Najib Ayas

Najib Ayas

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Intermittent hypoxia impairs uterine artery function in pregnant mice.

J Physiol 2019 May 19;597(10):2639-2650. Epub 2019 Apr 19.

Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.

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https://onlinelibrary.wiley.com/doi/abs/10.1113/JP277775
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http://dx.doi.org/10.1113/JP277775DOI Listing
May 2019

Sleep Study and Oximetry Parameters for Predicting Postoperative Complications in Patients With OSA.

Chest 2019 Apr 22;155(4):855-867. Epub 2018 Oct 22.

Department of Anesthesiology, Toronto Western Hospital, University Health Network, Toronto, ON, Canada; Department of Anesthesiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2018.09.030DOI Listing
April 2019

Moral distress is associated with general workplace distress in intensive care unit personnel.

J Crit Care 2019 Apr 29;50:122-125. Epub 2018 Nov 29.

Center for Health Evaluation and Outcome Sciences, St. Paul's Hospital, University of British Columbia, 1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada; School of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, BC V6T 1Z3, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08839441183140
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http://dx.doi.org/10.1016/j.jcrc.2018.11.030DOI Listing
April 2019

Circulating biomarkers to identify cardiometabolic complications in patients with Obstructive Sleep Apnea: A systematic review.

Sleep Med Rev 2019 04 27;44:48-57. Epub 2018 Dec 27.

Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.smrv.2018.12.004DOI Listing
April 2019

Alpha Lipoic Acid Improves Endothelial Function and Oxidative Stress in Mice Exposed to Chronic Intermittent Hypoxia.

Oxid Med Cell Longev 2019 9;2019:4093018. Epub 2019 Apr 9.

Department of Anesthesiology, Pharmacology and Therapeutics, The University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1155/2019/4093018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481039PMC
April 2019

Could Adjunctive Pharmacology Mitigate Cardiovascular Consequences of OSA?

Am J Respir Crit Care Med 2019 Mar 15. Epub 2019 Mar 15.

University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1164/rccm.201811-2097PPDOI Listing
March 2019

The antioxidant alpha lipoic acid attenuates intermittent hypoxia-related renal injury in a mouse model of sleep apnea.

Sleep 2019 Mar 18. Epub 2019 Mar 18.

Departments of Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1093/sleep/zsz066DOI Listing
March 2019

Matrix metalloproteinases as possible biomarkers of obstructive sleep apnea severity - A systematic review.

Sleep Med Rev 2019 Mar 30;46:9-16. Epub 2019 Mar 30.

Division of Respiratory, Critical Care and Sleep Medicine, University of Saskatchewan, Saskatoon, Canada; Canadian Sleep and Circadian Network; Division of Angiology, Wroclaw Medical University, Wroclaw, Poland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10870792193002
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http://dx.doi.org/10.1016/j.smrv.2019.03.010DOI Listing
March 2019

Adhesion molecule gene variants and plasma protein levels in patients with suspected obstructive sleep apnea.

PLoS One 2019 17;14(1):e0210732. Epub 2019 Jan 17.

UBC Hospital Sleep Disorders Program, Division of Respiratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210732PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336279PMC
January 2019

Biomarkers of dementia in obstructive sleep apnea.

Sleep Med Rev 2018 12 13;42:139-148. Epub 2018 Aug 13.

Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montreal, Canada; Department of Psychology, Université de Montréal, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.smrv.2018.08.001DOI Listing
December 2018

Intermittent hypoxia causes histological kidney damage and increases growth factor expression in a mouse model of obstructive sleep apnea.

PLoS One 2018 1;13(2):e0192084. Epub 2018 Feb 1.

Departments of Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192084PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794148PMC
March 2018

Diagnosis and treatment of obstructive sleep apnea in adults.

CMAJ 2017 Dec;189(48):E1481-E1488

Department of Medicine (Laratta, Ayas); Sleep Disorders Program (Laratta, Ayas), University of British Columbia, Vancouver, BC; Department of Medicine (Povitz); Department of Epidemiology and Biostatistics (Povitz), Schulich School of Medicine and Dentistry, Western University, London, Ont.; Department of Medicine (Pendharkar); Department of Community Health Sciences (Pendharkar), Cumming School of Medicine, University of Calgary, Calgary, Alta.

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http://www.cmaj.ca/lookup/doi/10.1503/cmaj.170296
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http://dx.doi.org/10.1503/cmaj.170296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714700PMC
December 2017

Testing and treatment for obstructive sleep apnea in Canada: funding models must change.

CMAJ 2017 12;189(49):E1524-E1528

Departments of Medicine and Community Health Sciences (Pendharkar), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Departments of Medicine (Povitz, George) and Epidemiology, and Biostatistics (Povitz), Schulich School of Medicine & Dentistry, Western University London, Ont.; School of Population and Public Health (Bansback), Faculty of Medicine, University of British Columbia, Vancouver, BC; Department of Medicine (Morrison), Dalhousie University, Halifax, NS; Sleep Disorders Program and Department of Medicine (Ayas), University of British Columbia, Vancouver, BC.

