Nanshan Zhong

Nanshan Zhong

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Age and Sex Distribution of Chinese Chronic Cough Patients and Their Relationship With Capsaicin Cough Sensitivity.

Allergy Asthma Immunol Res 2019 Nov;11(6):871-884

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.4168/aair.2019.11.6.871DOI Listing
November 2019

Clinical utility of ultrahigh fractional exhaled nitric oxide in predicting bronchial hyperresponsiveness in patients with suspected asthma.

Postgrad Med J 2019 Oct 11;95(1128):541-546. Epub 2019 Jul 11.

Department of Respirology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China

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http://dx.doi.org/10.1136/postgradmedj-2018-136333DOI Listing
October 2019

Role of Plasma Calreticulin in the Prediction of Severity in Septic Patients.

Dis Markers 2019 12;2019:8792640. Epub 2019 Sep 12.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.

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http://dx.doi.org/10.1155/2019/8792640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757249PMC
September 2019

Uncontrolled asthma phenotypes defined from parameters using quantitative CT analysis.

Eur Radiol 2019 Jun 7;29(6):2848-2858. Epub 2019 Jan 7.

National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.

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http://dx.doi.org/10.1007/s00330-018-5913-1DOI Listing
June 2019

Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough.

Respir Res 2019 Jun 6;20(1):112. Epub 2019 Jun 6.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Rd, Guangzhou, 510120, People's Republic of China.

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http://dx.doi.org/10.1186/s12931-019-1077-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554907PMC
June 2019

The tree shrew is a promising model for the study of influenza B virus infection.

Virol J 2019 06 7;16(1):77. Epub 2019 Jun 7.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, People's Republic of China.

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http://dx.doi.org/10.1186/s12985-019-1171-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555921PMC
June 2019

Identification and Modulation of Microenvironment Is Crucial for Effective Mesenchymal Stromal Cell Therapy in Acute Lung Injury.

Am J Respir Crit Care Med 2019 May;199(10):1214-1224

1 The State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

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https://www.atsjournals.org/doi/10.1164/rccm.201802-0356OC
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http://dx.doi.org/10.1164/rccm.201802-0356OCDOI Listing
May 2019

Clinical Features and Prognosis of Pulmonary Lymphoepithelioma-like Carcinoma: Summary of Eighty-five Cases.

Clin Lung Cancer 2019 May 24;20(3):e329-e337. Epub 2018 Dec 24.

State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of the Respiratory Health, Shunde Affiliated Hospital of Guangzhou Medical University, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2018.12.014DOI Listing
May 2019

PAK4 Phosphorylates Fumarase and Blocks TGFβ-Induced Cell Growth Arrest in Lung Cancer Cells.

Cancer Res 2019 Apr 25;79(7):1383-1397. Epub 2019 Jan 25.

State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-2575DOI Listing
April 2019

Optimal Starting Age for Lung Cancer Screening With Low-Dose Computed Tomography: A Population Level Analysis.

J Thorac Oncol 2019 Apr;14(4):e82-e84

China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.12.008DOI Listing
April 2019

Computed Tomography-Based Radiomics Signature: A Potential Indicator of Epidermal Growth Factor Receptor Mutation in Pulmonary Adenocarcinoma Appearing as a Subsolid Nodule.

Oncologist 2019 Apr 1. Epub 2019 Apr 1.

Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China

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http://dx.doi.org/10.1634/theoncologist.2018-0706DOI Listing
April 2019

Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology.

