Muhammad Mamdani

Muhammad Mamdani

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Muhammad Mamdani

Muhammad Mamdani

Publications by authors named "Muhammad Mamdani"

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A concept analysis and overview of outcome measures used for evaluating patients with proximal humerus fractures.

Disabil Rehabil 2019 Sep 3:1-13. Epub 2019 Sep 3.

Institute of Medical Science, University of Toronto , Toronto , Canada.

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http://dx.doi.org/10.1080/09638288.2019.1649728DOI Listing
September 2019

The impact of randomized trial results on abdominal aortic aneurysm repair rates from 2003 to 2016: A population-based time-series analysis.

Vascular 2019 Aug 24;27(4):417-426. Epub 2019 Mar 24.

1 Division of Vascular Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1177/1708538119829582DOI Listing
August 2019

Characterizing the impact of snowfall on patient attendance at an urban emergency department in Toronto, Canada.

Am J Emerg Med 2019 Aug 31;37(8):1544-1546. Epub 2019 May 31.

Li Ka Shing Centre for Healthcare Analytics Research and Training (LKS-CHART), St. Michael's Hospital, Toronto, Canada; Department of Medicine, University of Toronto, Toronto, Canada; Department of Emergency Medicine, St. Michael's Hospital, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajem.2019.05.032DOI Listing
August 2019

Healthcare resource utilization and costs among patients with direct oral anticoagulant or warfarin-related major bleeding.

Thromb Res 2019 Aug 2;182:12-19. Epub 2019 Aug 2.

Health Services and Policy Research Institute, Queen's University, Kingston, Canada; Department of Public Health Sciences, Queen's University, Kingston, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2019.07.026DOI Listing
August 2019

AutoScribe: Extracting Clinically Pertinent Information from Patient-Clinician Dialogues.

Stud Health Technol Inform 2019 Aug;264:1512-1513

Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3233/SHTI190510DOI Listing
August 2019

Providing Data-Driven Equitable Palliative and End-of-Life Care for Structurally Vulnerable Populations: A Pilot Survey of Information Management Strategies.

Am J Hosp Palliat Care 2019 Aug 29:1049909119872756. Epub 2019 Aug 29.

2 Li Ka Shing-Centre for Healthcare Analytics, Research and Training, St Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1177/1049909119872756DOI Listing
August 2019

Preparing family medicine trainees for the information revolution: Pearls, potential, promise, and pitfalls.

Can Fam Physician 2019 Jun;65(6):390-392

Director of the Li Ka Shing Centre for Healthcare Analytics Research and Training in the Li Ka Shing Knowledge Institute at St Michael's Hospital in Toronto, Ont, and Professor in the Leslie Dan Faculty of Pharmacy, the Department of Medicine, and the Institute of Health Policy, Management and Evaluation of the Dalla Lana School of Public Health at the University of Toronto.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738380PMC
June 2019

Préparer les résidents en médecine familiale à la révolution de l’information: Perles, potentiel, promesses et pièges.

Can Fam Physician 2019 Jun;65(6):e240-e243

Directeur du Li Ka Shing Centre for Healthcare Analytics Research and Training au Li Ka Shing Knowledge Institute, à l'Hôpital St Michael's à Toronto (Ontario), et professeur à la Faculté Leslie Dan de pharmacie, au Département de médecine et à l'Institute of Health Policy, Management and Evaluation de la Faculté Dalla Lana de santé publique de l'Université de Toronto.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738375PMC
June 2019

Machine Learning in Medicine.

N Engl J Med 2019 06;380(26):2588-2589

Li Ka Shing Centre for Healthcare Analytics Research and Training, Toronto, ON, Canada

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http://dx.doi.org/10.1056/NEJMc1906060DOI Listing
June 2019

Impact of delisting high-strength opioid formulations from a public drug benefit formulary on opioid utilization in Ontario, Canada.