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http://www.cmaj.ca/lookup/doi/10.1503/cmaj.170393
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http://dx.doi.org/10.1503/cmaj.170393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718892PMC
December 2017

Abstracts and Workshops 7th National Spinal Cord Injury Conference November 9 - 11, 2017 Fallsview Casino Resort Niagara Falls, Ontario, Canada.

Authors:
Mir Hatef Shojaei Mohammad Alavinia B Catharine Craven Christiana L Cheng Tova Plashkes Tian Shen Nader Fallah Suzanne Humphreys Colleen O'Connell Angelo Gary Linassi Chester Ho Christine Short Karen Ethans Rebecca Charbonneau Jerome Paquet Vanessa K Noonan Julio C Furlan Michael G Fehlings B Catharine Craven Jirapat Likitlersuang Elizabeth Sumitro Sukhvinder Kalsi-Ryan José Zariffa Dalton Wolfe Stephanie Cornell Julie Gagliardi Stephanie Marrocco Carly S Rivers Nader Nader Fallah Vanessa K Noonan David Whitehurst Carolyn Schwartz Joel Finkelstein B Catharine Craven Karen Ethans Colleen O'Connell Catherine Truchon Chester Ho A Gary Linassi Christine Short Eve Tsai Brian Drew Henry Ahn Marcel F Dvorak Jérôme Paquet Michael G Fehlings Luc Noreau Katie Lenz K Alysse Bailey David Allison David Ditor Justine Baron Jennifer Tomasone Dorothyann Curran Toba Miller Jeremy Grimshaw Bastien Moineau Milad Alizadeh-Meghrazi Gabriel Stefan Kei Masani Milos R Popovic Elizabeth Sumitro Jirapat Likitlersuang Sukhvinder Kalsi-Ryan José Zariffa Martha G Garcia-Garcia Cesar Marquez-Chin Milos R Popovic Julio C Furlan Sivakumar Gulasingam B Catharine Craven Julio C Furlan Sivakumar Gulasingam B Catharine Craven Alia Khan Clara Pujol Mark Laylor Nikola Unic Maureen Pakosh Kristin Musselman Louise M Brisbois B Catharine Craven Mary C Verrier Maryleen K Jones Roberta O'Shea Sakina Valika Kaila Holtz Elena Szefer Vanessa Noonan Brian Kwon Patricia Mills Cynthia Morin Anne Harris Christiana Cheng Arlene Aspinall Tova Plashkes Vanessa K Noonan Katherine Chan Mary C Verrier B Catharine Craven Chris Alappat Heather M Flett Julio C Furlan Kristin E Musselman James Milligan Loretta M Hillier Craig Bauman Lindsay Donaldson Joseph Lee James Milligan Joseph Lee Loretta M Hillier Karen Slonim Dalton Wolfe Lindsay Sleeth Samantha Jeske Anna Kras-Dupuis Stephanie Marrocco Samantha McRae Heather Flett Jennifer Mokry Joanne Zee Mark Bayley Jean-Francois Lemay Audrey Roy H Dany Gagnon Maryleen K Jones Roberta O'Shea Renee Theiss Heather Flett Kristina Guy Gillian Johnston Melanie Kokotow Sandra Mills Jennifer Mokry Patricia Bain Carol Scovil Pamela Houghton Deena Lala Lyndsay Orr Paul Holyoke Dalton Wolfe Lyndsay Orr Jillian Brooke Paul Holyoke Deena Lala Pamela Houghton Kathleen A Martin Ginis Robert B Shaw Matthew J Stork Christopher B McBride Julio C Furlan B Catharine Craven Lora Giangregorio Sander Hitzig Naaz Kapadia Milos R Popovic Vera Zivanovic Taufik Valiante Milos R Popovic Eleni Patsakos Louise Brisbois Farnoosh Farahani Anita Kaiser B Catharine Craven Eleni Patsakos Anita Kaiser Louise Brisbois Farnoosh Farahani B Catharine