Publications by authors named "Musa Mhlanga"

41Publications

The Human Cell Atlas and equity: lessons learned.

Nat Med 2020 Oct;26(10):1509-1511

Institute for Medical Engineering & Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41591-020-1100-4DOI Listing
October 2020

Pinpointing Cell Identity in Time and Space.

Front Mol Biosci 2020 14;7:209. Epub 2020 Aug 14.

Division of Chemical, Systems & Synthetic Biology, Faculty of Health Sciences, Institute of Infectious Disease & Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fmolb.2020.00209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456825PMC
August 2020

Visualization of Chromatin Dynamics by Live Cell Microscopy Using CRISPR/Cas9 Gene Editing and ANCHOR Labeling.

Methods Mol Biol 2021 ;2157:197-212

Division of Chemical, Systems and Synthetic Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1007/978-1-0716-0664-3_11DOI Listing
January 2021

Super-beacons: Open-source probes with spontaneous tuneable blinking compatible with live-cell super-resolution microscopy.

Traffic 2020 05 30;21(5):375-385. Epub 2020 Mar 30.

MRC-Laboratory for Molecular Cell Biology, University College London, London, UK.

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http://dx.doi.org/10.1111/tra.12728DOI Listing
May 2020

Advances in understanding molecular regulation of innate immune memory.

Curr Opin Cell Biol 2020 04 25;63:68-75. Epub 2020 Jan 25.

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, 6500HB, Nijmegen, the Netherlands; Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, 6525, GA, Nijmegen, the Netherlands; Department for Immunology & Metabolism, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.

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http://dx.doi.org/10.1016/j.ceb.2019.12.006DOI Listing
April 2020

Targeting innate immunity for tuberculosis vaccination.

J Clin Invest 2019 09;129(9):3482-3491

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.1172/JCI128877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715374PMC
September 2019

The lncRNA Connection Between Cellular Metabolism and Epigenetics in Trained Immunity.

Front Immunol 2018 29;9:3184. Epub 2019 Jan 29.

Division of Chemical, Systems & Synthetic Biology, Department of Integrative Biomedical Sciences, Faculty of Health Sciences, Institute of Infectious Disease & Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fimmu.2018.03184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361822PMC
October 2019

Lnc-ing Trained Immunity to Chromatin Architecture.

Front Cell Dev Biol 2019 24;7. Epub 2019 Jan 24.

Division of Chemical, Systems & Synthetic Biology, Department of Integrative Biomedical Sciences, Faculty of Health Sciences, Institute of Infectious Disease & Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fcell.2019.00002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353842PMC
January 2019

Transcriptionally induced enhancers in the macrophage immune response to Mycobacterium tuberculosis infection.

BMC Genomics 2019 Jan 22;20(1):71. Epub 2019 Jan 22.

Massey University, Institute of Natural and Mathematical Sciences, Albany, Auckland, New Zealand.

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http://dx.doi.org/10.1186/s12864-019-5450-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341744PMC
January 2019

Publisher Correction: Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments.

Nat Genet 2019 02;51(2):364

Gene Expression and Biophysics Group, Division of Chemical, Systems and Synthetic Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1038/s41588-018-0341-3DOI Listing
February 2019

Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments.

Nat Genet 2019 01 10;51(1):138-150. Epub 2018 Dec 10.

Gene Expression and Biophysics Group, Division of Chemical, Systems and Synthetic Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1038/s41588-018-0298-2DOI Listing
January 2019

Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA.

Front Cell Infect Microbiol 2018 3;8:263. Epub 2018 Aug 3.

Gene Expression and Biophysics Group, Synthetic Biology ERA, Council for Scientific and Industrial Research (CSIR), Pretoria, South Africa.

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http://dx.doi.org/10.3389/fcimb.2018.00263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086015PMC
August 2019

Genome-wide profiling of transcribed enhancers during macrophage activation.

Epigenetics Chromatin 2017 10 23;10(1):50. Epub 2017 Oct 23.

Institute of Natural and Mathematical Sciences, Massey University, Albany, Auckland, 0632, New Zealand.

