Murry W Wynes

Murry W Wynes

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Murry W Wynes

Murry W Wynes

Publications by authors named "Murry W Wynes"

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A miRNA Panel Predicts Sensitivity of FGFR Inhibitor in Lung Cancer Cell Lines.

Clin Lung Cancer 2018 09 28;19(5):450-456. Epub 2018 Jun 28.

Department of Medicine, Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2018.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339511PMC
September 2018

Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology.

Arch Pathol Lab Med 2018 Mar 22;142(3):321-346. Epub 2018 Jan 22.

From the Departments of Pathology (Drs Lindeman and Sholl) and Medicine (Dr Kwiatkowski), Brigham and Women's Hospital, Boston, Massachusetts; the Cancer Center (Dr Bernicker) and the Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas (Dr Cagle); the Department of Pathology, University of Colorado School of Medicine, Denver (Dr Aisner); the Diagnostic and Molecular Pathology Laboratory (Dr Arcila) and the Molecular Diagnostics Service (Dr Ladanyi), Memorial Sloan Kettering Cancer Center, New York, New York; the Department of Pathology & Medicine, Pulmonary, Critical Care and Sleep Medicine, New York, New York (Dr Beasley); the Pathology and Laboratory Quality Center, College of American Pathologists, Northfield, Illinois (Mss Colasacco and Ventura); the Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania (Dr Dacic); the Department of Medicine and Pathology, University of Colorado, Denver (Dr Hirsch); the Department of Pathology, University of Aberdeen, Aberdeen, Scotland (Dr Kerr); the Department of Molecular Pathology, Roswell Park Cancer Institute, Buffalo, New York (Dr Nowak); the Clinical and Scientific Affairs Division, Association for Molecular Pathology, Bethesda, Maryland (Dr Temple-Smolkin); the Molecular Therapeutics and Biomarkers Laboratory, Peter Maccallum Cancer Center, Melbourne, Australia (Dr Solomon); the Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands (Dr Thunnissen); the Department of Laboratory Medicine and Pathobiology, Princess Margaret Cancer Center, Toronto, Ontario, Canada (Dr Tsao); Scientific Affairs, International Association for the Study of Lung Cancer, Aurora, Colorado (Dr Wynes); and the Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan (Dr Yatabe). Dr Souter is in private practice in Wellanport, Ontario, Canada.

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http://dx.doi.org/10.5858/arpa.2017-0388-CPDOI Listing
March 2018

Access to Cancer Specialist Care and Treatment in Patients With Advanced Stage Lung Cancer.

Clin Lung Cancer 2017 11 26;18(6):640-650.e2. Epub 2017 Apr 26.

Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.cllc.2017.04.010DOI Listing
November 2017

Independent validation test of the vote-counting strategy used to rank biomarkers from published studies.

Biomark Med 2015 30;9(8):751-61. Epub 2015 Jul 30.

Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

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http://dx.doi.org/10.2217/BMM.15.39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770796PMC
May 2016

FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.

Clin Cancer Res 2014 Jun 25;20(12):3299-309. Epub 2014 Apr 25.

Authors' Affiliations: Departments of Medicine, Pathology, Craniofacial Biology, and Biostatistics and Informatics, University of Colorado Anschutz Medical Campus, Aurora, Colorado; ARIAD Pharmaceuticals, Inc., Cambridge, Massachusetts; Medical University of Gdańsk, Poland; and Department of Prostate Cancer Research, Institute of Pathology, University Hospital of Bonn, Bonn, Germany

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062100PMC
June 2014

An international interpretation study using the ALK IHC antibody D5F3 and a sensitive detection kit demonstrates high concordance between ALK IHC and ALK FISH and between evaluators.

J Thorac Oncol 2014 May;9(5):631-8

*Department of Medicine, Division of Medical Oncology, University of Colorado, Aurora, Colorado; †Department of Pathology Brigham and Women's Hospital, Boston, Massachusetts; ‡Institute of Pathology, Charité University Hospital Berlin, Germany; §Department of Pathology and Medical Biology, University of Groningen, University Medical Centre Groningen, The Netherlands; ‖Princess Margaret Hospital, University Health Network, University of Toronto, Ontario, Canada; ¶Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Kanokoden, Chikusa-ku, Nagoya, Japan; #Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio; ** Department of Pathology, University of Colorado, Aurora, Colorado; and ††University of Colorado Comprehensive Cancer Center, Aurora, Colorado.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864153027
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http://dx.doi.org/10.1097/JTO.0000000000000115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186652PMC
May 2014

Contributions of KRAS and RAL in non-small-cell lung cancer growth and progression.

