Nadia Dahmane

Nadia Dahmane

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Nadia Dahmane

Nadia Dahmane

Publications by authors named "Nadia Dahmane"

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SHP2 regulates proliferation and tumorigenicity of glioma stem cells.

J Neurooncol 2017 Dec 29;135(3):487-496. Epub 2017 Aug 29.

Department of Neurosurgery, University of Pennsylvania School of Medicine, 502 Stemmler Hall, 36th and Hamilton Walk, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s11060-017-2610-xDOI Listing
December 2017

Detection of EGFRvIII in Glioblastoma via Perfusion Magnetic Resonance Imaging Signature Consistent with Deep Peritumoral Infiltration: The -Index.

Clin Cancer Res 2017 Aug 20;23(16):4724-4734. Epub 2017 Apr 20.

Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559313PMC
August 2017

Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques.

Neuro Oncol 2016 Mar 16;18(3):417-25. Epub 2015 Jul 16.

Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania (L.M., J.M.P., M.A., L.R., N.D., D.M.O.); Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania (H.A., X.D., R.L.W., M.B., C.D.); Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania (H.A., X.D., V.P., M.B., C.D.); Department of Biomedical Informatics, Northwestern University Feinberg School of Medicine, Chicago, Illinois (Y.B., S.P., R.V.D.); Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, Texas (G.B.); Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (M.M.-L., D.M.O.).

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http://dx.doi.org/10.1093/neuonc/nov127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767233PMC
March 2016

Pyrvinium attenuates Hedgehog signaling downstream of smoothened.

Cancer Res 2014 Sep 3;74(17):4811-21. Epub 2014 Jul 3.

Molecular Oncology Program, Department of Surgery, University of Miami, Miami, Florida. Sylvester Cancer Center, University of Miami, Miami, Florida. Department of Biochemistry and Molecular Biology, University of Miami, Miami, Florida.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321822PMC
September 2014

NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis.

Cancer Res 2014 Sep 18;74(17):4741-51. Epub 2014 Jul 18.

Molecular Oncology Program, Division of Surgical Oncology, Dewitt Daughtry Family Department of Surgery, and Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, Florida.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154994PMC
September 2014

Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development.

Development 2012 Jun 18;139(11):1903-9. Epub 2012 Apr 18.

The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1242/dev.075606DOI Listing
June 2012

Design, synthesis, and biological evaluation of estrone-derived hedgehog signaling inhibitors.

Tetrahedron 2011 Dec;67(52):10261-10266

Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.tet.2011.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244726PMC
December 2011

Studies directed toward the elucidation of the pharmacophore of steroid-based Sonic Hedgehog signaling inhibitors.

Org Lett 2011 Oct 9;13(19):5140-3. Epub 2011 Sep 9.

Department of Chemistry, The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://pubs.acs.org/doi/abs/10.1021/ol202020c
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http://dx.doi.org/10.1021/ol202020cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184309PMC
October 2011

Stereoselective synthesis of F-ring saturated estrone-derived inhibitors of Hedgehog signaling based on cyclopamine.

Org Lett 2011 Sep 15;13(18):4786-9. Epub 2011 Aug 15.

Department of Chemistry, The University of Pennsylvania , Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1021/ol2017966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170508PMC
September 2011

Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia.

Blood 2011 Mar 7;117(10):2901-9. Epub 2011 Jan 7.

Molecular Oncology Program, Division of Surgical Oncology, Dewitt Daughtry Family Department of Surgery and University of Miami Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1182/blood-2010-05-286351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062300PMC
March 2011

Differential modulation of Sonic-hedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network.

Dev Neurosci 2010 Mar 25;32(1):59-70. Epub 2010 Mar 25.

CNRS Institut de Biologie du Développement de Marseille (CNRS Univ. Méditerranée), Campus de Luminy, Marseille, France.

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http://dx.doi.org/10.1159/000274458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866582PMC
March 2010

ZNF238 is expressed in postmitotic brain cells and inhibits brain tumor growth.

Cancer Res 2010 Feb 26;70(3):1236-46. Epub 2010 Jan 26.

The Wistar Institute, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2249DOI Listing
February 2010

The full-length unprocessed hedgehog protein is an active signaling molecule.

J Biol Chem 2010 Jan 17;285(4):2562-8. Epub 2009 Nov 17.

Department of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.

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http://dx.doi.org/10.1074/jbc.M109.078626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807313PMC
January 2010

Design and synthesis of inhibitors of Hedgehog signaling based on the alkaloid cyclopamine.

Org Lett 2009 Jul;11(13):2824-7

Department of Chemistry, The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://pubs.acs.org/doi/abs/10.1021/ol900974u
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http://dx.doi.org/10.1021/ol900974uDOI Listing
July 2009

Neuronal distribution of spatial in the developing cerebellum and hippocampus and its somatodendritic association with the kinesin motor KIF17.

Exp Cell Res 2007 Dec 20;313(20):4107-19. Epub 2007 Sep 20.

INSERM-ERM206, laboratoire TAGC, Case 928, Parc Scientifique de Luminy, 13288 Marseille Cedex 9, France.

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http://dx.doi.org/10.1016/j.yexcr.2007.09.006DOI Listing
December 2007

Sonic hedgehog signaling in forebrain development and its interactions with pathways that modify its effects.

Trends Cell Biol 2006 Nov 9;16(11):597-605. Epub 2006 Oct 9.

IBDML, UMR 6216, Campus de Luminy, Université de la Méditerranée, 13288 Marseille cedex 09, France.

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http://linkinghub.elsevier.com/retrieve/pii/S096289240600268
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http://dx.doi.org/10.1016/j.tcb.2006.09.007DOI Listing
November 2006

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain.

Development 2005 Jan 16;132(2):335-44. Epub 2004 Dec 16.

The Skirball Institute, NYU School of Medicine, 540 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1242/dev.01567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431583PMC
January 2005

A gene expression map of human chromosome 21 orthologues in the mouse.

Nature 2002 Dec;420(6915):586-90

Skirball Institute, Developmental Genetics Program and Department of Cell Biology, New York University School of Medicine, 540 First Avenue, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/nature01270DOI Listing
December 2002

Gli and hedgehog in cancer: tumours, embryos and stem cells.

Nat Rev Cancer 2002 May;2(5):361-72

The Skirball Institute, Department of Cell Biology, New York University School of Medicine, New York 10016, USA.

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http://dx.doi.org/10.1038/nrc796DOI Listing
May 2002

Hedgehog-Gli signalling and the growth of the brain.

Nat Rev Neurosci 2002 Jan;3(1):24-33

The Skirball Institute, Developmental Genetics Program and Department of Cell Biology, New York University School of Medicine, 540 First Avenue, New York 10016, USA.

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http://dx.doi.org/10.1038/nrn704DOI Listing
January 2002