Murray Grossman

Murray Grossman

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Murray Grossman

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Genetic predictors of survival in behavioral variant frontotemporal degeneration.

Neurology 2019 Oct 19;93(18):e1707-e1714. Epub 2019 Sep 19.

From the Department of Biostatistics, Epidemiology, and Informatics (C.C., S.X.X.), Department of Neurology (C.T.M., D.J.I., M.G., L.M.M.), Penn Frontotemporal Degeneration Center (C.T.M., D.J.I., M.G., L.M.M.), Translational Neuropathology Research Laboratory (E.B.L.), Department of Pathology and Laboratory Medicine (V.M.V.D., E.B.L., J.Q.T., V.M.-Y.L.), and Center for Neurodegenerative Disease Research (V.M.V.D., E.S., E.B.L., J.Q.T., V.M.-Y.L.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1212/WNL.0000000000008387DOI Listing
October 2019

Diffusion Tensor MRI to Distinguish Progressive Supranuclear Palsy from α-Synucleinopathies.

Radiology 2019 Oct 15:190406. Epub 2019 Oct 15.

From the Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Sölvegatan 19, 22100 Lund, Sweden (N.S., S.H., D.v.W., O.H.); Penn Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (N.S., D.J.I., M.G., C.T.M.); Memory Clinic, Skåne University Hospital, Malmö, Sweden (S.H., O.H.); Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (D.J.I., E.B.L., J.Q.T.); Department of Diagnostic Radiology, Lund University, Lund, Sweden (T.R., D.v.W., M.N.); Wellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London, England (J.A.C.); Parkinson's Disease and Movement Disorders Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.F.D., M.A.S.); Alzheimer's Disease Core Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (E.B.L., J.Q.T.); and Queensland Brain Institute, University of Queensland and Mater Misericordiae, Brisbane, Queensland, Australia (P.J.N.).

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http://dx.doi.org/10.1148/radiol.2019190406DOI Listing
October 2019

Cognitive and Neuroanatomic Accounts of Referential Communication in Focal Dementia.

eNeuro 2019 Sep/Oct;6(5). Epub 2019 Sep 26.

Penn Frontotemporal Degeneration Center and Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104

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http://dx.doi.org/10.1523/ENEURO.0488-18.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794081PMC
September 2019

A longitudinal study of speech production in primary progressive aphasia and behavioral variant frontotemporal dementia.

Brain Lang 2019 07 7;194:46-57. Epub 2019 May 7.

Penn Frontotemporal Degeneration Center and Department of Neurology, Perelman School of Medicine of the University of Pennsylvania, United States.

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http://dx.doi.org/10.1016/j.bandl.2019.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656376PMC
July 2019

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration.

Alzheimers Dement 2019 Jul 1. Epub 2019 Jul 1.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.04.007DOI Listing
July 2019

Empiric Methods to Account for Pre-analytical Variability in Digital Histopathology in Frontotemporal Lobar Degeneration.

Front Neurosci 2019 3;13:682. Epub 2019 Jul 3.

Penn Digital Neuropathology Laboratory, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fnins.2019.00682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616086PMC
July 2019

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:
Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 Jun 9;137(6):879-899. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9
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http://dx.doi.org/10.1007/s00401-019-01962-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533145PMC
June 2019

Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia.

Ann Neurol 2019 May 28;85(5):630-643. Epub 2019 Mar 28.

Penn Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1002/ana.25465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538935PMC
May 2019

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.

Alzheimers Dement 2019 May 11. Epub 2019 May 11.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15525260193004
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http://dx.doi.org/10.1016/j.jalz.2019.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842665PMC
May 2019

Clinical Correlates of Alzheimer's Disease Cerebrospinal Fluid Analytes in Primary Progressive Aphasia.

Front Neurol 2019 10;10:485. Epub 2019 May 10.

Department of Neurology and Penn FTD Center, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fneur.2019.00485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524001PMC
May 2019

Persistent and Progressive Outer Retina Thinning in Frontotemporal Degeneration.

