Murray J Cairns

Murray J Cairns

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Murray J Cairns

Murray J Cairns

Publications by authors named "Murray J Cairns"

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The maternal immune activation model uncovers a role for the Arx gene in GABAergic dysfunction in schizophrenia.

Brain Behav Immun 2019 Jun 5. Epub 2019 Jun 5.

Florey Institute for Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3010, Australia; Department of Psychiatry, School of Clinical Sciences, Monash University, Clayton, Victoria 3168, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2019.06.009DOI Listing
June 2019

Circular RNA biogenesis is decreased in postmortem cortical gray matter in schizophrenia and may alter the bioavailability of associated miRNA.

Neuropsychopharmacology 2019 05 20;44(6):1043-1054. Epub 2019 Feb 20.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, 2308, Australia.

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http://dx.doi.org/10.1038/s41386-019-0348-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461776PMC
May 2019

Alteration of miRNA-mRNA interactions in lymphocytes of individuals with schizophrenia.

J Psychiatr Res 2019 May 5;112:89-98. Epub 2019 Mar 5.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, New South Wales, Australia; Centre for Brain and Mental Health Research, Hunter Medical Research Institute, New Lambton, New South Wales, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2019.02.023DOI Listing
May 2019

Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?

Authors:
Theo G M van Erp Esther Walton Derrek P Hibar Lianne Schmaal Wenhao Jiang David C Glahn Godfrey D Pearlson Nailin Yao Masaki Fukunaga Ryota Hashimoto Naohiro Okada Hidenaga Yamamori Vincent P Clark Bryon A Mueller Sonja M C de Zwarte Roel A Ophoff Neeltje E M van Haren Ole A Andreassen Tiril P Gurholt Oliver Gruber Bernd Kraemer Anja Richter Vince D Calhoun Benedicto Crespo-Facorro Roberto Roiz-Santiañez Diana Tordesillas-Gutiérrez Carmel Loughland Stanley Catts Janice M Fullerton Melissa J Green Frans Henskens Assen Jablensky Bryan J Mowry Christos Pantelis Yann Quidé Ulrich Schall Rodney J Scott Murray J Cairns Marc Seal Paul A Tooney Paul E Rasser Gavin Cooper Cynthia Shannon Weickert Thomas W Weickert Elliot Hong Peter Kochunov Raquel E Gur Ruben C Gur Judith M Ford Fabio Macciardi Daniel H Mathalon Steven G Potkin Adrian Preda Fengmei Fan Stefan Ehrlich Margaret D King Lieuwe De Haan Dick J Veltman Francesca Assogna Nerisa Banaj Pietro de Rossi Mariangela Iorio Fabrizio Piras Gianfranco Spalletta Edith Pomarol-Clotet Sinead Kelly Simone Ciufolini Joaquim Radua Robin Murray Tiago Reis Marques Andrew Simmons Stefan Borgwardt Fabienne Schönborn-Harrisberger Anita Riecher-Rössler Renata Smieskova Kathryn I Alpert Alessandro Bertolino Aurora Bonvino Annabella Di Giorgio Emma Neilson Andrew R Mayer Je-Yeon Yun Dara M Cannon Irina Lebedeva Alexander S Tomyshev Tolibjohn Akhadov Vasily Kaleda Helena Fatouros-Bergman Lena Flyckt Pedro G P Rosa Mauricio H Serpa Marcus V Zanetti Cyril Hoschl Antonin Skoch Filip Spaniel David Tomecek Andrew M McIntosh Heather C Whalley Christian Knöchel Viola Oertel-Knöchel Fleur M Howells Dan J Stein Henk S Temmingh Anne Uhlmann Carlos Lopez-Jaramillo Danai Dima Joshua I Faskowitz Boris A Gutman Neda Jahanshad Paul M Thompson Jessica A Turner

Biol Psychiatry 2019 04 22;85(7):e35-e39. Epub 2018 Nov 22.

Imaging Genetics and Neuroinformatics Laboratory, Department of Psychology, Georgia State University, Atlanta, Georgia; Mind Research Network, Albuquerque, New Mexico.

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http://dx.doi.org/10.1016/j.biopsych.2018.10.003DOI Listing
April 2019

Small RNA regulators of social behaviour in eutherian mammals.

Authors:
Murray J Cairns

EMBO Rep 2019 Feb 23;20(2). Epub 2019 Jan 23.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.15252/embr.201947663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362344PMC
February 2019

Temporospatial guidance of activity-dependent gene expression by microRNA: mechanisms and functional implications for neural plasticity.

