Murat Iskar

Murat Iskar

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Murat Iskar

Murat Iskar

Publications by authors named "Murat Iskar"

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19Publications

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CD8 T-cells of CLL-bearing mice acquire a transcriptional program of T-cell activation and exhaustion.

Leuk Lymphoma 2019 Sep 13:1-6. Epub 2019 Sep 13.

Department of Molecular Genetics, German Cancer Research Center (DKFZ) , Heidelberg , Germany.

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http://dx.doi.org/10.1080/10428194.2019.1660972DOI Listing
September 2019

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.

J Cell Biol 2016 Nov 8;215(4):543-558. Epub 2016 Nov 8.

Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany

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http://dx.doi.org/10.1083/jcb.201601090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119934PMC
November 2016

CART-a chemical annotation retrieval toolkit.

Bioinformatics 2016 09 2;32(18):2869-71. Epub 2016 Jun 2.

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany Molecular Medicine Partnership Unit, University of Heidelberg and European Molecular Biology Laboratory, Heidelberg, Germany Max Delbrück Centre for Molecular Medicine, Berlin, Germany Department of Bioinformatics, Biocenter, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btw233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018367PMC
September 2016

Discovery and validation of the antimetastatic activity of citalopram in colorectal cancer.

Mol Cell Oncol 2015 Apr-Jun;2(2):e975080. Epub 2015 Feb 11.

Department of Microbial and Molecular Systems (M2S); KU Leuven ; Leuven, Belgium.

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http://dx.doi.org/10.4161/23723556.2014.975080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904995PMC
June 2016

Spatiotemporal variation of mammalian protein complex stoichiometries.

Genome Biol 2016 Mar 14;17:47. Epub 2016 Mar 14.

European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s13059-016-0912-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791834PMC
March 2016

Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats.

Cell Syst 2015 Sep 17;1(3):224-37. Epub 2015 Sep 17.

European Molecular Biology Laboratory, Structural and Computational Biology Unit, Meyerhofstrasse 1, Heidelberg 69117, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2015.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802414PMC
September 2015

Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs).

Mol Cell Proteomics 2015 May 9;14(5):1350-60. Epub 2015 Mar 9.

From the ‡European Molecular Biology Laboratory, Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117 Heidelberg, Germany;

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http://dx.doi.org/10.1074/mcp.M114.042499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424404PMC
May 2015

Luminal signalling links cell communication to tissue architecture during organogenesis.

Nature 2014 Nov 22;515(7525):120-4. Epub 2014 Oct 22.

European Molecular Biology Laboratory Heidelberg, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature13852DOI Listing
November 2014

Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling.

Cancer Res 2014 Oct 18;74(20):5690-9. Epub 2014 Jul 18.

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse, Heidelberg, Germany. Max-Delbrück-Centre (MDC) for Molecular Medicine, Berlin, Germany.

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http://cancerres.aacrjournals.org/content/early/2014/07/18/0
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http://cancerres.aacrjournals.org/content/74/20/5690.full.pd
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-3540DOI Listing
October 2014

DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data.

Bioinformatics 2013 Jan 4;29(1):132-4. Epub 2012 Nov 4.

European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Cambridge, UK CB10 1SD.

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http://dx.doi.org/10.1093/bioinformatics/bts656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530913PMC
January 2013

Drug discovery in the age of systems biology: the rise of computational approaches for data integration.

Curr Opin Biotechnol 2012 Aug 5;23(4):609-16. Epub 2011 Dec 5.

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.copbio.2011.11.010DOI Listing
August 2012

Prediction of drug combinations by integrating molecular and pharmacological data.

PLoS Comput Biol 2011 Dec 29;7(12):e1002323. Epub 2011 Dec 29.

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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http://dx.doi.org/10.1371/journal.pcbi.1002323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248384PMC
December 2011

Network neighbors of drug targets contribute to drug side-effect similarity.

PLoS One 2011 13;6(7):e22187. Epub 2011 Jul 13.

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022187PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135612PMC
November 2011

Drug-induced regulation of target expression.

PLoS Comput Biol 2010 Sep 9;6(9). Epub 2010 Sep 9.

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.1371/journal.pcbi.1000925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936514PMC
September 2010