Publications by authors named "Naphtali Savion"

43Publications

-Allylmercapro--Acetylcysteine Attenuates the Oxidation-Induced Lens Opacification and Retinal Pigment Epithelial Cell Death In Vitro.

Authors:
Naphtali Savion Samia Dahamshi Milana Morein Shlomo Kotev-Emeth

Antioxidants (Basel) 2019 Jan 16;8(1). Epub 2019 Jan 16.

Goldschleger Eye Research Institute and Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv 61390, Israel.

View Article and Find Full Text PDF
January 2019

S-allylmercapto-N-acetylcysteine protects against oxidative stress and extends lifespan in Caenorhabditis elegans.

Authors:
Naphtali Savion Amir Levine Shlomo Kotev-Emeth Ulrike Bening Abu-Shach Limor Broday

PLoS One 2018 26;13(3):e0194780. Epub 2018 Mar 26.

Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.

View Article and Find Full Text PDF
July 2018

Role of heterotrimeric G proteins in platelet activation and clot formation in platelets treated with integrin αIIbβ3 inhibitor.

Authors:
Ivan Budnik Boris Shenkman Hagit Hauschner Isaac Zilinsky Naphtali Savion

Platelets 2018 May 13;29(3):265-269. Epub 2017 Apr 13.

e Goldschleger Eye Research Institute, Sackler Faculty of Medicine , Tel-Aviv University , Tel-Aviv , Israel.

View Article and Find Full Text PDF
May 2018

Cetuximab intensifies cisplatin-induced testicular toxicity.

Authors:
Mattan Levi Aron Popovtzer Moran Tzabari Aviram Mizrachi Naphtali Savion Salomon M Stemmer Ruth Shalgi Irit Ben-Aharon

Reprod Biomed Online 2016 Jul 20;33(1):102-10. Epub 2016 Apr 20.

Institute of Oncology, Davidoff Center, Rabin Medical Center, Beilinson Campus, Petah-Tiqva, and Sackler Faculty of Medicine, Tel-Aviv University, Israel. Electronic address:

View Article and Find Full Text PDF
July 2016

Local Application of Leptin Antagonist Attenuates Angiotensin II-Induced Ascending Aortic Aneurysm and Cardiac Remodeling.

Authors:
Danny Ben-Zvi Naphtali Savion Frank Kolodgie Amos Simon Sudeshna Fisch Katrin Schäfer Noa Bachner-Hinenzon Xin Cao Arieh Gertler Gili Solomon Erez Kachel Ehud Raanani Jacob Lavee Shlomo Kotev Emeth Renu Virmani Frederick J Schoen Jacob Schneiderman

J Am Heart Assoc 2016 05 3;5(5). Epub 2016 May 3.

The Gottesdiener Vascular Biology Laboratory, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Department of Vascular Surgery, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Vascular Surgery Research Laboratory, Department of Vascular and Endovascular Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

View Article and Find Full Text PDF
May 2016

Role of G protein signaling in the formation of the fibrin(ogen)-integrin αIIbβ3-actin cytoskeleton complex in platelets.

Authors:
Ivan Budnik Boris Shenkman Naphtali Savion

Platelets 2016 Sep 30;27(6):563-75. Epub 2016 Mar 30.

a Goldschleger Eye Research Institute and the Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine , Tel Aviv University , Tel Aviv , Israel.

View Article and Find Full Text PDF
September 2016

Dexrazoxane exacerbates doxorubicin-induced testicular toxicity.

Authors:
Mattan Levi Moran Tzabari Naphtali Savion Salomon M Stemmer Ruth Shalgi Irit Ben-Aharon

Reproduction 2015 Oct;150(4):357-66

Department of Cell and Developmental BiologySackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, IsraelThe Goldschleger Eye Research InstituteSheba Medical Center, Tel Hashomer 52621, IsraelInstitute of OncologyDavidoff Center, Rabin Medical Center, Beilinson Campus, 39 Jabotinski Street, Petah-Tiqva 49100, IsraelSackler Faculty of MedicineTel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel Department of Cell and Developmental BiologySackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, IsraelThe Goldschleger Eye Research InstituteSheba Medical Center, Tel Hashomer 52621, IsraelInstitute of OncologyDavidoff Center, Rabin Medical Center, Beilinson Campus, 39 Jabotinski Street, Petah-Tiqva 49100, IsraelSackler Faculty of MedicineTel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel

View Article and Find Full Text PDF
October 2015

Synergistic effect of signaling from receptors of soluble platelet agonists and outside-in signaling in formation of a stable fibrinogen-integrin αIIbβ3-actin cytoskeleton complex.