Craven Ben Mortenson Megan MacGillivray Sadeghi Mahsa Jared Adams Bonita Sawatzky Patricia Mills Kelly Arbour-Nicitopoulos Rebecca Bassett-Gunter Jennifer Leo Ritu Sharma Amy Latimer-Cheung Timothy Olds Kathleen Martin Ginis Marnie Graco Susan Cross Chinnaya Thiyagarajan Shirin Shafazand Najib Ayas Rachel Schembri Lauren Booker Carmel Nicholls Patricia Burns Mark Nash Sally Green David J Berlowitz Samantha Taran Meredith Rocchi Kathleen A Martin Ginis Shane N Sweet Jeffrey G Caron Shane N Sweet Meredith A Rocchi Walter Zelaya Shane N Sweet Austin J Bergquist Mikael F Del Castillo-Valenzuela Milos R Popovic Kei Masani Karen Ethans Alan Casey Micheal Namaka Dimitri Krassiokov-Enns Cesar Marquez-Chin Aaron Marquis Naaz Desai Vera Zivanovic Debbie Hebert Milos R Popovic Julio C Furlan B Catharine Craven Jonathan McLeod Audrey Hicks Cindy Gauthier Jasmine Arel Rachel Brosseau Audrey L Hicks Dany H Gagnon Nasrin Nejatbakhsh Anita Kaiser Sander L Hitzig Shauna Cappe Colleen McGillivray Hardeep Singh Jaya Sam Heather Flett B Catharine Craven Mary Verrier Kristin Musselman Ryan G L Koh Purbasha Garai José Zariffa Janelle Unger Alison R Oates Tarun Arora Kristin Musselman Bondi Moshe Burns Anthony Sivakumar Gulasingam B Catharine Craven Emilie Michalovic Heather L Gainforth Justine Baron Ian D Graham Shane N Sweet Brian Chan B Catharine Craven Walter Wodchis Suzanne Cadarette Murray Krahn Nicole Mittmann Keryn Chemtob Meredith A Rocchi Kelly Arbour-Nicitopoulos Dahlia Kairy Shane N Sweet Parisa Sabetian Ryan G L Koh José Zariffa Paul Yoo Stephanie N Iwasa Robart Babona-Pilipos Patrick Schneider Prashanth Velayudhan Umalkhair Ahmed Milos R Popovic Cindi M Morshead Jaeeun Yoo Masahiro Shinya Matija Milosevic Kei Masani Sharon Gabison Sunita Mathur Ethne Nussbaum Milos Popovic Mary C Verrier Kristin Musselman Jean-François Lemay Shane McCullum Kristina Guy Kristen Walden Jose Zariffa Sukhvinder Kalsi-Ryan Milad Alizadeh-Meghrazi Joseph Lee James Milligan Matt Smith Peter Athanasopoulos Tara Jeji Jennifer Howcroft Jeremy Howcroft Andrea Townson Rhonda Willms Tova Plashkes Sandra Mills Heather Flett Carol Scovil Filomena Mazzella Helen Morris Anellina Ventre Eldon Loh Stacey Guy John Kramer Tara Jeji Nancy Xia Swati Mehta Kathleen A Martin Ginis Christopher B McBride Robert B Shaw Christopher West Karen Ethans Colleen O'Connell Susan Charlifue Dany H Gagnon Manuel Jose Escalona Castillo Martin Vermette Lívia Pinheiro Carvalho Antony Karelis Dahlia Kairy Mylène Aubertin-Leheudre Cyril Duclos Pamela E Houghton Lyndsay Orr Paul Holyoke Anna Kras-Dupuis Dalton Wolfe Barry Munro Michelle Sweeny B Catharine Craven Heather Flett Sander Hitzig Farnoosh Farahani S Mohammad Alavinia Maryam Omidvar Mark Bayley Shane N Sweet Julie Gassaway Rob Shaw Minna Hong Sarah Everhart-Skeels Bethlyn Houlihan Anthony Burns Gerald Bilsky Indira Lanig Marnie Graco Susan Cross Chinnaya Thiyagarajan Shirin Shafazand Najib Ayas Rachel Schembri Lauren Booker Carmel Nicholls Patricia Burns Mark Nash Sally Green David Berlowitz Julio C Furlan Sukhvinder Kalsi-Ryan

