Publications by authors named "Murray W Huff"

69Publications

Naringenin enhances the regression of atherosclerosis induced by a chow diet in Ldlr mice.

Atherosclerosis 2019 07 9;286:60-70. Epub 2019 May 9.

Molecular Medicine, Robarts Research Institute, The University of Western Ontario, 1151 Richmond St N., London, Ontario, N6A 5B7, Canada; Department of Biochemistry, The University of Western Ontario, 1151 Richmond St N., London, Ontario, N6A 5B7, Canada; Department of Medicine, The University of Western Ontario, 1151 Richmond St N., London, Ontario, N6A 5B7, Canada. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00219150193041
Publisher Site
http://dx.doi.org/10.1016/j.atherosclerosis.2019.05.009DOI Listing
July 2019

Naringenin Supplementation to a Chow Diet Enhances Energy Expenditure and Fatty Acid Oxidation, and Reduces Adiposity in Lean, Pair-Fed Ldlr Mice.

Mol Nutr Food Res 2019 03 2;63(6):e1800833. Epub 2019 Jan 2.

Molecular Medicine, Robarts Research Institute, The University of Western Ontario, 1151 Richmond St N., London, Ontario, N6A 5B7, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mnfr.201800833DOI Listing
March 2019

Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient ( and ) Yucatan Miniature Pigs.

Arterioscler Thromb Vasc Biol 2018 05 15;38(5):1178-1190. Epub 2018 Feb 15.

From the Robarts Research Institute (A.C.B., D.E.T., B.G.S., J.Y.E., C.G.S., J.G.P., M.W.H.)

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.117.310676DOI Listing
May 2018

Knockdown of Δ-5 Fatty Acid Desaturase Is More Than Just a Fad.

Arterioscler Thromb Vasc Biol 2018 01;38(1):6-8

From the Robarts Research Institute, London, Ontario, Canada; and Department of Medicine and Department of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.117.310382DOI Listing
January 2018

Prevention of Diet-Induced Metabolic Dysregulation, Inflammation, and Atherosclerosis in Mice by Treatment With the ATP-Citrate Lyase Inhibitor Bempedoic Acid.

Arterioscler Thromb Vasc Biol 2017 04 2;37(4):647-656. Epub 2017 Feb 2.

From the Molecular Medicine Research Laboratory, Robarts Research Institute (J.P.S., A.C.B., B.G.S., D.E.T., C.G.S., J.Y.E., M.W.H.), Department of Biochemistry (J.P.S., A.C.B., M.W.H.), and Department of Medicine (D.E.T., C.G.S., J.Y.E., M.W.H.), The University of Western Ontario, London, Canada; and Esperion Therapeutics Inc, Ann Arbor, MI (S.L.P., R.S.N.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.116.308963DOI Listing
April 2017

ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia.

Curr Opin Lipidol 2017 Apr;28(2):193-200

aDepartment of Biochemistry bDepartment of Medicine cRobarts Research Institute, The University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOL.0000000000000390DOI Listing
April 2017

Polygenic Versus Monogenic Causes of Hypercholesterolemia Ascertained Clinically.

Arterioscler Thromb Vasc Biol 2016 12 20;36(12):2439-2445. Epub 2016 Oct 20.

From the Robarts Research Institute (J.W., J.S.D., M.R.B., J.F.R., A.D.M., A.A.D., H.C., M.W.H., R.A.H.), Department of Biochemistry (J.S.D., M.A., A.A.D., M.W.H., R.A.H.), and Department of Medicine (P.J.Z., M.W.H., R.A.H.), Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada; Faculté de Médicine, Université de Montréal, Québec, Canada (M.-P.D., G.L., J.-C.T.); and Montréal Heart institute, Québec, Canada (D.R., C.L.-K., M.-P.D., G.L., J.-C.T.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.116.308027DOI Listing
December 2016

PCSK9: Regulation and Target for Drug Development for Dyslipidemia.

Annu Rev Pharmacol Toxicol 2017 01 8;57:223-244. Epub 2016 Aug 8.

Department of Biochemistry, Robarts Research Institute, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada N6A 5B7; email: , , ,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-pharmtox-010716-104944DOI Listing
January 2017

Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis.

Annu Rev Nutr 2016 07 4;36:275-99. Epub 2016 May 4.

Department of Biochemistry, University of Western Ontario, London, ON, Canada N6A 5B7; email: ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-nutr-071715-050718DOI Listing
July 2016

Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21.

Endocrinology 2015 Jun 16;156(6):2087-102. Epub 2015 Mar 16.

