Publications by authors named "Nan-Chen Hsieh"

16 Publications

  • Page 1 of 1

Factors Influencing Self-Efficacy and Self-Management among Patients with Pre-End-Stage Renal Disease (Pre-ESRD).

Healthcare (Basel) 2021 Mar 2;9(3). Epub 2021 Mar 2.

Department of Information Management, National Taipei University of Nursing and Health Sciences, Taipei 112, Taiwan.

Aim: Chronic kidney disease (CKD) is an emerging major public health issue that leads to end-stage kidney disease (ESRD). Factors influencing the self-management and self-efficacy of ESRD patients are still under investigation. The objective of this study is to evaluate the association of depression and anxiety with self-management and self-efficacy in patients with pre-ESRD.

Methods: Patients in the department of nephrology of a regional hospital in Taiwan were invited to participate and were included in our study if they had a confirmed diagnosis of early-stage CKD, were more than 20 years old, and could converse in Mandarin Chinese or Taiwanese. Patients diagnosed with depression, who could not execute self-care, or who had cognitive deficits were excluded. In total, this cross-sectional study included 112 pre-ESRD patients. We used the Chinese versions of the hospital anxiety and depression scale (HADS), the chronic kidney disease self-efficacy instrument (CKD-SE), and the chronic kidney disease self-management instrument (CKD-SM) as the questionnaire. Spearman's rank correlation and logistic regressions were used to analyze the data.

Results: The top quartile of self-management and self-efficacy scores (28 patients) was defined as high self-management and -efficacy, respectively, and the lower three quartiles as low self-management and -efficacy. The logistic regression analysis showed that having depression decreased the odds of having high self-management by 75.4% and high self-efficacy by 75.1%. Having an education level of senior high school or above increased the odds ratios for having high self-management and high self-efficacy to 4.47 and 3.56 (all p-values < 0.05).

Conclusion: Controlling depression as well as increasing the level of education can potentially increase self-management and self-efficacy in pre-ESRD patients.
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http://dx.doi.org/10.3390/healthcare9030266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000963PMC
March 2021

Injection of Lidocaine Alone versus Lidocaine plus Dexmedetomidine in Impacted Third Molar Extraction Surgery, a Double-Blind Randomized Control Trial for Postoperative Pain Evaluation.

Pain Res Manag 2021 25;2021:6623792. Epub 2021 Jan 25.

Department of Information Management, National Taipei University of Nursing and Health Sciences, Taipei City 112, Taiwan.

Objectives: Administration of medications such as dexmedetomidine as a topical anesthetic has been suggested in the pain control in dentistry. This double-blind randomized control trial study evaluated postoperative pain and associated factors following impacted third molar extraction surgery. Lidocaine alone was taken as the control and lidocaine plus dexmedetomidine as the intervention.

Materials And Methods: Forty patients undergoing mandibular third molar extraction entered the study and were randomly allocated to the control and interventional groups. 0.15 ml of dexmedetomidine was added to each lidocaine cartridge and the drug concentration was adjusted to 15 g for the intervention group while only lidocaine was used in the control group. A visual analog scale was used to measure and record pain levels at the end of the surgery and 6, 12, and 24 hours after the surgery and number of painkillers taken by the patients after the surgery was also recorded.

Results: Pain scores of the intervention group decreased significantly during the surgery and also 6, 12, and 24 hours after the surgery compared to the control group. The pain score was correlated significantly with our intervention during the surgery and also 6 and 12 hours after that (all  value < 0.05). There was a nonsignificant reduction in the number of painkillers taken by the patients at 6, 12, and 24 hours after surgery (all  value > 0.05).

Conclusion: In patients undergoing molar surgery, administration of a combination of dexmedetomidine and lidocaine is beneficial for the pain control. Compared to the injection of lidocaine alone, combination of dexmedetomidine and lidocaine can be used for a better pain control in molar surgeries.
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http://dx.doi.org/10.1155/2021/6623792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857915PMC
January 2021

Association of Testosterone-Related Dietary Pattern with Testicular Function among Adult Men: A Cross-Sectional Health Screening Study in Taiwan.

