Nancy U Lin

Nancy U Lin

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Nancy U Lin

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Breast cancer subtype and intracranial recurrence patterns after brain-directed radiation for brain metastases.

Breast Cancer Res Treat 2019 Jul 13;176(1):171-179. Epub 2019 Apr 13.

Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

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http://link.springer.com/10.1007/s10549-019-05236-6
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http://dx.doi.org/10.1007/s10549-019-05236-6DOI Listing
July 2019

Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation.

Clin Cancer Res 2019 Jun 18. Epub 2019 Jun 18.

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-0596DOI Listing
June 2019

Correction to: Systemic Therapy of Central Nervous System Metastases of Breast Cancer.

Curr Oncol Rep 2019 May 17;21(7):59. Epub 2019 May 17.

Department of Medical Oncology, Division of Breast Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Ave., Boston, MA, 02215, USA.

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http://link.springer.com/10.1007/s11912-019-0813-3
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http://dx.doi.org/10.1007/s11912-019-0813-3DOI Listing
May 2019

Systemic Therapy of Central Nervous System Metastases of Breast Cancer.

Curr Oncol Rep 2019 Apr 8;21(6):49. Epub 2019 Apr 8.

Department of Medical Oncology, Division of Breast Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Ave., Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s11912-019-0802-6DOI Listing
April 2019

Prognostic Value of Brain Metastasis-Free Interval in Patients with Breast Cancer Brain Metastases.

World Neurosurg 2019 Apr 26. Epub 2019 Apr 26.

Department of Neurosurgery, Computational Neuroscience Outcomes Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Department of Neurosurgery, Leiden University Medical Center, Leiden, Zuid-Holland, the Netherlands; Department of Neurosurgery, Haaglanden Medical Center, The Hague, the Netherlands; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2019.04.072DOI Listing
April 2019

Insights into Molecular Classifications of Triple-Negative Breast Cancer: Improving Patient Selection for Treatment.

Cancer Discov 2019 02 24;9(2):176-198. Epub 2019 Jan 24.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-18-1177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387871PMC
February 2019

Systemic Therapy for Patients With Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: ASCO Clinical Practice Guideline Update.

J Clin Oncol 2018 09 25;36(26):2736-2740. Epub 2018 Jun 25.

Sharon H. Giordano, The University of Texas MD Anderson, Houston; Debra A. Patt, Texas Oncology, Austin, TX; Sarah Temin, American Society of Clinical Oncology, Alexandria, VA; Sarat Chandarlapaty and Shanu Modi, Memorial Sloan Kettering Cancer Center; Francisco J. Esteva, New York University Langone Medical Center, New York; Jeffrey J. Kirshner, Hematology/Oncology Associates of Central New York, East Syracuse, NY; Jennie R. Crews, Seattle Cancer Care Alliance; Nancy E. Davidson, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA; Ian E. Krop, Nancy U. Lin, and Eric P. Winer, Dana-Farber Cancer Institute, Boston, MA; Jennifer Levinson, Ponte Vedra Beach; Naren Ramakrishna, Orlando Health University of Florida Health Cancer Center, Orlando, FL; and Jane Perlmutter, Ann Arbor, MI.

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http://dx.doi.org/10.1200/JCO.2018.79.2697DOI Listing
September 2018

Recommendations on Disease Management for Patients With Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases: ASCO Clinical Practice Guideline Update.

J Clin Oncol 2018 09 25;36(27):2804-2807. Epub 2018 Jun 25.

Naren Ramakrishna, University of Florida Health Cancer Center at Orlando Health, Orlando; Jennifer Levinson, Ponte Vedra Beach, FL; Sarah Temin, American Society of Clinical Oncology, Alexandria, VA; Sarat Chandarlapaty and Shanu Modi, Memorial Sloan Kettering Cancer Center; Francisco J. Esteva, New York University Langone Medical Center, New York; Jeffrey J. Kirshner, Hematology/Oncology Associates of Central New York, East Syracuse, NY; Jennie R. Crews, Seattle Cancer Care Alliance, Seattle, WA; Nancy E. Davidson, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA; Sharon H. Giordano, University of Texas MD Anderson Cancer Center, Houston; Debra A. Patt, Texas Oncology, Austin, TX; Ian E. Krop, Eric P. Winer, and Nancy U. Lin, Dana-Farber Cancer Institute, Boston, MA; and Jane Perlmutter, Ann Arbor, MI.

