Publications by authors named "Naomasa Makita"

76Publications

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls.

Authors:
Roddy Walsh Najim Lahrouchi Rafik Tadros Florence Kyndt Charlotte Glinge Pieter G Postema Ahmad S Amin Eline A Nannenberg James S Ware Nicola Whiffin Francesco Mazzarotto Doris Škorić-Milosavljević Christian Krijger Elena Arbelo Dominique Babuty Hector Barajas-Martinez Britt M Beckmann Stéphane Bézieau J Martijn Bos Jeroen Breckpot Oscar Campuzano Silvia Castelletti Candan Celen Sebastian Clauss Anniek Corveleyn Lia Crotti Federica Dagradi Carlo de Asmundis Isabelle Denjoy Sven Dittmann Patrick T Ellinor Cristina Gil Ortuño Carla Giustetto Jean-Baptiste Gourraud Daisuke Hazeki Minoru Horie Taisuke Ishikawa Hideki Itoh Yoshiaki Kaneko Jørgen K Kanters Hiroki Kimoto Maria-Christina Kotta Ingrid P C Krapels Masahiko Kurabayashi Julieta Lazarte Antoine Leenhardt Bart L Loeys Catarina Lundin Takeru Makiyama Jacques Mansourati Raphaël P Martins Andrea Mazzanti Stellan Mörner Carlo Napolitano Kimie Ohkubo Michael Papadakis Boris Rudic Maria Sabater Molina Frédéric Sacher Hatice Sahin Georgia Sarquella-Brugada Regina Sebastiano Sanjay Sharma Mary N Sheppard Keiko Shimamoto M Benjamin Shoemaker Birgit Stallmeyer Johannes Steinfurt Yuji Tanaka David J Tester Keisuke Usuda Paul A van der Zwaag Sonia Van Dooren Lut Van Laer Annika Winbo Bo G Winkel Kenichiro Yamagata Sven Zumhagen Paul G A Volders Steven A Lubitz Charles Antzelevitch Pyotr G Platonov Katja E Odening Dan M Roden Jason D Roberts Jonathan R Skinner Jacob Tfelt-Hansen Maarten P van den Berg Morten S Olesen Pier D Lambiase Martin Borggrefe Kenshi Hayashi Annika Rydberg Tadashi Nakajima Masao Yoshinaga Johan B Saenen Stefan Kääb Pedro Brugada Tomas Robyns Daniela F Giachino Michael J Ackerman Ramon Brugada Josep Brugada Juan R Gimeno Can Hasdemir Pascale Guicheney Silvia G Priori Eric Schulze-Bahr Naomasa Makita Peter J Schwartz Wataru Shimizu Takeshi Aiba Jean-Jacques Schott Richard Redon Seiko Ohno Vincent Probst Elijah R Behr Julien Barc Connie R Bezzina

Genet Med 2020 Sep 7. Epub 2020 Sep 7.

Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41436-020-00946-5DOI Listing
September 2020

Dynamic QT response to cold-water face immersion in long-QT syndrome type 3.

Pediatr Int 2020 Aug 6;62(8):899-906. Epub 2020 Aug 6.

Department of Pediatric Cardiology, Okinawa Nanbu and Children's Medical Center, Okinawa, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ped.14319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496693PMC
August 2020

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome.

