Publications by authors named "Najim Lahrouchi"

24Publications

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls.

Authors:
Roddy Walsh Najim Lahrouchi Rafik Tadros Florence Kyndt Charlotte Glinge Pieter G Postema Ahmad S Amin Eline A Nannenberg James S Ware Nicola Whiffin Francesco Mazzarotto Doris Škorić-Milosavljević Christian Krijger Elena Arbelo Dominique Babuty Hector Barajas-Martinez Britt M Beckmann Stéphane Bézieau J Martijn Bos Jeroen Breckpot Oscar Campuzano Silvia Castelletti Candan Celen Sebastian Clauss Anniek Corveleyn Lia Crotti Federica Dagradi Carlo de Asmundis Isabelle Denjoy Sven Dittmann Patrick T Ellinor Cristina Gil Ortuño Carla Giustetto Jean-Baptiste Gourraud Daisuke Hazeki Minoru Horie Taisuke Ishikawa Hideki Itoh Yoshiaki Kaneko Jørgen K Kanters Hiroki Kimoto Maria-Christina Kotta Ingrid P C Krapels Masahiko Kurabayashi Julieta Lazarte Antoine Leenhardt Bart L Loeys Catarina Lundin Takeru Makiyama Jacques Mansourati Raphaël P Martins Andrea Mazzanti Stellan Mörner Carlo Napolitano Kimie Ohkubo Michael Papadakis Boris Rudic Maria Sabater Molina Frédéric Sacher Hatice Sahin Georgia Sarquella-Brugada Regina Sebastiano Sanjay Sharma Mary N Sheppard Keiko Shimamoto M Benjamin Shoemaker Birgit Stallmeyer Johannes Steinfurt Yuji Tanaka David J Tester Keisuke Usuda Paul A van der Zwaag Sonia Van Dooren Lut Van Laer Annika Winbo Bo G Winkel Kenichiro Yamagata Sven Zumhagen Paul G A Volders Steven A Lubitz Charles Antzelevitch Pyotr G Platonov Katja E Odening Dan M Roden Jason D Roberts Jonathan R Skinner Jacob Tfelt-Hansen Maarten P van den Berg Morten S Olesen Pier D Lambiase Martin Borggrefe Kenshi Hayashi Annika Rydberg Tadashi Nakajima Masao Yoshinaga Johan B Saenen Stefan Kääb Pedro Brugada Tomas Robyns Daniela F Giachino Michael J Ackerman Ramon Brugada Josep Brugada Juan R Gimeno Can Hasdemir Pascale Guicheney Silvia G Priori Eric Schulze-Bahr Naomasa Makita Peter J Schwartz Wataru Shimizu Takeshi Aiba Jean-Jacques Schott Richard Redon Seiko Ohno Vincent Probst Elijah R Behr Julien Barc Connie R Bezzina

Genet Med 2020 Sep 7. Epub 2020 Sep 7.

Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.1038/s41436-020-00946-5DOI Listing
September 2020

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome.

Authors:
Najim Lahrouchi Rafik Tadros Lia Crotti Yuka Mizusawa Pieter G Postema Leander Beekman Roddy Walsh Kanae Hasegawa Julien Barc Marko Ernsting Kari L Turkowski Andrea Mazzanti Britt M Beckmann Keiko Shimamoto Ulla-Britt Diamant Yanushi D Wijeyeratne Yu Kucho Tomas Robyns Taisuke Ishikawa Elena Arbelo Michael Christiansen Annika Winbo Reza Jabbari Steven A Lubitz Johannes Steinfurt Boris Rudic Bart Loeys M Ben Shoemaker Peter E Weeke Ryan Pfeiffer Brianna Davies Antoine Andorin Nynke Hofman Federica Dagradi Matteo Pedrazzini David J Tester J Martijn Bos Georgia Sarquella-Brugada Óscar Campuzano Pyotr G Platonov Birgit Stallmeyer Sven Zumhagen Eline A Nannenberg Jan H Veldink Leonard H van den Berg Ammar Al-Chalabi Christopher E Shaw Pamela J Shaw Karen E Morrison Peter M Andersen Martina Müller-Nurasyid Daniele Cusi Cristina Barlassina Pilar Galan Mark Lathrop Markus Munter Thomas Werge Marta Ribasés Tin Aung Chiea C Khor Mineo Ozaki Peter Lichtner Thomas Meitinger J Peter van Tintelen Yvonne Hoedemaekers Isabelle Denjoy Antoine Leenhardt Carlo Napolitano Wataru Shimizu Jean-Jacques Schott Jean-Baptiste Gourraud Takeru Makiyama Seiko Ohno Hideki Itoh Andrew D Krahn Charles Antzelevitch Dan M Roden Johan Saenen Martin Borggrefe Katja E Odening Patrick T Ellinor Jacob Tfelt-Hansen Jonathan R Skinner Maarten P van den Berg Morten Salling Olesen Josep Brugada Ramón Brugada Naomasa Makita Jeroen Breckpot Masao Yoshinaga Elijah R Behr Annika Rydberg Takeshi Aiba Stefan Kääb Silvia G Priori Pascale Guicheney Hanno L Tan Christopher Newton-Cheh Michael J Ackerman Peter J Schwartz Eric Schulze-Bahr Vincent Probst Minoru Horie Arthur A Wilde Michael W T Tanck Connie R Bezzina

