Naoki Osada

Naoki Osada

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Naoki Osada

Publications by authors named "Naoki Osada"

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Conversion of human fibroblasts into multipotent cells by cell-penetrating peptides.

Biochem Biophys Res Commun 2019 Oct 10;518(1):134-140. Epub 2019 Aug 10.

Division of Stem Cell Regulation, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Tochigi, 329-0498, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2019.08.021DOI Listing
October 2019

Tuning of ion-release capability from bio-ceramic-polymer composites for enhancing cellular activity.

R Soc Open Sci 2019 Sep 11;6(9):190612. Epub 2019 Sep 11.

Nagoya Institute of Technology, Gokiso cho, Showa ku, Nagoya 466-8555, Japan.

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http://dx.doi.org/10.1098/rsos.190612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774980PMC
September 2019

Eradication of Central Nervous System Leukemia of T-Cell Origin with a Brain-Permeable LSD1 Inhibitor.

Clin Cancer Res 2019 03 5;25(5):1601-1611. Epub 2018 Dec 5.

Division of Stem Cell Regulation, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397674PMC
March 2019

Ancient hybridization and admixture in macaques (genus Macaca) inferred from whole genome sequences.

Mol Phylogenet Evol 2018 10 31;127:376-386. Epub 2018 Mar 31.

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, Sichuan, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.ympev.2018.03.038DOI Listing
October 2018

Comprehensive phylogenomic analysis reveals a novel cluster of simian endogenous retroviral sequences in Colobinae monkeys.

Am J Primatol 2018 07 12;80(7):e22882. Epub 2018 Jun 12.

Department of Information Science and Technology, Hokkaido University, Hokkaido, Japan.

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http://dx.doi.org/10.1002/ajp.22882DOI Listing
July 2018

Myeloma Cells Are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex, Which Senses Lipopolysaccharide.

Cancer Res 2018 04 23;78(7):1766-1778. Epub 2018 Jan 23.

Division of Stem Cell Regulation, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-17-2446DOI Listing
April 2018

Lysine-specific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells.

Oncotarget 2018 Jan 8;9(5):6450-6462. Epub 2018 Jan 8.

Division of Stem Cell Regulation, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.

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http://dx.doi.org/10.18632/oncotarget.24030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814224PMC
January 2018

- and -regulatory Effects on Gene Expression in a Natural Population of .

Genetics 2017 08 14;206(4):2139-2148. Epub 2017 Jun 14.

Department of Biological Sciences, Tokyo Metropolitan University, Hachioji, Japan

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http://www.genetics.org/lookup/doi/10.1534/genetics.117.2014
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http://dx.doi.org/10.1534/genetics.117.201459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560811PMC
August 2017

A Generalized Linear Model for Decomposing -regulatory, Parent-of-Origin, and Maternal Effects on Allele-Specific Gene Expression.

G3 (Bethesda) 2017 07 5;7(7):2227-2234. Epub 2017 Jul 5.

Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Hokkaido 060-0814, Japan

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http://g3journal.org/lookup/doi/10.1534/g3.117.042895
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http://dx.doi.org/10.1534/g3.117.042895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499130PMC
July 2017

Translational Repression of a Splice Variant of Cynomolgus Macaque CXCL1L by Its C-Terminal Sequence.

J Interferon Cytokine Res 2017 03 10;37(3):129-138. Epub 2017 Feb 10.

5 The Health and Kampo Institute , Sendai, Japan .

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http://dx.doi.org/10.1089/jir.2016.0085DOI Listing
March 2017

Genome-scale approaches for studying human and non-human primate evolution.

Authors:
Naoki Osada

Genes Genet Syst 2015 ;90(3):121-2

Department of Population Genetics, National Institute of Genetics.

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http://dx.doi.org/10.1266/ggs.90.121DOI Listing
August 2016

Genetic diversity in humans and non-human primates and its evolutionary consequences.

Authors:
Naoki Osada

Genes Genet Syst 2015 ;90(3):133-45

Department of Population Genetics, National Institute of Genetics.

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http://dx.doi.org/10.1266/ggs.90.133DOI Listing
August 2016

Complex patterns of cis-regulatory polymorphisms in ebony underlie standing pigmentation variation in Drosophila melanogaster.

Mol Ecol 2015 12 20;24(23):5829-41. Epub 2015 Nov 20.

Department of Biological Sciences, Tokyo Metropolitan University, Minamiosawa 1-1, Hachioji, 192-0397, Japan.

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http://dx.doi.org/10.1111/mec.13432DOI Listing
December 2015

Dopamine receptor genes and evolutionary differentiation in the domestication of fighting cocks and long-crowing chickens.

PLoS One 2014 31;9(7):e101778. Epub 2014 Jul 31.

