Myung-Ju Ahn

Myung-Ju Ahn

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Myung-Ju Ahn

Myung-Ju Ahn

Publications by authors named "Myung-Ju Ahn"

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Genomic landscape of acquired resistance to third-generation EGFR tyrosine kinase inhibitors in EGFR T790M-mutant non-small cell lung cancer.

Cancer 2020 Jun 10;126(11):2704-2712. Epub 2020 Mar 10.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1002/cncr.32809DOI Listing
June 2020

Outstanding clinical efficacy of PD-1/PD-L1 inhibitors for pulmonary pleomorphic carcinoma.

Eur J Cancer 2020 Jun 1;132:150-158. Epub 2020 May 1.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.03.029DOI Listing
June 2020

Benefit of Targeted DNA Sequencing in Advanced Non-Small-Cell Lung Cancer Patients Without EGFR and ALK Alterations on Conventional Tests.

Clin Lung Cancer 2020 May 21;21(3):e182-e190. Epub 2019 Nov 21.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2019.11.006DOI Listing
May 2020

Prevalence of NUT carcinoma in head and neck: Analysis of 362 cases with literature review.

Head Neck 2020 May 6;42(5):924-938. Epub 2020 Jan 6.

Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.1002/hed.26067DOI Listing
May 2020

Prognostic value of SUVmax on 18F-fluorodeoxyglucose PET/CT scan in patients with malignant pleural mesothelioma.

PLoS One 2020 18;15(2):e0229299. Epub 2020 Feb 18.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0229299PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028266PMC
May 2020

Characteristics and outcomes of RET-rearranged Korean non-small cell lung cancer patients in real-world practice.

Jpn J Clin Oncol 2020 May;50(5):594-601

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1093/jjco/hyaa019DOI Listing
May 2020

Entrectinib resistance mechanisms in ROS1-rearranged non-small cell lung cancer.

Invest New Drugs 2020 04 24;38(2):360-368. Epub 2019 May 24.

Division of Hematology and Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.

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http://dx.doi.org/10.1007/s10637-019-00795-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066105PMC
April 2020

Osimertinib for Patients With Leptomeningeal Metastases Associated With EGFR T790M-Positive Advanced NSCLC: The AURA Leptomeningeal Metastases Analysis.

J Thorac Oncol 2020 Apr 27;15(4):637-648. Epub 2019 Dec 27.

Department of Clinical Oncology, State Key Laboratory in Translational Oncology, Chinese University of Hong Kong, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1016/j.jtho.2019.12.113DOI Listing
April 2020

PD-1 inhibitors for non-small cell lung cancer patients with special issues: Real-world evidence.

Cancer Med 2020 Apr 6;9(7):2352-2362. Epub 2020 Feb 6.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1002/cam4.2868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131857PMC
April 2020

Induction chemotherapy followed by concurrent chemoradiotherapy versus CCRT for locally advanced hypopharynx and base of tongue cancer.

Korean J Intern Med 2020 Apr 3. Epub 2020 Apr 3.

Division of Hematology-Oncology, Department of Medicine, , Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3904/kjim.2019.161DOI Listing
April 2020

PD-1 blockade-unresponsive human tumor-infiltrating CD8 T cells are marked by loss of CD28 expression and rescued by IL-15.

Cell Mol Immunol 2020 Apr 24. Epub 2020 Apr 24.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1038/s41423-020-0427-6DOI Listing
April 2020

Junction Location Identifier (JuLI): Accurate Detection of DNA Fusions in Clinical Sequencing for Precision Oncology.

J Mol Diagn 2020 Mar 25;22(3):304-318. Epub 2019 Dec 25.

Samsung Genome Institute, Samsung Medical Center, Seoul, Republic of Korea; Geninus Inc., Seoul, Republic of Korea; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University, Seoul, Republic of Korea; Department of Digital Health, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University, Seoul, Republic of Korea; Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2019.10.015DOI Listing
March 2020

Immune-related adverse events are clustered into distinct subtypes by T-cell profiling before and early after anti-PD-1 treatment.

Oncoimmunology 2020 2;9(1):1722023. Epub 2020 Feb 2.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1080/2162402X.2020.1722023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999841PMC
February 2020

Clinical Characteristics and Outcomes of Non-small Cell Lung Cancer Patients with HER2 Alterations in Korea.