J Spinal Cord Med 2017 11;40(6):813-869

ga Clinical Scientist, Lyndhurst Centre, Toronto Rehabilitation Institute , University Health Network; and Assistant Professor, Department of Physical Therapy, University of Toronto.

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http://dx.doi.org/10.1080/10790268.2017.1369666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778945PMC
November 2017

Uncoupling of Vascular Nitric Oxide Synthase Caused by Intermittent Hypoxia.

Oxid Med Cell Longev 2016 20;2016:2354870. Epub 2016 Oct 20.

Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1155/2016/2354870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093285PMC
July 2017

Update in Sleep-disordered Breathing 2016.

Am J Respir Crit Care Med 2017 Jun;195(12):1561-1566

7 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1164/rccm.201701-0048UPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955019PMC
June 2017

AJRCCM: 100-Year Anniversary. Sleep-Disordered Breathing: Still the New Kid on the Block.

Am J Respir Crit Care Med 2017 May;195(9):1107-1111

3 Department of Medicine University of Pennsylvania Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1164/rccm.201701-0199EDDOI Listing
May 2017

Comparative efficacy of CPAP, MADs, exercise-training, and dietary weight loss for sleep apnea: a network meta-analysis.

Sleep Med 2017 02 28;30:7-14. Epub 2016 Jun 28.

Division of Pulmonary, Allergy, Critical care & Sleep Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.sleep.2016.06.001DOI Listing
February 2017

Outcomes of Critically Ill Patients Who Have Serotype 5 Invasive Pneumococcal Disease.

J Intensive Care Med 2017 Jan 1:885066617728895. Epub 2017 Jan 1.

3 Center for Health Evaluation and Outcome Sciences, St Paul's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1177/0885066617728895DOI Listing
January 2017

The Interaction of Obesity and Nocturnal Hypoxemia on Cardiovascular Consequences in Adults with Suspected Obstructive Sleep Apnea. A Historical Observational Study.

Ann Am Thorac Soc 2016 12;13(12):2234-2241

6 Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1513/AnnalsATS.201604-263OCDOI Listing
December 2016

Cardiovascular consequences of obstructive sleep apnea.

Curr Opin Cardiol 2016 11;31(6):599-605

aDepartment of Medicine bMember of the Canadian Sleep and Circadian Network cDivision of Cardiology, St Paul's Hospital dDepartment of Pharmacology and Therapeutic, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/HCO.0000000000000329DOI Listing
November 2016

Cognitive and Other Strategies to Mitigate the Effects of Fatigue. Lessons from Staff Physicians Working in Intensive Care Units.

Ann Am Thorac Soc 2016 09;13(9):1600-6

1 Centre for Health Evaluation & Outcome Sciences, Providence Health Care, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1513/AnnalsATS.201512-817OCDOI Listing
September 2016

Cardiovascular Events in Obstructive Sleep Apnea - Can CPAP Therapy SAVE Lives?

N Engl J Med 2016 Sep 28;375(10):994-6. Epub 2016 Aug 28.

From the Sleep Disorders Center, Section of Pulmonary and Critical Care, Department of Medicine, University of Chicago, Chicago (B.M.); and the Sleep Disorders Program, Respiratory and Critical Care Divisions, Department of Medicine, University of British Columbia, Vancouver, Canada. (N.T.A.).

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http://dx.doi.org/10.1056/NEJMe1609704DOI Listing
September 2016

Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?

JAMA 2016 Sep;316(12):1298-309

Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health, Vancouver, Canada5Division of Critical Care Medicine, Department of Medicine, University of British Columbia, Vancouver, Canada7Centre Health Evaluation and Outcome Sciences, Department of Medicine, Providence Healthcare, Vancouver, Canada8Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, Canada9Division of Critical Care Medicine, Department of Medicine, St. Paul's Hospital, Vancouver, Canada.

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http://dx.doi.org/10.1001/jama.2016.12310DOI Listing
September 2016

Sleep Stage Coordination of Respiration and Swallowing: A Preliminary Study.

Dysphagia 2016 08 23;31(4):579-86. Epub 2016 Jun 23.

Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.

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http://dx.doi.org/10.1007/s00455-016-9719-5DOI Listing
August 2016

Society of Anesthesia and Sleep Medicine Guidelines on Preoperative Screening and Assessment of Adult Patients With Obstructive Sleep Apnea.

Anesth Analg 2016 08;123(2):452-73

From the *Department of Anesthesiology, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada; †Department of Anesthesiology, Weill Cornell Medical College and Hospital for Special Surgery, New York, New York; ‡Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan; §Department of Anesthesiology and Perioperative Medicine, University Hospital, St. Joseph's Hospital and Victoria Hospital, London Health Sciences Centre and St. Joseph's Health care, Western University, London, Ontario, Canada; ‖Paracelsus Medical University, Department of Anesthesiology, Perioperative Medicine and Intensive Care, Salzburg, Austria; ¶Department of Anesthesiology, Hospital for Special Surgery, Weill Cornell Medical College New York, New York; #Department of Anesthesia, Perioperative Medicine and Intensive Care, Paracelsus Medical University, Salzburg, Austria; **Department of Medicine, University of California San Diego, San Diego, California; ††Sparrow Hospital, Lansing, Michigan; ‡‡Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Texas; §§Department of Medicine, Division of Respiratory Medicine, The University of British Columbia, Vancouver, BC, Canada; ‖‖University of British Columbia, Vancouver, BC, Canada; ¶¶Department of Medicine, Emory University, Atlanta, Georgia; ##Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University Medical Center, Palo Alto, California; ***Department of Anesthesia, Critical Care and Pain Medicine, Harvard University, Cambridge, Massachusetts; †††Library and Information Services, University Health Network, University of Toronto, Toronto, Ontario, Canada; ‡‡‡Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota; §§§Department of Pulmonary, Critical Care and Sleep Medicine, Mayo Clinic, Rochester, Minnesota; ‖‖‖School of Medicine, Universidad Peruana de Ciencias Apl

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http://dx.doi.org/10.1213/ANE.0000000000001416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956681PMC
August 2016

Obstructive sleep apnoea and frequency of occupational injury.

