Publications by authors named "Natacha Entz-Werle"

49Publications

Prognostic relevance of clinical and molecular risk factors in children with high-risk medulloblastoma treated in the phase 2 trial PNET HR+5.

Authors:
Christelle Dufour Stephanie Foulon Anne Geoffray Julien Masliah-Planchon Dominique Figarella-Branger Léa Guerrini-Rousseau Cecile Faure-Conter Celine Icher Anne-Isabelle Bertozzi Pierre Leblond Tasnime Akbaraly Franck Bourdeaut Nicolas André Celine Chappé Pascale Schneider Emilie De Carli Pascal Chastagner Claire Berger Julien Lejeune Christine Soler Natacha Entz-Werlé Marie-Bernadette Delisle

Neuro Oncol 2020 Dec 30. Epub 2020 Dec 30.

Departments of Pathology, Toulouse University Hospital, Toulouse III university, Toulouse, France.

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December 2020

Biological Relevance of RGD-Integrin Subtype-Specific Ligands in Cancer.

Authors:
Saidu Sani Mélissa Messe Quentin Fuchs Marina Pierrevelcin Patrice Laquerriere Natacha Entz-Werle Damien Reita Nelly Etienne-Selloum Véronique Bruban Laurence Choulier Sophie Martin Monique Dontenwill

Chembiochem 2020 Nov 3. Epub 2020 Nov 3.

Laboratoire de Bioimagerie et Pathologies (LBP), UMR CNRS 7021, Institut Thématique Interdisciplinaire InnoVec, Université de Strasbourg, Faculté de Pharmacie, 74 route du, Rhin, CS 60024, 67401, Illkirch Cedex, France.

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November 2020

SFCE-RAPIRI Phase I Study of Rapamycin Plus Irinotecan: A New Way to Target Intra-Tumor Hypoxia in Pediatric Refractory Cancers.

Authors:
Sarah Jannier Véronique Kemmel Consuelo Sebastia Sancho Agathe Chammas Amelia-Naomie Sabo Erwan Pencreach Françoise Farace Marie Pierre Chenard Benoit Lhermitte Birgit Geoerger Isabelle Aerts Didier Frappaz Pierre Leblond Nicolas André Stephane Ducassou Nadège Corradini Anne Isabelle Bertozzi Eric Guérin Florence Vincent Michel Velten Natacha Entz-Werle

Cancers (Basel) 2020 Oct 20;12(10). Epub 2020 Oct 20.

Pediatric Onco-Hematology Unit, University Hospital of Strasbourg, 67098 Strasbourg, France.

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October 2020

Focus on Hypoxia-Related Pathways in Pediatric Osteosarcomas and Their Druggability.

Authors:
Marina Pierrevelcin Quentin Fuchs Benoit Lhermitte Melissa Messé Eric Guérin Noelle Weingertner Sophie Martin Isabelle Lelong-Rebel Charlotte Nazon Monique Dontenwill Natacha Entz-Werlé

Cells 2020 08 31;9(9). Epub 2020 Aug 31.

Laboratory of Bioimaging and Pathologies, UMR CNRS 7021, 67405 Illkirch, France.

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August 2020

Long-term follow-up of children with risk organ-negative Langerhans cell histiocytosis after 2-chlorodeoxyadenosine treatment.

Authors:
Mohamed-Aziz Barkaoui Emma Queheille Nathalie Aladjidi Geneviève Plat Eric Jeziorski Despina Moshous Anne Lambilliotte Kamila Kebaili Hélène Pacquement Guy Leverger Ludovic Mansuy Natacha Entz-Werlé Damien Bodet Pascale Schneider Anne Pagnier Anne Lutun Marion Gillibert-Yvert Fréderic Millot Fabienne Toutain Yves Reguerre Caroline Thomas Abdelatif Tazi Jean-François Emile Jean Donadieu Sébastien Héritier

Br J Haematol 2020 Jul 22. Epub 2020 Jul 22.