Cancer Res Treat 2020 Jan 26;52(1):292-300. Epub 2019 Jul 26.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://www.e-crt.org/journal/view.php?doi=10.4143/crt.2019.1
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http://dx.doi.org/10.4143/crt.2019.186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962476PMC
January 2020

Osimertinib in Patients with T790M-Positive Advanced Non-small Cell Lung Cancer: Korean Subgroup Analysis from Phase II Studies.

Cancer Res Treat 2020 Jan 23;52(1):284-291. Epub 2019 Jul 23.

Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

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http://dx.doi.org/10.4143/crt.2019.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962491PMC
January 2020

Cancer-Related Stroke: An Emerging Subtype of Ischemic Stroke with Unique Pathomechanisms.

J Stroke 2020 Jan 31;22(1):1-10. Epub 2020 Jan 31.

Department of Hemato-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.5853/jos.2019.02278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005348PMC
January 2020

Characteristics and Clinical Outcomes of Non-small Cell Lung Cancer Patients in Korea With Exon 14 Skipping.

In Vivo 2020 May-Jun;34(3):1399-1406

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

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http://dx.doi.org/10.21873/invivo.11920DOI Listing
January 2020

Improved treatment outcome of pembrolizumab in patients with nonsmall cell lung cancer and chronic obstructive pulmonary disease.

Int J Cancer 2019 11 25;145(9):2433-2439. Epub 2019 Mar 25.

Division of Hematology and Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.1002/ijc.32235DOI Listing
November 2019

Circulating DNAs, a Marker of Neutrophil Extracellular Traposis and Cancer-Related Stroke: The OASIS-Cancer Study.

Stroke 2019 10 9;50(10):2944-2947. Epub 2019 Aug 9.

Translational and Stem Cell Research Laboratory on Stroke, Samsung Medical Center, Seoul, South Korea (O.Y.B., J.-W.C., Y.H.C., M.J.O.).

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http://dx.doi.org/10.1161/STROKEAHA.119.026373DOI Listing
October 2019

Genomic scoring to determine clinical benefit of immunotherapy by targeted sequencing.

Eur J Cancer 2019 10 4;120:65-74. Epub 2019 Sep 4.

Division of Hematology-Oncology, Departments of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Department of Health Sciences and Technology, Samsung Advanced Institute of Health Science and Technology, Sungkyunkwan University, Seoul, South Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049193044
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http://dx.doi.org/10.1016/j.ejca.2019.08.001DOI Listing
October 2019

Efficacy and safety of cisplatin and weekly docetaxel in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.

Korean J Intern Med 2019 Sep 20;34(5):1107-1115. Epub 2018 Jun 20.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3904/kjim.2017.234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718762PMC
September 2019

DNA Damage Response and Repair Pathway Alteration and Its Association With Tumor Mutation Burden and Platinum-Based Chemotherapy in SCLC.

J Thorac Oncol 2019 09 22;14(9):1640-1650. Epub 2019 May 22.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; Department of Health Science and Technology, Samsung Advanced Institute of Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.05.014DOI Listing
September 2019

Comprehensive Clinical and Genetic Characterization of Hyperprogression Based on Volumetry in Advanced Non-Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitor.

J Thorac Oncol 2019 09 11;14(9):1608-1618. Epub 2019 Jun 11.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.05.033DOI Listing
September 2019

Pembrolizumab for Patients With Refractory or Relapsed Thymic Epithelial Tumor: An Open-Label Phase II Trial.

J Clin Oncol 2019 08 15;37(24):2162-2170. Epub 2018 Jun 15.

3Samsung Medical Center, Sunghyunkwan University School of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.1200/JCO.2017.77.3184DOI Listing
August 2019

Paired genomic analysis of squamous cell carcinoma transformed from EGFR-mutated lung adenocarcinoma.

Lung Cancer 2019 08 24;134:7-15. Epub 2019 May 24.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.05.024DOI Listing
August 2019

Predictive and Prognostic Value of F-fluorodeoxyglucose Uptake Combined with Thymidylate Synthase Expression in Patients with Advanced Non-Small Cell Lung Cancer.