Nucleic Acids Res 2019 01;47(2):533-545

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, 2323, Australia.

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http://dx.doi.org/10.1093/nar/gky1235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344879PMC
January 2019

Polygenic disruption of retinoid signalling in schizophrenia and a severe cognitive deficit subtype.

Mol Psychiatry 2018 Dec 7. Epub 2018 Dec 7.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.1038/s41380-018-0305-0DOI Listing
December 2018

Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium.

Authors:
Theo G M van Erp Esther Walton Derrek P Hibar Lianne Schmaal Wenhao Jiang David C Glahn Godfrey D Pearlson Nailin Yao Masaki Fukunaga Ryota Hashimoto Naohiro Okada Hidenaga Yamamori Juan R Bustillo Vincent P Clark Ingrid Agartz Bryon A Mueller Wiepke Cahn Sonja M C de Zwarte Hilleke E Hulshoff Pol René S Kahn Roel A Ophoff Neeltje E M van Haren Ole A Andreassen Anders M Dale Nhat Trung Doan Tiril P Gurholt Cecilie B Hartberg Unn K Haukvik Kjetil N Jørgensen Trine V Lagerberg Ingrid Melle Lars T Westlye Oliver Gruber Bernd Kraemer Anja Richter David Zilles Vince D Calhoun Benedicto Crespo-Facorro Roberto Roiz-Santiañez Diana Tordesillas-Gutiérrez Carmel Loughland Vaughan J Carr Stanley Catts Vanessa L Cropley Janice M Fullerton Melissa J Green Frans A Henskens Assen Jablensky Rhoshel K Lenroot Bryan J Mowry Patricia T Michie Christos Pantelis Yann Quidé Ulrich Schall Rodney J Scott Murray J Cairns Marc Seal Paul A Tooney Paul E Rasser Gavin Cooper Cynthia Shannon Weickert Thomas W Weickert Derek W Morris Elliot Hong Peter Kochunov Lauren M Beard Raquel E Gur Ruben C Gur Theodore D Satterthwaite Daniel H Wolf Aysenil Belger Gregory G Brown Judith M Ford Fabio Macciardi Daniel H Mathalon Daniel S O'Leary Steven G Potkin Adrian Preda James Voyvodic Kelvin O Lim Sarah McEwen Fude Yang Yunlong Tan Shuping Tan Zhiren Wang Fengmei Fan Jingxu Chen Hong Xiang Shiyou Tang Hua Guo Ping Wan Dong Wei Henry J Bockholt Stefan Ehrlich Rick P F Wolthusen Margaret D King Jody M Shoemaker Scott R Sponheim Lieuwe De Haan Laura Koenders Marise W Machielsen Therese van Amelsvoort Dick J Veltman Francesca Assogna Nerisa Banaj Pietro de Rossi Mariangela Iorio Fabrizio Piras Gianfranco Spalletta Peter J McKenna Edith Pomarol-Clotet Raymond Salvador Aiden Corvin Gary Donohoe Sinead Kelly Christopher D Whelan Erin W Dickie David Rotenberg Aristotle N Voineskos Simone Ciufolini Joaquim Radua Paola Dazzan Robin Murray Tiago Reis Marques Andrew Simmons Stefan Borgwardt Laura Egloff Fabienne Harrisberger Anita Riecher-Rössler Renata Smieskova Kathryn I Alpert Lei Wang Erik G Jönsson Sanne Koops Iris E C Sommer Alessandro Bertolino Aurora Bonvino Annabella Di Giorgio Emma Neilson Andrew R Mayer Julia M Stephen Jun Soo Kwon Je-Yeon Yun Dara M Cannon Colm McDonald Irina Lebedeva Alexander S Tomyshev Tolibjohn Akhadov Vasily Kaleda Helena Fatouros-Bergman Lena Flyckt Geraldo F Busatto Pedro G P Rosa Mauricio H Serpa Marcus V Zanetti Cyril Hoschl Antonin Skoch Filip Spaniel David Tomecek Saskia P Hagenaars Andrew M McIntosh Heather C Whalley Stephen M Lawrie Christian Knöchel Viola Oertel-Knöchel Michael Stäblein Fleur M Howells Dan J Stein Henk S Temmingh Anne Uhlmann Carlos Lopez-Jaramillo Danai Dima Agnes McMahon Joshua I Faskowitz Boris A Gutman Neda Jahanshad Paul M Thompson Jessica A Turner

Biol Psychiatry 2018 11 14;84(9):644-654. Epub 2018 May 14.