Department of Vascular Biology (J.M.A., E.E.M., A.C.B., B.G.S., D.E.T., S.S.C., C.G.S., M.W.H.) and Imaging Research Laboratories (M.D.), Robarts Research Institute, London, Ontario, Canada N6A 5B7; Children's Health Research Institute and Departments of Paediatrics, Physiology and Pharmacology, and Oncology (C.L.P.); Departments of Biochemistry (J.M.A., E.E.M., A.C.B., S.S.C., M.W.H.), Medical Biophysics (M.D.) and Medicine (D.E.T., C.G.S., M.W.H.), The University of Western Ontario, London, Ontario, Canada N6A 5B7; and Lilly Research Laboratories (A.C.A., A.K.), Division of Eli Lilly and Company, Indianapolis, Indiana 46285.

View Article

Download full-text PDF

Source
https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
Publisher Site
http://dx.doi.org/10.1210/en.2014-2003DOI Listing
June 2015

Can a vascular smooth muscle-derived foam-cell really change its spots?

Arterioscler Thromb Vasc Biol 2015 Mar;35(3):492-5

From the Robarts Research Institute and Departments of Medicine, Biophysics and Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.115.305225DOI Listing
March 2015

G-protein estrogen receptor as a regulator of low-density lipoprotein cholesterol metabolism: cellular and population genetic studies.

Arterioscler Thromb Vasc Biol 2015 Jan 13;35(1):213-21. Epub 2014 Nov 13.

From the Robarts Research Institute (Y.H., Q.D., M.R.B., A.D.M., M.W.H., R.G., R.A.H., R.D.F.) and Departments of Medicine (M.W.H., R.G., R.A.H., R.D.F.), Physiology and Pharmacology (R.G., R.A.H., R.D.F.), and Biochemistry (M.W.H.), Western University, London, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada (P.W.C.); and Department of Public Health and Social Policy, University of Victoria, Victoria, British Columbia, Canada (J.H.B.).

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/ATVBAHA.114.304326
Publisher Site
http://dx.doi.org/10.1161/ATVBAHA.114.304326DOI Listing
January 2015

Gene therapy for hypercholesterolemia: sweet dreams and flying machines.

Circ Res 2014 Aug;115(6):542-5

From the Department of Medicine, Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.114.304800DOI Listing
August 2014

PPARδ activation attenuates hepatic steatosis in Ldlr-/- mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity.

J Lipid Res 2014 07 26;55(7):1254-66. Epub 2014 May 26.

Vascular Biology, Robarts Research Institute, The University of Western Ontario, London, Ontario, Canada, N6A 5B7 Departments of Biochemistry, The University of Western Ontario, London, Ontario, Canada, N6A 5B7 Medicine, The University of Western Ontario, London, Ontario, Canada, N6A 5B7.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M046037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076091PMC
July 2014

Peroxisome proliferator-activated receptor δ agonist GW1516 attenuates diet-induced aortic inflammation, insulin resistance, and atherosclerosis in low-density lipoprotein receptor knockout mice.

Arterioscler Thromb Vasc Biol 2014 Jan 24;34(1):52-60. Epub 2013 Oct 24.

From the Department of Vascular Biology, Robarts Research Institute (L.A.B., A.C.B., S.S.C., D.E.T., B.G.S., J.Y.E., C.G.S., H.Y., J.G.P., M.W.H.), London, Ontario, Canada; and Departments of Biochemistry (L.A.B., A.C.B., S.S.C., J.G.P., M.W.H.), Medicine (D.E.T., J.Y.E., C.G.S., R.G.T., J.G.P., M.W.H.), and Physiology and Pharmacology (R.G.T.), The University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.113.301830DOI Listing
January 2014

Peroxisome proliferator-activated receptor δ: a multifaceted metabolic player.

Curr Opin Lipidol 2013 Apr;24(2):171-7

Department of Biochemistry, Robarts Research Institute, The University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOL.0b013e32835cc949DOI Listing
April 2013

Citrus flavonoids and lipid metabolism.

Curr Opin Lipidol 2013 Feb;24(1):34-40

Department of Biochemistry, Department of Medicine, The University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOL.0b013e32835c07fdDOI Listing
February 2013

The oxysterol 24(s),25-epoxycholesterol attenuates human smooth muscle-derived foam cell formation via reduced low-density lipoprotein uptake and enhanced cholesterol efflux.

J Am Heart Assoc 2012 Jun 22;1(3):e000810. Epub 2012 Jun 22.

Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Canada (M.M.B., C.G.S., J.Y.E., C.O., R.A.H., J.G.P., M.W.H) ; Department of Biochemistry, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Canada (M.M.B., S.R., R.A.H., J.G.P., M.W.H.).

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/JAHA.112.000810
Publisher Site
http://dx.doi.org/10.1161/JAHA.112.000810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487330PMC
June 2012

Citrus flavonoids and the prevention of atherosclerosis.