Sci Rep 2019 08 21;9(1):12215. Epub 2019 Aug 21.

Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-019-48674-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704155PMC
August 2019

Advanced-Stage Non-Small Cell Lung Cancer: Advances in Thoracic Oncology 2018.

J Thorac Oncol 2019 07 16;14(7):1134-1155. Epub 2019 Apr 16.

Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, Guangzhou, People's Republic of China.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864193028
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http://dx.doi.org/10.1016/j.jtho.2019.03.022DOI Listing
July 2019

Histopathologic characteristics of advanced-stage ROS1-rearranged non-small cell lung cancers.

Pathol Res Pract 2019 Jul 6;215(7):152441. Epub 2019 May 6.

Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2019.152441DOI Listing
July 2019

Prognostic Impact of Longitudinal Monitoring of Radiomic Features in Patients with Advanced Non-Small Cell Lung Cancer.

Sci Rep 2019 06 19;9(1):8730. Epub 2019 Jun 19.

Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1038/s41598-019-45117-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584670PMC
June 2019

Efficacy and Safety of Lorlatinib in Korean Non-Small-Cell Lung Cancer Patients With ALK or ROS1 Rearrangement Whose Disease Failed to Respond to a Previous Tyrosine Kinase Inhibitor.

Clin Lung Cancer 2019 05 31;20(3):215-221. Epub 2018 Dec 31.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15257304183035
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http://dx.doi.org/10.1016/j.cllc.2018.12.020DOI Listing
May 2019

Transthoracic Rebiopsy for Mutation Analysis in Lung Adenocarcinoma: Outcomes and Risk Factors for the Acquisition of Nondiagnostic Specimens in 199 Patients.

Clin Lung Cancer 2019 05 31;20(3):e309-e316. Epub 2018 Dec 31.

Department of Radiology, Samsung Medical Center, Seoul, Korea; Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1016/j.cllc.2018.12.021DOI Listing
May 2019

Impact of EGFR mutation on the clinical efficacy of PD-1 inhibitors in patients with pulmonary adenocarcinoma.

J Cancer Res Clin Oncol 2019 May 21;145(5):1341-1349. Epub 2019 Mar 21.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

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http://dx.doi.org/10.1007/s00432-019-02889-0DOI Listing
May 2019

Combination of Osimertinib with Durvalumab in Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer: Is There Room for Reinvestigation?

Authors:
Myung-Ju Ahn

J Thorac Oncol 2019 05;14(5):766-767

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.03.005DOI Listing
May 2019

Paired whole exome and transcriptome analyses for the Immunogenomic changes during concurrent chemoradiotherapy in esophageal squamous cell carcinoma.

J Immunother Cancer 2019 05 16;7(1):128. Epub 2019 May 16.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-Gu, Seoul, 60351, Republic of Korea.

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https://jitc.biomedcentral.com/articles/10.1186/s40425-019-0
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http://dx.doi.org/10.1186/s40425-019-0609-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524245PMC
May 2019

Efficacy and Safety of Afatinib for EGFR-mutant Non-small Cell Lung Cancer, Compared with Gefitinib or Erlotinib.

Cancer Res Treat 2019 Apr 13;51(2):502-509. Epub 2018 Jun 13.

Division of Hematology-Oncology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2018.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473268PMC
April 2019

Clinical Outcomes of EGFR Exon 20 Insertion Mutations in Advanced Non-small Cell Lung Cancer in Korea.

Cancer Res Treat 2019 Apr 23;51(2):623-631. Epub 2018 Jul 23.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://www.e-crt.org/journal/view.php?doi=10.4143/crt.2018.1
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http://dx.doi.org/10.4143/crt.2018.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473281PMC
April 2019

The First-week Proliferative Response of Peripheral Blood PD-1CD8 T Cells Predicts the Response to Anti-PD-1 Therapy in Solid Tumors.

Clin Cancer Res 2019 04 15;25(7):2144-2154. Epub 2019 Jan 15.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-18-1449DOI Listing
April 2019

Repeat biopsy procedures and T790M rates after afatinib, gefitinib, or erlotinib therapy in patients with lung cancer.

Lung Cancer 2019 04 28;130:87-92. Epub 2019 Jan 28.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.01.012DOI Listing
April 2019

Dosimetric predictors for postoperative pulmonary complications in esophageal cancer following neoadjuvant chemoradiotherapy and surgery.

