Nancy R Cook

Nancy R Cook

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Nancy R Cook

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Prospectively collected lifestyle and health information as risk factors for white matter hyperintensity volume in stroke patients.

Eur J Epidemiol 2019 Oct 9;34(10):957-965. Epub 2019 Aug 9.

Department of Neurology, J. Philip Kistler Stroke Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s10654-019-00546-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842429PMC
October 2019

Serum 25-hydroxyvitamin D in the VITamin D and OmegA-3 TriaL (VITAL): Clinical and demographic characteristics associated with baseline and change with randomized vitamin D treatment.

Contemp Clin Trials 2019 Oct 24:105854. Epub 2019 Oct 24.

Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Avenue, Boston, MA 02215, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cct.2019.105854DOI Listing
October 2019

Formulas to Estimate Dietary Sodium Intake From Spot Urine Alter Sodium-Mortality Relationship.

Hypertension 2019 09 29;74(3):572-580. Epub 2019 Jul 29.

Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (N.R.C.).

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https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.119.
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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13117DOI Listing
September 2019

Response to: Errors in application of the Kawasaki formula to estimate sodium intake, and false interpretation of data, misclassify the relationship of sodium intake with mortality.

Int J Epidemiol 2019 06;48(3):1019-1020

Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1093/ije/dyz030DOI Listing
June 2019

Statistical methods for building better biomarkers of chronic kidney disease.

Stat Med 2019 May 21;38(11):1903-1917. Epub 2019 Jan 21.

Division of Kidney, Urologic and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1002/sim.8091DOI Listing
May 2019

Marine n-3 Fatty Acids and Vitamin D Supplementation and Primary Prevention. Reply.

N Engl J Med 2019 05;380(19):1879-1880

Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1056/NEJMc1902636DOI Listing
May 2019

Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies.

Authors:
Lisa Pennells Stephen Kaptoge Angela Wood Mike Sweeting Xiaohui Zhao Ian White Stephen Burgess Peter Willeit Thomas Bolton Karel G M Moons Yvonne T van der Schouw Randi Selmer Kay-Tee Khaw Vilmundur Gudnason Gerd Assmann Philippe Amouyel Veikko Salomaa Mika Kivimaki Børge G Nordestgaard Michael J Blaha Lewis H Kuller Hermann Brenner Richard F Gillum Christa Meisinger Ian Ford Matthew W Knuiman Annika Rosengren Debbie A Lawlor Henry Völzke Cyrus Cooper Alejandro Marín Ibañez Edoardo Casiglia Jussi Kauhanen Jackie A Cooper Beatriz Rodriguez Johan Sundström Elizabeth Barrett-Connor Rachel Dankner Paul J Nietert Karina W Davidson Robert B Wallace Dan G Blazer Cecilia Björkelund Chiara Donfrancesco Harlan M Krumholz Aulikki Nissinen Barry R Davis Sean Coady Peter H Whincup Torben Jørgensen Pierre Ducimetiere Maurizio Trevisan Gunnar Engström Carlos J Crespo Tom W Meade Marjolein Visser Daan Kromhout Stefan Kiechl Makoto Daimon Jackie F Price Agustin Gómez de la Cámara J Wouter Jukema Benoît Lamarche Altan Onat Leon A Simons Maryam Kavousi Yoav Ben-Shlomo John Gallacher Jacqueline M Dekker Hisatomi Arima Nawar Shara Robert W Tipping Ronan Roussel Eric J Brunner Wolfgang Koenig Masaru Sakurai Jelena Pavlovic Ron T Gansevoort Dorothea Nagel Uri Goldbourt Elizabeth L M Barr Luigi Palmieri Inger Njølstad Shinichi Sato W M Monique Verschuren Cherian V Varghese Ian Graham Oyere Onuma Philip Greenland Mark Woodward Majid Ezzati Bruce M Psaty Naveed Sattar Rod Jackson Paul M Ridker Nancy R Cook Ralph B D'Agostino Simon G Thompson John Danesh Emanuele Di Angelantonio

Eur Heart J 2019 02;40(7):621-631

Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, UK.