Thorax 2016 07 15;71(7):664-6. Epub 2016 Mar 15.

Department of Medicine, University British Columbia, Vancouver, British Columbia, Canada Sleep Disorders Program, University British Columbia Hospital, Vancouver, British Columbia, Canada Centre Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, and Centre Health Evaluation Outcome Sciences, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1136/thoraxjnl-2015-207994DOI Listing
July 2016

Corrigendum to "length of stay and mortality due to clostridium difficile infection acquired in the intensive care unit" journal of Critical Care (2013) 28, 335-340.

J Crit Care 2016 Jun 16;33:266. Epub 2016 Mar 16.

Center for Health Evaluation and Outcome Sciences, Vancouver, BC, Canada; Providence Health Care and University of British Columbia, Vancouver, BC, Canada; School of Population and Public Health, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.jcrc.2016.03.001DOI Listing
June 2016

Implementation of a quality improvement initiative to reduce daily chest radiographs in the intensive care unit.

BMJ Qual Saf 2016 May 8;25(5):379-85. Epub 2015 Sep 8.

Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada Center for Health Evaluation and Outcome Sciences, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1136/bmjqs-2015-004151DOI Listing
May 2016

Development of a patient decision aid prototype for adults with obstructive sleep apnea.

Sleep Breath 2016 May 8;20(2):653-61. Epub 2015 Oct 8.

School of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, BC, V6T 1Z3, Canada.

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http://dx.doi.org/10.1007/s11325-015-1269-9DOI Listing
May 2016

One-Year Outcomes in Caregivers of Critically Ill Patients.

N Engl J Med 2016 May;374(19):1831-41

From the Department of Occupational Science and Occupational Therapy (J.I.C., L.C.), Rehabilitation Sciences Institute (J.I.C., S.Mathur, P.R.), Toronto Rehabilitation Institute, University Health Network (J.I.C., J.F., M.B.), Department of Medicine, Toronto General Research Institute, Institute of Medical Science, University Health Network (L.M.C., A.M., G.T., C.T., N.D.F., J.F., M.B., V.L., M.P., D.M., L.F., E.F., M.E.W., P.R., S.B., M.C., L.S., C.C., C.-W.C., S.K., M.S.H.), Interdepartmental Division of Critical Care (J.O.F., S. Mehta, N.D.F., N.K.J.A., J.B., C.S., M.P., C.M.L., R.F., D.C.S., T.S., B.H.C., C.C., C.-W.C., L.B., A.S.S., M.S.H.), Departments of Medicine and Critical Care (J.O.F., J.B., C.S., L.R., L.B., J.C.M.) and Keenan Research Center at the Li Ka Shing Knowledge Institute (L.B., A.S.S., J.C.M.), St. Michael's Hospital, Department of Medicine and Anesthesia, Mount Sinai Hospital (S. Mehta, C.M.L., L.R., L.S.), Department of Critical Care Medicine, Sunnybrook Health Sciences Centre (N.K.J.A., R.F., D.C.S., T.S., B.H.C., L.R.), Interdepartmental Division of Physiatry (J.F., M.B.), Department of Psychiatry, University Health Network (S.E.A., A.T.), and Department of Physical Therapy (S. Mathur), University of Toronto, Toronto, the Departments of General Internal Medicine and Critical Care, St. Joseph's Healthcare (J.C.R.), and the Departments of Pediatrics (K.C.) and Medicine (D.C.), Division of Critical Care and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (F.L., P.H.) and the School of Rehabilitation and Research Centre on Aging, Health and Social Services Centre (M.L.), University of Sherbrooke, Sherbrooke, QC, the Department of Critical Care, University of Ottawa, Ottawa (H.M.), the Department of Medicine Division of Critical Care, Maisonneuve Rosemont Hospital, University of Montreal, Montreal (Y.S.), and the Department of Medicine, St. Paul's H

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http://dx.doi.org/10.1056/NEJMoa1511160DOI Listing
May 2016

Multipronged strategy to reduce routine-priority blood testing in intensive care unit patients.

J Crit Care 2016 Feb 25;31(1):212-6. Epub 2015 Sep 25.

Department of Medicine, University of British Columbia, Vancouver, BC, Canada; Center for Health Evaluation and Outcome Sciences, St Paul's Hospital and University of British Columbia, Vancouver, BC, Canada V6Z1Y6; Division of Critical Care Medicine, St Paul's Hospital and University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2015.09.013DOI Listing
February 2016

Moral distress in intensive care unit professionals is associated with profession, age, and years of experience.

J Crit Care 2016 Feb 20;31(1):178-82. Epub 2015 Oct 20.

Department of Psychology, University of British Columbia, Vancouver, B.C., Canada.