Cardiovasc Hematol Disord Drug Targets 2012 Dec;12(2):84-91

Vascular Biology, Robarts Research Institute, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1871529x11202020084DOI Listing
December 2012

Activation of peroxisome proliferator-activated receptor δ inhibits human macrophage foam cell formation and the inflammatory response induced by very low-density lipoprotein.

Arterioscler Thromb Vasc Biol 2012 Dec 27;32(12):2919-28. Epub 2012 Sep 27.

Vascular Biology, Robarts Research Institute, Department of Biochemistry, The University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.112.255208DOI Listing
December 2012

Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation.

PPAR Res 2012 30;2012:857142. Epub 2012 May 30.

Vascular Biology Group, Robarts Research Institute, 100 Perth Drive, London, ON, Canada N6A 5K8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2012/857142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369495PMC
August 2012

Canadian global village reality: anthropometric surrogate cutoffs and metabolic abnormalities among Canadians of East Asian, South Asian, and European descent.

Can Fam Physician 2010 May;56(5):e174-82

University of Texas at San Antonio, Department of Health and Kinesiology, One UTSA Circle, San Antonio, TX 78249, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868628PMC
May 2010

Antiatherogenic properties of flavonoids: implications for cardiovascular health.

Can J Cardiol 2010 Mar;26 Suppl A:17A-21A

Vascular Biology, Robarts Research Institute, University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0828-282x(10)71056-4DOI Listing
March 2010

Fibroblast growth factor 21 reduces the severity of cerulein-induced pancreatitis in mice.

Gastroenterology 2009 Nov 5;137(5):1795-804. Epub 2009 Aug 5.

Children's Health Research Institute, London, Ontario.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2009.07.064DOI Listing
November 2009

A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.

Hum Mol Genet 2009 Nov 5;18(21):4189-94. Epub 2009 Aug 5.

Vascular Biology Research Group, Robarts Research Institute and Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddp361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758142PMC
November 2009

Lipid incorporation inhibits Src-dependent assembly of fibronectin and type I collagen by vascular smooth muscle cells.

Circ Res 2009 Apr 19;104(7):832-41. Epub 2009 Feb 19.

Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.108.187302DOI Listing
April 2009

APOA5 genetic variants are markers for classic hyperlipoproteinemia phenotypes and hypertriglyceridemia.

Nat Clin Pract Cardiovasc Med 2008 Nov 9;5(11):730-7. Epub 2008 Sep 9.

Vascular Biology Research Group, Robarts Research Institute and Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON N6A 5K8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncpcardio1326DOI Listing
November 2008

Lipoprotein(a) is associated differentially with carotid stenosis, occlusion, and total plaque area.

Arterioscler Thromb Vasc Biol 2008 Oct 3;28(10):1851-6. Epub 2008 Jul 3.

Schulich School of Medicine and Dentistry, University of Western Ontario, London, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.108.169292DOI Listing
October 2008

Polygenic determinants of severe hypertriglyceridemia.

Hum Mol Genet 2008 Sep 1;17(18):2894-9. Epub 2008 Jul 1.

Vascular Biology Research Group 2 Clinical Trials Group, Robarts Research Institute and Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddn188DOI Listing
September 2008

Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor.

J Lipid Res 2008 Oct 27;49(10):2218-29. Epub 2008 Jun 27.

Robarts Research Institute, Departments of Medicine and Biochemistry, University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M800297-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533411PMC
October 2008

Common variants APOC3, APOA5, APOE and PON1 are associated with variation in plasma lipoprotein traits in Greenlanders.

Int J Circumpolar Health 2007 Dec;66(5):390-400

Vascular Biology Research Group, Robarts Research Institute, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3402/ijch.v66i5.18311DOI Listing
December 2007

Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol.

J Biol Chem 2007 Feb 23;282(8):5207-16. Epub 2006 Dec 23.

Robarts Research Institute Vascular Biology Group, Department of Biochemistry, University of Western, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M611063200DOI Listing
February 2007

The molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin.

J Lipid Res 2007 Mar 27;48(3):699-708. Epub 2006 Nov 27.

Vascular Biology, Robarts Research Institute, The University of Western Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M600439-JLR200DOI Listing
March 2007

Cholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia.

Expert Opin Investig Drugs 2006 Nov;15(11):1337-51

Royal Perth Hospital, Department of Core Clinical Pathology & Biochemistry, PathWest Laboratory Medicine WA, Wellington Street Campus, GPO Box X2213, Perth, WA 6847, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/13543784.15.11.1337DOI Listing
November 2006

Ankyrin G overexpression in Hutchinson-Gilford progeria syndrome fibroblasts identified through biological filtering of expression profiles.

J Hum Genet 2006 11;51(11):934-942. Epub 2006 Oct 11.

Vascular Biology Research Group, Robarts Research Institute, 406-100 Perth Drive, London, ON, Canada, N6A 5K8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10038-006-0042-0DOI Listing
January 2007

NPC1L1: evolution from pharmacological target to physiological sterol transporter.