French Reference Center for Langerhans Cell Histiocytosis, Trousseau Hospital, Paris, France.

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July 2020

Pheochromocytoma and Paraganglioma in Children and Adolescents: Experience of the French Society of Pediatric Oncology (SFCE).

Authors:
Marie de Tersant Lucile Généré Claire Freyçon Sophie Villebasse Rachid Abbas Anne Barlier Damien Bodet Nadège Corradini Anne-Sophie Defachelles Natacha Entz-Werle Cyrielle Fouquet Louise Galmiche Virginie Gandemer Brigitte Lacour Ludovic Mansuy Daniel Orbach Claire Pluchart Yves Réguerre Charlotte Rigaud Sabine Sarnacki Nicolas Sirvent Jean-Louis Stephan Estelle Thebaud Anne-Paule Gimenez-Roqueplo Laurence Brugières

J Endocr Soc 2020 May 3;4(5):bvaa039. Epub 2020 Apr 3.

Centre de Cancérologie Gustave Roussy, Département de Cancérologie de l'Enfant et de l'Adolescent, Paris-Saclay University Villejuif, France.

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May 2020

Hypoxia Inducible Factors' Signaling in Pediatric High-Grade Gliomas: Role, Modelization and Innovative Targeted Approaches.

Authors:
Quentin Fuchs Marina Pierrevelcin Melissa Messe Benoit Lhermitte Anne-Florence Blandin Christophe Papin Andres Coca Monique Dontenwill Natacha Entz-Werlé

Cancers (Basel) 2020 Apr 15;12(4). Epub 2020 Apr 15.

UMR CNRS 7021, Laboratory Bioimaging and Pathologies, Tumoral Signaling and Therapeutic Targets team, Faculty of Pharmacy, 74 route du Rhin, 67405 Illkirch, France.

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April 2020

Cabozantinib in patients with advanced Ewing sarcoma or osteosarcoma (CABONE): a multicentre, single-arm, phase 2 trial.

Authors:
Antoine Italiano Olivier Mir Simone Mathoulin-Pelissier Nicolas Penel Sophie Piperno-Neumann Emmanuelle Bompas Christine Chevreau Florence Duffaud Natacha Entz-Werlé Esma Saada Isabelle Ray-Coquard Cyril Lervat Nathalie Gaspar Perrine Marec-Berard Hélène Pacquement John Wright Maud Toulmonde Alban Bessede Amandine Crombe Michèle Kind Carine Bellera Jean-Yves Blay

Lancet Oncol 2020 03 17;21(3):446-455. Epub 2020 Feb 17.

Department of Medicine, Centre Leon Berard, Lyon, France.

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March 2020

Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric -Mutated Gliomas Recreate the Patient Tumor Complexity.

Authors:
Anne-Florence Blandin Aurélie Durand Marie Litzler Aurélien Tripp Éric Guérin Elisa Ruhland Adeline Obrecht Céline Keime Quentin Fuchs Damien Reita Benoit Lhermitte Andres Coca Chris Jones Isabelle Lelong Rebel Pascal Villa Izzie Jacques Namer Monique Dontenwill Dominique Guenot Natacha Entz-Werle

Cancers (Basel) 2019 Nov 26;11(12). Epub 2019 Nov 26.

UMR CNRS 7021, Laboratory Bioimaging and Pathologies, Tumoral Signaling and Therapeutic Targets, Faculty of Pharmacy, 74 route du Rhin, 67401 Illkirch, France.

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November 2019

Spinal cord atypical teratoid/rhabdoid tumors in children: Clinical, genetic, and outcome characteristics in a representative European cohort.