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/eurheartj/ehy653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374687PMC
February 2019

Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease.

N Engl J Med 2019 01 10;380(1):33-44. Epub 2018 Nov 10.

From the Department of Medicine, Brigham and Women's Hospital and Harvard Medical School (J.E.M., N.R.C., I.-M.L., W.C., S.S.B., S.M., H.G., D.G., T.C., D.D., G.F., C.R., V.B., E.L.G., W.C.W., J.E.B.), and the Departments of Epidemiology (J.E.M., N.R.C., I.-M.L., W.C.W., J.E.B.) and Nutrition (E.L.G., W.C.W.), Harvard T.H. Chan School of Public Health - all in Boston.

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http://www.nejm.org/doi/10.1056/NEJMoa1809944
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http://dx.doi.org/10.1056/NEJMoa1809944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425757PMC
January 2019

Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer.

N Engl J Med 2019 01 10;380(1):23-32. Epub 2018 Nov 10.

From the Department of Medicine, Brigham and Women's Hospital and Harvard Medical School (J.E.M., N.R.C., I-M.L., W.C., S.S.B., S.M., H.G., C.M.A., D.G., T.C., D.D., G.F., C.R., V.B., E.L.G., W.C.W., J.E.B.), and the Departments of Epidemiology (J.E.M., N.R.C., I.-M.L., W.C.W., J.E.B.) and Nutrition (E.L.G., W.C.W.), Harvard T.H. Chan School of Public Health - all in Boston.

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http://www.nejm.org/doi/10.1056/NEJMoa1811403
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http://dx.doi.org/10.1056/NEJMoa1811403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392053PMC
January 2019

Weight change and mortality: Long-term results from the trials of hypertension prevention.

J Clin Hypertens (Greenwich) 2018 12 2;20(12):1666-1673. Epub 2018 Nov 2.

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.

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http://doi.wiley.com/10.1111/jch.13418
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http://dx.doi.org/10.1111/jch.13418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289729PMC
December 2018

Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health.

Int J Epidemiol 2018 12;47(6):1784-1795

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1093/ije/dyy114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280933PMC
December 2018

Lipoprotein Particle Profiles, Standard Lipids, and Peripheral Artery Disease Incidence.

Circulation 2018 11;138(21):2330-2341

Division of Preventive Medicine (A.W.A., N.R.C., P.M.R., S.M., A.D.P.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343136PMC
November 2018

Twenty-Four-Hour Diet recall and Diet records compared with 24-hour urinary excretion to predict an individual's sodium consumption: A Systematic Review.

J Clin Hypertens (Greenwich) 2018 10 9;20(10):1360-1376. Epub 2018 Oct 9.

Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1111/jch.13391DOI Listing
October 2018

Meta-analysis of LDL-C Lowering and Mortality.

JAMA 2018 10;320(14):1493

Brigham and Women's Hospital, Boston, Massachusetts.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2018.11202DOI Listing
October 2018

Comparison of Cardiovascular Risk Factors for Coronary Heart Disease and Stroke Type in Women.

J Am Heart Assoc 2018 10;7(19):e007514

1 Center for Cardiovascular Disease Prevention Divisions of Preventive Medicine and Cardiology Brigham and Women's Hospital Harvard Medical School Boston MA.

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https://www.ahajournals.org/doi/10.1161/JAHA.117.007514
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http://dx.doi.org/10.1161/JAHA.117.007514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404882PMC
October 2018

Hypertensive Disorders of Pregnancy and 10-Year Cardiovascular Risk Prediction.

J Am Coll Cardiol 2018 09;72(11):1252-1263

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Division of Women's Health, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183552
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http://dx.doi.org/10.1016/j.jacc.2018.05.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136445PMC
September 2018

Reclassification calibration test for censored survival data: performance and comparison to goodness-of-fit criteria.

Diagn Progn Res 2018 26;2. Epub 2018 Jul 26.

Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave, Brookline MA 02115, (617) 278-0796

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http://dx.doi.org/10.1186/s41512-018-0034-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456068PMC
July 2018

Lipoprotein(a) and Cardiovascular Risk Prediction Among Women.

J Am Coll Cardiol 2018 07 9;72(3):287-296. Epub 2018 Jul 9.

Center for Cardiovascular Disease Prevention, Divisions of Preventive Medicine and Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183481
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http://dx.doi.org/10.1016/j.jacc.2018.04.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277983PMC
July 2018

Quantifying the added value of new biomarkers: how and how not.

Authors:
Nancy R Cook

Diagn Progn Res 2018 11;2:14. Epub 2018 Jul 11.

Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Ave. East, Boston, MA 02215 USA.

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http://dx.doi.org/10.1186/s41512-018-0037-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460632PMC
July 2018

Physical Activity and Incident Cardiovascular Disease in Women: Is the Relation Modified by Level of Global Cardiovascular Risk?

J Am Heart Assoc 2018 06 12;7(12). Epub 2018 Jun 12.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/JAHA.117.008234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220541PMC
June 2018

Lipoprotein insulin resistance score and risk of incident diabetes during extended follow-up of 20 years: The Women's Health Study.

J Clin Lipidol 2017 Sep - Oct;11(5):1257-1267.e2. Epub 2017 Jun 21.

Division of Preventive Medicine, Center for Lipid Metabolomics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Medical School, Boston, MA, USA; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2017.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644504PMC
May 2018

The VITamin D and OmegA-3 TriaL-Depression Endpoint Prevention (VITAL-DEP): Rationale and design of a large-scale ancillary study evaluating vitamin D and marine omega-3 fatty acid supplements for prevention of late-life depression.

Contemp Clin Trials 2018 05 8;68:133-145. Epub 2018 Mar 8.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.cct.2018.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899680PMC
May 2018

Effect of Combined Treatment With Folic Acid, Vitamin B, and Vitamin B on Plasma Biomarkers of Inflammation and Endothelial Dysfunction in Women.

J Am Heart Assoc 2018 05 18;7(11). Epub 2018 May 18.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/JAHA.117.008517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015379PMC
May 2018

Homocysteine, B Vitamins, MTHFR Genotype, and Incident Age-related Macular Degeneration.

Ophthalmol Retina 2018 May;2(5):508-510

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1016/j.oret.2017.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022858PMC
May 2018

Baseline characteristics of participants in the VITamin D and OmegA-3 TriaL (VITAL): Effects on Bone Structure and Architecture.

Contemp Clin Trials 2018 04 23;67:56-67. Epub 2018 Feb 23.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, United States; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S15517144173073
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http://dx.doi.org/10.1016/j.cct.2018.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877816PMC
April 2018

Prospective study of plasma homocysteine, its dietary determinants, and risk of age-related macular degeneration in men.

Ophthalmic Epidemiol 2018 02 16;25(1):79-88. Epub 2017 Oct 16.

a The Division of Preventive Medicine , Department of Medicine, Brigham and Women's Hospital, Harvard Medical School , Boston , MA, USA.

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http://dx.doi.org/10.1080/09286586.2017.1362009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204217PMC
February 2018

Clinical risk reclassification at 10 years.

Stat Med 2017 Dec;36(28):4498-4502

Harvard Medical School, Brigham & Women's Hospital, Boston, MA, 02215, U.S.A.

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http://dx.doi.org/10.1002/sim.7340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726289PMC
December 2017

Assessment of dietary sodium intake using a food frequency questionnaire and 24-hour urinary sodium excretion: a systematic literature review.

J Clin Hypertens (Greenwich) 2017 Dec;19(12):1214-1230

Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1111/jch.13148DOI Listing
December 2017

Randomized Trial of the Effects of Insulin and Metformin on Myocardial Injury and Stress in Diabetes Mellitus: A Post Hoc Exploratory Analysis.

J Am Heart Assoc 2017 12 23;6(12). Epub 2017 Dec 23.

Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1161/JAHA.117.007268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779039PMC
December 2017

Asymptotic distribution of ∆AUC, NRIs, and IDI based on theory of U-statistics.