Front Neurosci 2019 4;13:298. Epub 2019 Apr 4.

Department of Neurology, Frontotemporal Lobar Degeneration Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fnins.2019.00298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459211PMC
April 2019

Longitudinal Changes in Semantic Concreteness in Semantic Variant Primary Progressive Aphasia (svPPA).

eNeuro 2018 Nov-Dec;5(6). Epub 2018 Jan 10.

Department of Neurology and Penn Frontotemporal Degeneration Center.

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http://dx.doi.org/10.1523/ENEURO.0197-18.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377408PMC
March 2019

Occupational attainment influences longitudinal decline in behavioral variant frontotemporal degeneration.

Brain Imaging Behav 2019 Feb;13(1):293-301

Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, 3 West Gates, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s11682-018-9852-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521965PMC
February 2019

Elevated YKL-40 and low sAPPβ:YKL-40 ratio in antemortem cerebrospinal fluid of patients with pathologically confirmed FTLD.

J Neurol Neurosurg Psychiatry 2019 Feb 8;90(2):180-186. Epub 2018 Oct 8.

Sant Pau Memory Unit, Department of Neurology, Institut d'Investigacions Biomèdiques Sant Pau - Hospital de Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2018-318993
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http://dx.doi.org/10.1136/jnnp-2018-318993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351153PMC
February 2019

Longitudinal structural gray matter and white matter MRI changes in presymptomatic progranulin mutation carriers.

Neuroimage Clin 2018 15;19:497-506. Epub 2018 May 15.

Penn Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2018.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029561PMC
January 2019

Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology.

Alzheimers Dement 2019 01 12;15(1):55-64. Epub 2018 Oct 12.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.

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http://dx.doi.org/10.1016/j.jalz.2018.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333489PMC
January 2019

Amyotrophic lateral sclerosis - a multisystem neurodegenerative disorder.

Authors:
Murray Grossman

Nat Rev Neurol 2019 01;15(1):5-6

Penn Frontotemporal Degeneration Center and Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA.

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http://www.nature.com/articles/s41582-018-0103-y
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http://dx.doi.org/10.1038/s41582-018-0103-yDOI Listing
January 2019

Validated automatic speech biomarkers in primary progressive aphasia.

Ann Clin Transl Neurol 2019 01 24;6(1):4-14. Epub 2018 Nov 24.

Penn Frontotemporal Degeneration Center Department of Neurology University of Pennsylvania Philadelphia Pennsylvania.

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http://dx.doi.org/10.1002/acn3.653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331511PMC
January 2019

Converging Patterns of α-Synuclein Pathology in Multiple System Atrophy.

J Neuropathol Exp Neurol 2018 11;77(11):1005-1016

Center for Neurodegenerative Disease Research (CNDR), University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1093/jnen/nly080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181179PMC
November 2018

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia.

Ann Neurol 2018 11;84(5):729-740

Alzheimer center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, VU University, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/ana.25333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354051PMC
November 2018

Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease.

Alzheimers Dement 2018 08 28;14(8):1052-1062. Epub 2018 Mar 28.

Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA; Department of Pathology, Peking University Health Science Centre and Third Hospital, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097943PMC
August 2018

Evaluation of Linguistic Markers of Word-Finding Difficulty and Cognition in Parkinson's Disease.

J Speech Lang Hear Res 2018 07;61(7):1691-1699

Department of Neurology and the Penn Frontotemporal Degenerative Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1044/2018_JSLHR-L-17-0304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195062PMC
July 2018