Authors:
Martin Benesch Karolina Nemes Petra Neumayer Martin Hasselblatt Beate Timmermann Brigitte Bison Georg Ebetsberger-Dachs Franck Bourdeaut Christelle Dufour Veronica Biassoni Andrés Morales La Madrid Natacha Entz-Werle Véronique Laithier Franz Quehenberger Serge Weis David Sumerauer Reiner Siebert Susanne Bens Reinhard Schneppenheim Marcel Kool Piergiorgio Modena Fanny Fouyssac Michael C Frühwald

Pediatr Blood Cancer 2020 01 1;67(1):e28022. Epub 2019 Oct 1.

Swabian Children's Cancer Center, University Children's Hospital, University Hospital Augsburg, Augsburg, Germany.

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January 2020

Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand?

Authors:
Fatma E El-Khouly Sophie E M Veldhuijzen van Zanten Vicente Santa-Maria Lopez N Harry Hendrikse Gertjan J L Kaspers G Loizos David Sumerauer Karsten Nysom Kaie Pruunsild Virve Pentikainen Halldora K Thorarinsdottir Giedre Rutkauskiene Victor Calvagna Monika Drogosiewicz Monica Dragomir Ladislav Deak Lidija Kitanovski Andre O von Bueren Rejin Kebudi Irene Slavc Sandra Jacobs Filip Jadrijevic-Cvrlje Natacha Entz-Werle Jacques Grill Antonis Kattamis Peter Hauser Jane Pears Veronica Biassoni Maura Massimino Enrique Lopez Aguilar Ingrid K Torsvik Maria Joao Gil-da-Costa Ella Kumirova Ofelia Cruz-Martinez Stefan Holm Simon Bailey Tim Hayden Ulrich W Thomale Geert O R Janssens Christof M Kramm Dannis G van Vuurden

J Neurooncol 2019 Oct 14;145(1):177-184. Epub 2019 Sep 14.

Pediatric Oncology, Emma Children's Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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October 2019

A 1-Year Prospective French Nationwide Study of Emergency Hospital Admissions in Children and Adults with Primary Immunodeficiency.

Authors:
Hélène Coignard-Biehler Nizar Mahlaoui Benoit Pilmis Vincent Barlogis Pauline Brosselin Nathalie De Vergnes Marianne Debré Marion Malphettes Pierre Frange Emilie Catherinot Isabelle Pellier Isabelle Durieu Antoinette Perlat Bruno Royer Alain Le Quellec Eric Jeziorski Alain Fischer Olivier Lortholary Laurent Aaron Daniel Adoue Claire Aguilar Nathalie Aladjidi Alexandre Alcais Zahir Amoura Philippe Arlet Corinne Armari-Alla Brigitte Bader-Meunier Sophie Bayart Yves Bertrand Boris Bienvenu Stéphane Blanche Damien Bodet Bernard Bonnotte Raphaël Borie Patrick Boutard Claire Briandet Jean-Paul Brion Jacques Brouard Sarah Cohen-Beaussant Laurence Costes Louis-Jean Couderc Pierre Cougoul Virginie Courteille Geneviève de Saint Basile Catherine Devoldere Anne Deville Jean Donadieu Eric Dore Fabienne Dulieu Christine Edan Natacha Entz-Werle Claire Fieschi Amandine Forestier Fanny Fouyssac Vincent Gajdos Lionel Galicier Virginie Gandemer Martine Gardembas Catherine Gaud Gaelle Guillerm Eric Hachulla Mohamed Hamidou Olivier Hermine Cyrille Hoarau Sébastien Humbert Arnaud Jaccard Serge Jacquot Jean-Philippe Jais Roland Jaussaud Pierre-Yves Jeandel Kamila Kebaili Anne-Sophie Korganow Olivier Lambotte Fanny Lanternier Claire Larroche Anne-Sophie Lascaux Emmanuelle Le Moigne Vincent Le Moing Yvon Lebranchu Marc Lecuit Guillaume Lefevre Richard Lemal Valérie Li Thiao Te Aude Marie-Cardine Nicolas Martin Silva Agathe Masseau Christian Massot Françoise Mazingue Etienne Merlin Gérard Michel Frédéric Millot Béatrice Monlibert Fabrice Monpoux Despina Moshous Luc Mouthon Martine Munzer Bénédicte Neven Raphaëlle Nove-Josserand Eric Oksenhendler Marie Ouachée-Chardin Caroline Oudot Anne Pagnier Jean-Louis Pasquali Marlène Pasquet Yves Perel Capucine Picard Christophe Piguet Dominique Plantaz Johan Provot Pierre Quartier Frédéric Rieux-Laucat Pascal Roblot Pierre-Marie Roger Pierre-Simon Rohrlich Hervé Rubie Valéry Salle Françoise Sarrot-Reynauld Amélie Servettaz Jean-Louis Stephan Nicolas Schleinitz Felipe Suarez Laure Swiader Sophie Taque Caroline Thomas Olivier Tournilhac Caroline Thumerelle François Tron Jean-Pierre Vannier Jean-François Viallard