Authors:
Ivan Budnik Boris Shenkman Naphtali Savion

Thromb Res 2015 Jan 14;135(1):114-20. Epub 2014 Oct 14.

Goldschleger Eye Research Institute, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

View Article and Find Full Text PDF
January 2015

S-Allylmercapto-N-acetylcysteine (ASSNAC) protects cultured nerve cells from oxidative stress and attenuates experimental autoimmune encephalomyelitis.

Authors:
Naphtali Savion Nira Izigov Milana Morein Sarah Pri-Chen Shlomo Kotev-Emeth

Neurosci Lett 2014 Nov 26;583:108-13. Epub 2014 Sep 26.

Goldschleger Eye Research Institute, Sackler Faculty of Medicine, Tel Aviv University, Sheba Medical Center, Tel Hashomer 52621, Israel.

View Article and Find Full Text PDF
November 2014

Long-term renin-angiotensin blocking therapy in hypertensive patients with normal aorta may attenuate the formation of abdominal aortic aneurysms.

Authors:
Daniel Silverberg Anan Younis Naphtali Savion Gil Harari Dmitry Yakubovitch Basheer Sheick Yousif Moshe Halak Ehud Grossman Jacob Schneiderman

J Am Soc Hypertens 2014 Aug 18;8(8):571-7. Epub 2014 Apr 18.

The Department of Vascular Surgery, Sheba Medical Center, Tel Hashomer, Israel; The Gottesdiener Vascular Biology Laboratory, Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, Israel. Electronic address:

View Article and Find Full Text PDF
August 2014

Doxorubicin-induced vascular toxicity--targeting potential pathways may reduce procoagulant activity.

Authors:
Irit Ben Aharon Hadas Bar Joseph Moran Tzabari Boris Shenkman Nahid Farzam Mattan Levi Ruth Shalgi Salomon M Stemmer Naphtali Savion

PLoS One 2013 20;8(9):e75157. Epub 2013 Sep 20.

Institute of Oncology, Davidoff Center and Rabin Medical Center, Petah-Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

View Article and Find Full Text PDF
May 2014

Leptin locally synthesized in carotid atherosclerotic plaques could be associated with lesion instability and cerebral emboli.

Authors:
Jacob Schneiderman Katrin Schaefer Frank D Kolodgie Naphtali Savion Shlomo Kotev-Emeth Rima Dardik Amos J Simon Moshe Halak Clara Pariente Isaac Engelberg Stavros Konstantinides Renu Virmani

J Am Heart Assoc 2012 Oct 25;1(5):e001727. Epub 2012 Oct 25.

Department of Vascular Surgery and the Gottesdiener Vascular Biology Laboratory, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.

View Article and Find Full Text PDF
October 2012

Locally applied leptin induces regional aortic wall degeneration preceding aneurysm formation in apolipoprotein E-deficient mice.

Authors:
Ming Tao Peng Yu Binh T Nguyen Boaz Mizrahi Naphtali Savion Frank D Kolodgie Renu Virmani Shuai Hao C Keith Ozaki Jacob Schneiderman

Arterioscler Thromb Vasc Biol 2013 Feb 6;33(2):311-20. Epub 2012 Dec 6.

Division of Vascular and Endovascular Surgery, Brigham and Women’s Hospital/Harvard Medical School, Boston, MA, USA.

View Article and Find Full Text PDF
February 2013

Platelets selectively enhance lymphocyte adhesion on subendothelial matrix under arterial flow conditions.

Authors:
Galia Spectre Linjing Zhu Maria Ersoy Paul Hjemdahl Naphtali Savion David Varon Nailin Li

Thromb Haemost 2012 Aug 12;108(2):328-37. Epub 2012 Jun 12.

Department of Medicine-Solna, Clinical Pharmacology Unit, Karolinska Institute, Karolinska University Hospital-Solna, Stockholm, Sweden.

View Article and Find Full Text PDF
August 2012

Coating conditions matter to collagen matrix formation regarding von Willebrand factor and platelet binding.

Authors:
Shlomit Mendelboum Raviv Katalin Szekeres-Csiki Attila Jenei Janos Nagy Boris Shenkman Naphtali Savion Jolan Harsfalvi

Thromb Res 2012 Apr 5;129(4):e29-35. Epub 2011 Nov 5.