Authors:
Jean Bousquet Peter W Hellings Ioana Agache Flore Amat Isabella Annesi-Maesano Ignacio J Ansotegui Josep M Anto Claus Bachert Eric D Bateman Anna Bedbrook Kazi Bennoor Mickael Bewick Carsten Bindslev-Jensen Sinthia Bosnic-Anticevich Isabelle Bosse Jan Brozek Luisa Brussino Giorgio W Canonica Victoria Cardona Thomas Casale Alfonso M Cepeda Sarabia Niels H Chavannes Lorenzo Cecchi Jaime Correia de Sousa Elisio Costa Alvaro A Cruz Wienczyslawa Czarlewski Giuseppe De Carlo Giulia De Feo Pascal Demoly Philippe Devillier Mark S Dykewicz Yehia El-Gamal Esben E Eller Joao A Fonseca Jean-François Fontaine Wytske J Fokkens Maria-Antonieta Guzmán Tari Haahtela Maddalena Illario Juan-Carlos Ivancevich Jocelyne Just Igor Kaidashev Musa Khaitov Omer Kalayci Thomas Keil Ludger Klimek Marek L Kowalski Piotr Kuna Violeta Kvedariene Desiree Larenas-Linnemann Daniel Laune Lan T T Le Karin Lodrup Carlsen Olga Lourenço Bassam Mahboub Alpana Mair Enrica Menditto Branislava Milenkovic Mario Morais-Almeida Ralph Mösges Joaquim Mullol Ruth Murray Robert Naclerio Leyla Namazova-Baranova Ettore Novellino Robyn E O'Hehir Ken Ohta Yoshitaka Okamoto Kimi Okubo Gabrielle L Onorato Susanna Palkonen Petr Panzner Nikos G Papadopoulos Hae-Sim Park Ema Paulino Ruby Pawankar Oliver Pfaar Davor Plavec Ted A Popov Paul Potter Emmanuel P Prokopakis Menachem Rottem Dermot Ryan Johanna Salimäki Boleslaw Samolinski Mario Sanchez-Borges Holger J Schunemann Aziz Sheikh Juan-Carlos Sisul Rojin Rajabian-Söderlund Talant Sooronbaev Cristiana Stellato Teresa To Ana-Maria Todo-Bom Peter-Valentin Tomazic Sanna Toppila-Salmi Antonio Valero Arunas Valiulis Erkka Valovirta Maria-Teresa Ventura Martin Wagenmann De Yun Wang Dana Wallace Susan Waserman Magnus Wickman Arzu Yorgancioglu Luo Zhang Nanshan Zhong Mihaela Zidarn Torsten Zuberbier

J Allergy Clin Immunol 2019 Mar 29;143(3):864-879. Epub 2018 Sep 29.

Comprehensive Allergy Center Charité, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, and Global Allergy and Asthma European Network (GA2LEN), Berlin, Germany.

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http://dx.doi.org/10.1016/j.jaci.2018.08.049DOI Listing
March 2019

Effects of YuPingFeng granules on acute exacerbations of COPD: a randomized, placebo-controlled study.

Int J Chron Obstruct Pulmon Dis 2018;13:3107-3114. Epub 2018 Oct 4.

Department of Biostatistics, Southern Medical University, Guangzhou, People's Republic of China.

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https://www.dovepress.com/effects-of-yupingfeng-granules-on-
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http://dx.doi.org/10.2147/COPD.S170555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174891PMC
March 2019

Traffic-related air pollution induces non-allergic eosinophilic airway inflammation and cough hypersensitivity in guinea-pigs.

Clin Exp Allergy 2019 Mar 14;49(3):366-377. Epub 2019 Jan 14.

State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

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http://doi.wiley.com/10.1111/cea.13308
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http://dx.doi.org/10.1111/cea.13308DOI Listing
March 2019

Impacts of event-specific air quality improvements on total hospital admissions and reduced systemic inflammation in COPD patients.

PLoS One 2019 20;14(3):e0208687. Epub 2019 Mar 20.

State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208687PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426198PMC
March 2019

Tiotropium discontinuation in patients with early-stage COPD: a prospective observational cohort study.

ERJ Open Res 2019 Feb 18;5(1). Epub 2019 Feb 18.

The State Key Laboratory of Respiratory Disease, National Clinical Researcher Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.1183/23120541.00175-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378343PMC
February 2019

Differential effects of size-specific particulate matter on emergency department visits for respiratory and cardiovascular diseases in Guangzhou, China.

Environ Pollut 2018 Dec 27;243(Pt A):336-345. Epub 2018 Aug 27.

Guangzhou Institute of Respiratory Health, Guangdong Province, China. Electronic address:

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http://dx.doi.org/10.1016/j.envpol.2018.08.068DOI Listing
December 2018

A specific subtype of chronic obstructive pulmonary disease classified by forced vital capacity.

