Natalia Garcia-Giralt

Natalia Garcia-Giralt

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Natalia Garcia-Giralt

Natalia Garcia-Giralt

Publications by authors named "Natalia Garcia-Giralt"

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45Publications

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Increased Fracture Risk in Women Treated With Aromatase Inhibitors Versus Tamoxifen: Beneficial Effect of Bisphosphonates.

J Bone Miner Res 2019 Oct 9. Epub 2019 Oct 9.

Hospital del Mar Research Institute (IMIM), Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Barcelona, Spain.

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http://dx.doi.org/10.1002/jbmr.3886DOI Listing
October 2019

Assessment of early therapy discontinuation and health-related quality of life in breast cancer patients treated with aromatase inhibitors: B-ABLE cohort study.

Breast Cancer Res Treat 2019 Aug 24;177(1):53-60. Epub 2019 May 24.

IMIM (Hospital del Mar Research Institute), Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), 88 Doctor Aiguader Street, 08003, Barcelona, Spain.

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http://dx.doi.org/10.1007/s10549-019-05289-7DOI Listing
August 2019

Functional characterization of the C7ORF76 genomic region, a prominent GWAS signal for osteoporosis in 7q21.3.

Bone 2019 Jun 14;123:39-47. Epub 2019 Mar 14.

Department of Genetics, Microbiology and Statistics, Facultat de Biologia, Universitat de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), ISCIII, IBUB, IRSJD, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2019.03.014DOI Listing
June 2019

Pro-osteoporotic miR-320a impairs osteoblast function and induces oxidative stress.

PLoS One 2018 28;13(11):e0208131. Epub 2018 Nov 28.

Musculoskeletal Research Group, IMIM (Hospital del Mar Medical Research Institute), Centro de Investigación Biomédica en Red en Fragilidad y Envejecimiento Saludable (CIBERFES), ISCIII, Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208131PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261634PMC
May 2019

Circulating miR-103a-3p and miR-660-5p are associated with bone parameters in patients with controlled acromegaly.

Endocr Connect 2019 Jan;8(1):39-49

Endocrinology/Medicine Department, Hospital Sant Pau, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER, Unidad 747), IIB-Sant Pau, ISCIII and Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.

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http://dx.doi.org/10.1530/EC-18-0482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330718PMC
January 2019

Functional Characterization of a GGPPS Variant Identified in Atypical Femoral Fracture Patients and Delineation of the Role of GGPPS in Bone-Relevant Cell Types.

J Bone Miner Res 2018 12 24;33(12):2091-2098. Epub 2018 Sep 24.

Musculoskeletal Research Group, IMIM (Hospital del Mar Medical Research Institute), Centro de Investigación Biomédica en Red en Fragilidad y Envejecimiento Saludable (CIBERFES), ISCIII, Barcelona, Spain.

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http://dx.doi.org/10.1002/jbmr.3580DOI Listing
December 2018

Bone health evaluation one year after aromatase inhibitors completion.

Bone 2018 12 14;117:54-59. Epub 2018 Sep 14.

IMIM (Hospital del Mar Research Institute), Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Barcelona, Spain; Internal Medicine Department, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bone.2018.09.010DOI Listing
December 2018

Vitamin D levels in Mediterranean breast cancer patients compared with those in healthy women.

Maturitas 2018 Oct 29;116:83-88. Epub 2018 Jul 29.

IMIM (Hospital del Mar Research Institute), Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Barcelona, Spain; Internal Medicine Department, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.maturitas.2018.07.015DOI Listing
October 2018

Common and rare variants of WNT16, DKK1 and SOST and their relationship with bone mineral density.

Sci Rep 2018 Jul 19;8(1):10951. Epub 2018 Jul 19.

Department of Genetics, Microbiology and Statistics, Faculty of Biology, University of Barcelona, IBUB, IRSJD, CIBERER, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41598-018-29242-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053384PMC
July 2018

Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density.

Ann Rheum Dis 2018 03 23;77(3):378-385. Epub 2017 Nov 23.

Rheumatology and Bone Disease Unit, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1136/annrheumdis-2017-212469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912156PMC
March 2018

Expression profiling of microRNAs in human bone tissue from postmenopausal women.