Arterioscler Thromb Vasc Biol 2006 Nov 14;26(11):2433-8. Epub 2006 Sep 14.

Vascular Biology Group, Robarts Research Institute, London, Ontario, Canada.

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/01.ATV.0000245791.53
Publisher Site
http://dx.doi.org/10.1161/01.ATV.0000245791.53245.eeDOI Listing
November 2006

The ACAT inhibitor avasimibe increases the fractional clearance rate of postprandial triglyceride-rich lipoproteins in miniature pigs.

Biochim Biophys Acta 2005 Dec 22;1738(1-3):10-8. Epub 2005 Dec 22.

Department of Core Clinical Pathology and Biochemistry, Pathwest Laboratory Medicine WA, Royal Perth Hospital and School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2005.11.010DOI Listing
December 2005

Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear.

Trends Pharmacol Sci 2005 Jul;26(7):335-40

Robarts Research Institute, Vascular Biology Group, Departments of Medicine and Biochemistry, The University of Western Ontario, London, Ontario N6A 5K8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tips.2005.05.004DOI Listing
July 2005

Quality assessment of microarray experiments.

Clin Biochem 2005 Jul;38(7):639-42

London Regional Genomics Centre, Robarts Research Institute, London, Ontario, Canada N6A 5K8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinbiochem.2005.04.010DOI Listing
July 2005

Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux.

J Biol Chem 2005 Jun 6;280(23):22212-21. Epub 2005 Apr 6.

Robarts Research Institute, Vascular Biology Group, and the Departments of Medicine and Biochemistry, the University of Western Ontario, London, Ontario N6A 5K8, Canada.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M502761200
Publisher Site
http://dx.doi.org/10.1074/jbc.M502761200DOI Listing
June 2005

Human smooth muscle cell subpopulations differentially accumulate cholesteryl ester when exposed to native and oxidized lipoproteins.

Arterioscler Thromb Vasc Biol 2004 Jul 6;24(7):1290-6. Epub 2004 May 6.

Vascular Biology Group at the Robarts Research Institute, University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/01.ATV.0000131260.80
Publisher Site
http://dx.doi.org/10.1161/01.ATV.0000131260.80316.37DOI Listing
July 2004

Dietary cholesterol, cholesterol absorption, postprandial lipemia and atherosclerosis.

Authors:
Murray W Huff

Can J Clin Pharmacol 2003 ;10 Suppl A:26A-32A

Vascular Biology Group, Robarts Research Institute, University of Western Ontario, London.

View Article

Download full-text PDF

Source
December 2003

Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation.

Diabetes 2003 Oct;52(10):2554-61

Department of Medicine and the Robarts Research Institute, University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/diabetes.52.10.2554DOI Listing
October 2003

Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation.

Circ Res 2003 Oct 25;93(8):717-25. Epub 2003 Sep 25.

Robarts Research Institute, Vascular Biology Group, University of Western Ontario, 100 Perth Dr, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.RES.0000097606.43659.F4DOI Listing
October 2003

Inhibition of both the apical sodium-dependent bile acid transporter and HMG-CoA reductase markedly enhances the clearance of LDL apoB.

J Lipid Res 2003 May 1;44(5):943-52. Epub 2003 Feb 1.

Robarts Research Institute and Departments of Medicine and Biochemistry, University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M200482-JLR200DOI Listing
May 2003

Elevated serum C-reactive protein and free fatty acids among nondiabetic carriers of missense mutations in the gene encoding lamin A/C (LMNA) with partial lipodystrophy.

Arterioscler Thromb Vasc Biol 2003 Jan;23(1):111-6

Blackburn Cardiovascular Genetics Laboratory and Vascular Biology Research Group, Robarts Research Institute, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.atv.0000047460.27435.b8DOI Listing
January 2003

Avasimibe Pfizer.

Curr Opin Investig Drugs 2002 Sep;3(9):1328-33

Department of Core Clinical Pathology & Biochemistry, Division of Laboratory Medicine, Royal Perth Hospital, Wellington Street, Perth, WA 6847, Australia.

View Article

Download full-text PDF

Source
September 2002

Inhibition of the apical sodium-dependent bile acid transporter reduces LDL cholesterol and apoB by enhanced plasma clearance of LDL apoB.

Arterioscler Thromb Vasc Biol 2002 Nov;22(11):1884-91

Department of Medicine and Biochemistry and The John P. Robarts Research Institute, The University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.atv.0000035390.87288.26DOI Listing
November 2002

Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters.

J Lipid Res 2002 Sep;43(9):1544-54

Department of Medicine and Biochemistry, John P. Robarts Research Institute, University of Western Ontario, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.m200115-jlr200DOI Listing
September 2002