Radiother Oncol 2019 04 21;133:87-92. Epub 2019 Jan 21.

Department of Radiation Oncology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.radonc.2019.01.005DOI Listing
April 2019

Incidence of brain metastasis in lung adenocarcinoma at initial diagnosis on the basis of stage and genetic alterations.

Lung Cancer 2019 03 28;129:28-34. Epub 2018 Dec 28.

Division of Pulmonology and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.12.027DOI Listing
March 2019

Correlations between metabolic texture features, genetic heterogeneity, and mutation burden in patients with lung cancer.

Eur J Nucl Med Mol Imaging 2019 02 25;46(2):446-454. Epub 2018 Aug 25.

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.

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http://dx.doi.org/10.1007/s00259-018-4138-5DOI Listing
February 2019

Concurrent Genetic Alterations Predict the Progression to Target Therapy in EGFR-Mutated Advanced NSCLC.

J Thorac Oncol 2019 02 1;14(2):193-202. Epub 2018 Nov 1.

Division of Hematology-Oncology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864183338
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http://dx.doi.org/10.1016/j.jtho.2018.10.150DOI Listing
February 2019

Correction to: 33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2018).

Authors:
Sneha Berry Nicolas Giraldo Peter Nguyen Benjamin Green Haiying Xu Aleksandra Ogurtsova Abha Soni Farah Succaria Daphne Wang Charles Roberts Julie Stein Elizabeth Engle Drew Pardoll Robert Anders Tricia Cottrell Janis M Taube Ben Tran Mark Voskoboynik James Kuo Yung-Lue Bang Hyun-Cheo Chung Myung-Ju Ahn Sang-We Kim Ayesh Perera Daniel Freeman Ikbel Achour Raffaella Faggioni Feng Xiao Charles Ferte Charlotte Lemech Funda Meric-Bernstam Theresa Werner Stephen Hodi Wells Messersmith Nancy Lewis Craig Talluto Mirek Dostalek Aiyang Tao Sarah McWhirter Damian Trujillo Jason Luke Chunxiao Xu BoMarelli Jin Qi Guozhong Qin Huakui Yu Molly Jenkins Kin-Ming Lo Joern-Peter Halle Yan Lan Matthew Taylor Nicholas Vogelzang Allen Cohn Daniel Stepan Robert Shumaker Corina Dutcus Matthew Guo Emmett Schmidt Drew Rasco Marcia Brose Nicholas Vogelzang Christopher Di Simone Sharad Jain Donald Richards Carlos Encarnacion Drew Rasco Robert Shumaker Corina Dutcus Daniel Stepan Matthew Guo Emmett Schmidt Matthew Taylor Nicholas Vogelzang Carlos Encarnacion Allen Cohn Christopher Di Simone Drew Rasco Donald Richards Matthew Taylor Corina Dutcus Daniel Stepan Robert Shumaker Matthew Guo Emmett Schmidt James Mier Jeongshin An Yeun-Yeoul Yang Won-Hee Lee Jinho Yang Jong-Kyu Kim Hyun Goo Kim Se Hyun Paek Jun Woo Lee Joohyun Woo Jong Bin Kim Hyungju Kwon Woosung Lim Nam Sun Paik Yoon-Keun Kim Byung-In Moon Filip Janku David Tan Juan Martin-Liberal Shunji Takahashi Ravit Geva Ayca Gucalp Xueying Chen Kulandayan Subramanian Jennifer Mataraza Jennifer Wheler Philippe Bedard

J Immunother Cancer 2019 Feb 13;7(1):46. Epub 2019 Feb 13.

Princess Margaret Cancer Centre, Toronto, ON, Canada.

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http://dx.doi.org/10.1186/s40425-019-0519-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373015PMC
February 2019

Rare Mechanism of Acquired Resistance to Osimertinib in Korean Patients with EGFR-mutated Non-small Cell Lung Cancer.

Cancer Res Treat 2019 Jan 23;51(1):408-412. Epub 2018 May 23.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2018.138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333983PMC
January 2019

Current status of immune checkpoint inhibitors in treatment of non-small cell lung cancer.