Pharmacoepidemiol Drug Saf 2019 May 14;28(5):726-733. Epub 2019 Mar 14.

Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pds.4764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518867PMC
May 2019

Temporal Trends of Women Enrollment in Major Cardiovascular Randomized Clinical Trials.

Can J Cardiol 2019 May 30;35(5):653-660. Epub 2019 Jan 30.

Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Terrence Donnelly Heart Centre, St. Michael's Hospital, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2019.01.010DOI Listing
May 2019

Trends in elective and ruptured abdominal aortic aneurysm repair by practice setting in Ontario, Canada, from 2003 to 2016: a population-based time-series analysis.

CMAJ Open 2019 Apr-Jun;7(2):E379-E384. Epub 2019 May 30.

Division of Vascular Surgery (Salata, Hussain, de Mestral, Greco, Aljabri, Sabongui, Al-Omran), Li Ka Shing Knowledge Institute of St. Michael's Hospital, and University of Toronto, Toronto, Ont.; Department of Surgery (Aljabri), King Saud University, Riyadh, Kingdom of Saudi Arabia; Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Leslie Dan Faculty of Pharmacy (Mamdani), University of Toronto; Division of Vascular Surgery (Forbes), Peter Munk Cardiac Centre, University Health Network, and University of Toronto, Toronto, Ont.; Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School (Bhatt), Boston, Mass.; Division of Cardiac Surgery (Verma), Li Ka Shing Knowledge Institute of St. Michael's Hospital, and University of Toronto, Toronto, Ont.

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http://dx.doi.org/10.9778/cmajo.20180173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544505PMC
May 2019

Linking Quality Improvement and Health Information Technology through the QI-HIT Figure 8.

Appl Clin Inform 2019 May 24;10(3):528-533. Epub 2019 Jul 24.

Centre for Quality Improvement and Patient Safety, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1055/s-0039-1693456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656570PMC
May 2019

Analysis of Trends in Insulin Utilization and Spending Across Canada From 2010 to 2015.

Can J Diabetes 2019 Apr 16;43(3):179-185.e1. Epub 2018 Aug 16.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada; Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jcjd.2018.08.190DOI Listing
April 2019

Evaluation of the fentanyl patch-for-patch program in Ontario, Canada.

Int J Drug Policy 2019 04 8;66:82-86. Epub 2019 Feb 8.

Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada; Institute for Clinical Evaluative Sciences, Toronto, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.drugpo.2019.01.025DOI Listing
April 2019

The Electronic Asthma Management System (eAMS) improves primary care asthma management.

Eur Respir J 2019 Apr 25;53(4). Epub 2019 Apr 25.

Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1183/13993003.02241-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482383PMC
April 2019

Tramadol and the risk of seizure: nested case-control study of US patients with employer-sponsored health benefits.

BMJ Open 2019 Mar 13;9(3):e026705. Epub 2019 Mar 13.

Clinical Pharmacology and Toxicology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/bmjopen-2018-026705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429854PMC
March 2019

Impact of a household-level deductible on prescription drug use among lower-income adults: a quasi-experimental study.

CMAJ Open 2019 Jan-Mar;7(1):E167-E173. Epub 2019 Mar 29.

Centre for Health Services and Policy Research (Law, Cheng, Worthington, McGrail, Chan, Laba), School of Population and Public Health, University of British Columbia, Vancouver, BC; Department of Medicine (Majumdar), University of Alberta, Edmonton, Alta.; Menzies Centre for Health Policy (Laba), Faculty of Medicine and Health, University of Sydney, Sydney, Australia; Centre for Clinical Epidemiology and Evaluation (Laba), University of British Columbia, Vancouver, BC; Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital, Toronto, Ont.

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http://dx.doi.org/10.9778/cmajo.20180198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440883PMC
March 2019

Palliative Care in the Twenty-First Century: Using Advanced Analytics to Uncloak Insights from Big Data.