Imaging Genetics and Neuroinformatics Lab, Georgia State University, Atlanta, Georgia; Mind Research Network, Albuquerque, New Mexico.

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http://dx.doi.org/10.1016/j.biopsych.2018.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177304PMC
November 2018

Temporally specific miRNA expression patterns in the dorsal and ventral striatum of addiction-prone rats.

Addict Biol 2018 03 13;23(2):631-642. Epub 2017 Jun 13.

Neurobiology of Addiction Laboratory, School of Biomedical Sciences and Pharmacy and the Centre for Translational Neuroscience and Mental Health Research, University of Newcastle and the Hunter Medical Research Institute, Australia.

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http://dx.doi.org/10.1111/adb.12520DOI Listing
March 2018

Common variation in ZNF804A (rs1344706) is not associated with brain morphometry in schizophrenia or healthy participants.

Prog Neuropsychopharmacol Biol Psychiatry 2018 03 13;82:12-20. Epub 2017 Dec 13.

School of Psychiatry, University of New South Wales (UNSW), Randwick, NSW, Australia; Neuroscience Research Australia, Randwick, NSW, Australia; ARC Centre for Cognition and its Disorders (CCD), Macquarie University, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2017.12.007DOI Listing
March 2018

Inhibition of extracellular matrix mediated TGF-β signalling suppresses endometrial cancer metastasis.

Oncotarget 2017 Sep 22;8(42):71400-71417. Epub 2017 May 22.

Gynaecology Oncology Group, School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia.

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http://dx.doi.org/10.18632/oncotarget.18069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641058PMC
September 2017

miRNA Enriched in Human Neuroblast Nuclei Bind the MAZ Transcription Factor and Their Precursors Contain the MAZ Consensus Motif.

Front Mol Neurosci 2017 21;10:259. Epub 2017 Aug 21.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, CallaghanNSW, Australia.

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http://dx.doi.org/10.3389/fnmol.2017.00259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573442PMC
August 2017