Hum Cell 2018 Jan 20;31(1):33-41. Epub 2017 Sep 20.

Musculoskeletal Research Group, IMIM (Hospital del Mar Medical Research Institute), Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), ISCIII, C/Dr. Aiguader 88, 08003, Barcelona, Spain.

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http://dx.doi.org/10.1007/s13577-017-0181-yDOI Listing
January 2018

Fracture during oral bisphosphonate therapy is associated with deteriorated bone material strength index.

Bone 2017 Oct 24;103:64-69. Epub 2017 Jun 24.

IMIM (Hospital del Mar Research Institute), CIBERFES, Barcelona, Spain; Internal Medicine Department, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2017.06.018DOI Listing
October 2017

Effect of chondroitin sulphate on synovitis of knee osteoarthritic patients.

Med Clin (Barc) 2017 Jul 27;149(1):9-16. Epub 2017 Feb 27.

Instituto de Investigación Médica Hospital del Mar (IMIM), Barcelona, España; Unidad de Reumatología, Hospital del Mar, Barcelona, España.

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http://dx.doi.org/10.1016/j.medcli.2016.12.045DOI Listing
July 2017

Erratum to: MiRNA profiling of whole trabecular bone: identification of osteoporosis-related changes in MiRNAs in human hip bones.

BMC Med Genomics 2017 05 23;10(1):36. Epub 2017 May 23.

Musculoskeletal research group, IMIM (Hospital del Mar Medical Research Institute), Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF), ISCIII, Barcelona, Spain.

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http://dx.doi.org/10.1186/s12920-017-0272-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442687PMC
May 2017

TBS and BMD at the end of AI-therapy: A prospective study of the B-ABLE cohort.

Bone 2016 11 9;92:1-8. Epub 2016 Aug 9.

IMIM (Hospital del Mar Research Institute), Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF), Barcelona, Spain; Internal Medicine Department, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bone.2016.08.008DOI Listing
November 2016

AI-related BMD variation in actual practice conditions: A prospective cohort study.

Endocr Relat Cancer 2016 Apr 24;23(4):303-12. Epub 2016 Feb 24.

IMIM (Hospital del Mar Research Institute)Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF), Barcelona, Spain Internal Medicine DepartmentHospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1530/ERC-16-0025DOI Listing
April 2016

MiRNA profiling of whole trabecular bone: identification of osteoporosis-related changes in MiRNAs in human hip bones.

BMC Med Genomics 2015 Nov 10;8:75. Epub 2015 Nov 10.

Musculoskeletal research group, IMIM (Hospital del Mar Medical Research Institute), Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF), ISCIII, Barcelona, Spain.

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http://dx.doi.org/10.1186/s12920-015-0149-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640351PMC
November 2015