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http://dx.doi.org/10.1186/s13072-017-0158-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654053PMC
October 2017

The emerging molecular biology toolbox for the study of long noncoding RNA biology.

Epigenomics 2017 10 6;9(10):1317-1327. Epub 2017 Sep 6.

Gene Expression & Biophysics Group, Biosciences, CSIR, Pretoria, Gauteng, South Africa.

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http://dx.doi.org/10.2217/epi-2017-0062DOI Listing
October 2017

Lnc-ing inflammation to disease.

Biochem Soc Trans 2017 08 7;45(4):953-62. Epub 2017 Jul 7.

Division of Chemical Systems & Synthetic Biology, Institute for Infectious Disease & Molecular Medicine (IDM), Faculty of Health Sciences, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town 7925, South Africa

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http://dx.doi.org/10.1042/BST20160377DOI Listing
August 2017

Enhancer-Derived lncRNAs Regulate Genome Architecture: Fact or Fiction?

Trends Genet 2017 06 27;33(6):375-377. Epub 2017 Mar 27.

Division of Chemical, Systems, and Synthetic Biology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Gene Expression and Biophysics Group, Biomedical Translational Research Initiative (BTRI), Council for Scientific and Industrial Research (CSIR) Biosciences, Pretoria, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2017.03.004DOI Listing
June 2017

Stability and structural properties of gene regulation networks with coregulation rules.

J Theor Biol 2017 05 17;420:304-317. Epub 2016 Nov 17.

Gene Expression and Biophysics group, Council for Scientific and Industrial Research, Pretoria, South Africa; Division of Chemical Systems and Synthetic Biology, Faculty of Health Sciences, University of Cape Town, South Africa; Unidade de Biofisica e Expressão Genética, Instituto de Medicina Molecular, Universidade de Lisboa, Portugal.

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http://dx.doi.org/10.1016/j.jtbi.2016.10.020DOI Listing
May 2017

Visualization of Enhancer-Derived Noncoding RNA.

Methods Mol Biol 2017 ;1468:19-32

Gene Expression and Biophysics Group, Synthetic Biology ERA, CSIR, Box 395, Pretoria, 0001, South Africa.

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http://dx.doi.org/10.1007/978-1-4939-4035-6_3DOI Listing
January 2018

Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti.

Nat Commun 2016 09 2;7:12629. Epub 2016 Sep 2.

Faculty of Health Sciences, Division of Chemical Systems and Synthetic Biology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Observatory, Cape Town, Western Cape 7925, South Africa.

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http://www.nature.com/articles/ncomms12629
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http://dx.doi.org/10.1038/ncomms12629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025789PMC
September 2016

Non-coding RNAs and HIV: viral manipulation of host dark matter to shape the cellular environment.

Front Genet 2015 26;6:108. Epub 2015 Mar 26.

Gene Expression and Biophysics Group, Synthetic Biology Emerging Research Area, Council for Scientific and Industrial Research, Pretoria South Africa ; Gene Expression and Biophysics Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon Portugal.

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http://dx.doi.org/10.3389/fgene.2015.00108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374539PMC
April 2015

lncRNA and gene looping: what's the connection?

Transcription 2014 ;5(3):e28658

a Gene Expression and Biophysics Group, Synthetic Biology Emerging Research Area, Biosciences Unit, Council for Scientific and Industrial Research; Pretoria, Gauteng, South Africa.

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http://dx.doi.org/10.4161/trns.28658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215167PMC
October 2015

Nanoscopic Localization of Surface-Exposed Antigens of Borrelia burgdorferi.

Microsc Microanal 2015 Jun 5;21(3):680-8. Epub 2015 Mar 5.

1Department of Infectious Diseases - Parasitology,Im Neuenheimer Feld 324,University of Heidelberg Medical School,69120, Heidelberg,Germany.

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http://dx.doi.org/10.1017/S1431927615000318DOI Listing
June 2015

Are genes switched on when they kiss?

Nucleus 2014 Mar-Apr;5(2):103-12. Epub 2014 Feb 25.