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Authors:
Christian R Marshall Daniel P Howrigan Daniele Merico Bhooma Thiruvahindrapuram Wenting Wu Douglas S Greer Danny Antaki Aniket Shetty Peter A Holmans Dalila Pinto Madhusudan Gujral William M Brandler Dheeraj Malhotra Zhouzhi Wang Karin V Fuentes Fajarado Michelle S Maile Stephan Ripke Ingrid Agartz Margot Albus Madeline Alexander Farooq Amin Joshua Atkins Silviu A Bacanu Richard A Belliveau Sarah E Bergen Marcelo Bertalan Elizabeth Bevilacqua Tim B Bigdeli Donald W Black Richard Bruggeman Nancy G Buccola Randy L Buckner Brendan Bulik-Sullivan William Byerley Wiepke Cahn Guiqing Cai Murray J Cairns Dominique Campion Rita M Cantor Vaughan J Carr Noa Carrera Stanley V Catts Kimberley D Chambert Wei Cheng C Robert Cloninger David Cohen Paul Cormican Nick Craddock Benedicto Crespo-Facorro James J Crowley David Curtis Michael Davidson Kenneth L Davis Franziska Degenhardt Jurgen Del Favero Lynn E DeLisi Dimitris Dikeos Timothy Dinan Srdjan Djurovic Gary Donohoe Elodie Drapeau Jubao Duan Frank Dudbridge Peter Eichhammer Johan Eriksson Valentina Escott-Price Laurent Essioux Ayman H Fanous Kai-How Farh Martilias S Farrell Josef Frank Lude Franke Robert Freedman Nelson B Freimer Joseph I Friedman Andreas J Forstner Menachem Fromer Giulio Genovese Lyudmila Georgieva Elliot S Gershon Ina Giegling Paola Giusti-Rodríguez Stephanie Godard Jacqueline I Goldstein Jacob Gratten Lieuwe de Haan Marian L Hamshere Mark Hansen Thomas Hansen Vahram Haroutunian Annette M Hartmann Frans A Henskens Stefan Herms Joel N Hirschhorn Per Hoffmann Andrea Hofman Hailiang Huang Masashi Ikeda Inge Joa Anna K Kähler René S Kahn Luba Kalaydjieva Juha Karjalainen David Kavanagh Matthew C Keller Brian J Kelly James L Kennedy Yunjung Kim James A Knowles Bettina Konte Claudine Laurent Phil Lee S Hong Lee Sophie E Legge Bernard Lerer Deborah L Levy Kung-Yee Liang Jeffrey Lieberman Jouko Lönnqvist Carmel M Loughland Patrik K E Magnusson Brion S Maher Wolfgang Maier Jacques Mallet Manuel Mattheisen Morten Mattingsdal Robert W McCarley Colm McDonald Andrew M McIntosh Sandra Meier Carin J Meijer Ingrid Melle Raquelle I Mesholam-Gately Andres Metspalu Patricia T Michie Lili Milani Vihra Milanova Younes Mokrab Derek W Morris Bertram Müller-Myhsok Kieran C Murphy Robin M Murray Inez Myin-Germeys Igor Nenadic Deborah A Nertney Gerald Nestadt Kristin K Nicodemus Laura Nisenbaum Annelie Nordin Eadbhard O'Callaghan Colm O'Dushlaine Sang-Yun Oh Ann Olincy Line Olsen F Anthony O'Neill Jim Van Os Christos Pantelis George N Papadimitriou Elena Parkhomenko Michele T Pato Tiina Paunio Diana O Perkins Tune H Pers Olli Pietiläinen Jonathan Pimm Andrew J Pocklington John Powell Alkes Price Ann E Pulver Shaun M Purcell Digby Quested Henrik B Rasmussen Abraham Reichenberg Mark A Reimers Alexander L Richards Joshua L Roffman Panos Roussos Douglas M Ruderfer Veikko Salomaa Alan R Sanders Adam Savitz Ulrich Schall Thomas G Schulze Sibylle G Schwab Edward M Scolnick Rodney J Scott Larry J Seidman Jianxin Shi Jeremy M Silverman Jordan W Smoller Erik Söderman Chris C A Spencer Eli A Stahl Eric Strengman Jana Strohmaier T Scott Stroup Jaana Suvisaari Dragan M Svrakic Jin P Szatkiewicz Srinivas Thirumalai Paul A Tooney Juha Veijola Peter M Visscher John Waddington Dermot Walsh Bradley T Webb Mark Weiser Dieter B Wildenauer Nigel M Williams Stephanie Williams Stephanie H Witt Aaron R Wolen Brandon K Wormley Naomi R Wray Jing Qin Wu Clement C Zai Rolf Adolfsson Ole A Andreassen Douglas H R Blackwood Elvira Bramon Joseph D Buxbaum Sven Cichon David A Collier Aiden Corvin Mark J Daly Ariel Darvasi Enrico Domenici Tõnu Esko Pablo V Gejman Michael Gill Hugh Gurling Christina M Hultman Nakao Iwata Assen V Jablensky Erik G Jönsson Kenneth S Kendler George Kirov Jo Knight Douglas F Levinson Qingqin S Li Steven A McCarroll Andrew McQuillin Jennifer L Moran Bryan J Mowry Markus M Nöthen Roel A Ophoff Michael J Owen Aarno Palotie Carlos N Pato Tracey L Petryshen Danielle Posthuma Marcella Rietschel Brien P Riley Dan Rujescu Pamela Sklar David St Clair James T R Walters Thomas Werge Patrick F Sullivan Michael C O'Donovan Stephen W Scherer Benjamin M Neale Jonathan Sebat

Nat Genet 2017 01 21;49(1):27-35. Epub 2016 Nov 21.

Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/ng.3725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737772PMC
January 2017

Noncoding RNA Regulation of Dopamine Signaling in Diseases of the Central Nervous System.

Front Mol Biosci 2016 25;3:69. Epub 2016 Oct 25.

Department of Chemistry, Georgia Southern University Statesboro, GA, USA.

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http://dx.doi.org/10.3389/fmolb.2016.00069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078498PMC
October 2016

Alteration of transcriptional networks in the entorhinal cortex after maternal immune activation and adolescent cannabinoid exposure.

Brain Behav Immun 2016 Aug 26;56:187-96. Epub 2016 Feb 26.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW, Australia; Schizophrenia Research Institute, Sydney, NSW, Australia; Centre for Brain and Mental Health Research, Hunter Medical Research Institute, Newcastle, NSW 2305, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2016.02.021DOI Listing
August 2016

MicroRNA: Small RNA mediators of the brains genomic response to environmental stress.

Prog Neurobiol 2016 08 15;143:61-81. Epub 2016 Jun 15.

School of Biomedical Sciences and Pharmacy and the Hunter Medical Research Institute, the University of Newcastle, Callaghan, NSW 2308, Australia; Schizophrenia Research Institute, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2016.06.005DOI Listing
August 2016

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women.