J Palliat Med 2019 Feb;22(2):124-125

2 Li Ka Shing-Centre for Healthcare Analytics, Research and Training, St. Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1089/jpm.2018.0609DOI Listing
February 2019

Estimating the clinical cost of drug development for orphan versus non-orphan drugs.

Orphanet J Rare Dis 2019 01 10;14(1):12. Epub 2019 Jan 10.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1186/s13023-018-0990-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327525PMC
January 2019

Large care gaps in primary care management of asthma: a longitudinal practice audit.

BMJ Open 2019 01 29;9(1):e022506. Epub 2019 Jan 29.

The Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/bmjopen-2018-022506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352804PMC
January 2019

Second-generation anti-depressants and risk of new-onset seizures in the elderly.

Clin Toxicol (Phila) 2018 12 10;56(12):1179-1184. Epub 2018 Jul 10.

d The Institute for Clinical Evaluative Sciences , Toronto , Ontario , Canada.

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http://dx.doi.org/10.1080/15563650.2018.1483025DOI Listing
December 2018

Pregabalin and the Risk for Opioid-Related Death: A Nested Case-Control Study.

Ann Intern Med 2018 11 21;169(10):732-734. Epub 2018 Aug 21.

Institute for Clinical Evaluative Sciences, Sunnybrook Research Institute, and University of Toronto, Toronto, Ontario, Canada (D.N.J.).

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http://annals.org/article.aspx?doi=10.7326/M18-1136
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http://dx.doi.org/10.7326/M18-1136DOI Listing
November 2018

Comparing the contribution of prescribed opioids to opioid-related hospitalizations across Canada: A multi-jurisdictional cross-sectional study.

Drug Alcohol Depend 2018 10 31;191:86-90. Epub 2018 Jul 31.

Institute for Clinical Evaluative Sciences, 2075 Bayview Ave, Toronto, Ontario M4N 3M5, Canada; Department of Medicine at the University of Toronto, 1 King's College Circle, Medical Sciences Building, Toronto, Ontario M5S 1A8, Canada.

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http://dx.doi.org/10.1016/j.drugalcdep.2018.06.028DOI Listing
October 2018

Mortality in Puerto Rico after Hurricane Maria.

N Engl J Med 2018 Oct 25;379(17):e30. Epub 2018 Oct 25.

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http://dx.doi.org/10.1056/NEJMc1810872DOI Listing
October 2018

Interprovincial Variation of Psychotropic Prescriptions Dispensed to Older Canadian Adults.

Can Geriatr J 2018 Sep 30;21(3):269-273. Epub 2018 Sep 30.

Leslie Dan Faculty of Pharmacy, University of Toronto, ON, Canada.

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https://cgjonline.ca/index.php/cgj/article/view/307
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http://dx.doi.org/10.5770/cgj.21.307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136906PMC
September 2018

Validation of abdominal aortic aneurysm repair codes in Ontario administrative data.

Clin Invest Med 2018 09 30;41(3):E148-E155. Epub 2018 Sep 30.

Division of Vascular Surgery, Department of Surgery, University of Toronto, Toronto ON; Division of Vascular Surgery, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto ON.

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http://dx.doi.org/10.25011/cim.v41i3.30858DOI Listing
September 2018

Association between perioperative beta blocker use and cancer survival following surgical resection.

Eur J Surg Oncol 2018 08 17;44(8):1164-1169. Epub 2018 May 17.

Division of General Surgery, University of Ottawa, Ottawa, Canada; Ottawa Hospital Research Institute, Ottawa, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ejso.2018.05.012DOI Listing
August 2018

Usability of an Educational Intervention to Overcome Therapeutic Inertia in Multiple Sclerosis Care.

Front Neurol 2018 10;9:522. Epub 2018 Jul 10.

Healthcare Analytics Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fneur.2018.00522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048250PMC
July 2018

The Burden of Opioid-Related Mortality in the United States.

JAMA Netw Open 2018 06 1;1(2):e180217. Epub 2018 Jun 1.