J Clin Immunol 2019 10 10;39(7):702-712. Epub 2019 Aug 10.

Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker Pasteur, Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.

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October 2019

Denosumab for treating aneurysmal bone cysts in children.

Authors:
Sébastien Raux Amine Bouhamama Nathalie Gaspar Laurence Brugières Natacha Entz-Werlé Cindy Mallet Frédérique Dijoud François Gouin Perrine Marec-Bérard

Orthop Traumatol Surg Res 2019 10 26;105(6):1181-1185. Epub 2019 Jul 26.

IHOP, 1, place Professeur Joseph-Renaut, 69008 Lyon, France.

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October 2019

An integrated genomic and metabolomic approach for defining survival time in adult oligodendrogliomas patients.

Authors:
Caroline Bund Mariana Guergova-Kuras A Ercument Cicek François-Marie Moussallieh Nassim Dali-Youcef Martial Piotto Pilar Schneider Rémy Heller Natacha Entz-Werle Benoît Lhermitte Marie-Pierre Chenard Roland Schott François Proust Georges Noël Izzie Jacques Namer

Metabolomics 2019 04 29;15(5):69. Epub 2019 Apr 29.

Service de Biophysique et Médecine Nucléaire, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, 1, Avenue Molière, 67098, Strasbourg Cedex 09, France.

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April 2019

Association between genetic polymorphisms and platinum-induced ototoxicity in children.

Authors:
Gabrielle Lui Naïm Bouazza Françoise Denoyelle Marion Moine Laurence Brugières Pascal Chastagner Nadège Corradini Natacha Entz-Werle Cécile Vérité Judith Landmanparker Hélène Sudour-Bonnange Marlène Pasquet Arnauld Verschuur Cécile Faure-Conter François Doz Jean-Marc Tréluyer

Oncotarget 2018 Jul 20;9(56):30883-30893. Epub 2018 Jul 20.

University of Paris Descartes, EA 7323, Sorbonne Paris-Cité, France.

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July 2018

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

Authors:
Mara Vinci Anna Burford Valeria Molinari Ketty Kessler Sergey Popov Matthew Clarke Kathryn R Taylor Helen N Pemberton Christopher J Lord Alice Gutteridge Tim Forshew Diana Carvalho Lynley V Marshall Elizabeth Y Qin Wendy J Ingram Andrew S Moore Ho-Keung Ng Saoussen Trabelsi Dorra H'mida-Ben Brahim Natacha Entz-Werle Stergios Zacharoulis Sucheta Vaidya Henry C Mandeville Leslie R Bridges Andrew J Martin Safa Al-Sarraj Christopher Chandler Mariona Sunol Jaume Mora Carmen de Torres Ofelia Cruz Angel M Carcaboso Michelle Monje Alan Mackay Chris Jones

Nat Med 2018 08 2;24(8):1204-1215. Epub 2018 Jul 2.

Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.

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August 2018

A Pharmacokinetic and Pharmacogenetic Analysis of Osteosarcoma Patients Treated With High-Dose Methotrexate: Data From the OS2006/Sarcoma-09 Trial.

