Nacksung Kim

Nacksung Kim

UNVERIFIED PROFILE

Are you Nacksung Kim?   Register this Author

Register author
Nacksung Kim

Nacksung Kim

Publications by authors named "Nacksung Kim"

Are you Nacksung Kim?   Register this Author

84Publications

1387Reads

40Profile Views

Rev-erbα Negatively Regulates Osteoclast and Osteoblast Differentiation through p38 MAPK Signaling Pathway.

Mol Cells 2020 Jan;43(1):34-47

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14348/molcells.2019.0232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999712PMC
January 2020

MYO1D binds with kinase domain of the EGFR family to anchor them to plasma membrane before their activation and contributes carcinogenesis.

Oncogene 2019 12 16;38(49):7416-7432. Epub 2019 Aug 16.

Departments of Pharmacology, Chonnam National University Medical School, Gwangju, 61469, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-019-0954-8DOI Listing
December 2019

Adaptor protein CrkII negatively regulates osteoblast differentiation and function through JNK phosphorylation.

Exp Mol Med 2019 Sep 25;51(9):111. Epub 2019 Sep 25.

Department of Pharmacology, Chonnam National University Medical School, Gwangju, 61469, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s12276-019-0314-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802640PMC
September 2019

The IRF2BP2-KLF2 axis regulates osteoclast and osteoblast differentiation.

BMB Rep 2019 Jul;52(7):469-474

Departments of Pharmacology and Biomedical Sciences, Chonnam National University Medical School, Gwangju 61469, Korea.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675247PMC
July 2019

Role of anoctamin 5, a gene associated with gnathodiaphyseal dysplasia, in osteoblast and osteoclast differentiation.

Bone 2019 03 14;120:432-438. Epub 2018 Dec 14.

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Republic of Korea; Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju 61469, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2018.12.010DOI Listing
March 2019

TRIM38 regulates NF-κB activation through TAB2 degradation in osteoclast and osteoblast differentiation.

Bone 2018 08 16;113:17-28. Epub 2018 May 16.

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Republic of Korea; Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju 61469, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2018.05.009DOI Listing
August 2018

c-Src-Dependent and -Independent Functions of Matk in Osteoclasts and Osteoblasts.

J Immunol 2018 04 12;200(7):2455-2463. Epub 2018 Feb 12.

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Republic of Korea; and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1700582DOI Listing
April 2018

Endoplasmic Reticulum-Bound Transcription Factor CREBH Stimulates RANKL-Induced Osteoclastogenesis.

J Immunol 2018 03 29;200(5):1661-1670. Epub 2018 Jan 29.

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Republic of Korea;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1701036DOI Listing
March 2018

BCAP promotes osteoclast differentiation through regulation of the p38-dependent CREB signaling pathway.

Bone 2018 02 6;107:188-195. Epub 2017 Dec 6.

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Republic of Korea; Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju 61469, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2017.12.005DOI Listing
February 2018

Tusc2/Fus1 regulates osteoclast differentiation through NF-κB and NFATc1.

BMB Rep 2017 Sep;50(9):454-459

Departments of Pharmacology and Biomedical Sciences, Chonnam National University Medical School, Gwangju 61469, Korea.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625692PMC
http://dx.doi.org/10.5483/bmbrep.2017.50.9.026DOI Listing
September 2017

Functional validation of novel MKS3/TMEM67 mutations in COACH syndrome.

Sci Rep 2017 08 31;7(1):10222. Epub 2017 Aug 31.

Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-10652-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579020PMC
August 2017

ATF3 modulates calcium signaling in osteoclast differentiation and activity by associating with c-Fos and NFATc1 proteins.

Bone 2017 02 6;95:33-40. Epub 2016 Nov 6.

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Republic of Korea; Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju 61469, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2016.11.005DOI Listing
February 2017

RCANs regulate the convergent roles of NFATc1 in bone homeostasis.

Sci Rep 2016 12 5;6:38526. Epub 2016 Dec 5.

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep38526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137032PMC
December 2016

STAT5 is a key transcription factor for IL-3-mediated inhibition of RANKL-induced osteoclastogenesis.

Sci Rep 2016 08 3;6:30977. Epub 2016 Aug 3.

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep30977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971530PMC
August 2016

GATA4 negatively regulates bone sialoprotein expression in osteoblasts.