Clinical Research Center, Medical and Health Science Center, University Debrecen, Hungary.

View Article and Find Full Text PDF
April 2012

Brachial artery endothelial function predicts platelet function in control subjects and in patients with acute myocardial infarction.

Authors:
Michael Shechter Alon Shechter Hanoch Hod Paul Fefer Boris Shenkman Nira Koren-Morag Micha S Feinberg Dror Harats Ben Ami Sela Naphtali Savion David Varon Shlomi Matetzky

Platelets 2012 9;23(3):202-10. Epub 2011 Aug 9.

Leviev Heart Center, Chaim Sheba Medical Center, Tel Hashomer, Israel.

View Article and Find Full Text PDF
August 2012

S-allylmercapto-N-acetylcysteine up-regulates cellular glutathione and protects vascular endothelial cells from oxidative stress.

Authors:
Nira Izigov Nahid Farzam Naphtali Savion

Free Radic Biol Med 2011 May 31;50(9):1131-9. Epub 2011 Jan 31.

Goldschleger Eye Research Institute, Tel Hashomer 52621, Israel.

View Article and Find Full Text PDF
May 2011

Statins have an early antiplatelet effect in patients with acute myocardial infarction.

Authors:
Shlomi Matetzky Paul Fefer Boris Shenkman Michael Shechter Ilia Novikov Naphtali Savion David Varon Hanoch Hod

Platelets 2011 21;22(2):103-10. Epub 2010 Dec 21.

Heart Institute, Sheba Medical Center, Tel Hashomer, Israel.

View Article and Find Full Text PDF
May 2011

Visible light induces nitric oxide (NO) formation in sperm and endothelial cells.

Authors:
Rinat Ankri Harry Friedman Naphtali Savion Shlomo Kotev-Emeth Haim Breitbart Rachel Lubart

Lasers Surg Med 2010 Apr;42(4):348-52

Department of Physics, Bar Ilan University, Ramat Gan 52900, Israel.

View Article and Find Full Text PDF
April 2010

Allicin and disulfiram enhance platelet integrin alphaIIbbeta3-fibrinogen binding.

Authors:
Yoav Manaster Boris Shenkman Nurit Rosenberg Naphtali Savion

Thromb Res 2009 Sep 26;124(4):477-82. Epub 2009 Jul 26.

Goldschleger Eye Research Institute and Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Israel.

View Article and Find Full Text PDF
September 2009

Allicin up-regulates cellular glutathione level in vascular endothelial cells.

Authors:
Limor Horev-Azaria Shlomit Eliav Nira Izigov Sarah Pri-Chen David Mirelman Talia Miron Aharon Rabinkov Meir Wilchek Jasmine Jacob-Hirsch Ninette Amariglio Naphtali Savion

Eur J Nutr 2009 Mar 1;48(2):67-74. Epub 2008 Dec 1.

Goldschleger Eye Research Institute, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

View Article and Find Full Text PDF
March 2009

Phacoemulsification-induced injury in corneal endothelial cells mediated by apoptosis: in vitro model.

Authors:
Noa Geffen Moris Topaz Lilly Kredy-Farhan Irina S Barequet Nahid Farzam Ehud I Assia Naphtali Savion

J Cataract Refract Surg 2008 Dec;34(12):2146-52

Department of Ophthalmology, Meir Medical Center, Kfar-Saba, Israel.

View Article and Find Full Text PDF
December 2008

Effectiveness of reloading to overcome clopidogrel nonresponsiveness in patients with acute myocardial infarction.

Authors:
Shlomi Matetzky Paul Fefer Boris Shenkman David Varon Naphtali Savion Hanoch Hod

Am J Cardiol 2008 Sep 12;102(5):524-9. Epub 2008 Jun 12.

Heart Institute, Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

View Article and Find Full Text PDF
September 2008

Variable responsiveness to clopidogrel and aspirin among patients with acute coronary syndrome as assessed by platelet function tests.

Authors:
Boris Shenkman Shlomi Matetzky Paul Fefer Hanoch Hod Yulia Einav Aharon Lubetsky David Varon Naphtali Savion

Thromb Res 2008 26;122(3):336-45. Epub 2007 Dec 26.

Amalia Biron Research Institute of Thrombosis and Hemostasis, Israel.

View Article and Find Full Text PDF
October 2008

Involvement of cortactin and phosphotyrosine proteins in cell-cell contact formation in cultured bovine corneal endothelial cells.