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http://dx.doi.org/10.1016/j.jcrc.2015.10.011DOI Listing
February 2016

Turning Dreams into Nightmares: Different Metabolic Effects of Obstructive Events in Rapid Eye Movement versus Non-Rapid Eye Movement Sleep.

Am J Respir Crit Care Med 2015 Nov;192(9):1034-5

4 Respiratory and Critical Care Divisions University of British Columbia Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1164/rccm.201507-1504EDDOI Listing
November 2015

Response.

Chest 2015 Nov;148(5):e166-e167

Department of Experimental Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1378/chest.15-1952DOI Listing
November 2015

Gas density alters expiratory time constants before and after experimental lung injury.

Exp Physiol 2015 Oct;100(10):1217-28

School of Kinesiology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://doi.wiley.com/10.1113/EP085205
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http://dx.doi.org/10.1113/EP085205DOI Listing
October 2015

Cerebrovascular Response to CO2 Following 10 Days of Intermittent Hypoxia in Humans.

Aerosp Med Hum Perform 2015 Sep;86(9):782-6

Faculty of Medicine and the School of Kinesiology, University of British Columbia - Vancouver, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.3357/AMHP.4192.2015DOI Listing
September 2015

Obstructive Sleep Apnea and Kidney Disease: A Potential Bidirectional Relationship?

J Clin Sleep Med 2015 Aug 15;11(8):915-24. Epub 2015 Aug 15.

Departments of Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.5664/jcsm.4946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513269PMC
August 2015

Update in Sleep Medicine 2014.

Am J Respir Crit Care Med 2015 Aug;192(4):415-20

3 Section of Pediatric Sleep Medicine, Department of Pediatrics, Pritzker School of Medicine, Biological Sciences Division, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1164/rccm.201503-0647UPDOI Listing
August 2015

Exploring the Potential Cost-Effectiveness of Patient Decision Aids for Use in Adults with Obstructive Sleep Apnea: A Case Study.

Med Decis Making 2015 07 24;35(5):671-82. Epub 2014 Oct 24.

School of Population and Public Health, University of British Columbia, Vancouver, Canada (LT,NB)

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http://dx.doi.org/10.1177/0272989X14556676DOI Listing
July 2015

Epidemiology of Sleep Disturbances and Cardiovascular Consequences.

Can J Cardiol 2015 Jul 12;31(7):873-9. Epub 2015 Mar 12.

Divisions of Critical Care and Respiratory Medicine, Department of Medicine, University of British Columbia; Sleep Disorders Program, UBC Hospital; Division of Critical Care Medicine, Providence Health Care, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2015.03.011DOI Listing
July 2015

Central sleep apnoea in congestive heart failure.

Lancet Respir Med 2015 Jul 11;3(7):507-8. Epub 2015 Jun 11.

University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/S2213-2600(15)00235-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847542PMC
July 2015

Treatment of Central Sleep Apnea with Adaptive Servoventilation in Chronic Heart Failure.

Am J Respir Crit Care Med 2015 Jul;192(2):132-3

4 Division of Pulmonary, Critical Care, and Sleep Medicine University of California, San Diego La Jolla, California.

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http://dx.doi.org/10.1164/rccm.201506-1131EDDOI Listing
July 2015

Nitric Oxide Bioavailability in Obstructive Sleep Apnea: Interplay of Asymmetric Dimethylarginine and Free Radicals.

Sleep Disord 2015 6;2015:387801. Epub 2015 May 6.

Department of Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.

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http://dx.doi.org/10.1155/2015/387801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438195PMC
June 2015

The effect of OSA on work disability and work-related injuries.

Chest 2015 May;147(5):1422-1428

Department of Experimental Medicine, University of British Columbia; Division of Respiratory Medicine, Vancouver Hospital; Sleep Disorders Program, University of British Columbia Hospital, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1378/chest.14-1949DOI Listing
May 2015

Swallowing and breathing patterns during sleep in patients with obstructive sleep apnea.

Sleep Breath 2015 Mar 24;19(1):377-84. Epub 2014 Jul 24.

Department of Oral Health Sciences, The University of British Columbia, 2199 Wesbrook Mall, V6T 1Z3, Vancouver, BC, Canada,

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http://dx.doi.org/10.1007/s11325-014-1031-8DOI Listing
March 2015

Attributable length of stay and mortality of major bleeding as a complication of therapeutic anticoagulation in the intensive care unit.

J Patient Saf 2015 Mar;11(1):23-7

From the *Division of Critical Care Medicine and Department of Medicine, Providence Health Care and University of British Columbia; †Center for Health Evaluation and Outcome Sciences, Providence Health Care; ‡Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, Vancouver, British Columbia; §Division of Critical Care Medicine, University of Toronto, Toronto, Ontario; ∥School of Population and Public Health, University of British Columbia; and ¶CIHR Canadian HIV Trials Network, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/PTS.0000000000000149DOI Listing
March 2015

The patient's or society's: whose quality of life is it anyway?