JAMA Psychiatry 2016 05;73(5):497-505

Schizophrenia Research Institute, Sydney, Australia23School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia.

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http://dx.doi.org/10.1001/jamapsychiatry.2016.0129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785705PMC
May 2016

Altered neural signaling and immune pathways in peripheral blood mononuclear cells of schizophrenia patients with cognitive impairment: A transcriptome analysis.

Brain Behav Immun 2016 Mar 14;53:194-206. Epub 2015 Dec 14.

School of Biomedical Sciences and Pharmacy, Faculty of Health, The University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; Schizophrenia Research Institute, Sydney, Australia; Centre for Translational Neuroscience and Mental Health, Hunter Medical Research Institute, Newcastle, NSW 2305, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2015.12.010DOI Listing
March 2016

Do common genotypes of FK506 binding protein 5 (FKBP5) moderate the effects of childhood maltreatment on cognition in schizophrenia and healthy controls?

J Psychiatr Res 2015 Nov 18;70:9-17. Epub 2015 Jul 18.

School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia; Schizophrenia Research Institute, Darlinghurst, NSW, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S00223956150021
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http://dx.doi.org/10.1016/j.jpsychires.2015.07.019DOI Listing
November 2015

The effect of a muscarinic receptor 1 gene variant on grey matter volume in schizophrenia.

Psychiatry Res 2015 Nov 10;234(2):182-7. Epub 2015 Sep 10.

Department of Psychiatry, The University of Melbourne, Parkville, Victoria 3052, Australia; Molecular Psychiatry Laboratory, Florey Institute of Neuroscience and Mental Health, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1016/j.pscychresns.2015.09.004DOI Listing
November 2015

Circulating miRNA biomarkers for schizophrenia?

Authors:
Murray J Cairns

Am J Psychiatry 2015 Nov;172(11):1059-61

From the School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Callaghan, Australia; the Schizophrenia Research Institute, Sydney; and the Priority Research Centre for Translational Neuroscience and Mental Health, Hunter Medical Research Institute, New Lambton.

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http://dx.doi.org/10.1176/appi.ajp.2015.15081060DOI Listing
November 2015

CX3CR1 is dysregulated in blood and brain from schizophrenia patients.

Schizophr Res 2015 10 15;168(1-2):434-43. Epub 2015 Aug 15.

Aix Marseille Université, CNRS, CRN2M UMR 7286, 13344 Marseille Cedex 15, France; FondaMental, Fondation de Recherche et de Soins en Santé Mentale, 94000 Créteil, France. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.08.010DOI Listing
October 2015

Proteotranscriptomic Profiling of 231-BR Breast Cancer Cells: Identification of Potential Biomarkers and Therapeutic Targets for Brain Metastasis.

Mol Cell Proteomics 2015 Sep 3;14(9):2316-30. Epub 2015 Jun 3.

From the ‡School of Biomedical Sciences & Pharmacy and §Hunter Medical Research Institute, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales 2308, Australia

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http://dx.doi.org/10.1074/mcp.M114.046110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563718PMC
September 2015

MicroRNA and Posttranscriptional Dysregulation in Psychiatry.

Biol Psychiatry 2015 Aug 18;78(4):231-9. Epub 2014 Dec 18.

School of Biomedical Sciences, Faculty of Health and Medicine, University of Newcastle, Callaghan, Australia.; Schizophrenia Research Institute, Sydney, Australia.; Centre for Translational Neuroscience and Mental Health, Hunter Medical Research Institute, Newcastle, New South Wales, Australia.. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2014.12.009DOI Listing
August 2015

Multivariate neuroanatomical classification of cognitive subtypes in schizophrenia: a support vector machine learning approach.

Neuroimage Clin 2014 18;6:229-36. Epub 2014 Sep 18.

Schizophrenia Research Institute, Darlinghurst, NSW, Australia ; School of Psychiatry, University of New South Wales, Australia ; Black Dog Institute, Prince of Wales Hospital, Randwick, NSW, Australia ; Neuroscience Research Australia, Randwick, NSW, Australia.

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http://dx.doi.org/10.1016/j.nicl.2014.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215428PMC
July 2015

Understanding complex transcriptome dynamics in schizophrenia and other neurological diseases using RNA sequencing.

Int Rev Neurobiol 2014 ;116:127-52

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales, Australia; The Schizophrenia Research Institute, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-801105-8.00006-0DOI Listing
May 2015

Optimal consistency in microRNA expression analysis using reference-gene-based normalization.