J Thorac Dis 2018 Dec;10(12):6547-6556

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute for Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.

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http://dx.doi.org/10.21037/jtd.2018.12.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344753PMC
December 2018

Clinical Practice Guidelines for Diagnosis and Management of Cough-Chinese Thoracic Society (CTS) Asthma Consortium.

J Thorac Dis 2018 Nov;10(11):6314-6351

State Key Laboratory of Respiratory Diseases, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China.

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http://jtd.amegroups.com/article/view/25427/19122
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http://dx.doi.org/10.21037/jtd.2018.09.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297434PMC
November 2018

Clinical application of invasive cardiopulmonary exercise test for dyspnea diagnosis in Chinese people.

J Thorac Dis 2018 Nov;10(Suppl 33):S4176-S4178

Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510180, China.

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http://dx.doi.org/10.21037/jtd.2018.10.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297497PMC
November 2018

Tree shrew as a new animal model to study the pathogenesis of avian influenza (H9N2) virus infection.

Emerg Microbes Infect 2018 Oct 10;7(1):166. Epub 2018 Oct 10.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.

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http://dx.doi.org/10.1038/s41426-018-0167-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177411PMC
October 2018

High-flow nasal cannula in adults with acute respiratory failure and after extubation: a systematic review and meta-analysis.

Respir Res 2018 Oct 16;19(1):202. Epub 2018 Oct 16.

State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute for Respiratory Health, Guangzhou, China.

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https://respiratory-research.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s12931-018-0908-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192218PMC
October 2018

Bronchiectasis after bronchial thermoplasty.

J Thorac Dis 2018 Oct;10(10):E721-E726

Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.

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http://dx.doi.org/10.21037/jtd.2018.09.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236163PMC
October 2018

Clinical Correlations of Transcriptional Profile in Patients Infected With Avian Influenza H7N9 Virus.

J Infect Dis 2018 09;218(8):1238-1248

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University.

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http://dx.doi.org/10.1093/infdis/jiy317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129114PMC
September 2018

Dual effects of human neutrophil peptides in a mouse model of pneumonia and ventilator-induced lung injury.

Respir Res 2018 Sep 29;19(1):190. Epub 2018 Sep 29.

The State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510000, Guangdong, China.

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http://dx.doi.org/10.1186/s12931-018-0869-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162902PMC
September 2018

The effects of CXCL10 polymorphisms on COPD susceptibility.

Mol Genet Genomics 2018 Jun 28;293(3):649-655. Epub 2017 Dec 28.

State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510120, Guangdong, China.

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http://dx.doi.org/10.1007/s00438-017-1408-zDOI Listing
June 2018

Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice.

J Thorac Dis 2018 Jun;10(6):3232-3243

State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou 510000, China.

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http://dx.doi.org/10.21037/jtd.2018.05.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051853PMC
June 2018

Cappariloside A shows antiviral and better anti-inflammatory effects against influenza virus via regulating host IFN signaling, in vitro and vivo.

Life Sci 2018 May 17;200:115-125. Epub 2018 Mar 17.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, (Guangzhou Medical University), Guangzhou 510120, China; Macau University of Science and Technology, Macau 519020, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00243205183013
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http://dx.doi.org/10.1016/j.lfs.2018.03.033DOI Listing
May 2018

As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.

N Engl J Med 2018 May;378(20):1877-1887

From the Division of Pulmonology, Department of Medicine, University of Cape Town, Cape Town, South Africa (E.D.B.); Woolcock Institute of Medical Research, University of Sydney, Sydney (H.K.R.); Firestone Institute for Respiratory Health, St. Joseph's Healthcare and Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON (P.M.O.), and the Institute for Heart and Lung Health, University of British Columbia, Vancouver (J.M.F.) - both in Canada; Airway Disease Section, National Heart and Lung Institute, Imperial College, London (P.J.B.); State Key Laboratory of Respiratory Diseases, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (N.Z.); AstraZeneca Research and Development, Gothenburg, Sweden (C.K., C.J.); AstraZeneca Research and Development, Barcelona (R.L.); and AstraZeneca Research and Development, Warsaw, Poland (A.S.-P.).