Stat Med 2017 Sep 19;36(21):3334-3360. Epub 2017 Jun 19.

Department of Mathematics and Statistics, Boston University, 111 Cummington Mall, Boston, MA, 02215, U.S.A.

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http://dx.doi.org/10.1002/sim.7333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931715PMC
September 2017

Modifiable Risk Factors for Incident Heart Failure in Atrial Fibrillation.

JACC Heart Fail 2017 08 14;5(8):552-560. Epub 2017 Jun 14.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jchf.2017.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873947PMC
August 2017

Cholesterol Evaluation in Young Adults: Absence of Clinical Trial Evidence Is Not a Reason to Delay Screening.

Ann Intern Med 2017 06 16;166(12):901-902. Epub 2017 May 16.

From Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.7326/M17-0855DOI Listing
June 2017

Should we reconsider the role of age in treatment allocation for primary prevention of cardiovascular disease?

Eur Heart J 2017 05;38(20):1542-1547

Center for Cardiovascular Disease Prevention, Divisions of Preventive Medicine and Cardiology, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1093/eurheartj/ehw287DOI Listing
May 2017

Serum Sortilin Associates With Aortic Calcification and Cardiovascular Risk in Men.

Arterioscler Thromb Vasc Biol 2017 05 9;37(5):1005-1011. Epub 2017 Mar 9.

From the Center for Interdisciplinary Cardiovascular Sciences (C.G., H.I., J.D.H., M.A., E.A.) and Center for Excellence in Vascular Biology (M.A., E.A.), Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Boston VA Healthcare, Department of Cardiology, MA (C.J.O.); INSERM UMR 1033, University of Lyon, Hôpital Edouard Herriot, Department of Rheumatology and Bone Pathology, France (R.C., P.S.); and Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (N.R.C.).

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http://dx.doi.org/10.1161/ATVBAHA.116.308932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407935PMC
May 2017

Excess Cardiovascular Risk in Women Relative to Men Referred for Coronary Angiography Is Associated With Severely Impaired Coronary Flow Reserve, Not Obstructive Disease.

Circulation 2017 02 14;135(6):566-577. Epub 2016 Nov 14.

From Noninvasive Cardiovascular Imaging Program, Division of Cardiovascular Medicine, Department of Medicine, Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (V.R.T., N.R.S., C.R.F., J.H., R.B., S.D., M.F.D.C.); Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA (L.J.S.); Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Boston, MA (N.R.C.); and Divisions of Nuclear Medicine, Cardiothoracic Imaging, and Cardiovascular Medicine, Departments of Medicine and Radiology, University of Michigan, Ann Arbor (V.L.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.023266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459611PMC
February 2017

Impact of Subclinical Hypothyroidism on Cardiometabolic Biomarkers in Women.

J Endocr Soc 2017 Feb 13;1(2):113-123. Epub 2017 Jan 13.

Center for Lipid Metabolomics, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1210/js.2016-1085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453652PMC
February 2017

Strength Training and the Risk of Type 2 Diabetes and Cardiovascular Disease.

Med Sci Sports Exerc 2017 01;49(1):40-46

1Laboratory of Epidemiology and Population Science, Intramural Research Program of the National Institutes of Health, National Institute on Aging, Bethesda, MD; 2Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; 3Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA; and 4Department of Nutrition, Harvard School of Public Health, Boston, MA.

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http://dx.doi.org/10.1249/MSS.0000000000001063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161704PMC
January 2017

Hemoglobin A levels and risk of sudden cardiac death: A nested case-control study.

Heart Rhythm 2017 01 31;14(1):72-78. Epub 2016 Aug 31.

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Center for Arrhythmia Prevention, Brigham and Women's Hospital, Boston, Massachusetts; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts; Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2016.08.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754013PMC
January 2017

Calibration of the Pooled Cohort Equations for Atherosclerotic Cardiovascular Disease: An Update.

Ann Intern Med 2016 Dec 11;165(11):786-794. Epub 2016 Oct 11.

From Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.7326/M16-1739DOI Listing
December 2016

The Pooled Cohort Equations 3 Years On: Building a Stronger Foundation.

Circulation 2016 12;134(23):1789-1791

From Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024246DOI Listing
December 2016

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease.

N Engl J Med 2016 12 13;375(24):2349-2358. Epub 2016 Nov 13.

From the Center for Human Genetic Research and Cardiology Division, Massachusetts General Hospital (A.V.K., P.N., S.K.), and the Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital (N.R.C., D.I.C., P.M.R.), Boston, and the Program in Medical and Population Genetics, Broad Institute, Cambridge (A.V.K., C.A.E., A.G.B., S.K.) - all in Massachusetts; the Department of Clinical Sciences, Lund University, Malmö, Sweden (I.D., O.M., M.O.-M.); the Cardiovascular Institute, Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai, New York (U.B., R.M., V.F.); Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (D.J.R.); and the University of Texas Health Science Center School of Public Health, Houston (E.B.).

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http://dx.doi.org/10.1056/NEJMoa1605086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338864PMC
December 2016

Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention.

J Am Coll Cardiol 2016 10;68(15):1609-1617

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.

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http://dx.doi.org/10.1016/j.jacc.2016.07.745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098805PMC
October 2016

Adding tests to risk based guidelines: evaluating improvements in prediction for an intermediate risk group.

BMJ 2016 Sep 7;354:i4450. Epub 2016 Sep 7.

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1136/bmj.i4450DOI Listing
September 2016

Comparison of Self-Reported and Accelerometer-Assessed Physical Activity in Older Women.

PLoS One 2015 29;10(12):e0145950. Epub 2015 Dec 29.

Division of Preventive Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145950PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694656PMC
July 2016

Relation of Alanine Aminotransferase Levels to Cardiovascular Events and Statin Efficacy.

Am J Cardiol 2016 Jul 21;118(1):49-55. Epub 2016 Apr 21.

Center for Cardiovascular Disease Prevention, Divisions of Preventive Medicine and Cardiovascular Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2016.04.012DOI Listing
July 2016

Risk of Malignant Cancer Among Women With New-Onset Atrial Fibrillation.

JAMA Cardiol 2016 07;1(4):389-96

Center for Arrhythmia Prevention, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts3Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Ma.

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http://dx.doi.org/10.1001/jamacardio.2016.0280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957657PMC
July 2016

Baseline characteristics of participants in the VITamin D and OmegA-3 TriaL (VITAL).

Contemp Clin Trials 2016 Mar 6;47:235-43. Epub 2016 Jan 6.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, United States; Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, Massachusetts 02115, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cct.2015.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818165PMC
March 2016

How to translate clinical trial results into gain in healthy life expectancy for individual patients.

BMJ 2016 Mar 30;352:i1548. Epub 2016 Mar 30.

Harvard Medical School, Boston, MA, USA; Centre for Cardiovascular Disease Prevention, Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1136/bmj.i1548DOI Listing
March 2016

Environmental Chemicals in Urine and Blood: Improving Methods for Creatinine and Lipid Adjustment.

Environ Health Perspect 2016 Feb 24;124(2):220-7. Epub 2015 Jul 24.

Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1289/ehp.1509693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749084PMC
February 2016

Impact of Modifiable Risk Factors on B-type Natriuretic Peptide and Cardiac Troponin T Concentrations.

Am J Cardiol 2016 Feb 18;117(3):376-81. Epub 2015 Nov 18.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2015.10.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743250PMC
February 2016

Adiposity throughout adulthood and risk of sudden cardiac death in women.

JACC Clin Electrophysiol 2015 Dec;1(6):520-528

Center for Arrhythmia Prevention, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; The Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; The Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.jacep.2015.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725590PMC
December 2015

Identifying an Optimal Cutpoint for the Diagnosis of Hypertriglyceridemia in the Nonfasting State.

Clin Chem 2015 Sep 12;61(9):1156-63. Epub 2015 Jun 12.