Mol Biosyst 2015 May;11(5):1235-40

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, NSW 2308, Australia.

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http://dx.doi.org/10.1039/c4mb00711eDOI Listing
May 2015

Chemosensitization of solid tumors by inhibition of Bcl-xL expression using DNAzyme.

Oncotarget 2014 Oct;5(19):9039-48

Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253417PMC
http://dx.doi.org/10.18632/oncotarget.1996DOI Listing
October 2014

BDNF and the maturation of posttranscriptional regulatory networks in human SH-SY5Y neuroblast differentiation.

Front Cell Neurosci 2014 15;8:325. Epub 2014 Oct 15.

The Centre for Translational Neuroscience and Mental Health, School of Biomedical Sciences and Pharmacy, University of Newcastle Callaghan, NSW, Australia ; Schizophrenia Research Institute Sydney, NSW, Australia.

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http://dx.doi.org/10.3389/fncel.2014.00325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197648PMC
October 2014

Ontogeny of small RNA in the regulation of mammalian brain development.

BMC Genomics 2014 Sep 9;15:777. Epub 2014 Sep 9.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, the University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.

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http://dx.doi.org/10.1186/1471-2164-15-777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171549PMC
September 2014

Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons.

Nucleic Acids Res 2014 Aug 22;42(14):9195-208. Epub 2014 Jul 22.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia Schizophrenia Research Institute, Sydney, Australia Centre for Translational Neuroscience and Mental Health, Hunter Medical Research Institute, University of Newcastle, Callaghan, NSW 2308, Australia

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http://dx.doi.org/10.1093/nar/gku594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132720PMC
August 2014

Antipsychotic drug-associated gene-miRNA interaction in T-lymphocytes.

Int J Neuropsychopharmacol 2014 Jun 30;17(6):929-43. Epub 2014 Jan 30.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, NSW, Australia.

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http://dx.doi.org/10.1017/S1461145713001752DOI Listing
June 2014

SeqGSEA: a Bioconductor package for gene set enrichment analysis of RNA-Seq data integrating differential expression and splicing.

Bioinformatics 2014 Jun 17;30(12):1777-9. Epub 2014 Feb 17.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Newcastle, Hunter Medical Research Institute, New Lambton, and Schizophrenia Research Institute, Sydney, NSW, AustraliaSchool of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Newcastle, Hunter Medical Research Institute, New Lambton, and Schizophrenia Research Institute, Sydney, NSW, AustraliaSchool of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Newcastle, Hunter Medical Research Institute, New Lambton, and Schizophrenia Research Institute, Sydney, NSW, Australia.

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http://dx.doi.org/10.1093/bioinformatics/btu090DOI Listing
June 2014

Combined analysis of exon splicing and genome wide polymorphism data predict schizophrenia risk loci.

J Psychiatr Res 2014 May 24;52:44-9. Epub 2014 Jan 24.

Hunter Medical Research Institute and Faculty of Health, University of Newcastle, NSW, Australia; School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, NSW, Australia; Division of Molecular Medicine, Hunter Area Pathology Service, John Hunter Hospital, Newcastle, NSW, Australia.

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http://dx.doi.org/10.1016/j.jpsychires.2014.01.011DOI Listing
May 2014

Regulation of gene expression by microRNA in HCV infection and HCV-mediated hepatocellular carcinoma.

Virol J 2014 Apr 1;11:64. Epub 2014 Apr 1.

Centre for Virus Research, Westmead Millennium Institute, Darcy Road, Sydney, Westmead NSW 2145, Australia.

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http://dx.doi.org/10.1186/1743-422X-11-64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977900PMC
April 2014

Maturation of the human dorsolateral prefrontal cortex coincides with a dynamic shift in microRNA expression.

Schizophr Bull 2014 Mar 31;40(2):399-409. Epub 2013 Jan 31.

To whom correspondence should be addressed; School of Biomedical Sciences & Pharmacy, The University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; tel: +61-2-4921-8670, fax: +61-2-4921-7903, e-mail:

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http://dx.doi.org/10.1093/schbul/sbs198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932079PMC
March 2014

Preliminary evidence of an interaction between the FOXP2 gene and childhood emotional abuse predicting likelihood of auditory verbal hallucinations in schizophrenia.

J Psychiatr Res 2014 Mar 7;50:66-72. Epub 2013 Dec 7.

School of Psychiatry, Faculty of Medicine, University of New South Wales, NSW, Australia; Schizophrenia Research Institute, Sydney, NSW, Australia.