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http://dx.doi.org/10.1200/JCO.2018.79.2713DOI Listing
September 2018

Increasing Burden of Prior Authorizations in the Delivery of Oncology Care in the United States.

J Oncol Pract 2018 09 20;14(9):525-528. Epub 2018 Aug 20.

Dana-Farber Cancer Institute, Boston, MA; and Marin Cancer Care, Greenbrae, CA.

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http://ascopubs.org/doi/10.1200/JOP.18.00428
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http://dx.doi.org/10.1200/JOP.18.00428DOI Listing
September 2018

Update on managing brain metastases in breast cancer.

Authors:
Nancy U Lin

Clin Adv Hematol Oncol 2018 Sep;16(9):598-601

Harvard Medical School, Boston, Massachusetts.

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September 2018

Recommendations on Disease Management for Patients With Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases: ASCO Clinical Practice Guideline Update Summary.

J Oncol Pract 2018 08 10;14(8):505-507. Epub 2018 Jul 10.

University of Florida Health Cancer Center at Orlando Health, Orlando, FL; American Society of Clinical Oncology, Alexandria, VA; and Dana-Farber Cancer Institute, Boston, MA.

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http://dx.doi.org/10.1200/JOP.18.00291DOI Listing
August 2018

Attitudes of patients with metastatic cancer towards research biopsies.

Asia Pac J Clin Oncol 2018 Jun 6;14(3):231-238. Epub 2017 Nov 6.

University of New South Wales, Kensington, NSW, Australia.

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http://dx.doi.org/10.1111/ajco.12783DOI Listing
June 2018

Breast cancer-specific survival by age: Worse outcomes for the oldest patients.

Cancer 2018 05 2;124(10):2184-2191. Epub 2018 Mar 2.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncr.31308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935594PMC
May 2018

Variation in guideline-concordant care for elderly patients with metastatic breast cancer in the United States.

Breast Cancer Res Treat 2018 Apr 13;168(3):727-737. Epub 2018 Jan 13.

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s10549-018-4659-4DOI Listing
April 2018

Drug Resistance in HER2-Positive Breast Cancer Brain Metastases: Blame the Barrier or the Brain?

Clin Cancer Res 2018 04 6;24(8):1795-1804. Epub 2018 Feb 6.

Department of Cancer Biology, Dana Farber Cancer Institute, Boston, Massachusetts.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-3351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899637PMC
April 2018

Treatment adoption and relative effectiveness of aromatase inhibitors compared to tamoxifen in early breast cancer: A multi-institutional observational study.

Breast 2018 Feb 10;37:107-113. Epub 2017 Nov 10.

Institut Gustave Roussy, Unit INSERM 981, 114 Rue Edouard Vaillant, 94800 Villejuif, France; Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2017.11.003DOI Listing
February 2018

Association of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer.

J Clin Oncol 2018 02 3;36(6):543-553. Epub 2018 Jan 3.

Daniel G. Stover, Ohio State University Comprehensive Cancer Center, Columbus, OH; Heather A. Parsons, Gavin Ha, William T. Barry, Hao Guo, Atish D. Choudhury, Melissa E. Hughes, Deborah A. Dillon, Ann H. Partridge, Nikhil Wagle, Ian E. Krop, Todd R. Golub, Eric P. Winer, Sara M. Tolaney, and Nancy U. Lin, Dana-Farber Cancer Institute; Gad Getz, Massachusetts General Hospital, Boston; Gavin Ha, Samuel S. Freeman, Atish D. Choudhury, Gregory Gydush, Sarah C. Reed, Justin Rhoades, Denisse Rotem, Nikhil Wagle, Gad Getz, Todd R. Golub, and Viktor A. Adalsteinsson, Broad Institute of Harvard and Massachusetts Institute of Technology; and J. Christopher Love, Massachusetts Institute of Technology, Cambridge, MA.