BMB Rep 2016 Jun;49(6):343-8

Departments of Pharmacology and Biomedical Sciences, Chonnam National University Medical School, Gwangju 61469, Korea.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070723PMC
http://dx.doi.org/10.5483/bmbrep.2016.49.6.032DOI Listing
June 2016

Downregulation of Runx2 by 1,25-Dihydroxyvitamin D₃ Induces the Transdifferentiation of Osteoblasts to Adipocytes.

Int J Mol Sci 2016 May 19;17(5). Epub 2016 May 19.

Department of Pharmacology, Chonnam National University Medical School, Gwangju 61469, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms17050770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881589PMC
May 2016

Design of a RANK-Mimetic Peptide Inhibitor of Osteoclastogenesis with Enhanced RANKL-Binding Affinity.

Mol Cells 2016 Apr 26;39(4):316-21. Epub 2016 Feb 26.

Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 440-746, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14348/molcells.2016.2286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844938PMC
April 2016

Role of CrkII Signaling in RANKL-Induced Osteoclast Differentiation and Function.

J Immunol 2016 Feb 22;196(3):1123-31. Epub 2015 Dec 22.

Department of Pharmacology, Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju 501-746, Republic of Korea;

View Article

Download full-text PDF

Source
http://www.jimmunol.org/content/early/2015/12/18/jimmunol.15
Web Search
http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1501998
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1501998DOI Listing
February 2016

Signaling Pathways in Osteoclast Differentiation.

Chonnam Med J 2016 Jan 19;52(1):12-7. Epub 2016 Jan 19.

Department of Pharmacology, Chonnam National University Medical School, Gwangju, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4068/cmj.2016.52.1.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742606PMC
January 2016

Dysregulated osteoclastogenesis is related to natural killer T cell dysfunction in rheumatoid arthritis.

Arthritis Rheumatol 2015 Oct;67(10):2639-50

Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/art.39244DOI Listing
October 2015

NRROS Negatively Regulates Osteoclast Differentiation by Inhibiting RANKL-Mediated NF-N:B and Reactive Oxygen Species Pathways.

Mol Cells 2015 Oct 7;38(10):904-10. Epub 2015 Oct 7.

Department of Pharmacology, Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju 501-746, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14348/molcells.2015.0177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625072PMC
October 2015

Mst2 Controls Bone Homeostasis by Regulating Osteoclast and Osteoblast Differentiation.

J Bone Miner Res 2015 Sep 31;30(9):1597-607. Epub 2015 May 31.

Department of Pharmacology, Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbmr.2503DOI Listing
September 2015

NK cell function triggered by multiple activating receptors is negatively regulated by glycogen synthase kinase-3β.

Cell Signal 2015 Sep 27;27(9):1731-41. Epub 2015 May 27.

Department of Biomedical Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, South Korea; Department of Microbiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, South Korea; Cellular Dysfunction Research Center, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, South Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellsig.2015.05.012DOI Listing
September 2015

Comparison of Topical Cyclosporine and Diquafosol Treatment in Dry Eye.

Optom Vis Sci 2015 Sep;92(9):e296-302

*MD †PhD ‡MD, PhD Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju, South Korea (JMY, WC, KCY); Department of Pharmacology, Chonnam National University Medical School, Gwangju, South Korea (NK); and Center for Creative Biomedical Scientists at Chonnam National University, Gwangju, South Korea (NK, KCY).

View Article

Download full-text PDF

Source
http://pdfs.journals.lww.com/optvissci/2015/09000/Comparison
Web Search
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/OPX.0000000000000657DOI Listing
September 2015

Mucosal-associated invariant T cells are numerically and functionally deficient in patients with mycobacterial infection and reflect disease activity.

Tuberculosis (Edinb) 2015 May 21;95(3):267-74. Epub 2015 Mar 21.

Department of Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tube.2015.03.004DOI Listing
May 2015

MicroRNA-26a regulates RANKL-induced osteoclast formation.

Mol Cells 2015 Jan 16;38(1):75-80. Epub 2014 Dec 16.

Department of Pharmacology, Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju 501-746, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14348/molcells.2015.2241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314121PMC
January 2015

Regulation of NFATc1 in Osteoclast Differentiation.

J Bone Metab 2014 Nov 30;21(4):233-41. Epub 2014 Nov 30.