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March 2014

Catechol-O-methyltransferase (COMT) genotype moderates the effects of childhood trauma on cognition and symptoms in schizophrenia.

J Psychiatr Res 2014 Feb 8;49:43-50. Epub 2013 Nov 8.

School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia; Schizophrenia Research Institute, Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.1016/j.jpsychires.2013.10.018DOI Listing
February 2014

Identifying miRNAs, targets and functions.

Brief Bioinform 2014 Jan 22;15(1):1-19. Epub 2012 Nov 22.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, University Drive, Callaghan NSW 2308, Australia.

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http://dx.doi.org/10.1093/bib/bbs075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896928PMC
January 2014

Gene set enrichment analysis of RNA-Seq data: integrating differential expression and splicing.

BMC Bioinformatics 2013 10;14 Suppl 5:S16. Epub 2013 Apr 10.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, New South Wales, Australia.

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http://dx.doi.org/10.1186/1471-2105-14-S5-S16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622641PMC
December 2013

Discovering functional microRNA-mRNA regulatory modules in heterogeneous data.

Adv Exp Med Biol 2013 ;774:267-90

University of New South Wales, Randwick, NSW, Australia.

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http://dx.doi.org/10.1007/978-94-007-5590-1_14DOI Listing
June 2013

Design and interpretation of microRNA-reporter gene activity.

Anal Biochem 2013 Jun 7;437(2):164-71. Epub 2013 Mar 7.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Hunter Medical Research Institute, University of Newcastle, Callaghan, NSW 2308, Australia.

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June 2013

Gene-microRNA interactions associated with antipsychotic mechanisms and the metabolic side effects of olanzapine.

Psychopharmacology (Berl) 2013 May 15;227(1):67-78. Epub 2013 Jan 15.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, University Drive, Callaghan, NSW, 2308, Australia.

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http://dx.doi.org/10.1007/s00213-012-2939-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622003PMC
May 2013

Context-specific microRNA function in developmental complexity.

J Mol Cell Biol 2013 Apr 28;5(2):73-84. Epub 2013 Jan 28.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Hunter Medical Research Institute, University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.1093/jmcb/mjt004DOI Listing
April 2013

MicroRNA-16 is down-regulated in mutated FLT3 expressing murine myeloid FDC-P1 cells and interacts with Pim-1.

PLoS One 2012 6;7(9):e44546. Epub 2012 Sep 6.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435263PMC
March 2013

Advances in non-coding RNA profiling for neurological diseases.

Front Genet 2013 25;4. Epub 2013 Jan 25.

School of Biomedical Sciences and Pharmacy, and Hunter Medical Research Institute, University of Newcastle Callaghan, NSW, Australia ; Schizophrenia Research Institute Sydney, NSW, Australia.

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http://dx.doi.org/10.3389/fgene.2013.00005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554880PMC
January 2013

Alternative mRNA fates identified in microRNA-associated transcriptome analysis.

BMC Genomics 2012 Oct 19;13:561. Epub 2012 Oct 19.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Hunter Medical Research Institute, University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.1186/1471-2164-13-561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505728PMC
October 2012

MicroRNA dysregulation in schizophrenia.

Neurobiol Dis 2012 May 21;46(2):263-71. Epub 2011 Dec 21.

Faculty of Health and the Hunter Medical Research Institute, School of Biomedical Sciences and Pharmacy, The University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.

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http://dx.doi.org/10.1016/j.nbd.2011.12.029DOI Listing
May 2012

A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia.

Brain Behav Immun 2012 Mar 11;26(3):469-79. Epub 2012 Jan 11.

School of Biomedical Sciences & Pharmacy, The University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.

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March 2012

Post-transcriptional trafficking and regulation of neuronal gene expression.

Mol Neurobiol 2012 Feb 14;45(1):99-108. Epub 2011 Dec 14.

School of Biomedical Sciences and Pharmacy, Faculty of Health and the Hunter Medical Research Institute, The University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259350PMC
February 2012

Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia.

Biol Psychiatry 2011 Jan 15;69(2):180-7. Epub 2010 Dec 15.

Schizophrenia Research Institute, Sydney, Australia.

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http://dx.doi.org/10.1016/j.biopsych.2010.09.030DOI Listing
January 2011

Substituted 9-aminoacridine-4-carboxamides tethered to platinum(II)diamine complexes: chemistry, cytotoxicity and DNA sequence selectivity.