Sleep 2014 Dec 1;37(12):1885-6. Epub 2014 Dec 1.

School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada: Centre for Health Evaluation and Outcome Sciences, St Paul's Hospital, Vancouver, BC, Canada: Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Research Institute, Vancouver, BC, Canada.

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http://dx.doi.org/10.5665/sleep.4234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548511PMC
December 2014

Cardiovascular complications of sleep apnea: role of oxidative stress.

Oxid Med Cell Longev 2014 6;2014:985258. Epub 2014 Mar 6.

Department of Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.

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http://dx.doi.org/10.1155/2014/985258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964889PMC
November 2014

Impact of work schedules on sleep duration of critical care nurses.

Am J Crit Care 2014 Jul;23(4):290-5

A. J. Hirsch Allen is a doctoral student at the University of British Columbia, Vancouver, British Columbia. Julie E. Park is a statistician at the Center for Health Evaluation and Outcomes Sciences, St Paul's Hospital, Vancouver, British Columbia. Nassim Adhami is a nurse at St Paul's Hospital. Demetrios Sirounis is a critical care physician in the Division of Critical Care Medicine, Providence Health Care and University of British Columbia. Harriet Tholin is a patient services manager in the intensive care unit, Vancouver General Hospital, Vancouver, British Columbia. Peter Dodek is a professor at the Center for Health Evaluation and Outcomes Sciences, St Paul's Hospital, and a physician in the Division of Critical Care Medicine, Providence Health Care and University of British Columbia. Ann E. Rogers is a professor at the Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia. Najib Ayas Najib Ayas is a staff member at Vancouver General Hospital and Providence Health Care, and an associate professor and head of the Division of Critical Care Medicine, University of British Columbia.

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http://dx.doi.org/10.4037/ajcc2014876DOI Listing
July 2014

Chronic intermittent hypoxia causes endothelial dysfunction in a mouse model of diet-induced obesity.

Sleep Med 2014 May 19;15(5):596-602. Epub 2014 Feb 19.

Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2014.01.013DOI Listing
May 2014

Insights into obstructive sleep apnea research.

Sleep Med 2014 May 10;15(5):485-95. Epub 2014 Feb 10.

Department of Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2014.01.009DOI Listing
May 2014

Carotid intima media thickness in patients with obstructive sleep apnea: comparison with a community-based cohort.

Lung 2014 Apr 29;192(2):297-303. Epub 2014 Jan 29.

Department of Respiratory Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s00408-014-9556-yDOI Listing
April 2014

Length of stay and mortality due to Clostridium difficile infection acquired in the intensive care unit.

J Crit Care 2013 Aug 18;28(4):335-40. Epub 2013 Jan 18.

Center for Health Evaluation and Outcome Sciences, Vancouver, BC Canada.

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http://dx.doi.org/10.1016/j.jcrc.2012.11.008DOI Listing
August 2013

Patient preferences and experiences of CPAP and oral appliances for the treatment of obstructive sleep apnea: a qualitative analysis.

Sleep Breath 2013 May 26;17(2):659-66. Epub 2012 Jul 26.

Oral Health Sciences, University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, Canada, V6T 1Z3.

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http://dx.doi.org/10.1007/s11325-012-0739-6DOI Listing
May 2013

Dynamic cerebral autoregulation during and following acute hypoxia: role of carbon dioxide.

J Appl Physiol (1985) 2013 May 7;114(9):1183-90. Epub 2013 Mar 7.

Faculty of Medicine, University of British Columbia-Vancouver, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1152/japplphysiol.00024.2013DOI Listing
May 2013

Video-laryngoscopy versus direct laryngoscopy in critically ill patients: a pilot randomized trial.

Can J Anaesth 2012 Nov 30;59(11):1032-9. Epub 2012 Aug 30.

Division of Critical Care Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s12630-012-9775-8DOI Listing
November 2012

Effects of 10 days of modest intermittent hypoxia on circulating measures of inflammation in healthy humans.

Sleep Breath 2012 Sep 9;16(3):657-62. Epub 2011 Jul 9.

School of Human Kinetics, Osborne Centre, Unit II, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s11325-011-0555-4DOI Listing
September 2012

The relationship between organizational culture and family satisfaction in critical care.

Crit Care Med 2012 May;40(5):1506-12

Center for Health Evaluation and Outcome Sciences and Division of Critical Care Medicine, Providence Health Care and University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/CCM.0b013e318241e368DOI Listing
May 2012

Cardiovascular consequences of sleep apnea.

Lung 2012 Apr 3;190(2):113-32. Epub 2011 Nov 3.

Department of Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.