Authors:
Lily Kredy-Farhan Shlomo Kotev-Emeth Naphtali Savion

Histochem Cell Biol 2008 Feb 14;129(2):193-202. Epub 2007 Nov 14.

Goldschleger Eye Research Institute and the Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

View Article and Find Full Text PDF
February 2008

CD4+ lymphocytes require platelets for adhesion to immobilized fibronectin in flow: role of beta(1) (CD29)-, beta(2) (CD18)-related integrins and non-integrin receptors.

Authors:
Boris Shenkman Grigory Brill Alexey Solpov Yuri Vitkovsky Boris Kuznik Alexander Koltakov Shlomo Kotev-Emeth Naphtali Savion Ilan Bank

Cell Immunol 2006 Jul 7;242(1):52-9. Epub 2006 Nov 7.

Institute of Thrombosis and Haemostasis, Sheba Medical Center, Tel-Hashomer, Israel.

View Article and Find Full Text PDF
July 2006

Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.

Authors:
Yael Porat Svetlana Porozov Danny Belkin Daphna Shimoni Yehudit Fisher Adina Belleli David Czeiger William F Silverman Michael Belkin Alexander Battler Valentin Fulga Naphtali Savion

Br J Haematol 2006 Dec;135(5):703-14

TheraVitae Ltd, Ness Ziona, Israel.

View Article and Find Full Text PDF
December 2006

ADAMTS-13 regulates platelet adhesion under flow. A new method for differentiation between inherited and acquired thrombotic thrombocytopenic purpura.

Authors:
Boris Shenkman Ulrich Budde Dorothea Angerhaus Aharon Lubetsky Naphtali Savion Uri Seligsohn David Varon

Thromb Haemost 2006 Aug;96(2):160-6

Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel-Hashomer 52621, Israel.

View Article and Find Full Text PDF
August 2006

Impact--the cone and plate(let) analyzer: testing platelet function and anti-platelet drug response.

Authors:
Naphtali Savion David Varon

Pathophysiol Haemost Thromb 2006 ;35(1-2):83-8

Goldschleger Eye Research Institute, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

View Article and Find Full Text PDF
September 2006

Platelets enhance CD4+ lymphocyte adhesion to extracellular matrix under flow conditions: role of platelet aggregation, integrins, and non-integrin receptors.

Authors:
Alexey Solpov Boris Shenkman Yuri Vitkovsky Grigory Brill Alexander Koltakov Nahid Farzam David Varon Ilan Bank Naphtali Savion

Thromb Haemost 2006 May;95(5):815-21

Department of Physiology, Chita Medical Academy, Chita, Russia.

View Article and Find Full Text PDF
May 2006

Increased platelet deposition on extracellular matrix under flow conditions in patients with antiphospholipid syndrome who experience thrombotic events.

Authors:
Yair Levy Boris Shenkman Ilia Tamarin Rachel Pauzner Yehuda Shoenfeld Pnina Langevitz Naphtali Savion David Varon

Arthritis Rheum 2005 Dec;52(12):4011-7

Meir Medical Center, Kfar Saba, Israel.

View Article and Find Full Text PDF
December 2005

A new point-of-care method for monitoring anti-platelet therapy: application of the cone and plate(let) analyzer.

Authors:
Galia Spectre Alexander Brill Alexander Gural Boris Shenkman Natalia Touretsky Elinor Mosseri Naphtali Savion David Varon

Platelets 2005 Aug;16(5):293-9

Coagulation Unit, Hematology Department, Hadassah Hebrew University Medical Center, Jerusalem, Israel.

View Article and Find Full Text PDF
August 2005

Ex vivo evaluation of erythrocytosis-enhanced platelet thrombus formation using the cone and plate(let) analyzer: effect of platelet antagonists.

Authors:
Ellinor I B Peerschke Richard T Silver Babette Weksler Sage E Grigg Naphtali Savion David Varon

Br J Haematol 2004 Oct;127(2):195-203

Department of Pathology, Weill Medical College of Cornell University, New York, NY, USA.

View Article and Find Full Text PDF
October 2004

Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction.

Authors:
Shlomi Matetzky Boris Shenkman Victor Guetta Michael Shechter Roy Beinart Roy Bienart Ilan Goldenberg Ilya Novikov Hanna Pres Naphtali Savion David Varon Hanoch Hod

Circulation 2004 Jun 7;109(25):3171-5. Epub 2004 Jun 7.

Heart Institute, Sheba Medical Center, Tel Hashomer, Israel.