Authors:
Najim Lahrouchi Rafik Tadros Lia Crotti Yuka Mizusawa Pieter G Postema Leander Beekman Roddy Walsh Kanae Hasegawa Julien Barc Marko Ernsting Kari L Turkowski Andrea Mazzanti Britt M Beckmann Keiko Shimamoto Ulla-Britt Diamant Yanushi D Wijeyeratne Yu Kucho Tomas Robyns Taisuke Ishikawa Elena Arbelo Michael Christiansen Annika Winbo Reza Jabbari Steven A Lubitz Johannes Steinfurt Boris Rudic Bart Loeys M Ben Shoemaker Peter E Weeke Ryan Pfeiffer Brianna Davies Antoine Andorin Nynke Hofman Federica Dagradi Matteo Pedrazzini David J Tester J Martijn Bos Georgia Sarquella-Brugada Óscar Campuzano Pyotr G Platonov Birgit Stallmeyer Sven Zumhagen Eline A Nannenberg Jan H Veldink Leonard H van den Berg Ammar Al-Chalabi Christopher E Shaw Pamela J Shaw Karen E Morrison Peter M Andersen Martina Müller-Nurasyid Daniele Cusi Cristina Barlassina Pilar Galan Mark Lathrop Markus Munter Thomas Werge Marta Ribasés Tin Aung Chiea C Khor Mineo Ozaki Peter Lichtner Thomas Meitinger J Peter van Tintelen Yvonne Hoedemaekers Isabelle Denjoy Antoine Leenhardt Carlo Napolitano Wataru Shimizu Jean-Jacques Schott Jean-Baptiste Gourraud Takeru Makiyama Seiko Ohno Hideki Itoh Andrew D Krahn Charles Antzelevitch Dan M Roden Johan Saenen Martin Borggrefe Katja E Odening Patrick T Ellinor Jacob Tfelt-Hansen Jonathan R Skinner Maarten P van den Berg Morten Salling Olesen Josep Brugada Ramón Brugada Naomasa Makita Jeroen Breckpot Masao Yoshinaga Elijah R Behr Annika Rydberg Takeshi Aiba Stefan Kääb Silvia G Priori Pascale Guicheney Hanno L Tan Christopher Newton-Cheh Michael J Ackerman Peter J Schwartz Eric Schulze-Bahr Vincent Probst Minoru Horie Arthur A Wilde Michael W T Tanck Connie R Bezzina

Circulation 2020 Jul 20;142(4):324-338. Epub 2020 May 20.

Amsterdam UMC, University of Amsterdam, Heart Center; Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, The Netherlands (N.L., R.T., Y.M., P.G.P., L.B., R.W., N.H., H.L.T., A.A.W., C.R.B.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.120.045956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382531PMC
July 2020

Pathological Features of Lamin Cardiomyopathy.

Circ J 2020 Jun 25;84(7):1193. Epub 2020 Apr 25.

Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1253/circj.CJ-20-0187DOI Listing
June 2020

Identification of transmembrane protein 168 mutation in familial Brugada syndrome.

FASEB J 2020 May 16;34(5):6399-6417. Epub 2020 Mar 16.

Division of Molecular Medical Biochemistry, Department of Biochemistry and Molecular Biology, Shiga University of Medical Science, Otsu, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.201902991RDOI Listing
May 2020

Desmin-related myopathy characterized by non-compaction cardiomyopathy, cardiac conduction defect, and coronary artery dissection.

ESC Heart Fail 2020 Jun 6;7(3):1338-1343. Epub 2020 Mar 6.

Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ehf2.12667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261580PMC
June 2020

Gene Polymorphisms Are Associated With Occurrence of Tachycardia-Induced Cardiomyopathy in Patients With Atrial Fibrillation.

Circ Genom Precis Med 2018 07;11(7):e001980

Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan (Y.N., A.S., Y.O., T.T., C.M., H.M., S.T., M.A., N.H., S.O., Y.K.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGEN.117.001980DOI Listing
July 2018

HCN4 pacemaker channels attenuate the parasympathetic response and stabilize the spontaneous firing of the sinoatrial node.

J Physiol 2018 03 6;596(5):809-825. Epub 2018 Feb 6.

Department of Physiology, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1113/JP275303
Publisher Site
http://dx.doi.org/10.1113/JP275303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830425PMC
March 2018

Postmortem genetic analysis of sudden unexpected death in infancy: neonatal genetic screening may enable the prevention of sudden infant death.

J Hum Genet 2017 Nov 27;62(11):989-995. Epub 2017 Jul 27.