Nutrients 2021 Jan 18;13(1). Epub 2021 Jan 18.

Research Center for Healthcare Industry Innovation, National Taipei University of Nursing and Health Sciences, 365 Ming-Te Road, Beitou District, Taipei 112, Taiwan.

Diets could play an important role in testicular function, but studies on how adherence to the dietary patterns influences human testicular function in Asian countries are scarce. Herein, we examined the association between testosterone-related dietary patterns and testicular function among adult men in Taiwan. This cross-sectional study recruited 3283 men who attended a private medical screening program from 2009 to 2015. Testosterone-related dietary pattern was generated by the reduced rank regression (RRR) method. The association between adherence to quartile of dietary pattern scores with sex hormones (testosterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2)) and sperm quality (sperm concentration (SC), total sperm motility (TSM), progressive motility (PRM), and normal sperm morphology (NSM)) were examined by multivariable linear regression. Hemoglobin (β = 0.57, < 0.001), hematocrit (β = 0.17, = 0.002), triglyceride (β = -0.84, < 0.001), HDL-cholesterol (β = 3.58, < 0.001), total cholesterol to HDL-cholesterol ratio (β = -0.78, < 0.001), and uric acid (β = -10.77, < 0.001) were highly correlated with testosterone levels. Therefore, these biomarkers were used to construct a testosterone-related dietary pattern. Highest adherence (Q4) to dietary pattern scores were negatively associated with lower testosterone in the pooled analysis (β = -0.89, = 0.037) and normal-weight men (β = -1.48, = 0.019). Likewise, men in the Q4 of the dietary pattern had lower SC (β = -5.55, = 0.001) and NSM (β = -2.22, = 0.007) regardless of their nutritional status. Our study suggesting that testosterone-related dietary pattern (rich in preserved vegetables or processed meat or fish, deep-fried foods, innards organs, rice or flour products cooked in oil, and dipping sauce, but low in milk, dairy products, legumes, or beans, and dark or leafy vegetables) was associated with a poor testicular function.
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http://dx.doi.org/10.3390/nu13010259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830687PMC
January 2021

Histological and Radiological Evaluation of Low-Intensity Pulsed Ultrasound Versus Whole Body Vibration on Healing of Mandibular Bone Defects in Rats.

Medicina (Kaunas) 2020 Sep 8;56(9). Epub 2020 Sep 8.

Research Center for Healthcare Industry Innovation, National Taipei University of Nursing and Health Sciences, Taipei City 112, Taiwan.

: Mechanical stimulation can improve the structural properties of the fracture site and induce the differentiation of different cell types for bone regeneration. This study aimed to compare the effect of low-intensity pulsed ultrasound stimulation (LIPUS) versus whole body vibration (WBV) on healing of mandibular bone defects. : A mandibular defect was created in 66 rats. The rats were randomly divided into two groups of rats. Each group was subdivided randomly by three groups ( = 11) as follows: (I) control group, (II) treatment with LIPUS, and (III) treatment with WBV. The radiographic changes in bone density, the ratio of lamellar bone to the entire bone volume, the ratio of the newly formed bone to the connective tissue and inflammation grade were evaluated after 1 and 2 months. : LIPUS significantly increased the radiographic bone density change compared to the control group at the first and second month postoperatively ( < 0.01). WBV only significantly increased the bone density compared to the control group at the second month after the surgery ( < 0.01). : Application of LIPUS and WBV may enhance the regeneration of mandibular bone defects in rats. Although LIPUS and WBV are effective in mandibular bone healing, the effects of LIPUS are faster and greater than WBV.
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http://dx.doi.org/10.3390/medicina56090457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558129PMC
September 2020

The correct formula to calculate triglyceride-glucose index (TyG).

J Pediatr Endocrinol Metab 2020 07;33(7):945-946

College of Nursing, School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, Taiwan.

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http://dx.doi.org/10.1515/jpem-2019-0579DOI Listing
July 2020

Is the use of triglyceride-glucose (TyG) index to recognize glucose disorders really practical?