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http://dx.doi.org/10.1056/NEJMoa1715275DOI Listing
May 2018

Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.

N Engl J Med 2018 05;378(20):1865-1876

From the Firestone Institute for Respiratory Health, St. Joseph's Healthcare and Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON (P.M.O.), and the Institute for Heart and Lung Health, University of British Columbia, Vancouver (J.M.F.) - both in Canada; the Division of Pulmonology, Department of Medicine, University of Cape Town, Cape Town, South Africa (E.D.B.); Airway Disease Section, National Heart and Lung Institute, Imperial College, London (P.J.B.); State Key Laboratory of Respiratory Diseases, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (N.Z.); AstraZeneca Research and Development, Gothenburg, Sweden (C.K., C.J., S.I.); AstraZeneca Research and Development, Barcelona (R.L.); and Woolcock Institute of Medical Research, University of Sydney, Sydney (H.K.R.).

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http://dx.doi.org/10.1056/NEJMoa1715274DOI Listing
May 2018

Multi-level analysis of bacteria isolated from inpatients in respiratory departments in China.

J Thorac Dis 2018 May;10(5):2666-2675

State Key Laboratory of Respiratory Diseases, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510230, China.

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http://dx.doi.org/10.21037/jtd.2018.04.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006077PMC
May 2018

Prone position ventilation support for acute exacerbation of interstitial lung disease?

Clin Respir J 2018 Apr 2;12(4):1372-1380. Epub 2017 Aug 2.

Department of Critical Care Medicine, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.

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http://dx.doi.org/10.1111/crj.12665DOI Listing
April 2018

Immunization with an adenovirus-vectored TB vaccine containing Ag85A-Mtb32 effectively alleviates allergic asthma.

J Mol Med (Berl) 2018 04 4;96(3-4):249-263. Epub 2018 Jan 4.

Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 190 Kai Yuan Avenue, Science Park, Guangzhou, China.

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http://dx.doi.org/10.1007/s00109-017-1614-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859035PMC
April 2018

Malignant solitary pulmonary nodules: assessment of mass growth rate and doubling time at follow-up CT.

J Thorac Dis 2018 Apr;10(Suppl 7):S797-S806

The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China.

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http://jtd.amegroups.com/article/view/20507/15787
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http://dx.doi.org/10.21037/jtd.2018.04.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945695PMC
April 2018

Infrared thermal imaging and Doppler vessel pressurization ultrasonography to detect lower extremity deep vein thrombosis: Diagnostic accuracy study.

Clin Respir J 2018 Mar 10;12(3):1118-1124. Epub 2017 May 10.

Guangzhou AIB Polytech College, Guangzhou, China.

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http://dx.doi.org/10.1111/crj.12639DOI Listing
March 2018

Asthma Phenotypes Defined From Parameters Obtained During Recovery From a Hospital-Treated Exacerbation.

J Allergy Clin Immunol Pract 2018 Nov - Dec;6(6):1960-1967. Epub 2018 Mar 1.

Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132198183010
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http://dx.doi.org/10.1016/j.jaip.2018.02.012DOI Listing
March 2018

Effects of leukotriene D and histamine nasal challenge on airway responsiveness and inflammation in persistent allergic rhinitis patients.

Clin Respir J 2018 Feb 1;12(2):587-594. Epub 2016 Nov 1.

State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.

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http://doi.wiley.com/10.1111/crj.12566
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http://dx.doi.org/10.1111/crj.12566DOI Listing
February 2018

Tanshinone IIA sulfonate protects against cigarette smoke-induced COPD and down-regulation of CFTR in mice.

Sci Rep 2018 01 10;8(1):376. Epub 2018 Jan 10.

State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

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http://dx.doi.org/10.1038/s41598-017-18745-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762644PMC
January 2018

Stage I synchronous multiple primary non-small cell lung cancer: CT findings and the effect of TNM staging with the 7th and 8th editions on prognosis.

J Thorac Dis 2017 Dec;9(12):5335-5344

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.