Division of Forensic Pathology and Science, Unit of Social Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University School of Medicine, Nagasaki, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jhg.2017.79DOI Listing
November 2017

A novel de novo calmodulin mutation in a 6-year-old boy who experienced an aborted cardiac arrest.

HeartRhythm Case Rep 2017 Jan 20;3(1):69-72. Epub 2016 Sep 20.

Department of Pediatric Cardiology, Okinawa Nanbu and Children's Medical Center, Okinawa, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrcr.2016.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420028PMC
January 2017

Genotype-Phenotype Correlation of Mutation for the Clinical and Electrocardiographic Characteristics of Probands With Brugada Syndrome: A Japanese Multicenter Registry.

Circulation 2017 Jun 24;135(23):2255-2270. Epub 2017 Mar 24.

From Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan (K.Y., T.A., K.K., S.K. S.Y., H.O., W.S.); Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Japan (M.H., S. Ohno); Department of Cardiovascular Medicine, University of Tokyo, Japan (K.Y.); Department of Cardiopulmonary Medicine, Keio University, Tokyo, Japan (S. Ogawa, K.F.); Division of Cardiology, Niigata University Graduate School of Medical and Dental Sciences, Japan (Y.A., H.W.); Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan (T.O., H.M.); Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Ishikawa, Japan (M.Y., K.H.); Molecular Physiology, Nagasaki University Graduate School of Biomedical Sciences, Japan (N.M.); Department of Cardiology, Tokyo Metropolitan Hiroo Hospital, Japan (H.S.); Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan (T.T.); Division of Cardiology, Yamaguchi University Graduate School of Medicine, Japan (A.S.); Department of Cardiology, Tokyo Women's Medical University, Japan (N.H.); Department of Cardiology, St Marianna University of Medicine, Kanagawa, Japan (R.K.); Department of Cardiovascular Medicine, Hiroshima University, Japan (Y.N.); Department of Cardiovascular Medicine, Osaka City University, Japan (M.T.); Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Japan (T.M.); Laboratory of Molecular Genetics, National Cerebral and Cardiovascular Center, Osaka, Japan (Y.M.); Departments of Cardiovascular Diseases, Pediatrics, and Molecular Pharmacology & Experimental Therapeutics; Divisions of Heart Rhythm Services and Pediatric Cardiology, Windland Smith Rice Sudden Death Genomics Laboratory, Mayo Clinic, Rochester, MN (J.D.K., M.J.A.); and Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan (W.S.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.117.027983DOI Listing
June 2017

Inherited bradyarrhythmia: A diverse genetic background.

J Arrhythm 2016 Oct 19;32(5):352-358. Epub 2015 Nov 19.

Department of Molecular Physiology, Nagasaki University Graduate School of Biomedical Sciences, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.joa.2015.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063261PMC
October 2016

Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I.

Int J Cardiol 2016 Mar 11;207:349-58. Epub 2016 Jan 11.

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1087, l'institut du thorax, Nantes, France; Centre National de la Recherche Scientifique (CNRS) UMR 6291, l'institut du thorax, Nantes, France; Université de Nantes, l'institut du thorax, Nantes, France; Centre Hospitalier Universitaire (CHU) de Nantes, l'institut du thorax, Service de Cardiologie, Nantes, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2016.01.052DOI Listing
March 2016

Molecular Mechanisms Underlying Urate-Induced Enhancement of Kv1.5 Channel Expression in HL-1 Atrial Myocytes.

Circ J 2015 16;79(12):2659-68. Epub 2015 Oct 16.

Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Institute of Regenerative Medicine and Biofunction, Tottori University Graduate School of Medical Science.

View Article

Download full-text PDF

Source
https://www.jstage.jst.go.jp/article/circj/79/12/79_CJ-15-04
Publisher Site
http://dx.doi.org/10.1253/circj.CJ-15-0416DOI Listing
September 2016

Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation.