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http://dx.doi.org/10.1200/JCO.2017.76.0033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815405PMC
February 2018

Breast Cancer in the Central Nervous System: Multidisciplinary Considerations and Management.

Am Soc Clin Oncol Educ Book 2017 ;37:45-56

From the Breast Oncology Center, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA; Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO; Department of Neuro-Oncology, University of Turin and City of Health and Science Hospital, Turin, Italy.

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http://dx.doi.org/10.1200/EDBK_175338DOI Listing
December 2017

Modernizing Clinical Trial Eligibility Criteria: Recommendations of the American Society of Clinical Oncology-Friends of Cancer Research Brain Metastases Working Group.

J Clin Oncol 2017 Nov 2;35(33):3760-3773. Epub 2017 Oct 2.

Nancy U. Lin, Dana-Farber Cancer Institute, Boston; Oliver Rosen, Deciphera Pharmaceuticals, Waltham, MA; Tatiana Prowell, Laleh Amiri-Kordestani, and Joohee Sul, US Food and Drug Administration, Silver Spring; Tatiana Prowell, Johns Hopkins Kimmel Cancer Center, Baltimore, MD; Antoinette R. Tan and Edward S. Kim, Carolinas HealthCare System, Charlotte, NC; Marina Kozak, Friends of Cancer Research; Louise Perkins, Melanoma Research Alliance, Washington, DC; Julia White, The Ohio State University, Columbus, OH; Katherine Beal, Memorial Sloan Kettering Cancer Center, New York, NY; and Richard Gaynor, Eli Lilly, Indianapolis, IN.

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http://dx.doi.org/10.1200/JCO.2017.74.0761DOI Listing
November 2017

Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement.

J Clin Oncol 2017 Nov 2;35(33):3737-3744. Epub 2017 Oct 2.

Edward S. Kim, Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC; Suanna S. Bruinooge, Caroline Schenkel, and Richard L. Schilsky, ASCO, Alexandria, VA; Samantha Roberts, Marina Kozak, Jeff Allen, and Ellen Sigal, Friends of Cancer Research; Samantha Roberts, Genentech, Washington, DC; Gwynn Ison, Julia A. Beaver, Rajeshwari Sridhara, and Tatiana M. Prowell, US Food and Drug Administration, Silver Spring; Thomas S. Uldrick and Andrea M. Denicoff, National Cancer Institute, Bethesda, MD; Nancy U. Lin, Dana-Farber Cancer Institute, Boston; Paul J. Hesketh, Lahey Health Cancer Institute, Burlington, MA; Lia Gore, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO; Stuart M. Lichtman, Memorial Sloan-Kettering Cancer Center, New York, NY; Nancy Roach, Fight Colorectal Cancer, Springfield, MO; Elizabeth Garrett-Mayer, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC; Eric Rubin, Merck Research Laboratories, Kenilworth, NJ; and Pratik Multani, Ignyta, San Diego, CA.

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http://dx.doi.org/10.1200/JCO.2017.73.7916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692724PMC
November 2017

Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study.

Neuro Oncol 2017 Oct;19(11):1511-1521

Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts; Department of Biostatistics, Harvard T. H. Chan School of Public Health, and Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts; Department of Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1093/neuonc/nox077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737512PMC
October 2017

Multiplexed Elimination of Wild-Type DNA and High-Resolution Melting Prior to Targeted Resequencing of Liquid Biopsies.

Clin Chem 2017 Oct 5;63(10):1605-1613. Epub 2017 Jul 5.

Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA;

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http://dx.doi.org/10.1373/clinchem.2017.272849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914173PMC
October 2017

Implementation of Surgeon-Initiated Gene Expression Profile Testing (Onco type DX) Among Patients With Early-Stage Breast Cancer to Reduce Delays in Chemotherapy Initiation.

J Oncol Pract 2017 09 31;13(9):e815-e820. Epub 2017 Aug 31.

Dana-Farber Cancer Institute; Dana-Farber/Brigham and Women's Cancer Center; Brigham and Women's Hospital; and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1200/JOP.2017.023788DOI Listing
September 2017

Reply to Garcia J. et al.