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http://dx.doi.org/10.21037/jtd.2017.12.101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757034PMC
December 2017

Chinese consensus statement on standard procedure and perioperative management of bronchial thermoplasty.

J Thorac Dis 2017 Dec;9(12):5507-5514

Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.

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http://dx.doi.org/10.21037/jtd.2017.12.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756944PMC
December 2017

Pleural fluid carcinoembryonic antigen as a biomarker for the discrimination of tumor-related pleural effusion.

Clin Respir J 2017 Nov 25;11(6):881-886. Epub 2016 Jan 25.

Department of Cardiothoracic Surgery, Guangzhou Institute of Respiratory Disease, State Key Laboratary of Respiratory Disease, The First Hospital Affiliated to Guangzhou Medical University, Guangzhou, 510120, Guangdong Province, China.

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http://doi.wiley.com/10.1111/crj.12431
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http://dx.doi.org/10.1111/crj.12431DOI Listing
November 2017

RACK1 forms a complex with FGFR1 and PKM2, and stimulates the growth and migration of squamous lung cancer cells.

Mol Carcinog 2017 Nov 15;56(11):2391-2399. Epub 2017 Sep 15.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, Department of Respiratory Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, P. R. China.

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http://dx.doi.org/10.1002/mc.22663DOI Listing
November 2017

Long-term effects of adenotonsillectomy on serum-specific immunoglobulin E.

Pediatr Res 2017 Nov 2;82(5):801-805. Epub 2017 Aug 2.

State Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Laboratory of ENT-HNS Disease, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.1038/pr.2017.165DOI Listing
November 2017

Reference values for spirometry in Chinese aged 4-80 years.

J Thorac Dis 2017 Nov;9(11):4538-4549

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Diseases, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.

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http://jtd.amegroups.com/article/view/17180/13821
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http://dx.doi.org/10.21037/jtd.2017.10.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720964PMC
November 2017

Reduced nuclear translocation of serum response factor is associated with skeletal muscle atrophy in a cigarette smoke-induced mouse model of COPD.

Int J Chron Obstruct Pulmon Dis 2017 20;12:581-587. Epub 2017 Feb 20.

Guangzhou Institute of Respiratory Disease, State Key Laboratory of Respiratory Diseases, The 1st Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.

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http://dx.doi.org/10.2147/COPD.S109243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327903PMC
October 2017

Sputum microbiota in severe asthma patients: Relationship to eosinophilic inflammation.

Respir Med 2017 10 25;131:192-198. Epub 2017 Aug 25.

State Key Laboratory of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2017.08.016DOI Listing
October 2017

Association between IRGM polymorphisms and tuberculosis risk: A meta-analysis.

Medicine (Baltimore) 2017 Oct;96(43):e8189

aState Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University bAcademy of Orthopedics of Guangdong Province, Department of Respiratory Disease, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.1097/MD.0000000000008189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671819PMC
October 2017

Thermoneutral housing temperature regulates T-regulatory cell function and inhibits ovabumin-induced asthma development in mice.

Sci Rep 2017 08 2;7(1):7123. Epub 2017 Aug 2.

State Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Guangzhou, 510120, China.

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http://dx.doi.org/10.1038/s41598-017-07471-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540912PMC
August 2017

Human infections with recently-emerging highly pathogenic H7N9 avian influenza virus in China.

J Infect 2017 07 6;75(1):71-75. Epub 2017 Apr 6.

CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing, China; Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, China. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2017.04.001DOI Listing
July 2017

A female patient with recurrent lung lesion and hilar lymphadenopathy.

J Thorac Dis 2017 Jul;9(7):1858-1863

Department of Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Disease, State Key Laboratory of Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China.

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http://dx.doi.org/10.21037/jtd.2017.06.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542938PMC
July 2017

Allergen sensitization affected the change trend of prevalence of symptoms of rhinitis coexisting with wheeze among adolescents in Guangzhou City from 1994 to 2009.

Pediatr Allergy Immunol 2017 06;28(4):340-347

Department of Allergy & Clinical Immunology, State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.1111/pai.12709DOI Listing
June 2017

Laryngeal Reflux and Symptoms Need Further Elucidation Using New Techniques.