Department of Pharmacology, Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11005/jbm.2014.21.4.233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255043PMC
November 2014

Mucosal-associated invariant T cell deficiency in systemic lupus erythematosus.

J Immunol 2014 Oct 15;193(8):3891-901. Epub 2014 Sep 15.

Department of Rheumatology, Chonnam National University Medical School and Hospital, Gwangju 501-757, Republic of Korea;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1302701DOI Listing
October 2014

GATA4 negatively regulates osteoblast differentiation by downregulation of Runx2.

BMB Rep 2014 Aug;47(8):463-8

Department of Pharmacology; Center for Creative Biomedical Scientists at Chonnam National University, Chonnam National University Medical School, Gwangju 501-746, Korea.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206719PMC
http://dx.doi.org/10.5483/bmbrep.2014.47.8.225DOI Listing
August 2014

Functional deficiency of natural killer cells in acute coronary syndrome is related to ineffective degranulation.

Int J Cardiol 2014 Apr 25;172(3):613-5. Epub 2014 Jan 25.

Department of Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2014.01.083DOI Listing
April 2014

Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclasts.

J Cell Biol 2014 Mar 10;204(6):1063-74. Epub 2014 Mar 10.

Department of Pharmacology, Medical Research Center for Gene Regulation and BK21 plus, Chonnam National University Medical School, Gwangju 501-746, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.201308102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998795PMC
March 2014

Circulating mucosal-associated invariant T cell levels and their cytokine levels in healthy adults.

Exp Gerontol 2014 Jan 20;49:47-54. Epub 2013 Nov 20.

Department of Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2013.11.003DOI Listing
January 2014

SLAT negatively regulates RANKL-induced osteoclast differentiation.

Mol Cells 2013 Sep 29;36(3):252-7. Epub 2013 Aug 29.

Department of Pharmacology, Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju, 501-746, Korea.

View Article

Download full-text PDF

Source
http://link.springer.com/content/pdf/10.1007/s10059-013-0159
Web Search
http://link.springer.com/10.1007/s10059-013-0159-x
Publisher Site
http://dx.doi.org/10.1007/s10059-013-0159-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887978PMC
September 2013

Bone destruction by receptor activator of nuclear factor κB ligand-expressing T cells in chronic gouty arthritis.

Arthritis Res Ther 2011 13;13(5):R164. Epub 2011 Oct 13.

Department of Rheumatology, Research Institute of Medical Sciences, Brain Korea 21, Chonnam National University Medical School and Hospital, 42, Jebong-ro, Dong-gu, Gwangju 501-757, South Korea.

View Article

Download full-text PDF

Source
http://arthritis-research.biomedcentral.com/articles/10.1186
Publisher Site
http://dx.doi.org/10.1186/ar3483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308097PMC
December 2012

Early growth response 2 negatively modulates osteoclast differentiation through upregulation of Id helix-loop-helix proteins.

Bone 2012 Oct 26;51(4):643-50. Epub 2012 Jul 26.

Skeletal Diseases Genome Research Center, Kyungpook National University and Hospital, Daegu 700-412, Republic of Korea.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S875632821200978
Publisher Site
http://dx.doi.org/10.1016/j.bone.2012.07.015DOI Listing
October 2012

Age- and gender-related differences in circulating natural killer T cells and their subset levels in healthy Korean adults.

Hum Immunol 2012 Oct 9;73(10):1011-6. Epub 2012 Aug 9.

Department of Laboratory Medicine, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humimm.2012.07.335DOI Listing
October 2012

The transmembrane adaptor protein, linker for activation of T cells (LAT), regulates RANKL-induced osteoclast differentiation.

Mol Cells 2012 Apr 28;33(4):401-6. Epub 2012 Feb 28.

National Research Laboratory for Regulation of Bone Metabolism and Disease, Department of Pharmacology, Chonnam National University Medical School, Gwangju 501-746, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10059-012-0009-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887798PMC
April 2012

Akt induces osteoclast differentiation through regulating the GSK3β/NFATc1 signaling cascade.

J Immunol 2012 Jan 30;188(1):163-9. Epub 2011 Nov 30.

Chonnam National University Medical School, Gwangju, Korea.

View Article

Download full-text PDF

Source
http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1101254
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1101254DOI Listing
January 2012

Inactivation of glycogen synthase kinase-3β is required for osteoclast differentiation.

