Munetaka Kunishima

Munetaka Kunishima

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Munetaka Kunishima

Publications by authors named "Munetaka Kunishima"

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Development of Triazinone-Based Condensing Reagents for Amide Formation.

J Org Chem 2019 Dec 8;84(23):15042-15051. Epub 2019 Nov 8.

Faculty of Pharmaceutical Sciences , Institute of Medical, Pharmaceutical, and Health Sciences Kanazawa University , Kakuma-machi , Kanazawa 920-1192 , Japan.

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http://dx.doi.org/10.1021/acs.joc.9b01261DOI Listing
December 2019

Substitution of the Dimethylamino Group in Gramines and One-Pot Cyclization to Tetrahydro-β-carbolines Using a Triazine-Based Activating Agent.

J Org Chem 2019 Jul 25;84(13):8380-8391. Epub 2019 Jun 25.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences , Kanazawa University , Kakuma-machi, Kanazawa 920-1192 , Japan.

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http://dx.doi.org/10.1021/acs.joc.9b00039DOI Listing
July 2019

Phototriggered Active Alkyne Generation from Cyclopropenones with Visible Light-Responsive Photocatalysts.

Org Lett 2019 Jun 22;21(11):4101-4105. Epub 2019 May 22.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences , Kanazawa University , Kakuma-machi, Kanazawa 920-1192 , Japan.

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http://dx.doi.org/10.1021/acs.orglett.9b01280DOI Listing
June 2019

Development of a Storable Triazinone-Based Reagent for O- p-Methoxybenzylation under Mild Heating Conditions.

Org Lett 2019 05 22;21(9):3093-3097. Epub 2019 Apr 22.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences , Kanazawa University , Kakuma-machi, Kanazawa 920-1192 , Japan.

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http://dx.doi.org/10.1021/acs.orglett.9b00732DOI Listing
May 2019

Phototriggered Ketone Formation from an Aminocyclopropenone and a Carboxylic Acid.

J Org Chem 2018 Nov 10;83(21):13595-13603. Epub 2018 Oct 10.

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http://dx.doi.org/10.1021/acs.joc.8b02250DOI Listing
November 2018

Combination Metabolomics Approach for Identifying Endogenous Substrates of Carnitine/Organic Cation Transporter OCTN1.

Pharm Res 2018 Oct 2;35(11):224. Epub 2018 Oct 2.

Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.

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http://dx.doi.org/10.1007/s11095-018-2507-1DOI Listing
October 2018

Cooperation of the Neutral and the Cationic Leaving Group Pathways in Acid-Catalyzed O-Benzylation of TriBOT.

J Org Chem 2018 09 25;83(17):10684-10687. Epub 2018 Jul 25.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences , Kanazawa University , Kakuma-machi, Kanazawa 920-1192 , Japan.

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http://dx.doi.org/10.1021/acs.joc.8b01505DOI Listing
September 2018

Development of triazine-based esterifying reagents containing pyridines as a nucleophilic catalyst.

Org Biomol Chem 2018 09;16(35):6569-6575

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.

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http://dx.doi.org/10.1039/c8ob01660gDOI Listing
September 2018

Development of radioiodine labeled acetaminophen for specific, high-contrast imaging of malignant melanoma.

Nucl Med Biol 2018 04 3;59:16-21. Epub 2018 Jan 3.

Department of Health Sciences, College of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan; Biomedical Imaging Research Center, University of Fukui, Fukui, Japan.

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http://dx.doi.org/10.1016/j.nucmedbio.2017.12.008DOI Listing
April 2018

An Isolable and Bench-Stable Epoxidizing Reagent Based on Triazine: Triazox.

Org Lett 2018 04 23;20(7):2015-2019. Epub 2018 Mar 23.

Faculty of Pharmaceutical Sciences , Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University , Kakuma-machi, Kanazawa 920-1192 , Japan.

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http://pubs.acs.org/doi/10.1021/acs.orglett.8b00560
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http://dx.doi.org/10.1021/acs.orglett.8b00560DOI Listing
April 2018

Triazine-Based Cationic Leaving Group: Synergistic Driving Forces for Rapid Formation of Carbocation Species.

J Org Chem 2018 04 9;83(8):4568-4580. Epub 2018 Apr 9.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences , Kanazawa University , Kakuma-machi, Kanazawa 920-1192 , Japan.

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http://dx.doi.org/10.1021/acs.joc.8b00331DOI Listing
April 2018

Development of Triazine-Based Benzylating Reagents Possessing t-Butyl Group on the Triazine Core: Thermally Controllable Reagents for the Initiation of Reaction.

Chem Pharm Bull (Tokyo) 2018 ;66(3):303-308

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University.

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http://dx.doi.org/10.1248/cpb.c17-00897DOI Listing
March 2018

Phototriggered Dehydration Condensation Using an Aminocyclopropenone.