Circulation 2020 Jul 20;142(4):324-338. Epub 2020 May 20.

Amsterdam UMC, University of Amsterdam, Heart Center; Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, The Netherlands (N.L., R.T., Y.M., P.G.P., L.B., R.W., N.H., H.L.T., A.A.W., C.R.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.045956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382531PMC
July 2020

Genome-wide association studies of cardiac electrical phenotypes.

Cardiovasc Res 2020 Jul;116(9):1620-1634

Department of Clinical and Experimental Cardiology, Amsterdam University Medical Center, University of Amsterdam, Heart Center, Amsterdam Cardiovascular Sciences, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvaa144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341169PMC
July 2020

Predicting Risk for Adult-Onset Sudden Cardiac Death in the Population.

J Am Coll Cardiol 2019 11 11;74(21):2635-2637. Epub 2019 Nov 11.

Amsterdam University Medical Center, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands. Electronic address: https://twitter.com/NajimLahrouchi.

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http://dx.doi.org/10.1016/j.jacc.2019.09.024DOI Listing
November 2019

Predicting cardiac electrical response to sodium-channel blockade and Brugada syndrome using polygenic risk scores.

Eur Heart J 2019 10;40(37):3097-3107

Department of Clinical and Experimental Cardiology, Amsterdam UMC, University of Amsterdam, Heart Center, Amsterdam Cardiovascular Sciences, Meibergdreef 9, AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/eurheartj/ehz435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769824PMC
October 2019

Blood Pressure-Associated Genetic Variants in the Natriuretic Peptide Receptor 1 Gene Modulate Guanylate Cyclase Activity.

Circ Genom Precis Med 2019 08 20;12(8):e002472. Epub 2019 Aug 20.

Center for Genomic Medicine (N.L., C.N.-C.), Massachusetts General Hospital Research Institute and Harvard Medical School, Boston.

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http://dx.doi.org/10.1161/CIRCGEN.119.002472DOI Listing
August 2019

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

Authors:
Ayush Giri Jacklyn N Hellwege Jacob M Keaton Jihwan Park Chengxiang Qiu Helen R Warren Eric S Torstenson Csaba P Kovesdy Yan V Sun Otis D Wilson Cassianne Robinson-Cohen Christianne L Roumie Cecilia P Chung Kelly A Birdwell Scott M Damrauer Scott L DuVall Derek Klarin Kelly Cho Yu Wang Evangelos Evangelou Claudia P Cabrera Louise V Wain Rojesh Shrestha Brian S Mautz Elvis A Akwo Muralidharan Sargurupremraj Stéphanie Debette Michael Boehnke Laura J Scott Jian'an Luan Jing-Hua Zhao Sara M Willems Sébastien Thériault Nabi Shah Christopher Oldmeadow Peter Almgren Ruifang Li-Gao Niek Verweij Thibaud S Boutin Massimo Mangino Ioanna Ntalla Elena Feofanova Praveen Surendran James P Cook Savita Karthikeyan Najim Lahrouchi Chunyu Liu Nuno Sepúlveda Tom G Richardson Aldi Kraja Philippe Amouyel Martin Farrall Neil R Poulter Markku Laakso Eleftheria Zeggini Peter Sever Robert A Scott Claudia Langenberg Nicholas J Wareham David Conen Colin Neil Alexander Palmer John Attia Daniel I Chasman Paul M Ridker Olle Melander Dennis Owen Mook-Kanamori Pim van der Harst Francesco Cucca David Schlessinger Caroline Hayward Tim D Spector Marjo-Riitta Jarvelin Branwen J Hennig Nicholas J Timpson Wei-Qi Wei Joshua C Smith Yaomin Xu Michael E Matheny Edward E Siew Cecilia Lindgren Karl-Heinz Herzig George Dedoussis Joshua C Denny Bruce M Psaty Joanna M M Howson Patricia B Munroe Christopher Newton-Cheh Mark J Caulfield Paul Elliott J Michael Gaziano John Concato Peter W F Wilson Philip S Tsao Digna R Velez Edwards Katalin Susztak Christopher J O'Donnell Adriana M Hung Todd L Edwards