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Authors:
Hou-Feng Zheng Vincenzo Forgetta Yi-Hsiang Hsu Karol Estrada Alberto Rosello-Diez Paul J Leo Chitra L Dahia Kyung Hyun Park-Min Jonathan H Tobias Charles Kooperberg Aaron Kleinman Unnur Styrkarsdottir Ching-Ti Liu Charlotta Uggla Daniel S Evans Carrie M Nielson Klaudia Walter Ulrika Pettersson-Kymmer Shane McCarthy Joel Eriksson Tony Kwan Mila Jhamai Katerina Trajanoska Yasin Memari Josine Min Jie Huang Petr Danecek Beth Wilmot Rui Li Wen-Chi Chou Lauren E Mokry Alireza Moayyeri Melina Claussnitzer Chia-Ho Cheng Warren Cheung Carolina Medina-Gómez Bing Ge Shu-Huang Chen Kwangbom Choi Ling Oei James Fraser Robert Kraaij Matthew A Hibbs Celia L Gregson Denis Paquette Albert Hofman Carl Wibom Gregory J Tranah Mhairi Marshall Brooke B Gardiner Katie Cremin Paul Auer Li Hsu Sue Ring Joyce Y Tung Gudmar Thorleifsson Anke W Enneman Natasja M van Schoor Lisette C P G M de Groot Nathalie van der Velde Beatrice Melin John P Kemp Claus Christiansen Adrian Sayers Yanhua Zhou Sophie Calderari Jeroen van Rooij Chris Carlson Ulrike Peters Soizik Berlivet Josée Dostie Andre G Uitterlinden Stephen R Williams Charles Farber Daniel Grinberg Andrea Z LaCroix Jeff Haessler Daniel I Chasman Franco Giulianini Lynda M Rose Paul M Ridker John A Eisman Tuan V Nguyen Jacqueline R Center Xavier Nogues Natalia Garcia-Giralt Lenore L Launer Vilmunder Gudnason Dan Mellström Liesbeth Vandenput Najaf Amin Cornelia M van Duijn Magnus K Karlsson Östen Ljunggren Olle Svensson Göran Hallmans François Rousseau Sylvie Giroux Johanne Bussière Pascal P Arp Fjorda Koromani Richard L Prince Joshua R Lewis Bente L Langdahl A Pernille Hermann Jens-Erik B Jensen Stephen Kaptoge Kay-Tee Khaw Jonathan Reeve Melissa M Formosa Angela Xuereb-Anastasi Kristina Åkesson Fiona E McGuigan Gaurav Garg Jose M Olmos Maria T Zarrabeitia Jose A Riancho Stuart H Ralston Nerea Alonso Xi Jiang David Goltzman Tomi Pastinen Elin Grundberg Dominique Gauguier Eric S Orwoll David Karasik George Davey-Smith Albert V Smith Kristin Siggeirsdottir Tamara B Harris M Carola Zillikens Joyce B J van Meurs Unnur Thorsteinsdottir Matthew T Maurano Nicholas J Timpson Nicole Soranzo Richard Durbin Scott G Wilson Evangelia E Ntzani Matthew A Brown Kari Stefansson David A Hinds Tim Spector L Adrienne Cupples Claes Ohlsson Celia M T Greenwood Rebecca D Jackson David W Rowe Cynthia A Loomis David M Evans Cheryl L Ackert-Bicknell Alexandra L Joyner Emma L Duncan Douglas P Kiel Fernando Rivadeneira J Brent Richards

Nature 2015 Oct 14;526(7571):112-7. Epub 2015 Sep 14.

Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal H3A 1A2, Canada.

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http://dx.doi.org/10.1038/nature14878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755714PMC
October 2015

Skeletal adverse effects with aromatase inhibitors in early breast cancer: evidence to date and clinical guidance.

Ther Adv Med Oncol 2015 Sep;7(5):291-6

Medical Oncology Department, Parc de Salut Mar, Cancer Research Program, Hospital del Mar Medical Research Institute, Passeig Maritim 25, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1177/1758834015598536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543856PMC
September 2015

Genetic analysis of high bone mass cases from the BARCOS cohort of Spanish postmenopausal women.

PLoS One 2014 15;9(4):e94607. Epub 2014 Apr 15.

Departament de Genètica, Universitat de Barcelona, IBUB, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Barcelona, Spain; Institut de Biomedicina Universitat de Barcelona (IBUB), Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094607PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988071PMC
January 2015

Analyses of RANK and RANKL in the post-GWAS context: functional evidence of vitamin D stimulation through a RANKL distal region.

J Bone Miner Res 2013 Dec;28(12):2550-60

URFOA, IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF), Barcelona, Spain.

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http://dx.doi.org/10.1002/jbmr.2001DOI Listing
December 2013

Genetic determinants of aromatase inhibitor-related arthralgia: the B-ABLE cohort study.

Breast Cancer Res Treat 2013 Jul 19;140(2):385-95. Epub 2013 Jul 19.

URFOA-IMIM Department, Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF), Instituto de Salud Carlos III FEDER, Parc de Salut Mar, C/Dr Aiguader, 88, 2nd Floor, 08003, Barcelona, Spain.

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http://dx.doi.org/10.1007/s10549-013-2638-3DOI Listing
July 2013

Assessment of gene-by-sex interaction effect on bone mineral density.

J Bone Miner Res 2012 Oct;27(10):2051-64

Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue CT3, Boston,MA 02118, USA.

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http://dx.doi.org/10.1002/jbmr.1679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447125PMC
October 2012

Host serum is not indispensable in collagen performance in viable meniscal transplantation at 4-week incubation.