Org Lett 2017 09 1;19(18):4912-4915. Epub 2017 Sep 1.

Institute for Frontier Science Initiative and ‡Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University , Kakuma-machi, Kanazawa 920-1192 Japan.

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http://dx.doi.org/10.1021/acs.orglett.7b02383DOI Listing
September 2017

Chemo-enzymatic synthesis of a glycosylated peptide containing a complex N-glycan based on unprotected oligosaccharides by using DMT-MM and Endo-M.

Glycoconj J 2017 08 18;34(4):481-487. Epub 2017 May 18.

Research Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Ishikawa, 921-8836, Japan.

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http://link.springer.com/10.1007/s10719-017-9770-y
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http://dx.doi.org/10.1007/s10719-017-9770-yDOI Listing
August 2017

Development of a method for the synthesis of 2,4,5-trisubstituted oxazoles composed of carboxylic acid, amino acid, and boronic acid.

Beilstein J Org Chem 2017 27;13:1478-1485. Epub 2017 Jul 27.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.

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http://dx.doi.org/10.3762/bjoc.13.146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550800PMC
July 2017

Study of O-Allylation Using Triazine-Based Reagents.

Chem Pharm Bull (Tokyo) 2017 ;65(1):112-115

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University.

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http://dx.doi.org/10.1248/cpb.c16-00744DOI Listing
February 2017

Mild Amide-Cleavage Reaction Mediated by Electrophilic Benzylation.

Chemistry 2016 Sep 16;22(39):14042-14047. Epub 2016 Aug 16.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.

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http://dx.doi.org/10.1002/chem.201603120DOI Listing
September 2016

Potent triazine-based dehydrocondensing reagents substituted by an amido group.

Beilstein J Org Chem 2016 24;12:1897-1903. Epub 2016 Aug 24.

Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima Chuo-ku, Kobe 655-8586, Japan.

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http://dx.doi.org/10.3762/bjoc.12.179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082469PMC
August 2016

Increased Plasma Concentrations of Unbound SN-38, the Active Metabolite of Irinotecan, in Cancer Patients with Severe Renal Failure.

Pharm Res 2016 Feb 3;33(2):269-82. Epub 2015 Sep 3.

Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.

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http://dx.doi.org/10.1007/s11095-015-1785-0DOI Listing
February 2016

Study of the Reactivities of Acid-Catalyzed O-Benzylating Reagents Based on Structural Isomers of 1,3,5-Triazine.

J Org Chem 2015 Nov 20;80(21):11200-5. Epub 2015 Oct 20.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University , Kakuma-machi, Kanazawa 920-1192, Japan.

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http://dx.doi.org/10.1021/acs.joc.5b02059DOI Listing
November 2015

Specific labeling of streptavidin for better understanding of ligand modification in modular method for affinity labeling (MoAL).

Chem Pharm Bull (Tokyo) 2014 ;62(11):1146-50

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University.

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http://dx.doi.org/10.1248/cpb.c14-00468DOI Listing
June 2015

Development of a new benzylating reagent spontaneously releasing benzyl cation equivalents at room temperature.

Chemistry 2014 Sep 8;20(38):12274-8. Epub 2014 Aug 8.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192 (Japan).

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http://dx.doi.org/10.1002/chem.201403158DOI Listing
September 2014

Role of linkers in tertiary amines that mediate or catalyze 1,3,5-triazine-based amide-forming reactions.

J Org Chem 2014 Apr 31;79(8):3709-14. Epub 2014 Mar 31.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University , Kakuma-machi, Kanazawa 920-1192, Japan.

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http://dx.doi.org/10.1021/jo500376mDOI Listing
April 2014

Study of 1,3,5-triazine-based catalytic amide-forming reactions: effect of solvents and basicity of reactants.

Chem Pharm Bull (Tokyo) 2013 ;61(8):882-6

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920–1192, Japan.

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http://dx.doi.org/10.1248/cpb.c13-00368DOI Listing
February 2014

Study on 1,3,5-triazine chemistry in dehydrocondensation: gauche effect on the generation of active triazinylammonium species.

Chemistry 2012 Dec 11;18(49):15856-67. Epub 2012 Oct 11.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Japan.

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http://dx.doi.org/10.1002/chem.201202236DOI Listing
December 2012

One-pot preparation of Oxazol-5(4H)-ones from amino acids in aqueous solvents.

Chem Pharm Bull (Tokyo) 2012 ;60(7):907-12

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan.

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http://dx.doi.org/10.1248/cpb.c12-00291DOI Listing
November 2012

A novel acid-catalyzed O-benzylating reagent with the smallest unit of imidate structure.

Org Lett 2012 Oct 20;14(19):5026-9. Epub 2012 Sep 20.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.

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http://dx.doi.org/10.1021/ol302222pDOI Listing
October 2012

N-Isopropyl-p-iodoamphetamine hydrochloride Is predominantly metabolized by CYP2C19.