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Authors:
Cyril Pottier Xiaolai Zhou Ralph B Perkerson Matt Baker Gregory D Jenkins Daniel J Serie Roberta Ghidoni Luisa Benussi Giuliano Binetti Adolfo López de Munain Miren Zulaica Fermin Moreno Isabelle Le Ber Florence Pasquier Didier Hannequin Raquel Sánchez-Valle Anna Antonell Albert Lladó Tammee M Parsons NiCole A Finch Elizabeth C Finger Carol F Lippa Edward D Huey Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Robert A Rissman Jaroslaw Slawek Emilia Sitek Peter Johannsen Jørgen E Nielsen Yingxue Ren Marka van Blitterswijk Mariely DeJesus-Hernandez Elizabeth Christopher Melissa E Murray Kevin F Bieniek Bret M Evers Camilla Ferrari Sara Rollinson Anna Richardson Elio Scarpini Giorgio G Fumagalli Alessandro Padovani John Hardy Parastoo Momeni Raffaele Ferrari Francesca Frangipane Raffaele Maletta Maria Anfossi Maura Gallo Leonard Petrucelli EunRan Suh Oscar L Lopez Tsz H Wong Jeroen G J van Rooij Harro Seelaar Simon Mead Richard J Caselli Eric M Reiman Marwan Noel Sabbagh Mads Kjolby Anders Nykjaer Anna M Karydas Adam L Boxer Lea T Grinberg Jordan Grafman Salvatore Spina Adrian Oblak M-Marsel Mesulam Sandra Weintraub Changiz Geula John R Hodges Olivier Piguet William S Brooks David J Irwin John Q Trojanowski Edward B Lee Keith A Josephs Joseph E Parisi Nilüfer Ertekin-Taner David S Knopman Benedetta Nacmias Irene Piaceri Silvia Bagnoli Sandro Sorbi Marla Gearing Jonathan Glass Thomas G Beach Sandra E Black Mario Masellis Ekaterina Rogaeva Jean-Paul Vonsattel Lawrence S Honig Julia Kofler Amalia C Bruni Julie Snowden David Mann Stuart Pickering-Brown Janine Diehl-Schmid Juliane Winkelmann Daniela Galimberti Caroline Graff Linn Öijerstedt Claire Troakes Safa Al-Sarraj Carlos Cruchaga Nigel J Cairns Jonathan D Rohrer Glenda M Halliday John B Kwok John C van Swieten Charles L White Bernardino Ghetti Jill R Murell Ian R A Mackenzie Ging-Yuek R Hsiung Barbara Borroni Giacomina Rossi Fabrizio Tagliavini Zbigniew K Wszolek Ronald C Petersen Eileen H Bigio Murray Grossman Vivianna M Van Deerlin William W Seeley Bruce L Miller Neill R Graff-Radford Bradley F Boeve Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Lancet Neurol 2018 06 30;17(6):548-558. Epub 2018 Apr 30.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30126-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237181PMC
June 2018

Primary Progressive Aphasia and Stroke Aphasia.

Continuum (Minneap Minn) 2018 06;24(3, BEHAVIORAL NEUROLOGY AND PSYCHIATRY):745-767

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http://dx.doi.org/10.1212/CON.0000000000000618DOI Listing
June 2018

Cognitive and Affective Perspective-Taking: Evidence for Shared and Dissociable Anatomical Substrates.

Front Neurol 2018 25;9:491. Epub 2018 Jun 25.

Penn Department of Neurology and Frontotemporal Degeneration Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fneur.2018.00491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026651PMC
June 2018

Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases.

Brain Pathol 2018 03 19;28(2):274-283. Epub 2017 Jan 19.

Center for Neurodegenerative Disease Research, Institute on Aging and Department of Pathology & Laboratory Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1111/bpa.12482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484758PMC
March 2018

Production of verbs related to body movement in amyotrophic lateral sclerosis (ALS) and Parkinson's Disease (PD).

Cortex 2018 03 8;100:127-139. Epub 2017 Sep 8.

Department of Neurology and Penn Frontotemporal Degeneration Center, University of Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cortex.2017.08.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834347PMC
March 2018

Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease.

Neurobiol Aging 2018 03 21;63:75-87. Epub 2017 Nov 21.

Penn Frontotemporal Degeneration Center, University of Pennsylvania, Philadelphia, PA, USA; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801003PMC
March 2018

CSF tau and β-amyloid predict cerebral synucleinopathy in autopsied Lewy body disorders.

Neurology 2018 03 21;90(12):e1038-e1046. Epub 2018 Feb 21.