Am J Gastroenterol 2017 05;112(5):811-812

State Key Laboratory of Respiratory Disease, Department of Otolaryngology - Head and Neck Surgery, Laboratory of ENT-HNS Disease, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.1038/ajg.2017.25DOI Listing
May 2017

Asthma control using fluticasone propionate/salmeterol in Asian and non-Asian populations: a post hoc analysis of the GOAL study.

BMC Pulm Med 2017 Apr 28;17(1):75. Epub 2017 Apr 28.

State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.1186/s12890-017-0410-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410062PMC
April 2017

Aurantiamide acetate from baphicacanthus cusia root exhibits anti-inflammatory and anti-viral effects via inhibition of the NF-κB signaling pathway in Influenza A virus-infected cells.

J Ethnopharmacol 2017 Mar 21;199:60-67. Epub 2017 Jan 21.

State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau 999078, China; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, National Clinical Centre of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical University, 151 Yanjiang Xi Road, Guangzhou 510120, China. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2017.01.038DOI Listing
March 2017

A canine model of tracheal stenosis induced by cuffed endotracheal intubation.

Sci Rep 2017 03 28;7:45357. Epub 2017 Mar 28.

Sate Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.1038/srep45357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368979PMC
March 2017

Eotaxin and IL-4 levels are increased in induced sputum and correlate with sputum eosinophils in patients with nonasthmatic eosinophilic bronchitis.

Medicine (Baltimore) 2017 Mar;96(13):e6492

aState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong bDepartment of Respiratory and Critical Care Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, China.

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http://dx.doi.org/10.1097/MD.0000000000006492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380279PMC
March 2017

Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma.

EBioMedicine 2017 Feb 21;15:137-149. Epub 2016 Dec 21.

Inflammation & Allergic Diseases Research Unit, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China; First Department of Respiratory Disease, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233819PMC
February 2017

Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation.

Sci Rep 2017 02 16;7:42675. Epub 2017 Feb 16.

Inflammation &Allergic Diseases Research Unit, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China.

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http://dx.doi.org/10.1038/srep42675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312001PMC
February 2017

Worldwide malaria incidence and cancer mortality are inversely associated.

Infect Agent Cancer 2017 14;12:14. Epub 2017 Feb 14.

State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 190 Kaiyuan Avenue, Guangzhou Science Park, 510530 Guangzhou, China.

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http://dx.doi.org/10.1186/s13027-017-0117-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307699PMC
February 2017

Two New Alkaloids from the Roots of Baphicacanthus cusia.

Chem Pharm Bull (Tokyo) 2016 ;64(10):1505-1508

State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology.

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http://dx.doi.org/10.1248/cpb.c16-00315DOI Listing
January 2017

Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse model.

Antiviral Res 2017 01 24;137:125-130. Epub 2016 Nov 24.

Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2016.11.016DOI Listing
January 2017

A potential role of transposon IS431 in the loss of mecA gene.

Sci Rep 2017 01 25;7:41237. Epub 2017 Jan 25.

State Key Laboratory of Respiratory Diseases, the first affiliated hospital of Guangzhou Medical College, Guangzhou, China.

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http://dx.doi.org/10.1038/srep41237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264636PMC
January 2017

Uncontrolled asthma and its risk factors in adult Chinese asthma patients.

Ther Adv Respir Dis 2016 12 5;10(6):507-517. Epub 2016 Sep 5.

Department of Respiratory Disease, Xinqiao Hospital, The Third Military Medical University, Chongqing, China.

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http://dx.doi.org/10.1177/1753465816663978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933594PMC
December 2016

A 43-year-old man with cough, expectoration and recurrent wheezing.

J Thorac Dis 2016 Dec;8(12):3468-3477

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.

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http://dx.doi.org/10.21037/jtd.2016.12.106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227256PMC
December 2016

Real-life effectiveness of budesonide/formoterol therapy in asthma: A subanalysis of the SMARTASIA study.