Nat Genet 2019 01 21;51(1):51-62. Epub 2018 Dec 21.

Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.

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http://www.nature.com/articles/s41588-018-0303-9
Publisher Site
http://dx.doi.org/10.1038/s41588-018-0303-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365102PMC
January 2019

Inherited dilated cardiomyopathy in a large Moroccan family caused by LMNA mutation.

Anatol J Cardiol 2018 Jul;20(1):65-68

Research Center in Genomics of Human Pathologies (GENOPATH), Faculty of Medicine and Pharmacy, Mohammed V University in Rabat; Rabat-Morocco.

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http://www.anakarder.com/jvi.aspx?pdir=anatoljcardiol&pl
Publisher Site
http://dx.doi.org/10.14744/AnatolJCardiol.2018.69639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237802PMC
July 2018

Yield and Pitfalls of Ajmaline Testing in the Evaluation of Unexplained Cardiac Arrest and Sudden Unexplained Death: Single-Center Experience With 482 Families.

JACC Clin Electrophysiol 2017 12 28;3(12):1400-1408. Epub 2017 Jun 28.

Heart Center, Department of Clinical and Experimental Cardiology, Academic Medical Center, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jacep.2017.04.005DOI Listing
December 2017

Risk of arrhythmic events in drug-induced Brugada syndrome.

Heart Rhythm 2017 10 27;14(10):1434-1435. Epub 2017 Jun 27.

Heart Centre, Department of Clinical and Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Cardiovascular Genetics Center, Montreal Heart Institute, Montreal, Quebec, Canada; Department of Medicine, Université de Montréal, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2017.06.033DOI Listing
October 2017

Exome sequencing identifies primary carnitine deficiency in a family with cardiomyopathy and sudden death.

Eur J Hum Genet 2017 06 15;25(6):783-787. Epub 2017 Mar 15.

Department of Clinical and Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2017.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477358PMC
June 2017

Next-Generation Sequencing in Post-mortem Genetic Testing of Young Sudden Cardiac Death Cases.

Front Cardiovasc Med 2016 30;3:13. Epub 2016 May 30.

Department of Clinical and Experimental Cardiology, Heart Center, AMC , Amsterdam , Netherlands.

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http://dx.doi.org/10.3389/fcvm.2016.00013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885007PMC
June 2016

Prognostic significance of fever-induced Brugada syndrome.

Heart Rhythm 2016 07 23;13(7):1515-20. Epub 2016 Mar 23.

Heart Centre, Department of Clinical and Experimental Cardiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2016.03.044DOI Listing
July 2016

Genetics of sudden cardiac death.

Circ Res 2015 Jun;116(12):1919-36

From the Department of Experimental Cardiology, Academic Medical Center, Amsterdam, The Netherlands (C.R.B., N.L.); Molecular Cardiology, Fondazione Salvatore Maugeri, Pavia, Italy (S.G.P.); and Department of Molecular Medicine, University of Pavia, Pavia Italy (S.G.P.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304030DOI Listing
June 2015

A child with a white pupil.

JAMA 2014 May;311(17):1799-800

Department of Ophthalmology, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1001/jama.2013.286248DOI Listing
May 2014

Ruptured aneurysm of the right coronary sinus of Valsalva in a child with Down syndrome.

Cardiol Young 2014 Apr 18;24(2):376-8. Epub 2013 Apr 18.

1 Department of Pediatric Cardiology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1017/S1047951113000450DOI Listing
April 2014

[A boy with leukocoria].

Ned Tijdschr Geneeskd 2013 ;157(3):A5003

VUmc, afd. Oogheelkunde, Amsterdam, the Netherlands.

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March 2013