From Penn Frontotemporal Degeneration Center (D.J.I., N.N., C.T.M., M.G.), Alzheimer's Disease Core Center (D.A.W., J.Q.T.), Department of Neurology (D.J.I., D.C., R.S.A., C.T.M., D.A.W., D.W., A.C.-P., M.S., A.S., H.I.H., M.G.), Penn Morris K. Udall Parkinson's Disease Research Center of Excellence (D.J.I., R.S.A., C.T.M., D.W., A.C.-P., J.E.D., M.G., J.Q.T.), Center for Neurodegenerative Disease Research (L.M.S., J.Q.T.), Translational Neuropathology Research Laboratory (E.B.L.), Department of Pathology and Laboratory Medicine (E.B.L., L.M.S., J.Q.T.), and Department of Biostatistics and Epidemiology Perelman School of Medicine (S.X.X.), University of Pennsylvania; and Parkinson's Disease Research, Education and Clinical Center (D.W., J.E.D.), Michael J. Crescenz VA Medical Center, Philadelphia, PA.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874449PMC
March 2018

Tau PET imaging predicts cognition in atypical variants of Alzheimer's disease.

Hum Brain Mapp 2018 02 6;39(2):691-708. Epub 2017 Nov 6.

Penn Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, 19104.

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http://dx.doi.org/10.1002/hbm.23874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764792PMC
February 2018

Evidence of semantic processing impairments in behavioural variant frontotemporal dementia and Parkinson's disease.

Curr Opin Neurol 2017 Dec;30(6):617-622

Department of Neurology and Penn Frontotemporal Degeneration Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/WCO.0000000000000498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909813PMC
December 2017

Optical coherence tomography identifies outer retina thinning in frontotemporal degeneration.

Neurology 2017 Oct 8;89(15):1604-1611. Epub 2017 Sep 8.

From the Scheie Eye Institute, Department of Ophthalmology (B.J.K., D.S., E.D., J.D.L., A.R.R., W.P., G.-S.Y., T.S.A., J.L.D.), and Frontotemporal Lobar Degeneration Center, Department of Neurology (D.J.I., M.G.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1212/WNL.0000000000004500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634666PMC
October 2017

Linguistic Aspects of Primary Progressive Aphasia.

Authors:
Murray Grossman

Annu Rev Linguist 2018 20;4:377-403. Epub 2017 Oct 20.

Penn Frontotemporal Degeneration Center and Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania 19104.

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http://dx.doi.org/10.1146/annurev-linguistics-011516-034253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089544PMC
October 2017

Brain network efficiency is influenced by the pathologic source of corticobasal syndrome.

Neurology 2017 Sep 4;89(13):1373-1381. Epub 2017 Aug 4.

From the Departments of Psychology (J.D.M.), Electrical and Systems Engineering (W.H., D.S.B.), Neurology (C.O., M.G., C.T.M.), and Bioengineering (D.S.B.), Penn Frontotemporal Degeneration Center (C.O., M.G., C.T.M.), and Penn Image Computing and Science Lab (J.G.), University of Pennsylvania, Philadelphia; and Institute for Data, Systems, and Society (S.S., A.R.), Massachusetts Institute of Technology, Cambridge.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000004324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649755PMC
September 2017

Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration.

Acta Neuropathol Commun 2017 09 6;5(1):68. Epub 2017 Sep 6.

Center for Neurodegenerative Disease Research and Institute on Aging, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1186/s40478-017-0471-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586052PMC
September 2017

Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration.

Ann Neurol 2017 Aug 19;82(2):247-258. Epub 2017 Aug 19.

Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1002/ana.24996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776747PMC
August 2017

Automatic measurement of prosody in behavioral variant FTD.

Neurology 2017 Aug 19;89(7):650-656. Epub 2017 Jul 19.

From the Penn Frontotemporal Degeneration Center, Department of Neurology (N.N., S.A., C.J., D.J.I., M.G.), and Linguistic Data Consortium (M.L.), University of Pennsylvania, Philadelphia.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000004236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562969PMC
August 2017

Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia.