Breast 2017 08 11;34:132. Epub 2017 May 11.

Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.breast.2017.05.003DOI Listing
August 2017

Prior Authorization for Medications in a Breast Oncology Practice: Navigation of a Complex Process.

J Oncol Pract 2017 04 28;13(4):e273-e282. Epub 2017 Feb 28.

Dana-Farber Cancer Institute; and Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1200/JOP.2016.017756DOI Listing
April 2017

Monitoring of Serum DNA Methylation as an Early Independent Marker of Response and Survival in Metastatic Breast Cancer: TBCRC 005 Prospective Biomarker Study.

J Clin Oncol 2017 Mar 21;35(7):751-758. Epub 2016 Nov 21.

Kala Visvanathan, Johns Hopkins University School of Medicine and Bloomberg School of Public Health; MaryJo S. Fackler, Zhe Zhang, Zoila A. Lopez-Bujanda, Stacie C. Jeter, Lori J. Sokoll, Leslie M. Cope, Christopher B. Umbricht, David M. Euhus, Saraswati Sukumar, and Antonio C. Wolff, Johns Hopkins University School of Medicine, Baltimore, MD; Elizabeth Garrett-Mayer, Medical University of South Carolina, Charleston, SC; Andres Forero, University of Alabama at Birmingham, Birmingham, AL; Anna M. Storniolo, Indiana University, Bloomington, IN; Rita Nanda, University of Chicago, Chicago, IL; Nancy U. Lin, Dana-Farber Cancer Institute, Boston, MA; Lisa A. Carey, University of North Carolina, Chapel Hill, NC; and James N. Ingle, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1200/JCO.2015.66.2080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455421PMC
March 2017

Patterns of Utilization of Imaging Studies and Serum Tumor Markers Among Patients With De Novo Metastatic Breast Cancer.

J Natl Compr Canc Netw 2017 03;15(3):316-324

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts

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http://dx.doi.org/10.6004/jnccn.2017.0031DOI Listing
March 2017

Imaging in the evaluation and follow-up of early and advanced breast cancer: When, why, and how often?

Breast 2017 Feb 13;31:318-324. Epub 2016 Jul 13.

Dana-Farber Cancer Institute, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2016.06.017DOI Listing
February 2017

Factors Associated With Delays in Chemotherapy Initiation Among Patients With Breast Cancer at a Comprehensive Cancer Center.

J Natl Compr Canc Netw 2016 12;14(12):1519-1526

From Department of Medical Oncology and Quality and Patient Safety, Dana-Farber Cancer Institute, Boston, Massachusetts; Oncoclinicas, Sao Paulo, Brazil; Department of General Surgery, Istanbul Medical School, Istanbul, Turkey; and Department of Surgery, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.6004/jnccn.2016.0163DOI Listing
December 2016

Updates in the management of brain metastases.

Neuro Oncol 2016 08;18(8):1043-65

St. Luke's Radiation Oncology Associates, St. Luke's Cancer Center, Whiteside Institute for Clinical Research and University of Minnesota Duluth, Duluth, Minnesota (N.D.A.); Center for Neuro-Oncology, Dana-Farber/Brigham & Women's Cancer Center, Boston, Massachusetts (E.Q.L., P.Y.W.); Harvard Medical School, Boston, Massachusetts (E.Q.L., B.M.A., N.U.L., I.F.D., P.Y.W.); Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, Maryland (M.P.M.); Department of Medical Oncology, City of Hope, Duarte, California (K.M.); Department of Radiation Oncology, Dana-Farber/Brigham & Women's Cancer Center, Boston, Massachusetts (B.M.A.); Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts (N.U.L.); Department of Medicine, Division of Hematology-Oncology, University of North Carolina, Chapel Hill, North Carolina (C.K.A.); Department of Neurology/Neuro-Oncology, University of Turin, Turin, Italy (R.S.); Division of Medical Oncology, University of Colorado Denver, Denver, Colorado (D.R.C.); Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio (M.A.V.); Department of Neurosurgery, Brigham & Women's Hospital, Boston, Massachusetts (I.F.D.).