Division of Preventive Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;

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http://dx.doi.org/10.1373/clinchem.2015.241752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554926PMC
September 2015

Usefulness of B-type Natriuretic Peptides to Predict Cardiovascular Events in Women (from the Women's Health Study).

Am J Cardiol 2015 Aug 21;116(4):532-7. Epub 2015 May 21.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Division of Cardiovascular Medicine, Department of Medicine, VA Boston Medical Center, West Roxbury, Massachusetts.

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http://dx.doi.org/10.1016/j.amjcard.2015.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586028PMC
August 2015

Tests of calibration and goodness-of-fit in the survival setting.

Stat Med 2015 May 11;34(10):1659-80. Epub 2015 Feb 11.

Division of Preventive Medicine, Brigham and Women's Hospital Harvard Medical School, 900 Commonwealth Ave., East Boston, MA, 02215, U.S.A.

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http://dx.doi.org/10.1002/sim.6428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555993PMC
May 2015

Effect of long-term supplementation with folic acid and B vitamins on risk of depression in older women.

Br J Psychiatry 2015 Apr 8;206(4):324-31. Epub 2015 Jan 8.

Olivia I. Okereke, MD, SM, Channing Division of Network Medicine, Boston, Department of Psychiatry, Brigham and Women's Hospital and Harvard Medical School and Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Nancy R. Cook, ScD, Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School and Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Christine M. Albert, Martin Van Denburgh, Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Julie E. Buring, ScD, JoAnn E. Manson, MD, DrPH, Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School and Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1192/bjp.bp.114.148361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381191PMC
April 2015

Prospective study of plasma homocysteine level and risk of age-related macular degeneration in women.

Ophthalmic Epidemiol 2015 Apr;22(2):85-93

Division of Preventive Medicine, Department of Medicine , Brigham and Women's Hospital, Harvard Medical School, Boston, MA , USA .

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http://dx.doi.org/10.3109/09286586.2015.1012272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363940PMC
April 2015

VITAL-Bone Health: rationale and design of two ancillary studies evaluating the effects of vitamin D and/or omega-3 fatty acid supplements on incident fractures and bone health outcomes in the VITamin D and OmegA-3 TriaL (VITAL).

Contemp Clin Trials 2015 Mar 24;41:259-68. Epub 2015 Jan 24.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, United States; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cct.2015.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380672PMC
March 2015

A proposal to incorporate trial data into a hybrid ACC/AHA algorithm for the allocation of statin therapy in primary prevention.

J Am Coll Cardiol 2015 Mar;65(9):942-8

Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2014.12.028DOI Listing
March 2015

Comparing cardiovascular risk prediction scores.

Ann Intern Med 2015 Feb;162(4):313-4

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http://dx.doi.org/10.7326/M14-2820DOI Listing
February 2015

Further insight into the cardiovascular risk calculator: the roles of statins, revascularizations, and underascertainment in the Women's Health Study.

JAMA Intern Med 2014 Dec;174(12):1964-71

Center for Cardiovascular Disease Prevention, Divisions of Preventive Medicine and Cardiology, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamainternmed.2014.5336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394380PMC
December 2014

Response to letter regarding article, "lower levels of sodium intake and reduced cardiovascular risk".

Circulation 2014 Dec;130(23):e269

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.114.0
Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.114.013280DOI Listing
December 2014

Lifestyle-based prediction model for the prevention of CVD: the Healthy Heart Score.

J Am Heart Assoc 2014 Nov 14;3(6):e000954. Epub 2014 Nov 14.

Department of Nutrition, Harvard School of Public Health, Boston, MA (S.E.C., W.C.W., E.B.R.) Department of Epidemiology, Harvard School of Public Health, Boston, MA (N.R.C., J.A.E.M., W.C.W., E.B.R.) The Channing Division for Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (W.C.W., E.B.R.).

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http://dx.doi.org/10.1161/JAHA.114.000954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338684PMC
November 2014

Sodium and cardiovascular disease.