J Biol Chem 2011 Nov 23;286(45):39043-50. Epub 2011 Sep 23.

Division of Life and Pharmaceutical Sciences, Center for Cell Signaling and Drug Discovery Research, Ewha Womans University, Seoul 120-750, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M111.256768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234729PMC
November 2011

Numerical and functional deficiencies of natural killer T cells in systemic lupus erythematosus: their deficiency related to disease activity.

Rheumatology (Oxford) 2011 Jun 27;50(6):1054-63. Epub 2011 Jan 27.

Department of Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/rheumatology/keq457DOI Listing
June 2011

RANKL induces NFATc1 acetylation and stability via histone acetyltransferases during osteoclast differentiation.

Biochem J 2011 Jun;436(2):253-62

National Research Laboratory for Regulation of Bone Metabolism and Disease, Medical Research Center for Gene Regulation, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju 501-746, South Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20110062DOI Listing
June 2011

ATP6v0d2 deficiency increases bone mass, but does not influence ovariectomy-induced bone loss.

Biochem Biophys Res Commun 2010 Dec 30;403(1):73-8. Epub 2010 Oct 30.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2010.10.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026595PMC
December 2010

Pim-1 regulates RANKL-induced osteoclastogenesis via NF-κB activation and NFATc1 induction.

J Immunol 2010 Dec 10;185(12):7460-6. Epub 2010 Nov 10.

National Research Laboratory for Regulation of Bone Metabolism and Disease, Medical Research Center for Gene Regulation, Research Institute of Medical Sciences, Brain Korea 21, Chonnam National University Medical School, Gwangju, South Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1000885DOI Listing
December 2010

Structure-based development of a receptor activator of nuclear factor-kappaB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis.

Proc Natl Acad Sci U S A 2010 Nov 8;107(47):20281-6. Epub 2010 Nov 8.

Department of Molecular Cell Biology, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon 440-746, Korea.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.1011686107
Publisher Site
http://dx.doi.org/10.1073/pnas.1011686107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996688PMC
November 2010

MHC class II transactivator negatively regulates RANKL-mediated osteoclast differentiation by downregulating NFATc1 and OSCAR.

Cell Signal 2010 Sep 11;22(9):1341-9. Epub 2010 May 11.

National Research Laboratory for Regulation of Bone Metabolism and Disease, Medical Research Center for Gene Regulation, Research Institute of Medical Sciences, Brain Korea 21, Chonnam National University Medical School, Gwangju, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellsig.2010.05.001DOI Listing
September 2010

Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1.

J Biol Chem 2010 Feb 26;285(8):5224-31. Epub 2009 Dec 26.

National Research Laboratory for Regulation of Bone Metabolism and Disease, Medical Research Center for Gene Regulation, Research Institute of Medical Sciences, Brain Korea 21, Chonnam National University Medical School, Gwangju 501-746, Korea.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M109.042812
Publisher Site
http://dx.doi.org/10.1074/jbc.M109.042812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820750PMC
February 2010

Adrm1 interacts with Atp6v0d2 and regulates osteoclast differentiation.

Biochem Biophys Res Commun 2009 Dec 8;390(3):585-90. Epub 2009 Oct 8.

Departments of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2009.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788059PMC
December 2009

Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis.

Biochem Biophys Res Commun 2009 Oct 30;388(1):131-6. Epub 2009 Jul 30.

Medical Research Center for Gene Regulation and Department of Pharmacology, Chonnam National University Medical School, Gwangju, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2009.07.134DOI Listing
October 2009

Silibinin inhibits osteoclast differentiation mediated by TNF family members.

Mol Cells 2009 Sep;28(3):201-7

National Research Laboratory for Regulation of Bone Metabolism and Disease, Department of Pharmacology, Brain Korea 21, Chonnam National University Medical School, Gwangju, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10059-009-0123-yDOI Listing
September 2009

The mechanism of osteoclast differentiation induced by IL-1.

J Immunol 2009 Aug 8;183(3):1862-70. Epub 2009 Jul 8.

National Research Laboratory for Regulation of Bone Metabolism and Disease, Medical Research Center for Gene Regulation, Brain Korea 21, Chonnam National University Medical School, Gwangju, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.0803007DOI Listing
August 2009

Regulatory mechanism of NFATc1 in RANKL-induced osteoclast activation.