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http://dx.doi.org/10.1093/neuonc/now127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933491PMC
August 2016

Treatment of early-stage human epidermal growth factor 2-positive cancers among medicare enrollees: age and race strongly associated with non-use of trastuzumab.

Breast Cancer Res Treat 2016 08 2;159(1):151-62. Epub 2016 Aug 2.

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s10549-016-3927-4DOI Listing
August 2016

Time trends in incidence rates and survival of newly diagnosed stage IV breast cancer by tumor histology: a population-based analysis.

Breast Cancer Res Treat 2016 06 6;157(3):587-96. Epub 2016 Jun 6.

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s10549-016-3845-5DOI Listing
June 2016

Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer.

J Clin Oncol 2016 May 14;34(13):1460-8. Epub 2016 Mar 14.

Nadine Tung, Beth Israel Deaconess Medical Center; Nancy U. Lin, Eric P. Winer, and Judy E. Garber, Dana-Farber Cancer Institute; Nadine Tung, Nancy U. Lin, Eric P. Winer, and Judy E. Garber, Harvard Medical School, Boston, MA; and John Kidd, Brian A. Allen, Nanda Singh, Richard J. Wenstrup, and Anne-Renee Hartman, Myriad Genetic Laboratories, Inc., Salt Lake City, UT.

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http://dx.doi.org/10.1200/JCO.2015.65.0747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872307PMC
May 2016

Randomized trial of a physical activity intervention in women with metastatic breast cancer.

Cancer 2016 Apr 12;122(8):1169-77. Epub 2016 Feb 12.

Breast Oncology Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncr.29899DOI Listing
April 2016

Translational Breast Cancer Research Consortium (TBCRC) 022: A Phase II Trial of Neratinib for Patients With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases.

J Clin Oncol 2016 Mar 1;34(9):945-52. Epub 2016 Feb 1.

Rachel A. Freedman, Rebecca S. Gelman, Christina Herold, Nicole Ryabin, Sarah Farooq, Elizabeth Lawler, Ian E. Krop, Eric P. Winer, and Nancy U. Lin, Dana-Farber Cancer Institute; Beverly Moy, Massachusetts General Hospital; Alarice Lowe and Nathalie Y.R. Agar, Brigham and Women's Hospital, Boston, MA; Jeffrey S. Wefel, Kenneth R. Hess, and Nuhad Ibrahim, The University of Texas MD Anderson Cancer Center; Polly A. Niravath and Mothaffar F. Rimawi, Baylor College of Medicine, Houston, TX; Michelle E. Melisko, University of California, San Francisco, San Francisco, CA; Roisin M. Connolly and Antonio C. Wolff, Johns Hopkins University, Baltimore, MD; Catherine H. Van Poznak, University of Michigan, Ann Arbor, MI; Shannon L. Puhalla, University of Pittsburgh Cancer Institute and Magee-Women's Hospital, Pittsburgh, PA; Kimberly L. Blackwell, Duke University Medical Center, Durham, NC; and Minetta C. Liu, Mayo Clinic, Rochester, MN.

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http://jco.ascopubs.org/content/early/2016/01/28/JCO.2015.63
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2015.63.0343
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http://dx.doi.org/10.1200/JCO.2015.63.0343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070554PMC
March 2016

Variation in Additional Breast Imaging Orders and Impact on Surgical Wait Times at a Comprehensive Cancer Center.

Ann Surg Oncol 2015 Dec 26;22 Suppl 3:S428-34. Epub 2015 Aug 26.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1245/s10434-015-4834-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688062PMC
December 2015

Better treatments needed for breast cancer brain metastases.

Authors:
Nancy U Lin

Lancet Oncol 2015 Dec 17;16(16):1583-4. Epub 2015 Nov 17.

Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)00477-5DOI Listing
December 2015

Variation in the Attitudes of Medical Oncologists Toward Research Biopsies in Patients With Metastatic Breast Cancer.

Oncologist 2015 Sep 3;20(9):992-1000. Epub 2015 Aug 3.