Drug Metab Dispos 2012 May 31;40(5):843-6. Epub 2012 Jan 31.

Department of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama 350-1298, Japan.

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http://dx.doi.org/10.1124/dmd.111.043893DOI Listing
May 2012

Substrate-selective dehydrocondensation at the interface of micelles and emulsions of common surfactants.

Angew Chem Int Ed Engl 2012 Feb 20;51(9):2080-3. Epub 2012 Jan 20.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan.

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http://dx.doi.org/10.1002/anie.201107706DOI Listing
February 2012

Labeling study of avidin by modular method for affinity labeling (MoAL).

Bioorg Med Chem Lett 2010 Dec 25;20(23):7050-3. Epub 2010 Sep 25.

Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.bmcl.2010.09.109DOI Listing
December 2010

Convenient modular method for affinity labeling (MoAL method) based on a catalytic amidation.

Chem Commun (Camb) 2009 Oct 19(37):5597-9. Epub 2009 Aug 19.

Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.

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http://dx.doi.org/10.1039/b912908aDOI Listing
October 2009

Convenient one-pot synthesis of 2-oxazolines from carboxylic acids.

Chem Pharm Bull (Tokyo) 2008 Dec;56(12):1735-7

Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Chuo-ku, Koba, Japan.

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http://dx.doi.org/10.1248/cpb.56.1735DOI Listing
December 2008

[Studies on reaction control and development of new practical reagents based on characteristics of reaction field].

Yakugaku Zasshi 2008 Mar;128(3):425-38

Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan.

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http://dx.doi.org/10.1248/yakushi.128.425DOI Listing
March 2008

Immobilized triazine-type dehydrocondensing reagents for carboxamide formation: ROMP-Trz-Cl and ROMP(OH)-Trz-Cl.

Chem Pharm Bull (Tokyo) 2007 May;55(5):825-8

Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe 650-8586, Japan.

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http://dx.doi.org/10.1248/cpb.55.825DOI Listing
May 2007

A study on medicinal plants from Malaysia focused on Acalypha siamensis Oliv. ex Gage. isolation and structure of a new tetraterpene, acalyphaser A.

Chem Biodivers 2006 Dec;3(12):1301-6

Faculty of Pharmaceutical Science, Life Science Center and Center for Area Research and Development, Kobe Gakuin University, 518 Arise Ikawadani-cho, Nishi-ku, Kobe 651-2180, Japan.

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http://dx.doi.org/10.1002/cbdv.200690133DOI Listing
December 2006

Spontaneous membrane fusion induced by chemical formation of ceramides in a lipid bilayer.

J Am Chem Soc 2006 Nov;128(45):14452-3

Faculty of Pharmaceutical Sciences, Kobe Gakuin University, JST, Nishi-ku, Kobe 651-2180, Japan.

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http://dx.doi.org/10.1021/ja0652969DOI Listing
November 2006

Primary-amine-specific lactamization of omega-amino acids by an artificial cyclotransferase based on [18]crown-6.

Angew Chem Int Ed Engl 2006 Feb;45(8):1252-5

Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Nishi-ku, Kobe 651-2180, Japan.

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http://doi.wiley.com/10.1002/anie.200504027
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http://dx.doi.org/10.1002/anie.200504027DOI Listing
February 2006

Unusual rate enhancement of bimolecular dehydrocondensation to form amides at the interface of micelles of fatty acid salts.

Angew Chem Int Ed Engl 2005 Nov;44(44):7254-7

Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe 651-2180, Japan.

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http://dx.doi.org/10.1002/anie.200502594DOI Listing
November 2005

Development of novel polymer-type dehydrocondensing reagents comprised of chlorotriazines.

Chem Commun (Camb) 2005 Jun 7(21):2698-700. Epub 2005 Apr 7.

Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Nishi-ku, Kobe 651-2180, Japan.

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http://dx.doi.org/10.1039/b501917fDOI Listing
June 2005

Development of a simple system for dehydrocondensation using solid-phase adsorption of a water-soluble dehydrocondensing reagent (DMT-MM).

Chem Pharm Bull (Tokyo) 2004 Oct;52(10):1223-6

Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan.

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http://dx.doi.org/10.1248/cpb.52.1223DOI Listing
October 2004

Preparation of Weinreb amides using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM).

Chem Pharm Bull (Tokyo) 2004 Apr;52(4):470-2

Faculty of Pharmaceutical Sciences and High Technology Research Center, Kobe Gakuin University, Japan.

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http://dx.doi.org/10.1248/cpb.52.470DOI Listing
April 2004

A racemization test in peptide synthesis using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM).

Chem Pharm Bull (Tokyo) 2002 Apr;50(4):549-50

Faculty of Pharmaceutical Sciences and High Technology Research Center, Kobe Gakuin University, Japan.

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http://dx.doi.org/10.1248/cpb.50.549DOI Listing
April 2002