Circ Arrhythm Electrophysiol 2015 Oct 30;8(5):1095-104. Epub 2015 Jun 30.

From the Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan (K.H., T.K., H.T., S.T., L.L., N.F., A.N., A.H., T.T., Y.T., M.K., M.Y.); Department of Cardiology, Komatsu Municipal Hospital, Komatsu, Japan (H.I.); and Department of Molecular Physiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan (N.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.114.002519DOI Listing
October 2015

Genotype-dependent differences in age of manifestation and arrhythmia complications in short QT syndrome.

Int J Cardiol 2015 15;190:393-402. Epub 2015 Apr 15.

Department of Molecular Physiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2015.04.090DOI Listing
February 2016

Novel mutation in the α-myosin heavy chain gene is associated with sick sinus syndrome.

Circ Arrhythm Electrophysiol 2015 Apr 25;8(2):400-8. Epub 2015 Feb 25.

From the Department of Molecular Physiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki (T.I., D.T.H., Y.T., N.M.); Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan (T.I., T.A., A.K.); Division of Pediatric Cardiology, University of Utah, Salt Lake City (C.J.J., C.B.A., S.M.B.); Cardiovascular Division, University of Tsukuba, Tsukuba (A.N.); Department of Heart Rhythm Management, Yokohama Rosai Hospital, Yokohama (A.N., S.K.); and Department of Veterinary Medicine, Kagoshima University, Kagoshima, Japan (T.A.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.114.002534DOI Listing
April 2015

Sodium channelopathy underlying familial sick sinus syndrome with early onset and predominantly male characteristics.

Circ Arrhythm Electrophysiol 2014 Jun 24;7(3):511-7. Epub 2014 Apr 24.

From the Departments of Molecular Physiology (K.A., T.M., D.T.H., T.I., Y.T., N.M.), Pediatrics (H.Y., H.M.), and Cardiovascular Medicine (S.F., M.K., K.M.), Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan; Departments of Pediatrics (N.S.) and Cardiovascular Medicine (K.O., I.W.), Nihon University Graduate School of Medicine, Tokyo, Japan; Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.M.); Division of Heart Rhythm Management, Yokohama Rosai Hospital, Yokohama, Japan (A.N.); and The Second Department of Internal Medicine (T.W., Y.O.) and Department of Heart Rhythm Management (H.A.), University of Occupational and Environmental Health, Kitakyushu, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.113.001340DOI Listing
June 2014

Right bundle branch block without overt heart disease predicts higher risk of pacemaker implantation: the study of atomic-bomb survivors.

Int J Cardiol 2014 Jun 28;174(1):77-82. Epub 2014 Mar 28.

Department of Clinical Studies, Radiation Effects Research Foundation, 1-8-6 Nakagawa, Nagasaki 850-0013, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2014.03.152DOI Listing
June 2014

Exon 3 deletion of RYR2 encoding cardiac ryanodine receptor is associated with left ventricular non-compaction.

Europace 2014 Nov 6;16(11):1646-54. Epub 2014 Jan 6.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Seta-Tsukinowa-cho, Otsu, Shiga 520-2192, Japan

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/eut382DOI Listing
November 2014

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.

Nat Genet 2013 Sep 21;45(9):1044-9. Epub 2013 Jul 21.

Department of Clinical and Experimental Cardiology, Heart Failure Research Center, Academic Medical Center, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869788PMC
September 2013

Successful control of life-threatening polymorphic ventricular tachycardia by radiofrequency catheter ablation in an infant.

Heart Vessels 2014 May 9;29(3):422-6. Epub 2013 Jul 9.

Department of Pediatrics and Child Health, Nihon University School of Medicine, 30-1 Oyaguchi Kamimachi, Itabashi-ku, Tokyo, 173-8610, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00380-013-0390-6DOI Listing
May 2014

Novel SCN3B mutation associated with brugada syndrome affects intracellular trafficking and function of Nav1.5.

