Publications by authors named "Nassier Harfouch"

7 Publications

  • Page 1 of 1

Can obstructive urolithiasis be safely excluded on contrast CT? A retrospective analysis of contrast-enhanced and noncontrast CT.

Am J Emerg Med 2021 Mar 22;47:70-73. Epub 2021 Mar 22.

Staten Island University Hospital, Northwell Health, 475 Seaview Ave, Staten Island, NY 10305, USA.

Purpose: The aim of this study was to determine if contrast-enhanced CT can safely exclude obstructive urolithiasis in patients with flank plain. We performed a retrospective cohort analysis to compare the negative predictive values of contrast-enhanced and non-contrast CTs for the detection of obstructing urolithiasis.

Methods: Through report analysis, we identified all non-contrast and contrast-enhanced CT examinations of the abdomen and pelvis performed on adult patients in the emergency department at a single, multi-site academic medical institution in 2017 with an indication of flank pain. The prevalence of obstructive urolithiasis in each group was calculated. We subsequently analyzed 200 consecutive studies from each of these groups (reported negative for obstructive urolithiasis) for negative predictive value calculation. Follow up abdominal imaging within 7 days from original presentation was used as a reference standard for analysis.

Results: In the noncontrast group, 1 study out of 200 was false negative (negative predictive value = 99.5%). In the contrast-enhanced group, there were no false negatives (negative predictive value = 100%). The prevalence of obstructive urolithiasis was 44.0% (351/797) in the noncontrast group and 18.7% (86/459) in the contrast-enhanced group.

Conclusion: Our results suggest that contrast-enhanced CT can safely exclude obstructing ureteral calculi in the setting of acute flank pain. This finding is of clinical relevance given the inherent benefit of IV contrast in diagnosing abdominopelvic pathology.
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http://dx.doi.org/10.1016/j.ajem.2021.03.059DOI Listing
March 2021

MD and DO: Differing Medical Degrees and the Associated Perceptions.

Curr Probl Diagn Radiol 2020 Aug 26. Epub 2020 Aug 26.

Staten Island University Hospital (SIUH) Northwell Health, Staten Island, NY.

Purpose: To highlight perspectives about differing medical degrees and graduate medical education amongst current allopathic (MD) and osteopathic (DO) radiology residents.

Materials And Method: Two hundred sixty-eight radiology residents were interviewed using an approved Association of Program Coordinators in Radiology (APCR) survey designed to evaluate perceptions of allopathic and osteopathic radiology residents regarding type of medical degree and their career development. The surveys were kept anonymous with no identifiable information. Residents in their first through fourth years of training replied with an approximate equal distribution amongst the different years.

Results: Based on the 268 respondents, DOs' more so than MDs', reported that their degree type altered their medical careers (P < 0.0001) and that they were advised to not pursue a radiology residency based on degree type (P< 0.0001). In addition, a large majority of both DOs' and MDs' felt that residency selection is favored towards the allopathic degree (P= 0.0451).

Conclusion: This survey-based study does reveal perceived differences in the residency recruitment process based on degree type. Future discussions to bridge this perceived gap will be important, especially in light of the recent ACGME merger between the 2 educational pathways.
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http://dx.doi.org/10.1067/j.cpradiol.2020.08.004DOI Listing
August 2020

The Use of FDG PET Parametric Imaging in the Diagnosis of Olivopontocerebellar Atrophy.

Clin Nucl Med 2020 Sep;45(9):e419-e421

From the Staten Island University Hospital, Northwell Health, Staten Island, NY.

Olivopontocerebellar atrophy is a rare neurodegenerative syndrome associated with 2 distinct disorders: multiple system atrophy and spinocerebellar ataxia. We present a case involving a 66-year-old man with adult-onset progressing cerebellar signs reflective of a cerebellar syndrome with no significant family history and unremarkable genetic testing for spinocerebellar ataxia. This case was found to be most consistent with sporadic olivopontocerebellar atrophy, which falls under the multiple system atrophy category. This diagnosis can be made using F-FDG PET/CT scanning and with MRI in some cases. However, in this case, relatively new PET/CT quantification and parametric imaging software was used for analysis, CortexID Suite.
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http://dx.doi.org/10.1097/RLU.0000000000003180DOI Listing
September 2020

Utility of ultrasound after a negative CT abdomen and pelvis in the emergency department.