J Inorg Biochem 2010 Aug 27;104(8):815-9. Epub 2010 Mar 27.

School of Chemistry, The University of Melbourne, Grattan Street, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1016/j.jinorgbio.2010.03.011DOI Listing
August 2010

Recent patents in antiviral siRNAs.

Recent Pat Antiinfect Drug Discov 2010 Jan;5(1):44-57

School of Biomedical Science, Faculty of Health, and Hunter Medical Research Institute, The University of Newcastle, University Drive, Callagham, NSW 2308, Australia.

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January 2010

Broad-spectrum and virus-specific nucleic acid-based antivirals against influenza.

Front Biosci (Schol Ed) 2010 Jan 1;2:791-800. Epub 2010 Jan 1.

Molecular Biology Group, Biotechnology Section, Defence Research and Development Canada - Suffield, Ralston, Alberta, Canada.

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January 2010

Down-regulation of miR-17 family expression in response to retinoic acid induced neuronal differentiation.

Cell Signal 2009 Dec 8;21(12):1837-45. Epub 2009 Aug 8.

Schizophrenia Research Institute, Sydney, NSW 2006, Australia.

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December 2009

The DNA sequence selectivity of maltolato-containing cisplatin analogues in purified plasmid DNA and in intact human cells.

J Inorg Biochem 2009 Aug 13;103(8):1151-5. Epub 2009 Jun 13.

University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1016/j.jinorgbio.2009.06.001DOI Listing
August 2009

Primer fabrication using polymerase mediated oligonucleotide synthesis.

BMC Genomics 2009 Jul 31;10:344. Epub 2009 Jul 31.

Schizophrenia Research Institute, Sydney, NSW 2006, Australia.

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http://dx.doi.org/10.1186/1471-2164-10-344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733156PMC
July 2009

RNA modulators of complex phenotypes in mammalian cells.

PLoS One 2009 9;4(3):e4758. Epub 2009 Mar 9.

Johnson and Johnson Research Pty Ltd, Australian Technology Park, Eveleigh, New South Wales, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650256PMC
May 2009

Dysregulation of miRNA 181b in the temporal cortex in schizophrenia.

Hum Mol Genet 2008 Apr 9;17(8):1156-68. Epub 2008 Jan 9.

Schizophrenia Research Institute, Sydney, NSW 2006, Australia.

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http://dx.doi.org/10.1093/hmg/ddn005DOI Listing
April 2008

Target-site selection for the 10-23 DNAzyme.

Methods Mol Biol 2004 ;252:267-77

Johnson & Johnson Research Laboratories, Australian Technology Park, Eveleigh.

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http://dx.doi.org/10.1385/1-59259-746-7:267DOI Listing
June 2004

Nucleic acid sequence analysis using DNAzymes.

Methods Mol Biol 2004 ;252:291-302

Johnson and Johnson Research Laboratories, Australian Technology Park, Eveleigh.

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June 2004

Homogeneous real-time detection and quantification of nucleic acid amplification using restriction enzyme digestion.

Biochem Biophys Res Commun 2004 Jun;318(3):684-90

Johnson and Johnson Research Laboratories, Level 4/One Central Avenue, Australian Technology Park, Eveleigh 1430, Australia.

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http://dx.doi.org/10.1016/j.bbrc.2004.04.077DOI Listing
June 2004

Expressing functional siRNAs in mammalian cells using convergent transcription.

BMC Biotechnol 2003 Nov 6;3:21. Epub 2003 Nov 6.

Johnson and Johnson Research Pty Ltd, 1 Central Ave, Australian Technology Park, Eveleigh, NSW 1430, Australia.

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http://dx.doi.org/10.1186/1472-6750-3-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC280659PMC
November 2003

E6AP gene suppression and characterization with in vitro selected hammerhead ribozymes.

Cancer Gene Ther 2003 Sep;10(9):707-16

Department of Medicine, St Vincent's Hospital Clinical School, University of New South Wales, Sydney 2010, Australia.

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http://dx.doi.org/10.1038/sj.cgt.7700623DOI Listing
September 2003

Optimisation of the 10-23 DNAzyme-substrate pairing interactions enhanced RNA cleavage activity at purine-cytosine target sites.

Nucleic Acids Res 2003 Jun;31(11):2883-9

Johnson and Johnson Research Laboratories, Australian Technology Park, Level 4, One Central Avenue, Eveleigh, NSW 1430, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC156713PMC
http://dx.doi.org/10.1093/nar/gkg378DOI Listing
June 2003