Authors:
Gabrielle Lui Jean-Marc Treluyer Brice Fresneau Sophie Piperno-Neumann Nathalie Gaspar Nadège Corradini Jean-Claude Gentet Perrine Marec Berard Valérie Laurence Pascale Schneider Natacha Entz-Werle Hélène Pacquement Frédéric Millot Sophie Taque Claire Freycon Cyril Lervat Marie Cécile Le Deley Céline Mahier Ait Oukhatar Laurence Brugieres Gwénaël Le Teuff Naïm Bouazza

J Clin Pharmacol 2018 12 23;58(12):1541-1549. Epub 2018 May 23.

EA 7323, Université Paris Descartes Sorbonne Paris Cité, Paris, France.

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December 2018

Results of methotrexate-etoposide-ifosfamide based regimen (M-EI) in osteosarcoma patients included in the French OS2006/sarcome-09 study.

Authors:
Nathalie Gaspar Bob-Valéry Occean Hélène Pacquement Emmanuelle Bompas Corine Bouvier Hervé J Brisse Marie-Pierre Castex Nadir Cheurfa Nadège Corradini Jessy Delaye Natacha Entz-Werlé Jean-Claude Gentet Antoine Italiano Cyril Lervat Perrine Marec-Berard Eric Mascard Françoise Redini Laure Saumet Claudine Schmitt Marie-Dominique Tabone Cécile Verite-Goulard Marie-Cécile Le Deley Sophie Piperno-Neumann Laurence Brugieres

Eur J Cancer 2018 01 28;88:57-66. Epub 2017 Nov 28.

Department of Oncology for Child and Adolescent, Gustave Roussy, Villejuif, France.

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January 2018

Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition.

Authors:
Aurélia Nguyen François Marie Moussallieh Alan Mackay A Ercument Cicek Andres Coca Marie Pierre Chenard Noelle Weingertner Benoit Lhermitte Eric Letouzé Eric Guérin Erwan Pencreach Sarah Jannier Dominique Guenot Izzie Jacques Namer Chris Jones Natacha Entz-Werlé

Oncotarget 2017 Sep 23;8(42):71597-71617. Epub 2017 Mar 23.

Laboratory EA 3430, Progression Tumorale et Micro-Environnement, Approches Translationnelles et Epidémiologie, University of Strasbourg, Strasbourg, France.

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September 2017

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.

Authors:
Alan Mackay Anna Burford Diana Carvalho Elisa Izquierdo Janat Fazal-Salom Kathryn R Taylor Lynn Bjerke Matthew Clarke Mara Vinci Meera Nandhabalan Sara Temelso Sergey Popov Valeria Molinari Pichai Raman Angela J Waanders Harry J Han Saumya Gupta Lynley Marshall Stergios Zacharoulis Sucheta Vaidya Henry C Mandeville Leslie R Bridges Andrew J Martin Safa Al-Sarraj Christopher Chandler Ho-Keung Ng Xingang Li Kun Mu Saoussen Trabelsi Dorra H'mida-Ben Brahim Alexei N Kisljakov Dmitry M Konovalov Andrew S Moore Angel Montero Carcaboso Mariona Sunol Carmen de Torres Ofelia Cruz Jaume Mora Ludmila I Shats João N Stavale Lucas T Bidinotto Rui M Reis Natacha Entz-Werle Michael Farrell Jane Cryan Darach Crimmins John Caird Jane Pears Michelle Monje Marie-Anne Debily David Castel Jacques Grill Cynthia Hawkins Hamid Nikbakht Nada Jabado Suzanne J Baker Stefan M Pfister David T W Jones Maryam Fouladi André O von Bueren Michael Baudis Adam Resnick Chris Jones

Cancer Cell 2017 10 28;32(4):520-537.e5. Epub 2017 Sep 28.

Division of Molecular Pathology, The Institute of Cancer Research, London, UK; Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK. Electronic address:

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October 2017