Korean J Intern Med 2019 Jan 3;34(1):50-59. Epub 2018 Sep 3.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3904/kjim.2018.179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325449PMC
January 2019

Clinical outcomes of radiation therapy for clinical T4b oesophageal cancer with airway invasion.

Radiat Oncol 2018 Dec 14;13(1):245. Epub 2018 Dec 14.

Department of Thoracic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1186/s13014-018-1196-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295084PMC
December 2018

Phase Ib/II Study of Capmatinib (INC280) Plus Gefitinib After Failure of Epidermal Growth Factor Receptor (EGFR) Inhibitor Therapy in Patients With EGFR-Mutated, MET Factor-Dysregulated Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 11 29;36(31):3101-3109. Epub 2018 Aug 29.

Yi-Long Wu, Guangdong General Hospital and Guangdong Academy of Medical Sciences; Li Zhang, Sun Yat-sen University Cancer Center, Guangdong; Xiaoqing Liu, Affiliated Hospital of the Chinese Academy of Military Medical Sciences, Beijing; Sylvia Zhao and Bin Peng, Novartis Institutes for Biomedical Research, Shanghai, People's Republic of China; Dong-Wan Kim, Seoul National University Hospital; Dae Ho Lee, University of Ulsan College of Medicine; Myung-Ju Ahn, Samsung Medical Center, Seoul, Republic of Korea; James Chih-Hsin Yang, National Taiwan University Hospital, Taipei; Wu-Chou Su, National Cheng Kung University Hospital, Tainan, Taiwan; Johan F. Vansteenkiste, University Hospital KU Leuven, Leuven, Belgium; Enriqueta Felip, Vall d'Hebron University Hospital, Barcelona, Spain; Vincent Chia and Philippe Pultar, Novartis Pharmaceuticals, East Hanover, NJ; Sabine Glaser and Mikhail Akimov, Novartis Pharma AG, Basel, Switzerland; and Daniel S.W. Tan, National Cancer Centre Singapore, Singapore.

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http://dx.doi.org/10.1200/JCO.2018.77.7326DOI Listing
November 2018

Brigatinib versus Crizotinib in ALK-Positive Non-Small-Cell Lung Cancer.

N Engl J Med 2018 11 25;379(21):2027-2039. Epub 2018 Sep 25.

From the University of Colorado Cancer Center, Aurora (D.R.C.); Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine (H.R.K.), Samsung Medical Center (M.-J.A.), and Seoul National University Hospital (D.-W.K.), Seoul, National Cancer Center, Goyang (J.-Y.H.), Seoul National University Bundang Hospital, Seongnam (J.-S.L.), and Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju (K.H.L.) - all in South Korea; National Taiwan University Hospital (J.C.-H.Y.) and the Faculty of Medicine, School of Medicine, National Yang-Ming University (G.-C.C.), Taipei, and the Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung (G.-C.C.) - all in Taiwan; the Ludwig Boltzmann Institute for COPD and Respiratory Epidemiology, Department of Respiratory and Critical Care Medicine, Otto Wagner Hospital, Vienna (M.J.H.); Queen Elizabeth Hospital, Kowloon, Hong Kong (J.Y.-C.L.); Azienda Ospedaliera S. Giuseppe Moscati, Avellino (C.G.), the Scientific Institute of Romagna for the Study and Treatment of Cancer, Meldola (A.D.), Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS Struttura Operativa Complessa Oncologia Medica A, Aviano (A.B.), Thoracic Medical Oncology, Istituto Nazionale Tumori, IRCCS Fondazione G. Pascale, Naples (A.M.), and the Medical Oncology Unit, University Hospital of Parma, Parma (M.T.) - all in Italy; Complejo Hospitalario Universitario de A Coruña, Coruña (R.G.C.), and Vall d'Hebron University Hospital, Barcelona (E.F.) - both in Spain; the Department of Hematology and Oncology, University Department of Internal Medicine-Oncology, Pius-Hospital Medical Campus, University of Oldenburg, Oldenburg, Germany (F.G.); the Department of Medical Oncology, Christie NHS Foundation Trust, and Division of Cancer Sciences, University of Manchester, Manchester (R.C.), and Guy's and St. Thomas' NHS Foundation Trust (S.G.) and Royal Marsden Hospital and the National Heart and Lung Institute, Imperial College London (S.P.), London - all in the United Kingdom; Virginia Cancer Specialists Research Institute and US Oncology Research, The Woodlands, TX (A.S.); Yale Cancer Center, New Haven, CT (S.N.G.); and Millennium Pharmaceuticals, Cambridge, MA (N.G., J.H., D.K.).

