Publications by authors named "Myung Kyu Lee"

34Publications

Evaluation of Protective Immunity of Peptide Vaccines Composed of a 15-mer N-terminal Matrix Protein 2 and a Helper T-Cell Epitope Derived from Influenza A Virus.

Immune Netw 2019 Aug 23;19(4):e29. Epub 2019 Jul 23.

Bionano Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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August 2019

Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH.

Biochem Biophys Res Commun 2018 05 28;499(3):475-481. Epub 2018 Mar 28.

Department of Biomedical Sciences, BK21-plus Education Program, Seoul National University College of Medicine, Seoul, South Korea; Ischemic/Hypoxic Disease Institute and Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea. Electronic address:

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May 2018

Preparation of siRNA encapsulated nanoliposomes suitable for siRNA delivery by simply discontinuous mixing.

Biochim Biophys Acta Biomembr 2018 Jun 6;1860(6):1318-1325. Epub 2018 Mar 6.

Hazards Monitoring Bionano Research Center, KRIBB, 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, South Korea; Department of Biosystems and Bioengineering, KRIBB School of Biotechnology, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon, South Korea. Electronic address:

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June 2018

Specific capture, recovery and culture of cancer cells using oriented antibody-modified polystyrene chips coated with agarose film.

Colloids Surf B Biointerfaces 2018 Feb 22;162:306-315. Epub 2017 Dec 22.

Hazards Monitoring Bionano Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea; Department of Biosystems and Bioengineering, KRIBB School of Biotechnology, Korea University of Science and Technology(UST), 217 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea. Electronic address:

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February 2018

Covalent and Oriented Surface Immobilization of Antibody Using Photoactivatable Antibody Fc-Binding Protein Expressed in Escherichia coli.

Anal Chem 2016 10 14;88(19):9503-9509. Epub 2016 Sep 14.

Hazards Monitoring Bionano Research Center, ‡Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, and §Department of Nanobiotechnology, University of Science and Technology , 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.

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October 2016

Enhanced tumor-targeted gene delivery by bioreducible polyethylenimine tethering EGFR divalent ligands.

Biomater Sci 2015 Jul 17;3(7):1096-104. Epub 2015 Feb 17.

Center for Self-assembly and Complexity, Institute for Basic Science and Department of Chemistry, Pohang University of Science and Technology (POSTECH) 77 Cheongam-ro, Nam-gu, Pohang 790-784, Republic of Korea.

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July 2015

Purification and characterization of Fab fragments with rapid reaction kinetics against myoglobin.

Biosci Biotechnol Biochem 2015 3;79(5):718-24. Epub 2015 Jan 3.

a Functional Genomic Center , Korea Research Institute of Bioscience & Biotechnology , Daejeon , Republic of Korea.

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May 2016

Refolded scFv antibody fragment against myoglobin shows rapid reaction kinetics.

Int J Mol Sci 2014 Dec 18;15(12):23658-71. Epub 2014 Dec 18.

Medical Proteomics Research Center, Korea Research Institute of Bioscience & Biotechnology, Daejeon 305-806, Korea.

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December 2014

Dependence of filopodia morphology and the separation efficiency of primary CD4⁺ T-lymphocytes on nanopillars.

Anal Chem 2014 Jun 22;86(11):5330-7. Epub 2014 May 22.

Basic Research Laboratory, Department of Semiconductor Science and Technology, Chonbuk National University , Jeonju 561-756, Republic of Korea.

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June 2014

TMPRSS4 induces cancer cell invasion through pro-uPA processing.

Biochem Biophys Res Commun 2014 Mar 14;446(1):1-7. Epub 2014 Jan 14.

Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejon, Republic of Korea. Electronic address:

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March 2014

TMPRSS4 upregulates uPA gene expression through JNK signaling activation to induce cancer cell invasion.

Cell Signal 2014 Feb 24;26(2):398-408. Epub 2013 Aug 24.

Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea; Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea. Electronic address:

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February 2014

Ethanol treatment a Non-extrusion method for asymmetric liposome size optimization.

Daru 2013 Apr 18;21(1):32. Epub 2013 Apr 18.

Bionanotechnology Research Center, KRIBB, 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806, Republic of Korea.