Eur J Pediatr 2020 07 15;179(7):1169. Epub 2020 May 15.

College of Nursing, School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, 112, Taiwan.

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http://dx.doi.org/10.1007/s00431-020-03642-3DOI Listing
July 2020

Letter to the editor about "Value of triglyceride-glucose index for the estimation of ischemic stroke risk: Insights from a general population".

Nutr Metab Cardiovasc Dis 2020 06 27;30(6):1044-1045. Epub 2020 Mar 27.

College of Nursing, School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei 112, Taiwan.

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http://dx.doi.org/10.1016/j.numecd.2020.02.005DOI Listing
June 2020

Prophylactic anticoagulant therapy for reducing the risk of stroke and other thrombotic events in COVID-19 patients.

J Formos Med Assoc 2020 07 11;119(7):1230-1231. Epub 2020 May 11.

College of Nursing, School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, 112, Taiwan.

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http://dx.doi.org/10.1016/j.jfma.2020.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211643PMC
July 2020

Using the Cardio-Ankle Vascular Index (CAVI) or the Mathematical Correction Form (CAVI) in Clinical Practice.

Int J Mol Sci 2020 Mar 31;21(7). Epub 2020 Mar 31.

Research Center for Healthcare Industry Innovation, National Taipei University of Nursing and Health Sciences, Taipei City 112, Taiwan.

Tonhajzerova et al [...].
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http://dx.doi.org/10.3390/ijms21072410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178179PMC
March 2020

Use of the triglyceride-glucose index (TyG) in cardiovascular disease patients.

Cardiovasc Diabetol 2020 01 15;19(1). Epub 2020 Jan 15.

College of Nursing, School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, 112, Taiwan.

Da Silva et al. showed that the triglyceride-glucose (TyG) index was positively associated with a higher prevalence of symptomatic coronary artery disease (CAD). TyG has been used in healthy individuals as a marker of insulin resistance. The use of this index as a marker of atherosclerosis in cardiovascular disease (CVD) patients might be influenced by diabetes and the hyperlipidemic state that led to CVD. Certain considerations might be necessary before we conclude that the TyG index can be used as a marker of atherosclerosis in CVD patients. These factors can highlight the role of fasting blood glucose and triglyceride levels that are used in the TyG formula. Comparing the fasting blood glucose and/or triglyceride levels with the TyG index in these patients to show how much value the TyG index can add to clinical practice seems to be necessary. Conclusions of such studies might be biased by these facts. Stratification by CAD disease category cannot help achieve an understanding of the role of TyG in CVD. Correlations do not imply causation, so the use of the TyG index as an index in CAD patients is questionable.
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http://dx.doi.org/10.1186/s12933-019-0982-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963998PMC
January 2020

Comment on Lecca, L.I.; Portoghese, I.; Mucci, N.; Galletta, M.; Meloni, F.; Pilia, I.; Marcias, G.; Fabbri, D.; Fostinelli, J.; Lucchini, R.G.; Cocco, P.; Campagna, M. Association between Work-Related Stress and QT Prolongation in Male Workers. 2019, , 4781.

Int J Environ Res Public Health 2020 01 10;17(2). Epub 2020 Jan 10.

Research Center for Healthcare Industry Innovation, National Taipei University of Nursing and Health Sciences, Taipei City 112, Taiwan.

Lecca et al., in a recent publication in the had made some mistakes in the statistical analysis and interpretation of the results. Age was not a clear contributing factor in the prolongation of QT interval in the electrocardiogram (ECG), as there were strong confounders in their study. The effects of age were mainly faded out because of the age range of the participants. The use of Pearson's correlation is questionable because of the normality assumptions was not met on the studied variables. They also made some conclusions about the effects of long and night shifts on the QT prolongation that were not appropriate based on their study type. All of these mentioned issues might completely change the validity of the conclusions they made.
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http://dx.doi.org/10.3390/ijerph17020461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013602PMC
January 2020

Association of Kidney Function Tests with a Cardio-Ankle Vascular Index in Community-Dwelling Individuals with a Normal or Mildly Decreased Estimated Glomerular Filtration Rate.