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http://dx.doi.org/10.1056/NEJMoa1810171DOI Listing
November 2018

Continuation of gefitinib beyond progression in patients with EGFR mutation-positive non-small-cell lung cancer: A phase II single-arm trial.

Lung Cancer 2018 10 3;124:293-297. Epub 2018 Aug 3.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002183051
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http://dx.doi.org/10.1016/j.lungcan.2018.08.003DOI Listing
October 2018

Exploratory Analysis of Brigatinib Activity in Patients With Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer and Brain Metastases in Two Clinical Trials.

J Clin Oncol 2018 09 16;36(26):2693-2701. Epub 2018 May 16.

D. Ross Camidge, University of Colorado Cancer Center, Aurora, CO; Dong-Wan Kim, Seoul National University Hospital; Myung-Ju Ahn, Samsung Medical Center; Dae Ho Lee, Asan Medical Center, Seoul, South Korea; Marcello Tiseo, University Hospital of Parma, Parma, Italy; Corey J. Langer, University of Pennsylvania, Philadelphia, PA; Alice T. Shaw, Massachusetts General Hospital, Boston; William Reichmann, Jeff Haney, Tim Clackson, and David Kerstein, ARIAD Pharmaceuticals, Cambridge, MA; Rudolf M. Huber, University Hospital of Munich, Munich, Germany; Maximilian J. Hochmair, Otto Wagner Hospital, Vienna, Austria; Lyudmila A. Bazhenova and Kathryn A. Gold, University of California San Diego Moores Cancer Center, La Jolla; Sai-Hong Ignatius Ou, University of California Irvine School of Medicine, Irvine, CA; Howard L. West, Swedish Cancer Institute, Seattle, WA; and Scott N. Gettinger, Yale Cancer Center, New Haven, CT.

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http://ascopubs.org/doi/10.1200/JCO.2017.77.5841
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http://dx.doi.org/10.1200/JCO.2017.77.5841DOI Listing
September 2018

Characteristics and Outcome of ROS1-Positive Non-Small Cell Lung Cancer Patients in Routine Clinical Practice.

J Thorac Oncol 2018 09 5;13(9):1373-1382. Epub 2018 Jun 5.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.05.026DOI Listing
September 2018

CNS Efficacy of Osimertinib in Patients With T790M-Positive Advanced Non-Small-Cell Lung Cancer: Data From a Randomized Phase III Trial (AURA3).

J Clin Oncol 2018 09 30;36(26):2702-2709. Epub 2018 Jul 30.

Yi-Long Wu, Guangdong General Hospital & Guangdong Academy of Medical Sciences, Guangzhou, China; Myung-Ju Ahn, Sungkyunkwan University School of Medicine; Hye Ryun Kim, Yonsei University College of Medicine, Seoul; Ji-Youn Han, National Cancer Center, Goyang, Republic of Korea; Marina Chiara Garassino, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Nobuyuki Katakami, Institute of Biomedical Research and Innovation, Kobe, Japan; Rachel Hodge, Paramjit Kaur, Andrew P. Brown, and Dana Ghiorghiu, AstraZeneca, Cambridge, United Kingdom; Vassiliki A. Papadimitrakopoulou, The University of Texas MD Anderson Cancer Center, Houston, TX; and Tony S.K. Mok, Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1200/JCO.2018.77.9363DOI Listing
September 2018

Transient Asymptomatic Pulmonary Opacities During Osimertinib Treatment and its Clinical Implication.

J Thorac Oncol 2018 08;13(8):1106-1112

Division of Hematology-Oncology, Departments of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.04.038DOI Listing
August 2018

Acquired resistance to AZD9291 as an upfront treatment is dependent on ERK signaling in a preclinical model.

PLoS One 2018 11;13(4):e0194730. Epub 2018 Apr 11.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194730PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895014PMC
July 2018

Phase I Trial of Anti-MET Monoclonal Antibody in MET-Overexpressed Refractory Cancer.