Neurology 2017 Jun 17;88(24):2276-2284. Epub 2017 May 17.

From the Department of Neurology (L.A.A.G.), University Medical Center Groningen, University of Groningen, the Netherlands; Penn Frontotemporal Degeneration Center, Department of Neurology (L.A.A.G., D.J.I., C.T.M., S.A., K.R., M.G.), Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine (D.J.I., V.M.V.D., J.Q.T.), Alzheimer's Disease Center (D.A.W.), Department of Neurology, and Translational Pathology Laboratory, Perelman School of Medicine (E.B.L.), University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1212/WNL.0000000000004034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567322PMC
June 2017

Baseline Performance Predicts tDCS-Mediated Improvements in Language Symptoms in Primary Progressive Aphasia.

Front Hum Neurosci 2017 30;11:347. Epub 2017 Jun 30.

Laboratory for Cognition and Neural Stimulation, Department of Neurology, University of PennsylvaniaPhiladelphia, PA, United States.

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http://dx.doi.org/10.3389/fnhum.2017.00347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492829PMC
June 2017

Semantic Feature Training in Combination with Transcranial Direct Current Stimulation (tDCS) for Progressive Anomia.

Front Hum Neurosci 2017 16;11:253. Epub 2017 May 16.

Eleanor M. Saffran Center for Cognitive Neuroscience, Temple University, PhiladelphiaPA, USA.

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http://dx.doi.org/10.3389/fnhum.2017.00253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432627PMC
May 2017

Category learning in Alzheimer's disease and normal cognitive aging depends on initial experience of feature variability.

Neuropsychologia 2017 04 6;98:98-110. Epub 2016 Jul 6.

Penn Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.neuropsychologia.2016.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218992PMC
April 2017

Poly(GP) proteins are a useful pharmacodynamic marker for -associated amyotrophic lateral sclerosis.

Sci Transl Med 2017 03;9(383)

Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1126/scitranslmed.aai7866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576451PMC
March 2017

Dissociable substrates underlie the production of abstract and concrete nouns.

Brain Lang 2017 02 29;165:45-54. Epub 2016 Nov 29.

Department of Neurology and Penn Frontotemporal Degeneration Center, University of Pennsylvania, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bandl.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237409PMC
February 2017

Decision-Making Deficits Associated with Amyloidosis in Lewy Body Disorders.

Front Hum Neurosci 2016 11;10:693. Epub 2017 Jan 11.

Penn Frontotemporal Degeneration Center, University of Pennsylvania Perelman School of Medicine Philadelphia, PA, USA.

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http://dx.doi.org/10.3389/fnhum.2016.00693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225123PMC
January 2017

Multimodal evaluation demonstrates in vivo F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration.

Acta Neuropathol 2016 12 4;132(6):935-937. Epub 2016 Nov 4.

Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, 3 West Gates, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s00401-016-1640-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154298PMC
December 2016

Computerized assessment of goal-directed behavior in Parkinson's disease.

J Clin Exp Neuropsychol 2016 11 7;38(9):1015-25. Epub 2016 Jun 7.

a Department of Neurology , Perelman School of Medicine, University of Pennsylvania , Philadelphia , PA , USA.

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http://dx.doi.org/10.1080/13803395.2016.1184232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979569PMC
November 2016

Transcranial direct current stimulation for the treatment of primary progressive aphasia: An open-label pilot study.

Brain Lang 2016 Nov 12;162:35-41. Epub 2016 Aug 12.

Laboratory for Cognition and Neural Stimulation, Center for Cognitive Neuroscience, University of Pennsylvania, United States; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bandl.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204261PMC
November 2016

Arterial spin labeling perfusion predicts longitudinal decline in semantic variant primary progressive aphasia.

J Neurol 2016 Oct 5;263(10):1927-38. Epub 2016 Jul 5.

Department of Neurology, Penn Frontotemporal Degeneration Center, University of Pennsylvania Perelman School of Medicine, 3 West Gates, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s00415-016-8221-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097861PMC
October 2016

Cognitive reserve in frontotemporal degeneration: Neuroanatomic and neuropsychological evidence.