Circ J 2013 21;77(4):959-67. Epub 2012 Dec 21.

Division of Genetic Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1253/circj.cj-12-0995DOI Listing
September 2013

Cardiac connexins, mutations and arrhythmias.

Curr Opin Cardiol 2012 May;27(3):236-41

The Leon H Charney Division of Cardiology, New York University School of Medicine, New York, New York 10016, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HCO.0b013e328352220eDOI Listing
May 2012

Novel mechanisms of trafficking defect caused by KCNQ1 mutations found in long QT syndrome.

J Biol Chem 2009 Dec 13;284(50):35122-33. Epub 2009 Oct 13.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo 113-8510, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.017293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787373PMC
December 2009

Phenotypic overlap of cardiac sodium channelopathies: individual-specific or mutation-specific?

Authors:
Naomasa Makita

Circ J 2009 May 31;73(5):810-7. Epub 2009 Mar 31.

Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1253/circj.cj-09-0014DOI Listing
May 2009

Differential modulation of late sodium current by protein kinase A in R1623Q mutant of LQT3.

Life Sci 2009 Mar 9;84(11-12):380-7. Epub 2009 Jan 9.

Second Department of Internal Medicine, University of Occupational and Environmental Health Japan, Kitakyushu 807-8555, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lfs.2009.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747087PMC
March 2009

Cardiac ion channel gene mutations in sudden infant death syndrome.

Pediatr Res 2008 Nov;64(5):482-7

Department of Pediatrics, Yamagata University School of Medicine, Yamagata 990-9585, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1203/PDR.0b013e3181841ecaDOI Listing
November 2008

Absence of a trafficking defect in R1232W/T1620M, a double SCN5A mutant responsible for Brugada syndrome.

Circ J 2008 Jun;72(6):1018-9

Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, Sapporo 060-8638, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1253/circj.72.1018DOI Listing
June 2008

Genetic polymorphisms and arrhythmia susceptibility.

Circ J 2007 ;71 Suppl A:A54-60

Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Kita-ku, Sapporo 060-8638, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1253/circj.71.a54DOI Listing
June 2011

Novel SCN5A mutation (Q55X) associated with age-dependent expression of Brugada syndrome presenting as neurally mediated syncope.

Heart Rhythm 2007 Apr 10;4(4):516-9. Epub 2006 Nov 10.

Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2006.10.028DOI Listing
April 2007

Congenital atrial standstill associated with coinheritance of a novel SCN5A mutation and connexin 40 polymorphisms.

Heart Rhythm 2005 Oct;2(10):1128-34

Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2005.06.032DOI Listing
October 2005

Tetrodotoxin-resistant Na+ channels in human neuroblastoma cells are encoded by new variants of Nav1.5/SCN5A.

Eur J Neurosci 2005 Aug;22(4):793-801

Department of Physiology, Graduate School of Medical & Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1460-9568.2005.04280.xDOI Listing
August 2005

Double SCN5A mutation underlying asymptomatic Brugada syndrome.

Heart Rhythm 2005 Mar;2(3):285-92

Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2004.11.022DOI Listing
March 2005

Intrinsic mechanism of the enhanced rate-dependent QT shortening in the R1623Q mutant of the LQT3 syndrome.

Cardiovasc Res 2005 Jan;65(1):138-47

Second Department of Internal Medicine, University of Occupational and Environmental Health Japan, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cardiores.2004.09.025DOI Listing
January 2005

Drug-induced long-QT syndrome associated with a subclinical SCN5A mutation.

Circulation 2002 Sep;106(10):1269-74

Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.cir.0000027139.42087.b6DOI Listing
September 2002

A mutant cardiac sodium channel with multiple biophysical defects associated with overlapping clinical features of Brugada syndrome and cardiac conduction disease.

Cardiovasc Res 2002 Feb;53(2):348-54

Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-Ku, Sapporo 060-8638, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0008-6363(01)00494-1DOI Listing
February 2002