellular versican expression in mesenchymal spindle cell tumors contrasts with extracellular expression in epithelial and other tumors--a tissue microarray-based study.

Appl Immunohistochem Mol Morphol 2008 May;16(3):263-6

Department of Pathology, The Ohio State University Medical center, Columbus, OH, USA.

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http://dx.doi.org/10.1097/PAI.0b013e31812cb5bcDOI Listing
May 2008

Human pheochromocytomas show reduced p27Kip1 expression that is not associated with somatic gene mutations and rarely with deletions.

Virchows Arch 2007 Jul 7;451(1):37-46. Epub 2007 Jun 7.

Institute of Pathology, GSF-National Research Center for Environment and Health, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00428-007-0431-6DOI Listing
July 2007

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans.

Proc Natl Acad Sci U S A 2006 Oct 9;103(42):15558-63. Epub 2006 Oct 9.

Institutes of Pathology, GSF-National Research Center for Environment and Health, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1073/pnas.0603877103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1622862PMC
October 2006

Mapping of a novel MEN-like syndrome locus to rat chromosome 4.

Mamm Genome 2004 Feb;15(2):135-41

Institute of Pathology, GSF-National Research Center for Environment and Health, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-003-3027-8DOI Listing
February 2004

Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma.

Int J Cancer 2003 May;104(6):735-44

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1002/ijc.11006DOI Listing
May 2003

Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53.

Proc Natl Acad Sci U S A 2002 Nov 15;99(24):15632-7. Epub 2002 Nov 15.

Human Cancer Genetics Program, Comprehensive Cancer Center, Ohio State University, 420 West 12th Avenue, Columbus 43210, USA.

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http://dx.doi.org/10.1073/pnas.242597299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137768PMC
November 2002