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

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http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
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http://dx.doi.org/10.1001/jamanetworkopen.2018.0217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324425PMC
June 2018

Publicly Funded Oral Chronic Hepatitis B Treatment Patterns in Ontario over 16 Years: An Ecologic Study.

J Manag Care Spec Pharm 2018 May;24(5):464-468

1 Li Ka Shing Knowledge Institute, St. Michael's Hospital; Institute for Clinical Evaluative Sciences; and Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.18553/jmcp.2018.24.5.464DOI Listing
May 2018

A population-based study of the risk of osteoporosis and fracture with dutasteride and finasteride.

BMC Musculoskelet Disord 2018 May 22;19(1):160. Epub 2018 May 22.

University of Toronto, 410 Sherbourne Street, 4th Floor, Toronto, ON, M4X 1K2, Canada.

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http://dx.doi.org/10.1186/s12891-018-2076-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964967PMC
May 2018

Measuring the Burden of Opioid-related Mortality in Ontario, Canada.

J Addict Med 2018 Sep/Oct;12(5):418-419

Keenan Research Centre of the Li Ka Shing Knowledge Institute St. Michael's Hospital The Institute for Clinical Evaluative Sciences Toronto, Ontario, Canada The Institute for Clinical Evaluative Sciences Toronto, Ontario, Canada Keenan Research Centre of the Li Ka Shing Knowledge Institute St. Michael's Hospital The Institute for Clinical Evaluative Sciences Toronto, Ontario, Canada The Institute for Clinical Evaluative Sciences Toronto, Ontario, Canada The Institute for Clinical Evaluative Sciences The Sunnybrook Research Institute Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/ADM.0000000000000412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200374PMC
April 2018

Publicly funded overactive bladder drug treatment patterns in Ontario over 15 years: An ecological study.

Can Urol Assoc J 2018 Mar 22;12(3):E142-E145. Epub 2017 Dec 22.

Li Ka Shing Knowledge Institute, St. Michael's Hospital; Toronto, ON, Canada.

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http://dx.doi.org/10.5489/cuaj.4541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869040PMC
March 2018

Online social network response to studies on antidepressant use in pregnancy.

J Psychosom Res 2018 03 17;106:70-72. Epub 2018 Jan 17.

University of Toronto, Toronto, Ontario, Canada; St. Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jpsychores.2018.01.009DOI Listing
March 2018

Catastrophic drug coverage: utilization insights from the Ontario Trillium Drug Program.

CMAJ Open 2018 Mar;6(1):E132-E138

Affiliations: Li Ka Shing Knowledge Institute (Tadrous, Gomes), St. Michael's Hospital; Institute for Clinical Evaluative Sciences (Tadrous, Greaves, Martins, Mamdani, Juurlink, Gomes); Leslie Dan Faculty of Pharmacy (Tadrous, Mamdani, Gomes), University of Toronto; Institute of Health Policy, Management and Evaluation (Mamdani, Juurlink, Gomes), University of Toronto; Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont.

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http://dx.doi.org/10.9778/cmajo.20170132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878951PMC
March 2018

Association between operator specialty and outcomes after carotid artery revascularization.

J Vasc Surg 2018 02 18;67(2):478-489.e6. Epub 2017 Aug 18.

Division of Vascular Surgery, St. Michael's Hospital, Toronto, Ontario, Canada; Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada; Li Ka Shing Collaborative Research Program, King Saud University, Riyadh, Kingdom of Saudi Arabia; Department of Surgery, King Saud University, Riyadh, Kingdom of Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.jvs.2017.05.123DOI Listing
February 2018

Real-world health care utilization and effectiveness of omalizumab for the treatment of severe asthma.

Ann Allergy Asthma Immunol 2018 01 3;120(1):59-65.e2. Epub 2017 Oct 3.

Applied Health Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada; Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.anai.2017.08.016DOI Listing
January 2018

Laying the digital and analytical foundations for Canada's future health care system.