National Institute of Genetics, Shizuoka, Japan; SOKENDAI, Department of Genetics, Graduate School of Advanced Studies, Hayama, Kanagawa, Japan; CBRC, BESE, King Abdullah University of Science and Technology, Thuwal, KSA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101778PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117491PMC
October 2015

CYP2D44 polymorphisms in cynomolgus and rhesus macaques.

Mol Biol Rep 2015 Jul 15;42(7):1149-55. Epub 2015 Feb 15.

Pharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd., 16-1 Minami Akasaka, Kainan, Wakayama, 642-0017, Japan,

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http://link.springer.com/10.1007/s11033-015-3863-0
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http://dx.doi.org/10.1007/s11033-015-3863-0DOI Listing
July 2015

Population genetics of non-genetic traits: evolutionary roles of stochasticity in gene expression.

Gene 2015 May 6;562(1):16-21. Epub 2015 Mar 6.

Department of Fish Ecology and Evolution, EAWAG, Swiss Federal Institute of Aquatic Science and Technology, 6047 Kastanienbaum, Switzerland; Research Faculty of Agriculture, Hokkaido University, N9W9 Kita, Sapporo 060-8589, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2015.03.011DOI Listing
May 2015

Whole-genome sequencing of six Mauritian Cynomolgus macaques (Macaca fascicularis) reveals a genome-wide pattern of polymorphisms under extreme population bottleneck.

Genome Biol Evol 2015 Mar 23;7(3):821-30. Epub 2015 Mar 23.

Laboratoire d'Immunogénétique Moléculaire (LIMT, EA3034), Faculté de Médecine Purpan, Université Paul Sabatier, Toulouse III, France

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https://academic.oup.com/gbe/article-lookup/doi/10.1093/gbe/
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http://dx.doi.org/10.1093/gbe/evv033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322541PMC
March 2015

The genome landscape of the african green monkey kidney-derived vero cell line.

DNA Res 2014 Dec 28;21(6):673-83. Epub 2014 Sep 28.

Department of Biochemistry and Cell Biology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan

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http://dx.doi.org/10.1093/dnares/dsu029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263300PMC
December 2014

Prdm9 polymorphism unveils mouse evolutionary tracks.

DNA Res 2014 Jun 20;21(3):315-26. Epub 2014 Jan 20.

Mammalian Genetics Laboratory, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, Japan

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http://dx.doi.org/10.1093/dnares/dst059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060951PMC
June 2014

Whole-genome sequencing of tibetan macaque (Macaca Thibetana) provides new insight into the macaque evolutionary history.

Mol Biol Evol 2014 Jun 18;31(6):1475-89. Epub 2014 Mar 18.

Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu, People's Republic of China

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http://dx.doi.org/10.1093/molbev/msu104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032132PMC
June 2014

Finding the factors of reduced genetic diversity on X chromosomes of Macaca fascicularis: male-driven evolution, demography, and natural selection.

Genetics 2013 Nov 11;195(3):1027-35. Epub 2013 Sep 11.

Department of Population Genetics, National Institute of Genetics, Mishima, Shizuoka 4118540, Japan.

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http://dx.doi.org/10.1534/genetics.113.156703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813834PMC
November 2013

Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history.

Genes Cells 2013 Jan 12;18(1):1-16. Epub 2012 Nov 12.

Department of Molecular Enzymology, Kumamoto University Graduate School of Medical Sciences, Honjo, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1111/gtc.12013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568907PMC
January 2013

Weak selection and protein evolution.

Genetics 2012 Sep;192(1):15-31

Division of Evolutionary Genetics, Department of Population Genetics, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan.

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http://dx.doi.org/10.1534/genetics.112.140178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430532PMC
September 2012

Evolutionary rates of commonly used nuclear and organelle markers of Arabidopsis relatives (Brassicaceae).

Gene 2012 May 9;499(1):194-201. Epub 2012 Mar 9.

Department of Life Sciences, National Cheng-Kung University, Tainan 701, Taiwan.

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http://dx.doi.org/10.1016/j.gene.2012.02.037DOI Listing
May 2012

Mitochondrial-nuclear interactions and accelerated compensatory evolution: evidence from the primate cytochrome C oxidase complex.

Mol Biol Evol 2012 Jan 1;29(1):337-46. Epub 2011 Sep 1.

Division of Evolutionary Genetics, Department of Population Genetics, National Institute of Genetics, Mishima, Japan.

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http://dx.doi.org/10.1093/molbev/msr211DOI Listing
January 2012

Phylogenetic inconsistency caused by ancient sex-biased gene migration.

Authors:
Naoki Osada

PLoS One 2011 29;6(9):e25549. Epub 2011 Sep 29.