Dana-Farber Cancer Institute, Boston, Massachusetts, USA; Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; Memorial Sloan Kettering Cancer Center, New York, New York, USA; Brigham and Women's Hospital, Boston, Massachusetts, USA; Massachusetts General Hospital, Boston, Massachusetts, USA

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http://dx.doi.org/10.1634/theoncologist.2015-0112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571800PMC
September 2015

Phase II Study of Lapatinib in Combination With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer: Clinical Outcomes and Predictive Value of Early [18F]Fluorodeoxyglucose Positron Emission Tomography Imaging (TBCRC 003).

J Clin Oncol 2015 Aug 13;33(24):2623-31. Epub 2015 Jul 13.

Nancy U. Lin, Hao Guo, Nicole Ryabin, Julie S. Najita, William T. Barry, Ian E. Krop, Eric P. Winer, and Annick D. Van den Abbeele, Dana-Farber Cancer Institute; Andrea L. Richardson and Annick D. Van den Abbeele, Brigham and Women's Hospital, Boston, MA; Jeffrey T. Yap, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT; Ingrid A. Mayer and Carlos L. Arteaga, Vanderbilt-Ingram Cancer Center, Nashville, TN; Carla I. Falkson, University of Alabama, Birmingham, AL; Timothy J. Hobday, Mayo Clinic, Rochester, MN; E. Claire Dees, University of North Carolina, Chapel Hill, NC; Rita Nanda, University of Chicago, Chicago, IL; Mothaffar F. Rimawi, Baylor College of Medicine, Houston, TX; and Antonio C. Wolff, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2014.60.0353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534525PMC
August 2015

Racial differences in outcomes for patients with metastatic breast cancer by disease subtype.

Breast Cancer Res Treat 2015 Jun 29;151(3):697-707. Epub 2015 May 29.

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s10549-015-3432-1DOI Listing
June 2015

Weighing the options for human epidermal growth factor receptor 2-directed therapy in metastatic breast cancer.

Authors:
Nancy U Lin

J Clin Oncol 2015 May 6;33(14):1530-3. Epub 2015 Apr 6.

Dana-Farber Cancer Institute, Boston, MA

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http://dx.doi.org/10.1200/JCO.2014.60.1427DOI Listing
May 2015

Reply to H.L. McArthur et al.

J Clin Oncol 2015 Jan 17;33(1):125. Epub 2014 Nov 17.

Dana-Farber Cancer Institute, Boston, MA

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http://dx.doi.org/10.1200/JCO.2014.58.9655DOI Listing
January 2015

HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models.

Proc Natl Acad Sci U S A 2014 Dec 8;111(51):18297-302. Epub 2014 Dec 8.

Whitehead Institute for Biomedical Research, Cambridge, MA 02142; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142; and Howard Hughes Medical Institute, Cambridge, MA 02142

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http://dx.doi.org/10.1073/pnas.1421323111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280614PMC
December 2014

Understanding process-of-care delays in surgical treatment of breast cancer at a comprehensive cancer center.

Breast Cancer Res Treat 2014 Nov 1;148(1):125-33. Epub 2014 Oct 1.

Department of Surgery, Dana Farber Cancer Institute, 450 Brookline Ave., Boston, MA, 02215, USA,

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http://dx.doi.org/10.1007/s10549-014-3124-2DOI Listing
November 2014

Informational needs and the quality of life of patients in their first year after metastatic breast cancer diagnosis.

J Community Support Oncol 2014 Oct;12(10):347-54

Dana-Farber Cancer Institute, Department of Medical Oncology, Boston, Massachusetts, USA.

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http://dx.doi.org/10.12788/jcso.0077DOI Listing
October 2014

Systemic therapy for patients with advanced human epidermal growth factor receptor 2-positive breast cancer: American Society of Clinical Oncology clinical practice guideline.

J Clin Oncol 2014 Jul 5;32(19):2078-99. Epub 2014 May 5.