Medicina (Kaunas) 2019 Sep 29;55(10). Epub 2019 Sep 29.

Research Center For Healthcare Industry Innovation, National Taipei University of Nursing and Health Sciences, Taipei City 112, Taiwan.

: Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease (CVD). Previous studies reported controversial results about the independence of CKD as a risk factor for atherosclerosis. In this study, we tried to determine whether the estimated glomerular filtration rate (eGFR) and other renal function tests are independent factors associated with arterial stiffness in community-dwelling individuals with a normal (≥90) or slightly decreased eGFR (60-90). : Data of 164 community individuals were analyzed, and demographic information, related disease history, atherosclerosis risk factors, certain laboratory tests, the estimated eGFR, and urine albumin creatinine ratio (UACR) were recorded for each individual. : The age, systolic blood pressure (SBP), hypertension (HTN), and cardio-ankle vascular index (CAVI) significantly differed between individuals with a normal and those with a slightly decreased eGFR. Blood urea nitrogen (BUN), glycated hemoglobin (HBA1c), and the eGFR significantly differed between the high- and low-CAVI groups and were also significantly correlated with the CAVI. The relationship between the eGFR and CAVI was shown to be independent of other atherosclerosis risk factors in a multiple linear regression model. : We concluded that evaluations of the eGFR, HTN, body-mass index, and SBP can be used in a model for arterial stiffness risk assessments for community-dwelling individuals with a normal or slightly decreased eGFR.
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http://dx.doi.org/10.3390/medicina55100657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843344PMC
September 2019

Self-Management Programs on eGFR, Depression, and Quality of Life among Patients with Chronic Kidney Disease: A Meta-Analysis.

Asian Nurs Res (Korean Soc Nurs Sci) 2016 Dec 13;10(4):255-262. Epub 2016 May 13.

Department of Long Term Care, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.

Purpose: Chronic kidney disease (CKD) is a condition characterized by the gradual loss of kidney function over time. Self-management programs have been widely applied to chronic disease education programs, which are designed to delay deteriorating kidney functions, preclude depression, and improve quality of life. This study aims to analyze effectiveness of self-management programs in bettering CKD patients' eGFR, mitigating depression symptoms and improving quality of life in randomized control or clinical trials.

Methods: Using key terms, a search was conducted in English-language, peer-reviewed journals on CKD that were published between 2002 and 2014 on databases including CINAHL, Cochrane Library, MEDLINE. The measurable variables included CKD patients' eGFR, depression, and quality of life. Random and fixed effects meta analysis were applied with standard error and correlation based measure of effect size.

Results: Eight studies met the inclusion criteria. A self-management program significantly impacted CKD patients' depression and mental quality-of-life dimensions, with an effect size of .29 [95% confidence interval (CI) (0.07, 0.53)] and -.42 [95% CI (-0.75, -0.10)]. However, the intervention of a self-management program had no significant effect on patients' eGFR as well as physical quality-of-life dimensions, with effect sizes of .06 [95% CI (-0.69, 0.81)] and -.16 [95% CI (-0.81, 0.50)].

Conclusions: Self-management programs of patients with chronic kidney disease can improve the depression and mental quality of life. Aside from providing more objective evidence-based results, this study provides a reference for clinical health care personnel who tend to patients with CKD.
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http://dx.doi.org/10.1016/j.anr.2016.04.002DOI Listing
December 2016

Prediction of self-care behaviour on the basis of knowledge about chronic kidney disease using self-efficacy as a mediator.

J Clin Nurs 2016 Sep 1;25(17-18):2609-18. Epub 2016 Jul 1.

Department of Long-TermCare, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.

Aims And Objectives: This study was to investigate: (1) the important factors in the self-care of chronic kidney disease (CKD) patients and (2) the mediating effects of self-efficacy on knowledge and self-care.