View Article and Find Full Text PDF
June 2004

Platelet-leukocyte aggregation under shear stress: differential involvement of selectins and integrins.

Authors:
Hu Hu David Varon Paul Hjemdahl Naphtali Savion Sam Schulman Nailin Li

Thromb Haemost 2003 Oct;90(4):679-87

Department of Medicine, Division of Clinical Pharmacology, Karolinska Hospital, Stockholm, Sweden.

View Article and Find Full Text PDF
October 2003

Thrombospondin-1 mediates platelet adhesion at high shear via glycoprotein Ib (GPIb): an alternative/backup mechanism to von Willebrand factor.

Authors:
Kerstin Jurk Kenneth J Clemetson Philip G de Groot Martin F Brodde Michael Steiner Naphtali Savion David Varon Jan J Sixma Hugo Van Aken Beate E Kehrel

FASEB J 2003 Aug 17;17(11):1490-2. Epub 2003 Jun 17.

Department of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University-Hospital Münster, Mendelstr. 11, 48149 Münster, Germany.

View Article and Find Full Text PDF
August 2003

Establishment of a rat long-term culture expressing the osteogenic phenotype: dependence on dexamethasone and FGF-2.

Authors:
Shlomo Kotev-Emeth Sandu Pitaru Sara Pri-Chen Naphtali Savion

Connect Tissue Res 2002 ;43(4):606-12

Maurice and Gabriela Goldschleger Eye Research Institute, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

View Article and Find Full Text PDF
July 2003

Dalteparin sodium (fragmin) administration following acute infarction does not affect myocardial perfusion and function in swine.

Authors:
Mickey Scheinowitz Yuval Heled Pierre Chouraqui Zvi Vered Yfat Hayardeni Arkady Kotlyar David Castel Shy Livschitz Vivian Barak Naphtali Savion Michael Eldar

Cardiovasc Drugs Ther 2002 Jul;16(4):303-9

The Neufeld Cardiac Research Institute, Sheba Medical Center, Tel-Hashomer 52621, Israel.

View Article and Find Full Text PDF
July 2002

Diagnosis of thrombotic thrombocytopenic purpura based on modulation by patient plasma of normal platelet adhesion under flow condition.

Authors:
Boris Shenkman Aida Inbal Ilia Tamarin Aharon Lubetsky Naphtali Savion David Varon

Br J Haematol 2003 Feb;120(4):597-604

Institute of Thrombosis and Haemostasis, Sheba Medical Centre, Tel-Hashomer, Israel.

View Article and Find Full Text PDF
February 2003

Flow conditions modulate homocysteine induced changes in the expression of endothelial cell genes associated with cell-cell interaction and cytoskeletal rearrangement.

Authors:
Rima Dardik Naphtali Savion Nurit Gal David Varon

Thromb Haemost 2002 Dec;88(6):1047-53

Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel Hashomer, Israel.

View Article and Find Full Text PDF
December 2002

Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion.

Authors:
Xinkang Wang Robert T Dorsam Adam Lauver Hugh Wang Frank A Barbera Sandra Gibbs David Varon Naphtali Savion Steven M Friedman Giora Z Feuerstein

J Pharmacol Exp Ther 2002 Dec;303(3):1114-20

Department of Cardiovascular Sciences, Bristol-Myers Squibb Company, Experimental Station, Wilmington, Delaware 19880-0400, USA.

View Article and Find Full Text PDF
December 2002

Role of agr (RNAIII) in Staphylococcus aureus adherence to fibrinogen, fibronectin, platelets and endothelial cells under static and flow conditions.

Authors:
Boris Shenkman David Varon Ilia Tamarin Rima Dardik Martha Peisachov Naphtali Savion Ethan Rubinstein

J Med Microbiol 2002 Sep;51(9):747-754

Institute of Thrombosis and Hemostasis, *Infectious Diseases Unit, Sheba Medical Center, Tel Hashomer and †Goldschleger Eye Research Institute, Tel Aviv University, Tel Aviv, Israel.

View Article and Find Full Text PDF
September 2002

Venous shear stress enhances platelet mediated staphylococcal adhesion to artificial and damaged biological surfaces.

Authors:
Corina Fallgren Asa Ljungh Boris Shenkman David Varon Naphtali Savion

Biomaterials 2002 Dec;23(23):4581-9

Department of Medical Microbiology, Dermatology and Infection, University of Lund, Sweden.

View Article and Find Full Text PDF
December 2002