J Thorac Oncol 2013 Dec;8(12):1492-501

Departments of *Surgery, †Pharmacology, ‖Biostatistics and Informatics, #Pathology, and ‡Division of Medical Oncology, University of Colorado, Aurora, Colorado; ¶University of Colorado Comprehensive Cancer Center, Aurora, Colorado; and §Department of Medicine, National Jewish Health, Denver, Colorado.

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http://dx.doi.org/10.1097/JTO.0000000000000007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934792PMC
December 2013

Insulin-like growth factor-1 receptor (IGF-1R) as a biomarker for resistance to the tyrosine kinase inhibitor gefitinib in non-small cell lung cancer.

Cell Oncol (Dordr) 2013 Jul 26;36(4):277-88. Epub 2013 Apr 26.

Department of Medicine/Medical Oncology, University of Colorado Cancer Center, UC Denver, 12801 E 17th Ave, Mail Stop 8177, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1007/s13402-013-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186686PMC
July 2013

The role of anaplastic lymphoma kinase inhibitors in the treatment of advanced nonsmall cell lung cancer.

Curr Opin Oncol 2013 Mar;25(2):121-9

University of Colorado Cancer Center, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1097/CCO.0b013e32835d8175DOI Listing
March 2013

The mTOR pathway in lung cancer and implications for therapy and biomarker analysis.

J Thorac Oncol 2012 Jun;7(6):947-53

Division of Medical Oncology and Pathology, University of Colorado Denver, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1097/JTO.0b013e31825581bdDOI Listing
June 2012

The tissue is the issue: personalized medicine for non-small cell lung cancer.

Clin Cancer Res 2010 Oct 5;16(20):4909-11. Epub 2010 Oct 5.

University of Colorado Cancer Center, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-2005DOI Listing
October 2010

Early detection and screening of lung cancer.

Expert Rev Mol Diagn 2010 Sep;10(6):799-815

University of Colorado Denver, Anschutz Medical Campus, 12801 East 17th Avenue, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1586/erm.10.60DOI Listing
September 2010

Predictive and prognostic markers for epidermal growth factor receptor inhibitor therapy in non-small cell lung cancer.

Ther Adv Med Oncol 2009 Nov;1(3):137-44

Division of Medical Oncology, University of Colorado Denver, Aurora, CO, USA.

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http://dx.doi.org/10.1177/1758834009347923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125998PMC
November 2009

TNF-alpha sensitizes normal and fibrotic human lung fibroblasts to Fas-induced apoptosis.

Am J Respir Cell Mol Biol 2006 Mar 4;34(3):293-304. Epub 2005 Nov 4.

Program in Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA.

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http://dx.doi.org/10.1165/rcmb.2005-0155OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644194PMC
March 2006

Transcription of macrophage IGF-I exon 1 is positively regulated by the 5'-untranslated region and negatively regulated by the 5'-flanking region.

Am J Physiol Lung Cell Mol Physiol 2005 Jun 28;288(6):L1089-98. Epub 2005 Jan 28.

Program in Cell Biology, Dept. of Pediatrics, Neustadt Rm. D405, National Jewish Medical and Research Center, 1400 Jackson St., Denver, CO 80206, USA.

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http://dx.doi.org/10.1152/ajplung.00352.2004DOI Listing
June 2005

Human insulin-like growth factor-IA expression in transgenic mice promotes adenomatous hyperplasia but not pulmonary fibrosis.

Am J Physiol Lung Cell Mol Physiol 2005 May 23;288(5):L805-12. Epub 2004 Dec 23.

Program in Cell Biology, Department of pediatrics, National Jewish Medical and Research Center, 1400 Jackson St., Denver, CO 80206, USA.

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http://ajplung.physiology.org/content/ajplung/288/5/L805.ful
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http://ajplung.physiology.org/cgi/doi/10.1152/ajplung.00420.
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http://dx.doi.org/10.1152/ajplung.00420.2004DOI Listing
May 2005

IL-4-induced macrophage-derived IGF-I protects myofibroblasts from apoptosis following growth factor withdrawal.

J Leukoc Biol 2004 Nov 17;76(5):1019-27. Epub 2004 Aug 17.

Program of Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA.

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http://dx.doi.org/10.1189/jlb.0504288DOI Listing
November 2004

Induction of macrophage insulin-like growth factor-I expression by the Th2 cytokines IL-4 and IL-13.

J Immunol 2003 Oct;171(7):3550-9

Program in Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA.

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http://www.jimmunol.org/content/171/7/3550.full.pdf
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http://dx.doi.org/10.4049/jimmunol.171.7.3550DOI Listing
October 2003