Background: Chronic kidney disease has become a major global health issue and is one of the top 10 leading causes of death in Taiwan where the dialysis population ranks first in the world. The number of patients with poor self-care behaviours continues to rise despite ongoing health education. Knowledge and self-efficacy are important factors that influence self-care behaviour; however, very few articles have examined the relationships among them.

Design: Cross-sectional and correlational design.

Methods: Subject recruitment was conducted by purposive sampling in the renal outpatient clinics and dialysis centres of two teaching hospitals in northern Taiwan. A total of 247 patients with chronic kidney disease (stages 1-5) were enrolled.

Results: (1) Knowledge was positively correlated with self-efficacy (r = 0·41, p < 0·01) and with self-care (r = 0·18, p < 0·01). Self-efficacy (r = 0·44, p < 0·01) as well as age (r = 0·15, p < 0·01) were positively correlated with self-care. (2) The relationship between knowledge and self-care was fully mediated by self-efficacy (z = 4·82, p < 0·001) and the effect was 50%.

Conclusion: The results showed that self-efficacy was a crucial mediator between knowledge and self-care. In addition to providing knowledge to chronic kidney disease patients, healthcare professionals should also offer strategies that can enhance self-efficacy to increase self-care behaviours in chronic kidney disease patients and implement effective disease management.

Relevance To Clinical Practice: Incorporate self-efficacy strategies into the process of health education to improve knowledge and the effectiveness of self-care. The findings of this study provide evidence of effectiveness of the use of group activity through self-management and self-efficacy enhancement programmes and may influence the policy makers to consider adding or modifying the reimbursement criteria.
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http://dx.doi.org/10.1111/jocn.13305DOI Listing
September 2016

Intelligent postoperative morbidity prediction of heart disease using artificial intelligence techniques.

J Med Syst 2012 Jun 24;36(3):1809-20. Epub 2010 Dec 24.

Department of Information Management, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.

Endovascular aneurysm repair (EVAR) is an advanced minimally invasive surgical technology that is helpful for reducing patients' recovery time, postoperative morbidity and mortality. This study proposes an ensemble model to predict postoperative morbidity after EVAR. The ensemble model was developed using a training set of consecutive patients who underwent EVAR between 2000 and 2009. All data required for prediction modeling, including patient demographics, preoperative, co-morbidities, and complication as outcome variables, was collected prospectively and entered into a clinical database. A discretization approach was used to categorize numerical values into informative feature space. Then, the Bayesian network (BN), artificial neural network (ANN), and support vector machine (SVM) were adopted as base models, and stacking combined multiple models. The research outcomes consisted of an ensemble model to predict postoperative morbidity after EVAR, the occurrence of postoperative complications prospectively recorded, and the causal effect knowledge by BNs with Markov blanket concept.
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http://dx.doi.org/10.1007/s10916-010-9640-7DOI Listing
June 2012

Technological innovations in the development of cardiovascular clinical information systems.

J Med Syst 2012 Apr 23;36(2):965-78. Epub 2010 Jul 23.

Department of Information Management, National Taipei University of Nursing and Health Sciences, Taiwan, Republic of China.

Recent studies have shown that computerized clinical case management and decision support systems can be used to assist surgeons in the diagnosis of disease, optimize surgical operation, aid in drug therapy and decrease the cost of medical treatment. Therefore, medical informatics has become an extensive field of research and many of these approaches have demonstrated potential value for improving medical quality. The aim of this study was to develop a web-based cardiovascular clinical information system (CIS) based on innovative techniques, such as electronic medical records, electronic registries and automatic feature surveillance schemes, to provide effective tools and support for clinical care, decision-making, biomedical research and training activities. The CIS developed for this study contained monitoring, surveillance and model construction functions. The monitoring layer function provided a visual user interface. At the surveillance and model construction layers, we explored the application of model construction and intelligent prognosis to aid in making preoperative and postoperative predictions. With the use of the CIS, surgeons can provide reasonable conclusions and explanations in uncertain environments.
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http://dx.doi.org/10.1007/s10916-010-9561-5DOI Listing
April 2012