Department of Population Genetics, National Institute of Genetics, Mishima, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025549PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183042PMC
January 2012

Characterization of MHC class I transcripts of a Malaysian cynomolgus macaque by high-throughput pyrosequencing and EST libraries.

Immunogenetics 2011 Nov 28;63(11):703-13. Epub 2011 Jun 28.

Laboratoire d'Immunogénétique moléculaire, EA 3034, Faculté de Médecine Purpan, Université Paul Sabatier, Toulouse 3, France.

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http://dx.doi.org/10.1007/s00251-011-0550-8DOI Listing
November 2011

Population genetics in nonmodel organisms: II. natural selection in marginal habitats revealed by deep sequencing on dual platforms.

Mol Biol Evol 2011 Oct 18;28(10):2833-42. Epub 2011 Apr 18.

State Key Laboratory of Biocontrol and Key Laboratory of Gene Engineering of the Ministry of Education, Sun Yat-sen University, Guangzhou, China.

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http://dx.doi.org/10.1093/molbev/msr102DOI Listing
October 2011

Novel DNA sequence isolated from blood donors with high transaminase levels.

Hepatol Res 2011 Oct 1;41(10):971-81. Epub 2011 Jul 1.

Central Blood Institute, Japanese Red Cross, Tokyo Department of Population Genetics, National Institute of Genetics, Mishima Saitama Blood Center, Japanese Red Cross, Saitama, Japan.

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http://dx.doi.org/10.1111/j.1872-034X.2011.00848.xDOI Listing
October 2011

CpG site degeneration triggered by the loss of functional constraint created a highly polymorphic macaque drug-metabolizing gene, CYP1A2.

BMC Evol Biol 2011 Oct 1;11:283. Epub 2011 Oct 1.

Pharmacokinetics and Bioanalysis Center, Shin Nippon BiomedicalLaboratories, Ltd., Kainan, Wakayama 642-0017, Japan.

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http://dx.doi.org/10.1186/1471-2148-11-283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199271PMC
October 2011

A family tree of vertebrate chemokine receptors for a unified nomenclature.

Dev Comp Immunol 2011 Jul 2;35(7):705-15. Epub 2011 Feb 2.

Department of Molecular Enzymology, Kumamoto University Faculty of Life Sciences, Honjo, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1016/j.dci.2011.01.019DOI Listing
July 2011

The evolution of mammalian chemokine genes.

Cytokine Growth Factor Rev 2010 Aug;21(4):253-62

Department of Molecular Enzymology, Faculty of Life Sciences, Kumamoto University, Honjo, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1016/j.cytogfr.2010.03.004DOI Listing
August 2010

Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta.

Mol Ecol 2010 Jul 23;19(14):2884-95. Epub 2010 Jun 23.

Department of Biomedical Resources, National Institute of Biomedical Innovation, 7-6-8 Saito-Asagi, Ibraki, Osaka 567-0085, Japan.

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http://dx.doi.org/10.1111/j.1365-294X.2010.04687.xDOI Listing
July 2010

Genetic variants of CYP3A4 and CYP3A5 in cynomolgus and rhesus macaques.

Drug Metab Dispos 2010 Feb 12;38(2):209-14. Epub 2009 Nov 12.

Genome Research Group, Pharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd., 16-1 Minami Akasaka, Kainan, Wakayama 642-0017, Japan.

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http://dx.doi.org/10.1124/dmd.109.029710DOI Listing
February 2010

IL-10 is a negative regulatory factor of CAWS-vasculitis in CBA/J mice as assessed by comparison with Bruton's tyrosine kinase-deficient CBA/N mice.

J Immunol 2009 Sep 12;183(5):3417-24. Epub 2009 Aug 12.

Laboratory for Immunopharmacology of Microbial Products, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.

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http://dx.doi.org/10.4049/jimmunol.0802484DOI Listing
September 2009

Collection of Macaca fascicularis cDNAs derived from bone marrow, kidney, liver, pancreas, spleen, and thymus.

BMC Res Notes 2009 Sep 29;2:199. Epub 2009 Sep 29.

Department of Biomedical Resources, National Institute of Biomedical Innovation, 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.

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http://dx.doi.org/10.1186/1756-0500-2-199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762985PMC
September 2009

Development of an integrative database with 499 novel microsatellite markers for Macaca fascicularis.

BMC Genet 2009 Jun 5;10:24. Epub 2009 Jun 5.

Tsukuba Primate Research Center, National Institute of Biomedical Innovation, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1186/1471-2156-10-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702342PMC
June 2009

Quantifying dominance and deleterious effect on human disease genes.

Proc Natl Acad Sci U S A 2009 Jan 12;106(3):841-6. Epub 2009 Jan 12.

National Institute of Biomedical Innovation, 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.

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http://dx.doi.org/10.1073/pnas.0810433106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630084PMC
January 2009

Duplication and gene conversion in the Drosophila melanogaster genome.