Knee Surg Sports Traumatol Arthrosc 2012 Sep 22;20(9):1681-8. Epub 2011 Oct 22.

Department of Orthopaedic Surgery, Hospital de Sant Pau, Universitat Autònoma de Barcelona, Sant Antoni María Claret, 167, 08025 Barcelona, Spain.

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http://dx.doi.org/10.1007/s00167-011-1722-7DOI Listing
September 2012

COL1A1 haplotypes and hip fracture.

J Bone Miner Res 2012 Apr;27(4):950-3

Departament de Genètica, Universitat de Barcelona, IBUB, Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Barcelona, Spain.

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http://dx.doi.org/10.1002/jbmr.1536DOI Listing
April 2012

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.

Authors:
Karol Estrada Unnur Styrkarsdottir Evangelos Evangelou Yi-Hsiang Hsu Emma L Duncan Evangelia E Ntzani Ling Oei Omar M E Albagha Najaf Amin John P Kemp Daniel L Koller Guo Li Ching-Ti Liu Ryan L Minster Alireza Moayyeri Liesbeth Vandenput Dana Willner Su-Mei Xiao Laura M Yerges-Armstrong Hou-Feng Zheng Nerea Alonso Joel Eriksson Candace M Kammerer Stephen K Kaptoge Paul J Leo Gudmar Thorleifsson Scott G Wilson James F Wilson Ville Aalto Markku Alen Aaron K Aragaki Thor Aspelund Jacqueline R Center Zoe Dailiana David J Duggan Melissa Garcia Natàlia Garcia-Giralt Sylvie Giroux Göran Hallmans Lynne J Hocking Lise Bjerre Husted Karen A Jameson Rita Khusainova Ghi Su Kim Charles Kooperberg Theodora Koromila Marcin Kruk Marika Laaksonen Andrea Z Lacroix Seung Hun Lee Ping C Leung Joshua R Lewis Laura Masi Simona Mencej-Bedrac Tuan V Nguyen Xavier Nogues Millan S Patel Janez Prezelj Lynda M Rose Serena Scollen Kristin Siggeirsdottir Albert V Smith Olle Svensson Stella Trompet Olivia Trummer Natasja M van Schoor Jean Woo Kun Zhu Susana Balcells Maria Luisa Brandi Brendan M Buckley Sulin Cheng Claus Christiansen Cyrus Cooper George Dedoussis Ian Ford Morten Frost David Goltzman Jesús González-Macías Mika Kähönen Magnus Karlsson Elza Khusnutdinova Jung-Min Koh Panagoula Kollia Bente Lomholt Langdahl William D Leslie Paul Lips Östen Ljunggren Roman S Lorenc Janja Marc Dan Mellström Barbara Obermayer-Pietsch José M Olmos Ulrika Pettersson-Kymmer David M Reid José A Riancho Paul M Ridker François Rousseau P Eline Slagboom Nelson L S Tang Roser Urreizti Wim Van Hul Jorma Viikari María T Zarrabeitia Yurii S Aulchenko Martha Castano-Betancourt Elin Grundberg Lizbeth Herrera Thorvaldur Ingvarsson Hrefna Johannsdottir Tony Kwan Rui Li Robert Luben Carolina Medina-Gómez Stefan Th Palsson Sjur Reppe Jerome I Rotter Gunnar Sigurdsson Joyce B J van Meurs Dominique Verlaan Frances M K Williams Andrew R Wood Yanhua Zhou Kaare M Gautvik Tomi Pastinen Soumya Raychaudhuri Jane A Cauley Daniel I Chasman Graeme R Clark Steven R Cummings Patrick Danoy Elaine M Dennison Richard Eastell John A Eisman Vilmundur Gudnason Albert Hofman Rebecca D Jackson Graeme Jones J Wouter Jukema Kay-Tee Khaw Terho Lehtimäki Yongmei Liu Mattias Lorentzon Eugene McCloskey Braxton D Mitchell Kannabiran Nandakumar Geoffrey C Nicholson Ben A Oostra Munro Peacock Huibert A P Pols Richard L Prince Olli Raitakari Ian R Reid John Robbins Philip N Sambrook Pak Chung Sham Alan R Shuldiner Frances A Tylavsky Cornelia M van Duijn Nick J Wareham L Adrienne Cupples Michael J Econs David M Evans Tamara B Harris Annie Wai Chee Kung Bruce M Psaty Jonathan Reeve Timothy D Spector Elizabeth A Streeten M Carola Zillikens Unnur Thorsteinsdottir Claes Ohlsson David Karasik J Brent Richards Matthew A Brown Kari Stefansson André G Uitterlinden Stuart H Ralston John P A Ioannidis Douglas P Kiel Fernando Rivadeneira

