Nadarajah Sreeharan, MD PhD FRCP FACP - Institute of Pharmaceutical Sciences - Visiting Professor

Nadarajah Sreeharan

MD PhD FRCP FACP

Institute of Pharmaceutical Sciences

Visiting Professor

London | United Kingdom

Main Specialties: Cardiovascular Disease

Additional Specialties: Cardiovascular Medicine

ORCID logohttps://orcid.org/0000-0002-4839-6804


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Nadarajah Sreeharan, MD PhD FRCP FACP - Institute of Pharmaceutical Sciences - Visiting Professor

Nadarajah Sreeharan

MD PhD FRCP FACP

Introduction

Prof Sreeharan currently holds Visiting Professorships at King’s College, London & University of Jaffna, Sri Lanka and acts as a Consultant to the Biotechnology Industry. He graduated from the University of Colombo in 1970 with 1st class honours and had his initial postgraduate training at the University of Peradeniya obtaining the MD (Colombo) and subsequently completed the MRCP and a PhD in Cardiovascular physiology at the British Heart Foundation Department of Cardiovascular Studies in Leeds, UK. He is a Fellow of the Royal College of Physicians of London. Edinburgh and Glasgow and of the American College of Physicians.

He was formerly the Foundation Professor of Medicine at the University of Jaffna and held Visiting Professorships at the University of Alberta, Canada, University of Surrey, UK and the UITM Medical Faculty in Kuala Lumpur, Malaysia. During his tenure as Senior Vice President & European Medical Director in the Global R&D organisation at GlaxoSmithKline, he chaired an integrated medical department based across the European countries with oversight for the research & development of new medicines across multiple therapeutic areas. He led teams that developed the first non-ergot selective dopamine agonist for Parkinson’s Disease (ropinirole), the first beta blocker for Heart Failure (carvedilol), an insulin sensitizer for Type 2 Diabetes (rosiglitazone), a combination steroid/LABA for COPD (Seretide), an SSRI for depression/anxiety spectrum (paroxetine), a 5 alpha reductase inhibitor for BPH (dutasteride) and a topoisomerase inhibitor for Ovarian and Small cell Lung cancers (topotecan).

As an Officer of the Board of Examiners in Pharmaceutical Medicine at the Royal College of Physicians, an advisor to the National Board of Medical Examiners in the USA and a faculty to the Scholars in Clinical Science Program at the Harvard Medical School, he facilitated the international development of Pharmaceutical Medicine as an accredited medical specialty. Prof Sreeharan has authored several publications and book chapters on atrial receptors, endothelium dependent relaxation factor, drug development, clinical cardiology and tropical medicine.

Primary Affiliation: Institute of Pharmaceutical Sciences - London , United Kingdom

Specialties:

Additional Specialties:

Research Interests:


View Nadarajah Sreeharan’s Resume / CV

Education

Oct 1985
Royal College of Physicians, London, Edinburgh
FRCP
Jan 1976 - Sep 1979
University of Leeds
PhD
Cardiovascular Studies
Jan 1976 - Oct 1976
Royal College of Physicians
MRCP (UK)
Oct 1971 - Mar 1974
University of Colombo
MD
Medicine
Oct 1965 - Sep 1970
University of Colombo
MBBS
Faculty of Pharmaceutical Medicine of the Royal College of Physicians
FFPM
Royal College of Physicians
FRCP
Royal College of Physicians, London
FRCP
Americal College of Physicians
FACP

Experience

Jan 2001 - Jan 1994
GlaxoSmithKline Research and Development
Senior Vice President
Medical
Jun 1980 - May 1980
University of Jaffna
Professor of Medicine
Medicine

Publications

22Publications

108Reads

80Profile Views

183PubMed Central Citations

Development of triglyceride-lowering drugs to address residual cardiovascular risk: strategic and clinical considerations.

Eur Heart J Cardiovasc Pharmacother 2018 10;4(4):237-242

Institute of Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, James Clerk Maxwell Building, 57 Waterloo Road, London, UK.

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https://academic.oup.com/ehjcvp/article/4/4/237/5060722
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http://dx.doi.org/10.1093/ehjcvp/pvy029DOI Listing
October 2018
37 Reads

Amoebic Liver Abscess and Indigenous Alcoholic Beverages in the Tropics.

J Trop Med 2018 10;2018:6901751. Epub 2018 Jul 10.

Department of Medicine, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.

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http://dx.doi.org/10.1155/2018/6901751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077556PMC
July 2018
70 Reads

Persistent impairment of endothelium-dependent relaxation to acetylcholine and progression of atherosclerosis following 6 weeks of cholesterol feeding in the rabbit.

Can J Physiol Pharmacol 1989 Nov;67(11):1454-60

Department of Medicine, University of Alberta, Edmonton, Canada.

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November 1989
1.550 Impact Factor

Evolution of the responses to exercise in left ventricular aneurysms after anterior wall acute myocardial infarction.

Am J Cardiol 1988 Feb;61(4):236-9

Department of Medicine, University of Alberta, Edmonton, Canada.

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February 1988
3.280 Impact Factor

Endothelium-dependent relaxation and experimental atherosclerosis in the rabbit aorta.

Can J Physiol Pharmacol 1986 Nov;64(11):1451-3

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November 1986
7 Citations
1.550 Impact Factor

Randomised trial of antivenom in snake envenomation with prolonged clotting time.

Authors:
N Sreeharan

Br Med J (Clin Res Ed) 1985 Aug;291(6493):482

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1416286PMC
August 1985
1 Citation

Psychiatric illness and the general physician in a developing country.

Authors:
N Sreeharan

Trop Doct 1984 Apr;14(2):55

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http://dx.doi.org/10.1177/004947558401400203DOI Listing
April 1984
0.530 Impact Factor

Hypereosinophilic syndrome.

Ceylon Med J 1983 Jun;28(2):93-5

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June 1983

Assessment of the interaction of warfarin with aspirin and dipyridamole.

Thromb Haemost 1982 Feb;47(1):77

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February 1982
4.984 Impact Factor

Humoral nature of the urine response to simulation of atrial receptors.

Q J Exp Physiol 1981 Oct;66(4):431-8

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October 1981
2 Citations

The role of renal nerves in the diuresis and natriuresis caused by stimulation of atrial receptors.

Q J Exp Physiol 1981 Apr;66(2):163-78

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April 1981
3 Citations

Effect of exercise in hypertension controlled with metoprolol or methyldopa.

Clin Sci (Lond) 1979 Dec;57 Suppl 5:391s-392s

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December 1979
5.600 Impact Factor

Does the renal humoral response to stimulation of atrial receptors include a natriuresis? [proceedings].

J Physiol 1979 Jun;291:43P-44P

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June 1979
1 Citation
5.040 Impact Factor

The temperature in the vagal core during graded cooling in the dog [proceedings].

J Physiol 1979 May;290(2):11P-12P

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May 1979
5.040 Impact Factor

The role of renal nerves in the diuresis and natriuresis caused by stimulation of atrial receptors [proceedings].

J Physiol 1979 Feb;287:17P-18-P

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February 1979
5.040 Impact Factor

Top co-authors

L Hsu
L Hsu

University of California

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