CMAJ 2018 01;190(1):E1-E2

Editorial Advisory Board member (Mamdani) CMAJ; Li Ka Shing Knowledge Institute (Mamdani, Laupacis), St. Michael's Hospital; Faculty of Medicine (Mamdani, Laupacis), University of Toronto; Institute of Health Policy, Management, and Evaluation (Mamdani, Laupacis), University of Toronto; Institute for Clinical Evaluative Sciences (Mamdani, Laupacis); Leslie Dan Faculty of Pharmacy (Mamdani), University of Toronto, Toronto, Ont.

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http://dx.doi.org/10.1503/cmaj.170955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760252PMC
January 2018

Health services research: a special focus.

CMAJ 2017 12;189(49):E1504

Deputy Editor (Patrick, Stanbrook); Editorial Advisory Board member (Mamdani); Department of Medicine (Stanbrook, Mamdani), University of Toronto; Li Ka Shing Knowledge Institute (Mamdani), St. Michael's Hospital; Institute for Clinical Evaluative Sciences (Stanbrook, Mamdani), Toronto, Ont.; Interim Editor-in-Chief (Kelsall).

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http://dx.doi.org/10.1503/cmaj.171389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718887PMC
December 2017

Patient characteristics, resource use and outcomes associated with general internal medicine hospital care: the General Medicine Inpatient Initiative (GEMINI) retrospective cohort study.

CMAJ Open 2017 Dec 13;5(4):E842-E849. Epub 2017 Dec 13.

Affiliations: Li Ka Shing Centre for Healthcare Analytics Research and Training (Verma, Mamdani), St. Michael's Hospital; Eliot Phillipson Clinician-Scientist Training Program (Verma), Department of Medicine, University of Toronto; Li Ka Shing Knowledge Institute (Guo, Dhalla, Hwang, Laupacis, Mamdani, Razak), St. Michael's Hospital; Department of Medicine (Kwan), Sinai Health System; Department of Medicine (Kwan, Lapointe-Shaw, Rawal, Razak, Tang, Weinerman), University of Toronto; Division of General Internal Medicine (Rawal), University Health Network; Institute for Better Health (Tang, Reid), Trillium Health Partners; Sunnybrook Health Sciences Centre (Weinerman); University Health Network, Sinai Health System (Cram), University of Toronto; Health Quality Ontario (Dhalla); Sunnybrook Health Sciences Centre (Shadowitz), University of Toronto; Bridgepoint Health (Upshur), University of Toronto, Toronto, Ont.; Harvard Center for Population and Development Studies (Razak), Cambridge, Mass.

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http://dx.doi.org/10.9778/cmajo.20170097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741428PMC
December 2017

Testosterone therapy in hypogonadal men: a systematic review and network meta-analysis.

BMJ Open 2017 Nov 16;7(11):e015284. Epub 2017 Nov 16.

Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1136/bmjopen-2016-015284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701987PMC
November 2017

Prior Authorization and Canadian Public Utilization of Direct-Acting Oral Anticoagulants.

Healthc Policy 2017 11;13(2):68-78

Leslie Dan Faculty of Pharmacy & Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749525PMC
November 2017

Lipophilic Statins and the Risk of Intracranial Hemorrhage Following Ischemic Stroke: A Population-Based Study.

Drug Saf 2017 10;40(10):887-893

Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s40264-017-0552-zDOI Listing
October 2017

Prevalence and characteristics of opioid-related deaths involving alcohol in Ontario, Canada.

Drug Alcohol Depend 2017 10 5;179:416-423. Epub 2017 Aug 5.

Department of Psychiatry, Academic Medical Center University of Amsterdam, Meibergdreef 9, 1105, AZ Amsterdam-Zuidoost, Netherlands.