Clin Imaging 2020 Dec 12;68:29-35. Epub 2020 Jun 12.

Staten Island University Hospital, Northwell Health, 475 Seaview Ave, Staten Island, NY 10305, USA.

Purpose: The purpose of this study is to assess the utility of an abdominal and/or pelvic ultrasound (US) performed within 24 h after a negative CT of the abdomen and pelvis (CTAP) in the emergency department (ED). The secondary endpoint is to assess whether there is a significant increase in length of stay (LOS) in the ED due to immediate US reimaging.

Method: We reviewed the imaging reports of 335 patients over the course of 3 years in our ED who had an US within 24 h after a negative CTAP. We then assessed type of US and whether the US showed any acute findings. We also evaluated LOS in the ED.

Results: Out of 335 patients, there were only three US cases suspicious for acute surgical pathology (3/335 or 0.9%). On 30-day clinical follow-up, only one of the three cases was confirmed as cholecystitis on pathology. The most common non-surgical findings on US not initially reported on CTAP were ovarian cysts (29/83) and gallstones (9/83). Additionally, the LOS for patients who received both a CTAP and US was 119 min longer than patients who only received a CTAP.

Conclusion: US abdomen and/or pelvis reimaging within 24 h following a negative CTAP is unlikely to change surgical management in the acute setting. US reimaging can still be useful in diagnosing non-surgical pathology, which could serve to explain the patient's pain. US reimaging after negative CTAP is associated with an average increase in the ED LOS.
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http://dx.doi.org/10.1016/j.clinimag.2020.06.007DOI Listing
December 2020

Robotic-assisted revision of gastrojejunostomy for gastrogastric fistula takedown after gastric bypass: a video case report.

Surg Obes Relat Dis 2016 Dec 21;12(10):1899. Epub 2016 Aug 21.

Tampa General Hospital in conjunction with University of South Florida Health, Tampa, Florida. Electronic address:

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http://dx.doi.org/10.1016/j.soard.2016.08.012DOI Listing
December 2016

Arrhythmogenic Right Ventricular Cardiomyopathy Caused by a Novel Frameshift Mutation.

Card Electrophysiol Clin 2016 Mar 16;8(1):217-21. Epub 2016 Jan 16.

Division of Cardiology, Department of Medicine, University of California San Francisco Medical Center, San Francisco, CA, USA.

Arrhythmogenic right ventricular cardiomyopathy is a rare cardiomyopathy that might be asymptomatic or symptomatic, causing palpations or syncope, and might lead to sudden cardiac death. It is recommended that physical exertion be reduced. It is also recommended that those with syncope and ventricular tachycardia/ventricular fibrillation have an implantable cardioverter-defibrillator placed. β-Blockers, antiarrhythmic drugs, and radiofrequency ablation should be used to control the ventricular arrhythmia burden in arrhythmogenic right ventricular cardiomyopathy.
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http://dx.doi.org/10.1016/j.ccep.2015.10.033DOI Listing
March 2016

Solid-phase synthesis of γ-AApeptides using a submonomeric approach.

Org Lett 2012 Jul 25;14(13):3446-9. Epub 2012 Jun 25.

Department of Chemistry, University of South Florida, Tampa, Florida 33620, USA.

The solid-phase synthesis of γ-AApeptides using a novel submonomeric approach that utilizes an allyl protection is reported. The strategy successfully circumvents the necessity of preparing γ-AApeptide building blocks in order to prepare γ-AApeptide sequences. This method will maximize the potential of developing chemically diverse γ-AApeptide libraries and thereby facilitate the biological applications of γ-AApeptides in the future.
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http://dx.doi.org/10.1021/ol301406aDOI Listing
July 2012