Allergy Asthma Proc 2016 Jan-Feb;37(1):27-34

Department of Respiratory Diseases, China-Japan Friendship Hospital, Peking University, Beijing, China.

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http://dx.doi.org/10.2500/aap.2016.37.3910DOI Listing
November 2016

TIOtropium Safety and Performance In Respimat (TIOSPIR ): Analysis of Asian cohort of COPD patients.

Respirology 2016 11 4;21(8):1397-1403. Epub 2016 Aug 4.

Pulmonary/Critical Care Divison, University of Texas Health Science Center and South Texas Veterans Health Care system, San Antonio, Texas, USA.

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http://dx.doi.org/10.1111/resp.12856DOI Listing
November 2016

FeNO for detecting lower airway involvement in patients with allergic rhinitis.

Exp Ther Med 2016 Oct 23;12(4):2336-2340. Epub 2016 Aug 23.

State Key Laboratory of Respiratory Disease, China Clinical Research Center of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, P.R. China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038870PMC
http://dx.doi.org/10.3892/etm.2016.3616DOI Listing
October 2016

Cigarette smoke extract (CSE) induces transient receptor potential ankyrin 1(TRPA1) expression via activation of HIF1αin A549 cells.

Free Radic Biol Med 2016 10 29;99:498-507. Epub 2016 Jul 29.

State Key Laboratory of Respiratory Diseases, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, No 151 YanJiang Road, Yuexiu Dist., Guangzhou 510120, People's Republic of China.

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.07.028DOI Listing
October 2016

Uncontrolled asthma and its risk factors in Chinese children: A cross-sectional observational study.

J Asthma 2016 09 17;53(7):699-706. Epub 2016 May 17.

a Department of Respiratory Disease , Beijing Children's Hospital, Capital Medical University , Beijing , China.

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http://dx.doi.org/10.3109/02770903.2016.1144199DOI Listing
September 2016

The Functional IgE-Blocking Factor Induced by Allergen-Specific Immunotherapy Correlates with IgG4 Antibodies and a Decrease of Symptoms in House Dust Mite-Allergic Children.

Int Arch Allergy Immunol 2016 7;169(2):113-20. Epub 2016 Apr 7.

Respiratory Department, The Affiliated Nanjing Children's Hospital of Nanjing Medical University, PR China.

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http://dx.doi.org/10.1159/000444391DOI Listing
September 2016

CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea.

N Engl J Med 2016 09 28;375(10):919-31. Epub 2016 Aug 28.

From the Adelaide Institute for Sleep Health (R.D.M., N.A.A.) and the School of Medicine, Faculty of Medicine, Nursing, and Health Sciences (R.D.M., N.A.A., E.H., B.N., C.S.A.), Flinders University, and Sleep Health Service, Respiratory and Sleep Services, Southern Adelaide Local Health Network (R.D.M., N.A.A., S.M.), Adelaide, SA, George Institute for Global Health (E.H., L.B., Q.L., H.A., B.N., C.S.A.), Sydney Medical School (E.H., L.B., Q.L., H.A., B.N., C.S.A.), and Woolcock Institute of Medical Research (R.R.G.), University of Sydney, and the Departments of Respiratory and Sleep Medicine (R.R.G.) and Neurology (C.S.A.), Royal Prince Alfred Hospital, Sydney Health Partners, Sydney, and the Western Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Perth, WA (N.M., S.M.) - all in Australia; the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease (Y.L., N.Z.), and Guangdong General Hospital and Guangdong Academy of Medical Sciences (Q.O.), Guangzhou, the First Affiliated Hospital of Nanjing Medical University, Nanjing (X.Z.), the Second Affiliated Hospital of Soochow University, Suzhou (R.C.), the Department of Cardiology, Fuwai Hospital (Z.L.), and George Institute for Global Health China (C.S.A.), Peking University Health Sciences Center, Beijing, the Department of Neurology, Xuzhou Central Hospital, Xuzhou (G.C.), Hejian Municipal People's Hospital, Hejian (B.D.), and Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University, Shanghai (J.W.) - all in China; University Hospital of Guadalajara, Guadalajara (O.M.), the Respiratory Department, Institut de Recerca Biomèdica de Lleida, Lleida (F.B.), and Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid (F.B.) - all in Spain; Instituto do Coracao (Incor) and Hospital Universitario (L.F.D., G.L.-F.) and the Hypertension Unit, Renal Division, University of São Paulo Medical Sc

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http://dx.doi.org/10.1056/NEJMoa1606599DOI Listing
September 2016

Comparison of rivaroxaban mono-therapy and standard-therapy adjusted by CYP2C9 and VKORC1 genotypes in symptomatic pulmonary embolism.