FEBS Lett 2009 Jul 2;583(14):2435-40. Epub 2009 Jul 2.

National Research Laboratory for Regulation of Bone Metabolism and Disease, Medical Research Center for Gene Regulation, Brain Korea 21, Chonnam National University Medical School, 5 Hak-Dong, Dong-Ku, Gwangju 501-746, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.febslet.2009.06.047DOI Listing
July 2009

Identification of LRRc17 as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation.

J Biol Chem 2009 May 31;284(22):15308-16. Epub 2009 Mar 31.

Department of Pathology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M807722200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685711PMC
May 2009

Selective inhibition of RANK blocks osteoclast maturation and function and prevents bone loss in mice.

J Clin Invest 2009 Apr 2;119(4):813-25. Epub 2009 Mar 2.

Division of Life and Pharmaceutical Sciences, Center for Cell Signaling and Drug Discovery Research, Department of Life Science, College of Natural Sciences, Ewha Womans University, Seoul, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI36809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662555PMC
April 2009

Beta-catenin modulates the level and transcriptional activity of Notch1/NICD through its direct interaction.

Biochim Biophys Acta 2009 Feb 22;1793(2):290-9. Epub 2008 Oct 22.

College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 500-757, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2008.10.002DOI Listing
February 2009

Upstream stimulatory factors regulate OSCAR gene expression in RANKL-mediated osteoclast differentiation.

J Mol Biol 2008 Nov 22;383(3):502-11. Epub 2008 Aug 22.

National Research Laboratory for Regulation of Bone Metabolism and Disease, Research Institute Medical Sciences, Chonnam National University Medical School, Dong-Ku, Gwangju 501-746, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmb.2008.08.036DOI Listing
November 2008

Noninvasive real-time imaging of tumors and metastases using tumor-targeting light-emitting Escherichia coli.

Mol Imaging Biol 2008 Jan-Feb;10(1):54-61. Epub 2007 Nov 10.

Laboratory of In Vivo Molecular Imaging, Department of Nuclear Medicine, Chonnam National University Medical School, Gwangju, South Korea.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11307-007-0120-5
Publisher Site
http://dx.doi.org/10.1007/s11307-007-0120-5DOI Listing
September 2008

The tec family tyrosine kinase Btk Regulates RANKL-induced osteoclast maturation.

J Biol Chem 2008 Apr 14;283(17):11526-34. Epub 2008 Feb 14.

Department of Pathology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M708935200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2431049PMC
April 2008

NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP).

Mol Endocrinol 2008 Jan 20;22(1):176-85. Epub 2007 Sep 20.

National Research Laboratory for Regulation of Bone Metabolism and Disease, Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju 501-746, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2007-0237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725751PMC
January 2008

The negative role of IdS in osteoclastogenesis.

Adv Exp Med Biol 2007 ;602:23-31

Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-0-387-72009-8_3DOI Listing
December 2007

Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells.

Blood 2007 May 16;109(9):3706-12. Epub 2007 Jan 16.

Department of Medicine, Division of Hematology-Oncology, University of Pennsylvania School of Medicine, 3600 Spruce Street, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2006-08-041384DOI Listing
May 2007

Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor.

J Immunol 2007 May;178(9):5588-94

Research Institute of Medical Sciences and Medical Research Center for Gene Regulation, Chonnam National University Medical School, Hak-Dong 5, Dong-Ku, Gwangju, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.178.9.5588DOI Listing
May 2007

MafB negatively regulates RANKL-mediated osteoclast differentiation.

Blood 2007 Apr 7;109(8):3253-9. Epub 2006 Dec 7.

Research Institute of Medical Sciences and Medical Research Center for Gene Regulation, Chonnam National University Medical School, Hak-Dong 5, Dong-Ku, Gwangju 501-746, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2006-09-048249DOI Listing
April 2007

Enhancer of polycomb1, a novel homeodomain only protein-binding partner, induces skeletal muscle differentiation.

J Biol Chem 2007 Mar 27;282(10):7700-9. Epub 2006 Dec 27.

