Nagaswamy Kumaragurubaran

Nagaswamy Kumaragurubaran

UNVERIFIED PROFILE

Are you Nagaswamy Kumaragurubaran?   Register this Author

Register author
Nagaswamy Kumaragurubaran

Nagaswamy Kumaragurubaran

Publications by authors named "Nagaswamy Kumaragurubaran"

Are you Nagaswamy Kumaragurubaran?   Register this Author

13Publications

145Reads

14Profile Views

Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand.

Bioorg Med Chem Lett 2018 08 26;28(15):2605-2610. Epub 2018 Jun 26.

Department of Chemistry, Purdue University, West Lafayette, IN 47907, United States; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, United States; Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2018.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085084PMC
August 2018

Design, synthesis, and X-ray structural studies of BACE-1 inhibitors containing substituted 2-oxopiperazines as P1'-P2' ligands.

Bioorg Med Chem Lett 2017 06 8;27(11):2432-2438. Epub 2017 Apr 8.

Department of Chemistry, Purdue University, West Lafayette, IN 47907, United States; Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, United States; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2017.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479133PMC
June 2017

Memapsin 2 (beta-secretase) inhibitors: drug development.

Curr Alzheimer Res 2008 Apr;5(2):121-31

Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/156720508783954730DOI Listing
April 2008

An expedient, facile and simple one-pot synthesis of 2-methylenealkanoates and alkanenitriles from the Baylis-Hillman bromides in aqueous media.

Nat Protoc 2007 ;2(11):2665-76

School of Chemistry, University of Hyderabad, Hyderabad-500 046, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2007.369DOI Listing
February 2008

Recent developments of structure based beta-secretase inhibitors for Alzheimer's disease.

Curr Top Med Chem 2005 ;5(16):1609-22

Departments of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/156802605775009711DOI Listing
June 2006

The Baylis-Hillman reaction: one-pot facile synthesis of 2,4-functionalized 1,4-pentadienes.

J Org Chem 2002 Oct;67(20):7135-7

School of Chemistry, University of Hyderabad, Hyderabad-500 046, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo0257952DOI Listing
October 2002

Direct L-proline-catalyzed asymmetric alpha-amination of ketones.

J Am Chem Soc 2002 Jun;124(22):6254-5

Center for Catalysis, Department of Chemistry, Aarhus University, DK-8000 Aarhus C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja026412kDOI Listing
June 2002

Direct catalytic asymmetric aldol reactions of aldehydes.

Chem Commun (Camb) 2002 Mar(6):620-1

Center for Metal Catalyzed Reactions, Department of Chemistry, Aarhus University, DK-8000, Aarhus C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/b200681bDOI Listing
March 2002