Nat Genet 2012 Apr 15;44(5):491-501. Epub 2012 Apr 15.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://kooperberg.fhcrc.org/papers/2012estrada.pdf
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http://www.nature.com/doifinder/10.1038/ng.2249
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http://dx.doi.org/10.1038/ng.2249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338864PMC
April 2012

In vivo evaluation of 3-dimensional polycaprolactone scaffolds for cartilage repair in rabbits.

Am J Sports Med 2010 Mar 21;38(3):509-19. Epub 2010 Jan 21.

Department of Traumatology and Orthopaedic Surgery, URFOA, IMIM, RETICEF, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1177/0363546509352448DOI Listing
March 2010

Reduced proliferation and osteocalcin expression in osteoblasts of male idiopathic osteoporosis.

Calcif Tissue Int 2010 Mar 26;86(3):220-6. Epub 2010 Jan 26.

Unitat de Recerca en Fisipatologia Ossia i Articular, Institut Municipal d'Investigació Mèdica, Hospital del Mar, Autonomous University of Barcelona, Dr. Aiguader 88, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1007/s00223-010-9336-5DOI Listing
March 2010

Cryopreservation does not alter the ultrastructure of the meniscus.

Knee Surg Sports Traumatol Arthrosc 2009 Jun 19;17(6):639-44. Epub 2009 Feb 19.

Department of Orthopaedic Surgery, URFOA-IMIM, Hospital Universitari del Mar, Universitat Autònoma de Barcelona, Passeig Marítim 25-29, 08003, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00167-009-0736-xDOI Listing
June 2009

Decreased metalloproteinase production as a response to mechanical pressure in human cartilage: a mechanism for homeostatic regulation.

Arthritis Res Ther 2006 ;8(5):R149

Unitat de recerca en fisiopatologia òssia i articular-Institut Municipal d'Investigació Mèdica, Hospital del Mar, Universitat Autònoma de Barcelona, Dr, Aiguader 80, 08003-Barcelona, Spain.

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http://dx.doi.org/10.1186/ar2042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779454PMC
February 2007

Haplotypes defined by promoter and intron 1 polymorphisms of the COLIA1 gene regulate bone mineral density in women.

J Clin Endocrinol Metab 2006 Sep 27;91(9):3575-83. Epub 2006 Jun 27.

Rheumatic Diseases Unit, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.

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http://dx.doi.org/10.1210/jc.2005-2651DOI Listing
September 2006

A new SNP in a negative regulatory region of the CYP19A1 gene is associated with lumbar spine BMD in postmenopausal women.

Bone 2006 May 15;38(5):738-43. Epub 2005 Dec 15.

URFOA-IMIM, Hospital del Mar, Universitat Autònoma de Barcelona, C/Passeig Maritim 25, E-08003 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bone.2005.10.010DOI Listing
May 2006

In vitro functional assay of alleles and haplotypes of two COL1A1-promoter SNPs.

Bone 2005 May 7;36(5):902-8. Epub 2005 Apr 7.

Department of Genetics, Universitat de Barcelona, Av. Diagonal 645, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bone.2004.12.012DOI Listing
May 2005

Regulation of CYP19 gene expression in primary human osteoblasts: effects of vitamin D and other treatments.

Eur J Endocrinol 2003 May;148(5):519-26

URFOA-IMIM, Hospital del Mar, Universitat Autonoma de Barcelona, C/Doctor Aiguader 80, E-08003 Barcelona, Spain.

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http://dx.doi.org/10.1530/eje.0.1480519DOI Listing
May 2003