Sharon H. Giordano and Ana M. Gonzalez-Angulo, University of Texas MD Anderson Cancer Center, Houston; Debra A. Patt, Texas Oncology, Austin, TX; Sarah Temin, American Society of Clinical Oncology, Alexandria, VA; Jeffrey J. Kirshner, Hematology/Oncology Associates of Central New York, East Syracuse; Sarat Chandarlapaty and Shanu Modi, Memorial Sloan Kettering Cancer Center; Francisco J. Esteva, New York University Cancer Institute, New York, NY; Jennie R. Crews, PeaceHealth St Joseph Cancer Center, Bellingham, WA; Nancy E. Davidson, University of Pittsburgh Cancer Institute and University of Pittsburgh Medical Center Cancer Center, Pittsburgh, PA; Ian Krop, Nancy U. Lin, and Eric P. Winer, Dana-Farber Cancer Institute, Boston, MA; Jennifer Levinson, Ponte Vedra Beach; Edith A. Perez, Mayo Clinic, Jacksonville; Naren Ramakrishna, University of Florida Health Cancer Center at Orlando Health, Orlando, FL; and Jane Perlmutter, Ann Arbor, MI.

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http://dx.doi.org/10.1200/JCO.2013.54.0948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076031PMC
July 2014

Recommendations on disease management for patients with advanced human epidermal growth factor receptor 2-positive breast cancer and brain metastases: American Society of Clinical Oncology clinical practice guideline.

J Clin Oncol 2014 Jul 5;32(19):2100-8. Epub 2014 May 5.

Naren Ramakrishna, University of Florida Health Cancer Center at Orlando Health, Orlando; Edith A. Perez, Mayo Clinic, Jacksonville; Jennifer Levinson, Ponte Vedra Beach, FL; Sarah Temin, American Society of Clinical Oncology, Alexandria, VA; Sarat Chandarlapaty and Shanu Modi, Memorial Sloan Kettering Cancer Center; Francisco J. Esteva, New York University Cancer Institute, New York; Jeffrey J. Kirshner, Hematology/Oncology Associates of Central New York, East Syracuse, NY; Jennie R. Crews, PeaceHealth St Joseph Cancer Center, Bellingham, WA; Nancy E. Davidson, University of Pittsburgh Cancer Institute and University of Pittsburgh Medical Center Cancer Center, Pittsburgh, PA; Sharon H. Giordano and Ana M. Gonzalez-Angulo, University of Texas MD Anderson Cancer Center, Houston; Debra A. Patt, Texas Oncology, Austin, TX; Ian Krop, Eric P. Winter, and Nancy U. Lin, Dana-Farber Cancer Institute, Boston, MA; and Jane Perlmutter, Ann Arbor, MI.

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http://dx.doi.org/10.1200/JCO.2013.54.0955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366342PMC
July 2014

Outcomes by tumor subtype and treatment pattern in women with small, node-negative breast cancer: a multi-institutional study.

J Clin Oncol 2014 Jul 2;32(20):2142-50. Epub 2014 Jun 2.

Ines Vaz-Luis, Melissa E. Hughes, Harold J. Burstein, Jane C. Weeks, Eric P. Winer, and Nancy U. Lin, Dana-Farber Cancer Institute; Beverly Moy, Massachusetts General Hospital, Boston, MA; Ines Vaz-Luis, Instituto de Medicina Molecular, Lisbon, Portugal; Rebecca A. Ottesen and Rizvan Mamet, City of Hope, Duarte; Hope S. Rugo, University of California, San Francisco, San Francisco, CA; Stephen B. Edge, Roswell Park Cancer Institute, Buffalo, NY; Stephen B. Edge, Baptist Cancer Center, Memphis, TN; and Ana M. Gonzalez-Angulo and Richard L. Theriault, University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2013.53.1608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076026PMC
July 2014

Updates on the management of breast cancer brain metastases.

Oncology (Williston Park) 2014 Jul;28(7):572-8

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July 2014

Patterns of chemotherapy, toxicity, and short-term outcomes for older women receiving adjuvant trastuzumab-based therapy.

Breast Cancer Res Treat 2014 Jun 23;145(2):491-501. Epub 2014 Apr 23.

Department of Medical Oncology, Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA,

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http://dx.doi.org/10.1007/s10549-014-2968-9DOI Listing
June 2014

Duration and toxicity of adjuvant trastuzumab in older patients with early-stage breast cancer: a population-based study.

J Clin Oncol 2014 Mar 10;32(9):927-34. Epub 2014 Feb 10.