Clin Chim Acta 2016 Aug 4;459:25-29. Epub 2016 May 4.

Department of Respiration, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China; Guangzhou Institute of Respiratory Disease & State Key Laboratory of Respiratory Disease, Guangzhou 510120, China; National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00098981163020
Publisher Site
http://dx.doi.org/10.1016/j.cca.2016.05.002DOI Listing
August 2016

Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells.

Sci Rep 2016 08 10;6:31087. Epub 2016 Aug 10.

The State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, and the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.1038/srep31087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978974PMC
August 2016

Omalizumab Improves Quality of Life and Asthma Control in Chinese Patients With Moderate to Severe Asthma: A Randomized Phase III Study.

Allergy Asthma Immunol Res 2016 Jul;8(4):319-28

State Key Laboratory of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.4168/aair.2016.8.4.319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853509PMC
July 2016

Efficacy of delayed treatment of China-made Peramivir with repeated intravenous injections in a mouse influenza model: from clinical experience to basal experiment.

BMC Infect Dis 2016 07 8;16:325. Epub 2016 Jul 8.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated hospital of Guangzhou Medical University, (Guangzhou Medical University), Guangzhou, 510120, People's Republic of China.

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http://dx.doi.org/10.1186/s12879-016-1589-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939023PMC
July 2016

Emergence of triple-subtype reassortants of fatal human H5N6 avian influenza virus in Yunnan, China.

J Infect 2016 06 17;72(6):753-756. Epub 2016 Mar 17.

Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2016.03.005DOI Listing
June 2016

Clinical characteristics and risk factors of pulmonary hypertension associated with chronic respiratory diseases: a retrospective study.

J Thorac Dis 2016 Mar;8(3):350-8

1 State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The Affiliated Hospital of Guangzhou Medical University, Guangdong 510120, China ; 2 Geisinger Medical Center, 100 North Academy Avenue, Danville, USA ; 3 Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, USA.

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http://dx.doi.org/10.21037/jtd.2016.02.58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805801PMC
March 2016

Tracheal nodular lymphoid hyperplasia presenting dyspnea and obstructive sleep apnea.

J Thorac Dis 2016 Mar;8(3):E229-31

1 State Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, 2 Laboratory of ENT-HNS Disease, 3 State Key Laboratory of Respiratory Disease, First Affiliated Hospital, Guangzhou Medical University, Guangzhou 510120, China.

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http://dx.doi.org/10.21037/jtd.2016.03.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805792PMC
March 2016

A Functional Variant rs6435156C > T in BMPR2 is Associated With Increased Risk of Chronic Obstructive Pulmonary Disease (COPD) in Southern Chinese Population.

EBioMedicine 2016 Mar 5;5:167-74. Epub 2016 Feb 5.

State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.1016/j.ebiom.2016.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816816PMC
March 2016

Functional mutations in 5'UTR of the BMPR2 gene identified in Chinese families with pulmonary arterial hypertension.

Pulm Circ 2016 Mar;6(1):103-8

State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1086/685078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860546PMC
March 2016

[Genomics of chronic obstructive pulmonary disease].

Zhonghua Jie He He Hu Xi Za Zhi 2016 Jan;39(1):58-61

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http://dx.doi.org/10.3760/cma.j.issn.1001-0939.2016.01.016DOI Listing
January 2016

[The research progresses of oxidative stress biomarkers in COPD].

Zhonghua Jie He He Hu Xi Za Zhi 2015 Dec;38(12):931-4

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December 2015

[Changes in small airway function in rhinitis without asthma].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2015 Nov;29(21):1864-7

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November 2015