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http://dx.doi.org/10.1007/s00408-011-9340-1DOI Listing
April 2012

Restricting resident work hours: the good, the bad, and the ugly.

Crit Care Med 2012 Mar;40(3):960-6

Division of Critical Care Medicine, Department of Medicine, University of British Columbia, Vancouver, BC.

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http://dx.doi.org/10.1097/CCM.0b013e3182413bc5DOI Listing
March 2012

Organizational and safety culture in Canadian intensive care units: relationship to size of intensive care unit and physician management model.

J Crit Care 2012 Feb 29;27(1):11-7. Epub 2011 Sep 29.

Center for Health Evaluation and Outcome Sciences and Division of Critical Care Medicine, Providence Health Care and University of British Columbia, Vancouver, British Columbia, Canada V6Z 1Y6.

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http://dx.doi.org/10.1016/j.jcrc.2011.07.078DOI Listing
February 2012

The demise of portable monitoring to diagnose OSA? Not so fast!

Sleep 2011 Jun 1;34(6):691-2. Epub 2011 Jun 1.

Respiratory and Critical Care Divisions, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.5665/SLEEP.1026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099490PMC
June 2011

Qualitative analysis of an intensive care unit family satisfaction survey.

Crit Care Med 2011 May;39(5):1000-5

Center for Health Evaluation and Outcome Sciences, St Paul's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/CCM.0b013e31820a92fbDOI Listing
May 2011

The relationship between mouth opening and sleep stage-related sleep disordered breathing.

J Clin Sleep Med 2011 Apr;7(2):181-6

Department of Oral Health Sciences, University of British Columbia, Vancouver, BC, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077347PMC
April 2011

Intensive nursing work schedules and the risk of hypoglycaemia in critically ill patients who are receiving intravenous insulin.

Qual Saf Health Care 2010 Dec 4;19(6):e42. Epub 2010 Aug 4.

Providence Health Care, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1136/qshc.2009.036020DOI Listing
December 2010

Medical simulation in respiratory and critical care medicine.

Lung 2010 Dec 24;188(6):445-57. Epub 2010 Sep 24.

Faculty of Medicine, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada.

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http://dx.doi.org/10.1007/s00408-010-9260-5DOI Listing
December 2010

Can telemedicine improve CPAP adherence?

Thorax 2010 Dec 26;65(12):1035-6. Epub 2010 Oct 26.

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http://dx.doi.org/10.1136/thx.2010.140897DOI Listing
December 2010

Incidence of medication errors and adverse drug events in the ICU: a systematic review.

Qual Saf Health Care 2010 Oct 29;19(5):e7. Epub 2010 Jul 29.

Department of Medicine, Providence Health Care, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1136/qshc.2008.030783DOI Listing
October 2010

Influence of residency training on multiple attempts at endotracheal intubation.

Can J Anaesth 2010 Sep 15;57(9):823-9. Epub 2010 Jun 15.

Department of Medicine, Division of Critical Care Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s12630-010-9345-xDOI Listing
September 2010

Can we improve sleep quality by changing the way we ventilate patients?

Lung 2010 Jan-Feb;188(1):1-3. Epub 2009 Oct 21.

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http://dx.doi.org/10.1007/s00408-009-9189-8DOI Listing
April 2010

The impact of prolonged continuous wakefulness on resident clinical performance in the intensive care unit: a patient simulator study.

Crit Care Med 2010 Mar;38(3):766-70

Critical Care Division and Department of Medicine, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1097/CCM.0b013e3181cd122aDOI Listing
March 2010

Residual sleep apnea on polysomnography after 3 months of CPAP therapy: clinical implications, predictors and patterns.

Sleep Med 2010 Feb 18;11(2):119-25. Epub 2010 Jan 18.

Department of Medicine, Bon Secours Hospital, Tralee, Co. Kerry, Ireland.

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http://dx.doi.org/10.1016/j.sleep.2009.05.017DOI Listing
February 2010

If you weigh too much, maybe you should try sleeping more.

Authors:
Najib T Ayas

Sleep 2010 Feb;33(2):143-4

Department of Medicine, Critical Care Division, Sleep Disorders Program, University of British Columbia, Vancouver, BC, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817899PMC
http://dx.doi.org/10.1093/sleep/33.2.143DOI Listing
February 2010

Medication error reporting systems: a survey of canadian intensive care units.

Can J Hosp Pharm 2010 Jan;63(1):20-4

, BSc, is with the Centre for Health Evaluation and Outcome Sciences, Providence Health Care, Vancouver, British Columbia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832561PMC
January 2010

Effect of ambient workload in the intensive care unit on mortality and time to discharge alive.

Healthc Q 2009 ;12 Spec No Patient:8-14

Centre for Health Evaluation and Outcome Sciences, St. Paul's Hospital, and the Program in Critical Care Medicine, University of British Columbia, both in Vancouver, British Columbia.

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November 2009