Neurology 2016 Oct 28;87(17):1813-1819. Epub 2016 Sep 28.

From the Department of Neurology, Penn Frontotemporal Degeneration Center (K.P., L.M., C.O., K.T., K.F., D.I., M.G., C.T.M.), and Department of Pathology & Laboratory Medicine, Center for Neurodegenerative Disease Research (V.V.D., E.B.L., J.Q.T., V.M.-Y.L., D.I.), University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1212/WNL.0000000000003250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089523PMC
October 2016

Multimodal imaging evidence of pathology-mediated disease distribution in corticobasal syndrome.

Neurology 2016 Sep 19;87(12):1227-34. Epub 2016 Aug 19.

From the Department of Neurology (C.T.M., C.B., R.G.G., J.W., K.F., K.R., D.A.W., D.J.I., M.G.) and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine (J.B.T., L.S., D.J.I., E.B.L., J.Q.T.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035978PMC
http://dx.doi.org/10.1212/WNL.0000000000003119DOI Listing
September 2016

Dissociation of quantifiers and object nouns in speech in focal neurodegenerative disease.

Neuropsychologia 2016 08 11;89:141-152. Epub 2016 Jun 11.

Department of Neurology and the Penn Frontotemporal Degeneration Center, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neuropsychologia.2016.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996733PMC
August 2016

A race effect on amyloid deposition?

Neurology 2016 08 1;87(5):454-5. Epub 2016 Jul 1.

From INSERM, U1077 (G.C.); Université de Caen Basse-Normandie, UMR-S1077 (G.C.); Ecole Pratique des Hautes Etudes, UMR-S1077 (G.C.); CHU de Caen, U1077 (G.C.), Caen, France; and Department of Neurology and Penn Frontotemporal Degeneration Center (M.G.), University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1212/WNL.0000000000002924DOI Listing
August 2016

Resting State Brain Entropy Alterations in Relapsing Remitting Multiple Sclerosis.

PLoS One 2016 4;11(1):e0146080. Epub 2016 Jan 4.

Department of Psychology, Hangzhou Normal University, Hangzhou, Zhejiang Province, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146080PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699711PMC
July 2016

Predicting disease progression in progressive supranuclear palsy in multicenter clinical trials.

Parkinsonism Relat Disord 2016 07 18;28:41-48. Epub 2016 Apr 18.

Memory and Aging Center, Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, CA, USA 94158.

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http://dx.doi.org/10.1016/j.parkreldis.2016.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914418PMC
July 2016

Cognitive and anatomic double dissociation in the representation of concrete and abstract words in semantic variant and behavioral variant frontotemporal degeneration.

Neuropsychologia 2016 Apr 2;84:244-51. Epub 2016 Mar 2.

Department of Neurology and Penn Frontotemporal Degeneration Center, University of Pennsylvania, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neuropsychologia.2016.02.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808428PMC
April 2016

Acoustic richness modulates the neural networks supporting intelligible speech processing.

Hear Res 2016 Mar 23;333:108-117. Epub 2015 Dec 23.

Department of Otolaryngology, Washington University in St. Louis, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.heares.2015.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798890PMC
March 2016

The Two Sides of Sensory-Cognitive Interactions: Effects of Age, Hearing Acuity, and Working Memory Span on Sentence Comprehension.

Front Psychol 2016 29;7:236. Epub 2016 Feb 29.

Department of Psychology and Volen National Center for Complex Systems, Brandeis University, Waltham MA, USA.

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http://dx.doi.org/10.3389/fpsyg.2016.00236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770018PMC
March 2016

Causal Evidence for a Mechanism of Semantic Integration in the Angular Gyrus as Revealed by High-Definition Transcranial Direct Current Stimulation.

J Neurosci 2016 Mar;36(13):3829-38

Center for Cognitive Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, and

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http://dx.doi.org/10.1523/JNEUROSCI.3120-15.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812139PMC
March 2016