Ines Vaz-Luis, Nancy U. Lin, Eric P. Winer, and Rachel A. Freedman, Dana-Farber Cancer Institute; Nancy L. Keating, Harvard Medical School; Nancy L. Keating and Huichuan Lii, Brigham and Women's Hospital, Boston, MA; and Ines Vaz-Luis, Instituto de Medicina Molecular, Lisbon, Portugal.

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http://dx.doi.org/10.1200/JCO.2013.51.1261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948095PMC
March 2014

Targeted therapies in brain metastases.

Authors:
Nancy U Lin

Curr Treat Options Neurol 2014 Jan;16(1):276

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA,

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http://dx.doi.org/10.1007/s11940-013-0276-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895218PMC
January 2014

Use and duration of chemotherapy in patients with metastatic breast cancer according to tumor subtype and line of therapy.

J Natl Compr Canc Netw 2014 Jan;12(1):71-80

From the aDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, and bDepartment of Medical Oncology, The Ohio State University College of Medicine, Columbus, Ohio.

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http://dx.doi.org/10.6004/jnccn.2014.0008DOI Listing
January 2014

Voxelwise single-subject analysis of imaging metabolic response to therapy in neuro-oncology.

Stat 2014 Jan;3(1):172-186

Department of Statistics, North Carolina State University, 2311 Stinson Drive, Raleigh, NC 27615.

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http://dx.doi.org/10.1002/sta4.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078880PMC
January 2014

CNS metastases in breast cancer: old challenge, new frontiers.

Clin Cancer Res 2013 Dec;19(23):6404-18

Authors' Affiliations: Dana-Farber Cancer Institute, Boston, Massachusetts; Medical Oncology Branch, Center for Cancer Research, National Cancer Institute; Women's Cancers Section, Laboratory of Molecular Pharmacology; and Biostatistics and Data Management Section, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0790DOI Listing
December 2013

Follow-up after breast cancer diagnosis.

Breast Care (Basel) 2013 Dec;8(6):457-60

Department of Medicine, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1159/000357586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919482PMC
December 2013

Clinical outcomes and treatment practice patterns of patients with HER2-positive metastatic breast cancer in the post-trastuzumab era.

Breast 2013 Aug 23;22(4):525-31. Epub 2013 Jan 23.

Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University College of Medicine, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.breast.2012.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713786PMC
August 2013

Attitudes of patients with metastatic breast cancer toward research biopsies.

Ann Oncol 2013 Jul 13;24(7):1853-9. Epub 2013 Mar 13.

Deparment of Medical Oncology, Dana-Farber Cancer Institute, Boston. MA02215, USA.

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http://dx.doi.org/10.1093/annonc/mdt067DOI Listing
July 2013

Perceptions and needs of women with metastatic breast cancer: a focus on clinical trials.

Breast 2013 Jun 25;22(3):370-3. Epub 2013 Mar 25.

Texas Tech University Health Sciences Center, Paul L. Foster School of Medicine, 4800 Alberta Avenue, El Paso, TX 79905, United States.

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http://dx.doi.org/10.1016/j.breast.2013.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978177PMC
June 2013

Reply to V. Pitini et al.

J Clin Oncol 2013 Jun;31(17):2225-6

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http://dx.doi.org/10.1200/JCO.2012.48.3719DOI Listing
June 2013

Breast cancer brain metastases: new directions in systemic therapy.

Authors:
Nancy U Lin

Ecancermedicalscience 2013 18;7:307. Epub 2013 Apr 18.

Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.3332/ecancer.2013.307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646423PMC
May 2013

Brain metastases in HER2-positive breast cancer.

Authors:
Nancy U Lin

Lancet Oncol 2013 Mar 13;14(3):185-6. Epub 2013 Feb 13.

Division of Women's Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/S1470-2045(13)70046-9DOI Listing
March 2013

Brain metastasis: opportunity for drug development?

Curr Opin Neurol 2012 Dec;25(6):786-94

Department of Medicine I and Comprehensive Cancer Center CNS Unit, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1097/WCO.0b013e328359320dDOI Listing
December 2012