Muhammad Qasim, PhD Nano Bio Energy Engineering (Molecular Biology) - Chung Ang University Seoul Korea - Dr

Muhammad Qasim

PhD Nano Bio Energy Engineering (Molecular Biology)

Chung Ang University Seoul Korea

Dr

Seoul

Main Specialties: Biology, Biotechnology, Chemistry, Infectious Disease, Pharmacology, Public Health

Additional Specialties: Biomaterials, Molecular Biology, Infectious Diseases. Nanotechnology

ORCID logohttps://orcid.org/0000-0003-0279-5305


Top Author

Muhammad Qasim, PhD Nano Bio Energy Engineering (Molecular Biology) - Chung Ang University Seoul Korea - Dr

Muhammad Qasim

PhD Nano Bio Energy Engineering (Molecular Biology)

Introduction

Muhammad Qasim completed his PhD in Bio-engineering from Chung Ang University, South Korea and currently serving as Research Professor at Ajou University School of Medicine. His research work is concerned with nanomedicince, biomaterials, polymeric nanoparticles, nanogels and nanofibers for 3D cell culture and tissue engineering. Previously, he served in the Pakistan Atomic Energy Commission (PAEC), National AIDS Control program Pakistan (UNFPA), National TB Control Program Pakistan (GF UNO) and Quaid-i-Azam University Islamabad, Pakistan as a researcher. He also worked in collaboration with the Bioengagment Program (BEP) USA, Landu Network Centre Volta (LNCV, Italy), International Council for Life Sciences (ICLS) and American Association for Advancement of Sciences (AAAS, USA) for various projects of risk management, bioethics, biosafety, Biosecurity, dual use education and responsible conduct of sciences in Pakistan and Middle East region. He is a motivated young scientist and social activist. He is also serving as a Young Leader at CTBTO Youth (IAEA, Austria) and Young Leader at Pacific Forum CSIS (Center for Strategic and International Studies, USA). Moreover, he has responsibilities of the president of the Broader Middle East and North Africa Association of Young Scientist (BAYS). He is a member of many world advisory committees, forums and organisations working in science and technology domains. His areas of interest are International relation and regional security, science diplomacy, threat reduction of biological and chemical warfare, arms proliferation and disarmament, synthetic biology and dual use education, responsible conduct of sciences, energy, nanotechnology, tissue engineering, Nano Biomaterials, nanomedicine, youth leadership, entrepreneurship.

Primary Affiliation: Chung Ang University Seoul Korea - Seoul

Specialties:

Additional Specialties:


View Muhammad Qasim’s Resume / CV

Education

Mar 2012 - Feb 2015
Chung-Ang University
PhD
Nano Bio Energy Engineering

Experience

Jul 2015 - Aug 2016
Ajou University School of Medicine and Graduate School of Medicine
Research Professor
Pharmacy
Jan 2018
Konkuk University
Post Doc
Stem Cells and Regenerative Biotechnology

Publications

4Publications

34Reads

1153Profile Views

Nanoparticle-Mediated Combination Therapy: Two-in-One Approach for Cancer

Int. J. Mol. Sci. 2018, 19(10), 3264; https://doi.org/10.3390/ijms19103264

International Journal of Molecular Sciences

Cancer represents a group of heterogeneous diseases characterized by uncontrolled growth and spread of abnormal cells, ultimately leading to death. Nanomedicine plays a significant role in the development of nanodrugs, nanodevices, drug delivery systems and nanocarriers. Some of the major issues in the treatment of cancer are multidrug resistance (MDR), narrow therapeutic window and undesired side effects of available anticancer drugs and the limitations of anticancer drugs. Several nanosystems being utilized for detection, diagnosis and treatment such as theranostic carriers, liposomes, carbon nanotubes, quantum dots, polymeric micelles, dendrimers and metallic nanoparticles. However, nonbiodegradable nanoparticles causes high tissue accumulation and leads to toxicity. MDR is considered a major impediment to cancer treatment due to metastatic tumors that develop resistance to chemotherapy. MDR contributes to the failure of chemotherapies in various cancers, including breast, ovarian, lung, gastrointestinal and hematological malignancies. Moreover, the therapeutic efficiency of anticancer drugs or nanoparticles (NPs) used alone is less than that of the combination of NPs and anticancer drugs. Combination therapy has long been adopted as the standard first-line treatment of several malignancies to improve the clinical outcome. Combination therapy with anticancer drugs has been shown to generally induce synergistic drug actions and deter the onset of drug resistance. Therefore, this review is designed to report and analyze the recent progress made to address combination therapy using NPs and anticancer drugs. We first provide a comprehensive overview of the angiogenesis and of the different types of NPs currently used in treatments of cancer; those emphasized in this review are liposomes, polymeric NPs, polymeric micelles (PMs), dendrimers, carbon NPs, nanodiamond (ND), fullerenes, carbon nanotubes (CNTs), graphene oxide (GO), GO nanocomposites and metallic NPs used for combination therapy with various anticancer agents. Nanotechnology has provided the convenient tools for combination therapy. However, for clinical translation, we need continued improvements in the field of nanotechnology

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October 2018
6 Reads

Cytotoxic Potential and Molecular Pathway Analysis of Silver Nanoparticles in Human Colon Cancer Cells HCT116.

Int J Mol Sci 2018 Aug 2;19(8). Epub 2018 Aug 2.

Department of Stem Cell and Regenerative Biotechnology and Humanized Pig Center (SRC), Konkuk Institute of Technology, Konkuk University, Seoul 05029, Korea.

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http://dx.doi.org/10.3390/ijms19082269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121495PMC
August 2018
26 Reads
2.862 Impact Factor

Predictors of poor treatment outcomes in multidrug-resistant tuberculosis patients: a retrospective cohort study.

Clin Microbiol Infect 2018 Jun 29;24(6):612-617. Epub 2017 Sep 29.

Ajou University School of Medicine, Suwon, South Korea.

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http://dx.doi.org/10.1016/j.cmi.2017.09.012DOI Listing
June 2018
8 Reads
5.770 Impact Factor

Top co-authors

W Ahmad
W Ahmad

Quaid-i-Azam University

1
Chanhyeok Park
Chanhyeok Park

Konkuk Institute of Technology

1
Hyunjin Yoo
Hyunjin Yoo

Konkuk University

1
Jin-Hoi Kim
Jin-Hoi Kim

Animal Resources Research Center

1
Kwonho Hong
Kwonho Hong

Dankook University

1
Sangiliyandi Gurunathan
Sangiliyandi Gurunathan

Kalasalingam University

1