Gene Expression and Biophysics Group; Synthetic Biology Emerging Research Area; Biosciences Unit; Council for Scientific and Industrial Research; Pretoria, South Africa; Unidade de Biofísica e Expressão Genética; Instituto de Medicina Molecular; Faculdade de Medicina; Universidade de Lisboa; Lisboa, Portugal.

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http://dx.doi.org/10.4161/nucl.28352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049915PMC
January 2015

TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures.

J Cell Biol 2014 Jan;204(2):231-45

Unité de Signalisation Moléculaire et Activation Cellulaire and 2 Laboratoire Trafic Membranaire et Division Cellulaire, Institut Pasteur, Centre National de la Recherche Scientifique URA 2582, Paris 75015, France.

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http://www.jcb.org/lookup/doi/10.1083/jcb.201307172
Publisher Site
http://dx.doi.org/10.1083/jcb.201307172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897181PMC
January 2014

Chromosomal contact permits transcription between coregulated genes.

Cell 2013 Oct 24;155(3):606-20. Epub 2013 Oct 24.

Gene Expression and Biophysics Group, Synthetic Biology Emerging Research Area, Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, Gauteng 0001, South Africa.

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http://dx.doi.org/10.1016/j.cell.2013.09.051DOI Listing
October 2013

PALM and STORM: unlocking live-cell super-resolution.

Biopolymers 2011 May 19;95(5):322-31. Epub 2011 Jan 19.

Unidade de Biofisica e Expressão Genetica, Instituto de Medicina Molecular, Faculdade de Medicina Universidade de Lisboa, Lisboa, Portugal.

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http://dx.doi.org/10.1002/bip.21586DOI Listing
May 2011

Transcriptome dysregulation by anthrax lethal toxin plays a key role in induction of human endothelial cell cytotoxicity.

Cell Microbiol 2010 Jul 20;12(7):891-905. Epub 2010 May 20.

INSERM, U895, Centre Méditerranéen de Médecine Moléculaire, C3M, Nice, 06204 Cedex 3, France.

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http://dx.doi.org/10.1111/j.1462-5822.2010.01438.xDOI Listing
July 2010

High-throughput SNP genotyping: combining tag SNPs and molecular beacons.

Methods Mol Biol 2009 ;578:255-76

Department of Human Genetics, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1007/978-1-60327-411-1_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121513PMC
December 2009

PALM and STORM: what hides beyond the Rayleigh limit?

Biotechnol J 2009 Jun;4(6):846-57

Gene Expression and Biophysics Unit, Instituto de Medicina Molecular, Faculdade de Medicina Universidade de Lisboa, Lisbon, Portugal.

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http://dx.doi.org/10.1002/biot.200900024DOI Listing
June 2009

Novel inner membrane retention signals in Pseudomonas aeruginosa lipoproteins.

J Bacteriol 2008 Sep 18;190(18):6119-25. Epub 2008 Jul 18.

University of Calgary, Department of Microbiology & Infectious Diseases, 3330 Hospital Dr. NW, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1128/JB.00603-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546801PMC
September 2008

Using tRNA-linked molecular beacons to image cytoplasmic mRNAs in live cells.

Nat Protoc 2006 ;1(3):1392-8

Public Health Research Institute, 225 Warren Street, Newark, New Jersey 07103, USA.

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http://dx.doi.org/10.1038/nprot.2006.242DOI Listing
June 2007

tRNA-linked molecular beacons for imaging mRNAs in the cytoplasm of living cells.

Nucleic Acids Res 2005 4;33(6):1902-12. Epub 2005 Apr 4.

Department of Molecular Genetics, Public Health Research Institute 225 Warren Street, Newark, NJ 07103, USA.

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http://dx.doi.org/10.1093/nar/gki302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1074395PMC
April 2005

Visualizing the distribution and transport of mRNAs in living cells.

Proc Natl Acad Sci U S A 2003 Nov 28;100(23):13308-13. Epub 2003 Oct 28.

Department of Molecular Genetics, Public Health Research Institute, 225 Warren Street, Newark, NJ 07103, USA.

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http://dx.doi.org/10.1073/pnas.2233244100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC263795PMC
November 2003