Authors:
Nancy R Cook

N Engl J Med 2014 11;371(22):2134

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http://dx.doi.org/10.1056/NEJMc1412113DOI Listing
November 2014

Comparison of lifestyle-based and traditional cardiovascular disease prediction in a multiethnic cohort of nonsmoking women.

Circulation 2014 Oct 25;130(17):1466-73. Epub 2014 Aug 25.

From Brigham and Women's Hospital and Harvard Medical School, Boston, MA (N.P.P., J.E.M., P.MR., N.R.C.); School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, NY (M.J.L.); George Washington University School of Medicine, Washington, DC (L.W.M.); Emory University School of Medicine, Atlanta, GA (L.S.P.); and College of Public Health, University of Iowa, Iowa City (J.G.R.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.012069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206581PMC
October 2014

B-type natriuretic peptides improve cardiovascular disease risk prediction in a cohort of women.

J Am Coll Cardiol 2014 Oct 21;64(17):1789-97. Epub 2014 Oct 21.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2014.04.089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294182PMC
October 2014

Lower levels of sodium intake and reduced cardiovascular risk.

Circulation 2014 Mar 10;129(9):981-9. Epub 2014 Jan 10.

Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (N.R.C.); Welch Center for Prevention, Epidemiology, and Clinical Research, The Johns Hopkins School of Medicine, Baltimore, MD (L.J.A.); and Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (P.K.W.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.113.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.006032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181831PMC
March 2014

Refining the American guidelines for prevention of cardiovascular disease - Authors' reply.

Lancet 2014 Feb;383(9917):600

Center for Cardiovascular Disease Prevention, Divisions of Preventive Medicine and Cardiology, Brigham and Women's Hospital, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/S0140-6736(14)60216-6DOI Listing
February 2014

Cardiovascular disease risk prediction in women: is there a role for novel biomarkers?

Clin Chem 2014 Jan 7;60(1):88-97. Epub 2013 Oct 7.

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1373/clinchem.2013.202796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877731PMC
January 2014

Response to Comment on the reports of over-estimation of ASCVD risk using the 2013 AHA/ACC risk equation.

Circulation 2014 Jan 11;129(2):268-9. Epub 2013 Dec 11.

Center for Cardiovascular Disease Prevention, Divisions of Preventive Medicine and Cardiology, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.007680DOI Listing
January 2014

Statins: new American guidelines for prevention of cardiovascular disease.

Lancet 2013 Nov 20;382(9907):1762-5. Epub 2013 Nov 20.

Center for Cardiovascular Disease Prevention, Divisions of Preventive Medicine and Cardiology, Brigham and Women's Hospital, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(13)62388-0DOI Listing
November 2013

Seafood types and age-related cognitive decline in the Women's Health Study.

J Gerontol A Biol Sci Med Sci 2013 Oct 3;68(10):1255-62. Epub 2013 Apr 3.

SM, Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Ave, Boston, MA 02115.

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http://dx.doi.org/10.1093/gerona/glt037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779629PMC
October 2013

Childhood Blood Pressure Trends and Risk Factors for High Blood Pressure: The NHANES Experience 1988-2008.

Hypertension 2013 Oct 14. Epub 2013 Oct 14.

Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02128DOI Listing
October 2013

Novel genetic markers improve measures of atrial fibrillation risk prediction.

Eur Heart J 2013 Aug 26;34(29):2243-51. Epub 2013 Feb 26.

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/eurheartj/eht033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730133PMC
August 2013

Childhood blood pressure trends and risk factors for high blood pressure: the NHANES experience 1988-2008.

Hypertension 2013 Aug 15;62(2):247-54. Epub 2013 Jul 15.

Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769135PMC
August 2013

Mediterranean diet and cognitive function in older age.

Epidemiology 2013 Jul;24(4):490-9

Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1097/EDE.0b013e318294a065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674216PMC
July 2013

Vitamin D and cancer: can we believe the evidence from observational studies?

Authors:
Nancy R Cook

Clin Chem 2013 May 15;59(5):726-8. Epub 2013 Mar 15.

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http://dx.doi.org/10.1373/clinchem.2013.203158DOI Listing
May 2013