PLoS Genet 2008 Dec 12;4(12):e1000305. Epub 2008 Dec 12.

National Institute of Biomedical Innovation, Osaka, Japan.

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http://dx.doi.org/10.1371/journal.pgen.1000305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588116PMC
December 2008

Expressed sequence tags from cynomolgus monkey (Macaca fascicularis) liver: a systematic identification of drug-metabolizing enzymes.

FEBS Lett 2008 Jan 31;582(2):351-8. Epub 2007 Dec 31.

Division of Genetic Diagnosis, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan.

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http://doi.wiley.com/10.1016/j.febslet.2007.12.031
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http://dx.doi.org/10.1016/j.febslet.2007.12.031DOI Listing
January 2008

Inference of expression-dependent negative selection based on polymorphism and divergence in the human genome.

Authors:
Naoki Osada

Mol Biol Evol 2007 Aug 2;24(8):1622-6. Epub 2007 May 2.

Department of Biomedical Resources, National Institute of Biomedical Innovation, Osaka, Japan.

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http://dx.doi.org/10.1093/molbev/msm080DOI Listing
August 2007

Aberrant termination of reproduction-related TMEM30C transcripts in the hominoids.

Gene 2007 May 12;392(1-2):151-6. Epub 2006 Dec 12.

Division of Biomedical Research Resources, National Institute of Biomedical Innovation, 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.

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http://dx.doi.org/10.1016/j.gene.2006.11.021DOI Listing
May 2007

Identification of a novel CXCL1-like chemokine gene in macaques and its inactivation in hominids.

J Interferon Cytokine Res 2007 Jan;27(1):32-7

Department of Molecular Enzymology, Kumamoto University Graduate School of Medical Sciences, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1089/jir.2007.0099DOI Listing
January 2007

Genomic inferences of the cis-regulatory nucleotide polymorphisms underlying gene expression differences between Drosophila melanogaster mating races.

Mol Biol Evol 2006 Aug 5;23(8):1585-91. Epub 2006 Jun 5.

Division of Biomedical Research Resources, National Institute of Biomedical Innovation, Ibaraki, Osaka, Japan.

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http://academic.oup.com/mbe/article/23/8/1585/967525/Genomic
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http://dx.doi.org/10.1093/molbev/msl023DOI Listing
August 2006

Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs.

Mol Biol Evol 2005 Oct 8;22(10):1976-82. Epub 2005 Jun 8.

Division of Genetic Resources, National Institute of Infectious Diseases, Tokyo, Japan.

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http://dx.doi.org/10.1093/molbev/msi187DOI Listing
October 2005

Evolution of sexual isolation during secondary contact: genotypic versus phenotypic changes in laboratory populations.

Am Nat 2005 Apr 28;165(4):420-8. Epub 2005 Feb 28.

Committee on Evolutionary Biology, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1086/428388DOI Listing
April 2005

Inferring the mode of speciation from genomic data: a study of the great apes.

Genetics 2005 Jan;169(1):259-64

Department of Ecology and Evolution, University of Chicago, Chicago, Illinois 60637, USA.

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http://www.genetics.org/cgi/doi/10.1534/genetics.104.029231
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http://dx.doi.org/10.1534/genetics.104.029231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448895PMC
January 2005

Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis.

BMC Genomics 2003 Aug 9;4(1):32. Epub 2003 Aug 9.

Centre for Cancer Therapeutics, Ottawa Regional Cancer Centre, 503 Smyth Rd, Ottawa, ON, K1H 1C4, Canada.

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http://dx.doi.org/10.1186/1471-2164-4-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC194569PMC
August 2003

Analysis of 5'-end sequences of chimpanzee cDNAs.

Genome Res 2003 May;13(5):1022-6

Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8562, Japan.

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http://dx.doi.org/10.1101/gr.783103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC430928PMC
May 2003

Cynomolgus monkey testicular cDNAs for discovery of novel human genes in the human genome sequence.

BMC Genomics 2002 Dec 23;3(1):36. Epub 2002 Dec 23.

Division of Genetic Resources, National Institute of Infectious Diseases, 1-23-1 Toyama-cho, Shinjuku-ku, 162-8640, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140308PMC
http://dx.doi.org/10.1186/1471-2164-3-36DOI Listing
December 2002

Prediction of unidentified human genes on the basis of sequence similarity to novel cDNAs from cynomolgus monkey brain.

Genome Biol 2002 19;3(1):RESEARCH0006. Epub 2001 Dec 19.

Division of Genetic Resources, National Institute of Infectious Diseases, 1-23-1 Toyama-cho, Shinjuku-ku, 162-8640, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150453PMC
http://dx.doi.org/10.1186/gb-2001-3-1-research0006DOI Listing
May 2002