Clin Colorectal Cancer 2018 06 31;17(2):140-146. Epub 2018 Jan 31.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2018.01.005DOI Listing
June 2018

Deciphering Clinicoradiologic Phenotype for Thymidylate Synthase Expression Status in Patients with Advanced Lung Adenocarcinoma Using a Radiomics Approach.

Sci Rep 2018 06 12;8(1):8968. Epub 2018 Jun 12.

Division of Hematology-Oncology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1038/s41598-018-27273-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997691PMC
June 2018

Phase II Study of Crizotinib in East Asian Patients With ROS1-Positive Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 05 29;36(14):1405-1411. Epub 2018 Mar 29.

Yi-Long Wu and Jin-Ji Yang, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou; Shun Lu, Jiao Tong University, Shanghai; Jianying Zhou, First Affiliated Hospital of Zhejiang University, Hangzhou, People's Republic of China; James Chih-Hsin Yang, National Taiwan University Hospital and National Taiwan University Cancer Center, Taipei, Republic of China; Dong-Wan Kim, Seoul National University Hospital; Myung-Ju Ahn, Samsung Medical Center, Seoul, South Korea; Takashi Seto, National Kyushu Cancer Center, Fukuoka; Noboru Yamamoto, National Cancer Center Hospital, Tokyo; Toshiaki Takahashi, Shizuoka Cancer Center, Shizuoka; Takeharu Yamanaka, Yokohama City University School of Medicine, Yokohama; Koichi Goto, National Cancer Center Hospital East, Kashiwa, Japan; Allison Kemner and Debasish Roychowdhury, OxOnc Development, Princeton, NJ; Nirvan Consultants, Lexington, MA; Jolanda Paolini and Tiziana Usari, Pfizer, Milan, Italy; and Keith D. Wilner, Pfizer, La Jolla, CA.

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http://dx.doi.org/10.1200/JCO.2017.75.5587DOI Listing
May 2018

Association of Cancer Cell Type and Extracellular Vesicles With Coagulopathy in Patients With Lung Cancer and Stroke.

Stroke 2018 05 2;49(5):1282-1285. Epub 2018 Apr 2.

From the Departments of Neurology (J.-W.C., M.J.L., G.-M.K., C.-S.C., O.Y.B.)

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http://dx.doi.org/10.1161/STROKEAHA.118.020995DOI Listing
May 2018

Afatinib in heavily pretreated advanced NSCLC patients who progressed following prior gefitinib or erlotinib: Compassionate use program in Korea.

Lung Cancer 2018 05 6;119:36-41. Epub 2018 Mar 6.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.02.020DOI Listing
May 2018

Pazopanib maintenance after first-line etoposide and platinum chemotherapy in patients with extensive disease small-cell lung cancer: a multicentre, randomised, placebo-controlled Phase II study (KCSG-LU12-07).

Br J Cancer 2018 03 30;118(5):648-653. Epub 2018 Jan 30.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea.

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http://dx.doi.org/10.1038/bjc.2017.465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846070PMC
March 2018

Late-Onset Cholecystitis with Cholangitis after Avelumab Treatment in Non-Small Cell Lung Cancer.

J Thorac Oncol 2018 03;13(3):e34-e36

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2017.10.007DOI Listing
March 2018

Temporal and regional distribution of initial recurrence site in completely resected N1-stage II lung adenocarcinoma: The effect of postoperative adjuvant chemotherapy.

Lung Cancer 2018 03 6;117:7-13. Epub 2018 Jan 6.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.01.004DOI Listing
March 2018

Consolidation of immunotherapy becomes new standard of care in unresectable stage III non-small cell lung cancer.

Authors:
Myung-Ju Ahn

J Thorac Dis 2018 Mar;10(3):1205-1206

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.21037/jtd.2018.03.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906269PMC
March 2018

Recurrence dynamics after trimodality therapy (Neoadjuvant concurrent chemoradiotherapy and surgery) in patients with stage IIIA (N2) lung cancer.

Lung Cancer 2018 01 22;115:89-96. Epub 2017 Nov 22.

Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.11.020DOI Listing
January 2018