Medical Research Center for Gene Regulation, Research Institute of Medical Sciences, and Brain Korea 21 Project, Center for Biomedical Human Resources, Chonnam National University Medical School, Gwangju 501-746, South Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M611198200DOI Listing
March 2007

Ribavirin enhances osteoclast formation through osteoblasts via up-regulation of TRANCE/RANKL.

Mol Cell Biochem 2007 Feb 15;296(1-2):17-24. Epub 2006 Aug 15.

Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11010-006-9293-5DOI Listing
February 2007

v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation.

Nat Med 2006 Dec 26;12(12):1403-9. Epub 2006 Nov 26.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm1514DOI Listing
December 2006

Osteoimmunology: interplay between the immune system and bone metabolism.

Annu Rev Immunol 2006 ;24:33-63

1Department of Pathology and Laboratory Medicine, AFCRI, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

View Article

Download full-text PDF

Source
http://www.annualreviews.org/doi/10.1146/annurev.immunol.24.
Publisher Site
http://dx.doi.org/10.1146/annurev.immunol.24.021605.090646DOI Listing
June 2006

Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation.

Blood 2006 Apr 1;107(7):2686-93. Epub 2005 Dec 1.

Medical Research Center for Gene Regulation, Chonnam National University Medical School, Hak-Dong 5, Dong-Ku, Gwangju 501-746, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2005-07-2798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895380PMC
April 2006

Protective effect of the DNA vaccine encoding the major house dust mite allergens on allergic inflammation in the murine model of house dust mite allergy.

Clin Mol Allergy 2006 Feb 20;4. Epub 2006 Feb 20.

Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1476-7961-4-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402316PMC
February 2006

Selenite-induced apoptosis of osteoclasts mediated by the mitochondrial pathway.

Toxicol Lett 2006 Jan 18;160(2):143-50. Epub 2005 Aug 18.

Laboratory of Cellular and Molecular Biochemistry, School of Life Sciences and Biotechnology, Korea University, Seoul.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxlet.2005.06.019DOI Listing
January 2006

Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding.

Circulation 2006 Jan 27;113(1):51-9. Epub 2005 Dec 27.

Department of Pharmacology, Research Institute of Medical Sciences and Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju, South Korea.

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.105.5
Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.105.559724DOI Listing
January 2006

Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis.

J Biol Chem 2005 Oct 18;280(42):35209-16. Epub 2005 Aug 18.

Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju, 501-746, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M505815200DOI Listing
October 2005

A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation.

Blood 2005 Aug 7;106(3):852-9. Epub 2005 Apr 7.

Division of Molecular Life Sciences and Center for Cell Signaling Research, Ewha Womans University, Seoul, 120-750, Korea.

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-09-36
Publisher Site
http://dx.doi.org/10.1182/blood-2004-09-3662DOI Listing
August 2005

Strength of TRAF6 signalling determines osteoclastogenesis.

EMBO Rep 2005 Feb;6(2):171-6

Department of Pathology & Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, 308 BRB II/III, 421 Curie Boulevard, Philadelphia, Pennsylvania 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.embor.7400345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1299255PMC
February 2005

The role of RANKL (TRANCE/TNFSF11), a tumor necrosis factor family member, in skeletal development: effects of gene knockout and transgenic rescue.

Connect Tissue Res 2003 ;44 Suppl 1:264-71

Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

View Article

Download full-text PDF

Source
January 2004

TRANCE-RANK costimulation is required for IL-12 production and the initiation of a Th1-type response to Leishmania major infection in CD40L-deficient mice.

J Immunol 2003 Nov;171(10):5437-41

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.171.10.5437DOI Listing
November 2003

Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression.

J Biol Chem 2003 Jun 13;278(26):24209-16. Epub 2003 Apr 13.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M302940200DOI Listing
June 2003

Stimulation by toll-like receptors inhibits osteoclast differentiation.

J Immunol 2002 Aug;169(3):1516-23

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.169.3.1516DOI Listing
August 2002

Gene expression profiling of osteoclast differentiation by combined suppression subtractive hybridization (SSH) and cDNA microarray analysis.

DNA Cell Biol 2002 Aug;21(8):541-9

Abramson Family Center Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104-6160, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/104454902320308915DOI Listing
August 2002

A novel member of the leukocyte receptor complex regulates osteoclast differentiation.

J Exp Med 2002 Jan;195(2):201-9

Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193610PMC
http://dx.doi.org/10.1084/jem.20011681DOI Listing
January 2002