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April 2013

Novel cell penetrating peptides with multiple motifs composed of RGD and its analogs.

Biochem Biophys Res Commun 2013 Mar 4;432(2):359-64. Epub 2013 Feb 4.

Bionanotechnology Research Center, KRIBB, 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806, Republic of Korea.

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March 2013

Differential in vitro and cellular effects of iron chelators for hypoxia inducible factor hydroxylases.

J Cell Biochem 2013 Apr;114(4):864-73

Bionanotechnology Research Center, KRIBB, Gwahak-ro, Yuseong-gu, Daejeon 305-806, Republic of Korea.

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April 2013

Asymmetric liposome particles with highly efficient encapsulation of siRNA and without nonspecific cell penetration suitable for target-specific delivery.

Biochim Biophys Acta 2012 Jul;1818(7):1633-41

Bionanotechnology Research Center, KRIBB, 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806, Republic of Korea.

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July 2012

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.

J Biol Chem 2011 Apr 18;286(15):13041-51. Epub 2011 Feb 18.

Nuffield Department of Clinical Medicine, Henry Wellcome Building for Molecular Physiology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom.

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April 2011

Structure-based virtual screening approach to the discovery of novel inhibitors of factor-inhibiting HIF-1: identification of new chelating groups for the active-site ferrous ion.

Bioorg Med Chem 2009 Nov 20;17(22):7769-74. Epub 2009 Sep 20.

Department of Bioscience and Biotechnology, Sejong University, 98 Kunja-Dong, Kwangjin-Ku, Seoul 143-747, Republic of Korea.

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November 2009

Nutlin-3, an Hdm2 antagonist, inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated inactivation of HIF-1alpha.

Carcinogenesis 2009 Oct 20;30(10):1768-75. Epub 2009 Aug 20.

Department of Pharmacology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Korea.

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October 2009

A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1{alpha}.

Mol Cancer Ther 2008 Dec;7(12):3729-38

Department of Pharmacology, Seoul National University College of Medicine, Seoul, Korea.

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December 2008

Monoclonal antibody-based screening assay for factor inhibiting hypoxia-inducible factor inhibitors.

J Biomol Screen 2008 Jul 19;13(6):494-503. Epub 2008 Jun 19.

Systemic Proteomics Research Center, KRIBB, Yuseong, Daejeon, Korea.

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July 2008

Solution conformation of an immunodominant epitope in the hepatitis B virus preS2 surface antigen.

Antiviral Res 2006 Dec 7;72(3):207-15. Epub 2006 Jul 7.

Molecular Cancer Research Center, Division of Molecular Therapeutics, Korea Research Institute of Bioscience and Biotechnology, Yusong P.O. Box 115, Daejon, Korea.

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December 2006

Structure-activity relationships of anti-HIV-1 peptides with disulfide linkage between D- and L-cysteine at positions i and i+3, respectively, derived from HIV-1 gp41 C-peptide.

Exp Mol Med 2006 Feb;38(1):18-26

Systemic Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, PO Box 115, Yusong, Daejeon 305-600, Korea.

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February 2006

Stronger anti-HIV-1 activity of C-peptide derived from HIV-1 89.6 gp41 C-terminal heptad repeated sequence.

Peptides 2005 Nov;26(11):2175-81

Systemic Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, Daejon 305-600, Republic of Korea.

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November 2005

High-throughput screening method of inhibitors that block the interaction between 2 helical regions of HIV-1 gp41.

J Biomol Screen 2005 Feb;10(1):13-9

Division of Life Sciences, Korea Institute of Science and Technology, Seoul, Korea.

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February 2005

Role of amino acid residues within the disulfide loop of thanatin, a potent antibiotic peptide.

J Biochem Mol Biol 2002 May;35(3):291-6

Proteome Research Laboratory, Korea Research Institute of Bioscience and Biotechnology, Yusong, P.O. Box 115, Taejon 305-600, Korea.

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May 2002

A vector system for introducing foreign HIV-1 env genes and pseudotyping of MuLV particles with the recombinant HIV-1 envelope proteins for anti-HIV-1 assay.

Antiviral Res 2002 Feb;53(2):99-111

Proteome Research Laboratory, Peptide Engineering National Research Laboratory, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, 305-600, Taejon, South Korea.

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February 2002