Nassima Oumata

Nassima Oumata

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Nassima Oumata

Nassima Oumata

Publications by authors named "Nassima Oumata"

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31Publications

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Recent advances in the development of cyclin-dependent kinase 7 inhibitors.

Eur J Med Chem 2019 Dec 22;183:111641. Epub 2019 Aug 22.

Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes UMR-S 1022 Inserm, 4 avenue de l'Observatoire, Paris, 75006, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.111641DOI Listing
December 2019

Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models.

Sci Rep 2019 04 30;9(1):6653. Epub 2019 Apr 30.

Inserm, Sorbonne Université, Centre de Recherche Saint-Antoine (CRSA), UMR_S 938, Institute of Cardiometabolism and Nutrition (ICAN), F-75012, Paris, France.

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http://dx.doi.org/10.1038/s41598-019-43111-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491434PMC
April 2019

A β-glucuronidase-responsive albumin-binding prodrug for potential selective kinase inhibitor-based cancer chemotherapy.

Eur J Med Chem 2018 Oct 3;158:1-6. Epub 2018 Sep 3.

Institut de Chimie des Milieux et des Matériaux de Poitiers (IC2MP), Université de Poitiers, CNRS, Groupe "Systèmes Moléculaires Programmés", 4 rue Michel Brunet, TSA 51106, F-86073, Poitiers, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234183077
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http://dx.doi.org/10.1016/j.ejmech.2018.08.100DOI Listing
October 2018

Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor.

Eur J Med Chem 2017 Jan 22;125:696-709. Epub 2016 Sep 22.

ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.09.064DOI Listing
January 2017

Natural product extracts of the Canadian prairie plant, Thermopsis rhombifolia, have anti-cancer activity in phenotypic cell-based assays.

Nat Prod Res 2015 25;29(11):1026-34. Epub 2014 Nov 25.

a Cancer Cell Laboratory, Department of Biological Sciences , University of Lethbridge , 4401 University Dr, Lethbridge , AB , Canada T1K 3M4.

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http://dx.doi.org/10.1080/14786419.2014.979423DOI Listing
July 2015

Antitumoral effects of cyclin-dependent kinases inhibitors CR8 and MR4 on chronic myeloid leukemia cell lines.

J Biomed Sci 2015 Jul 17;22:57. Epub 2015 Jul 17.

Laboratoire de Thérapie Cellulaire et Immunobiologie du Cancer, Université de Bretagne Occidentale, CHRU Morvan, 5 avenue Foch, 29609, Brest Cedex, France.

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http://dx.doi.org/10.1186/s12929-015-0163-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504225PMC
July 2015

Structure-activity relationship study around guanabenz identifies two derivatives retaining antiprion activity but having lost α2-adrenergic receptor agonistic activity.

ACS Chem Neurosci 2014 Oct 22;5(10):1075-82. Epub 2014 Sep 22.

Inserm UMR 1078, Université de Bretagne Occidentale , Faculté de Médecine et des Sciences de la Santé; Etablissement Français du Sang (EFS) Bretagne; CHRU Brest, Hôpital Morvan, Laboratoire de Génétique Moléculaire, 29200 Brest, France.

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http://dx.doi.org/10.1021/cn5001588DOI Listing
October 2014

Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles.

Eur J Med Chem 2014 Jul 3;82:363-71. Epub 2014 Jun 3.

Inserm UMR 1078, Université de Bretagne Occidentale, Faculté de Médecine et des Sciences de la Santé, Etablissement Français du Sang (EFS) Bretagne, CHRU Brest, Hôpital Morvan, Laboratoire de Génétique Moléculaire, Brest, France.

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http://dx.doi.org/10.1016/j.ejmech.2014.05.083DOI Listing
July 2014

Spectroscopic and DFT studies on 6-aminophenanthridine and its derivatives provide insights in their activity towards ribosomal RNA.

Biochimie 2014 Feb 30;97:194-9. Epub 2013 Oct 30.

Department of Cell and Molecular Biology, Uppsala University, Box-596, BMC, 75124 Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2013.10.012DOI Listing
February 2014

Cyclin-dependent kinase inhibitors closer to market launch?

Expert Opin Ther Pat 2013 Aug 22;23(8):945-63. Epub 2013 Apr 22.

Laboratoire de Chimie Organique 2, INSERM U 1022, Université Paris - Descartes, 4 avenue de l'Observatoire, 75270 Paris cedex 06, France.

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http://dx.doi.org/10.1517/13543776.2013.789861DOI Listing
August 2013

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action.

FASEB J 2012 Dec 12;26(12):5115-23. Epub 2012 Sep 12.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Ave., New York, NY 10021, USA.

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http://dx.doi.org/10.1096/fj.12-212985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509055PMC
December 2012

Use of ATP analogs to inhibit HIV-1 transcription.

Virology 2012 Oct 6;432(1):219-31. Epub 2012 Jul 6.

National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA 20110, USA.

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http://dx.doi.org/10.1016/j.virol.2012.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431923PMC
October 2012

Synthesis and biological evaluation of selective and potent cyclin-dependent kinase inhibitors.

Eur J Med Chem 2012 Oct 1;56:210-6. Epub 2012 Sep 1.

ManRos Therapeutics, Centre de Perharidy, Hôtel de recherche, 29680 Roscoff, France.

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http://dx.doi.org/10.1016/j.ejmech.2012.08.033DOI Listing
October 2012

Targeting low molecular weight cyclin E (LMW-E) in breast cancer.

Breast Cancer Res Treat 2012 Apr 22;132(2):575-88. Epub 2011 Jun 22.

Department of Experimental Radiation Oncology, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10549-011-1638-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855283PMC
April 2012

Cyclin-dependent kinase inhibitors: a survey of recent patent literature.

Expert Opin Ther Pat 2010 Mar;20(3):377-404

INSERM U648, Université Paris Descartes, 4 avenue de l'observatoire, 75006 Paris, France.

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http://dx.doi.org/10.1517/13543770903524284DOI Listing
March 2010

Synthesis of conjugates of 6-aminophenanthridine and guanabenz, two structurally unrelated prion inhibitors, for the determination of their cellular targets by affinity chromatography.

Bioconjug Chem 2010 Feb;21(2):279-88

Laboratoire de Chimie Organique 2, INSERM U648, Universite Paris-Descartes, 4 avenue de l'Observatoire, 75270 Paris cedex 06, France.

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http://dx.doi.org/10.1021/bc900314nDOI Listing
February 2010

Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.

J Med Chem 2008 Sep 13;51(17):5229-42. Epub 2008 Aug 13.

Laboratoire de Chimie Organique 2, INSERM U 648, Universite Paris-Descartes, 4 avenue de l'Observatoire, 75270 Paris cedex 06, France.

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http://dx.doi.org/10.1021/jm800109eDOI Listing
September 2008