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http://dx.doi.org/10.1016/j.drugalcdep.2017.07.008DOI Listing
October 2017

Temporal Trends in Use of Composite End Points in Major Cardiovascular Randomized Clinical Trials in Prominent Medical Journals.

Circ Cardiovasc Qual Outcomes 2017 Oct;10(10)

From the Terrence Donnelly Heart Centre, Department of Medicine, St Michael's Hospital (N.S.T., A.T.Y.), Applied Health Research Centre, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital (G.L.), Institute of Health Policy, Management and Evaluation (G.L., M.M., A.L.), The Leslie Dan Faculty of Pharmacy (M.M.), and Li Ka Shing Knowledge Institute, St Michael's Hospital (M.M., A.L.), University of Toronto, Canada; and Department of Medicine, St Mary's General Hospital, Kitchener, Canada (S.H.A.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.117.003753DOI Listing
October 2017

Effectiveness of a financial incentive to physicians for timely follow-up after hospital discharge: a population-based time series analysis.

CMAJ 2017 Oct;189(39):E1224-E1229

Department of Medicine (Lapointe-Shaw, Mamdani, Redelmeier, Bell), University of Toronto; Li Ka Shing Knowledge Institute (Mamdani), St. Michael's Hospital; Institute for Clinical Evaluative Sciences (Mamdani, Luo, Austin, Ivers, Redelmeier, Bell); Department of Family and Community Medicine (Ivers), University of Toronto; Sinai Health System (Bell); Women's College Hospital (Ivers), Toronto, Ont.

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http://dx.doi.org/10.1503/cmaj.170092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628034PMC
October 2017

Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case-control study.

PLoS Med 2017 Oct 3;14(10):e1002396. Epub 2017 Oct 3.

Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1371/journal.pmed.1002396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626029PMC
October 2017

Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study.

Drug Saf 2017 09;40(9):835-840

Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s40264-017-0539-9DOI Listing
September 2017

Pregabalin and heart failure: A population-based study.

Pharmacoepidemiol Drug Saf 2017 Sep 16;26(9):1087-1092. Epub 2017 Jun 16.

Department of Medicine, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/pds.4239DOI Listing
September 2017

Direct Oral Anticoagulant- or Warfarin-Related Major Bleeding: Characteristics, Reversal Strategies, and Outcomes From a Multicenter Observational Study.

Chest 2017 07 17;152(1):81-91. Epub 2017 Feb 17.

Centre for Health Services and Policy Research, Queen's University, Kingston, ON, Canada; Department of Public Health Sciences, Queen's University, Kingston, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2017.02.009DOI Listing
July 2017

Effect of High-Dose vs Standard-Dose Wintertime Vitamin D Supplementation on Viral Upper Respiratory Tract Infections in Young Healthy Children.

JAMA 2017 Jul;318(3):245-254

Department of Pediatrics, St Michael's Hospital, Pediatric Research, Toronto, Ontario, Canada2Pediatric Outcomes Research Team, Division of Pediatric Medicine, Department of Pediatrics, the Hospital for Sick Children, Toronto, Ontario, Canada3Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada4Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada8The La Ka Shing Knowledge Institute of St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jama.2017.8708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817430PMC
July 2017

Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study.

Drug Saf 2017 09;40(9):835-840

Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s40264-017-0539-9DOI Listing
September 2017

More Rigorous Study Needed Before Claiming No Harm of Blood Glucose Test Strip Limits for Patients Using Insulin-Reply.

JAMA Intern Med 2017 06;177(6):890-891

St Michael's Hospital, Applied Health Research Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamainternmed.2017.1089DOI Listing
June 2017

The Cardiovascular Safety of Dutasteride.

J Urol 2017 05 16;197(5):1309-1314. Epub 2016 Nov 16.

Department of Family and Community Medicine (SCS), University of Toronto, Toronto, Ontario, Canada; University of Toronto (JMP, MMM, DJ), Toronto, Ontario, Canada; Institute for Clinical Evaluative Sciences (EMM, JMP, MMM, DJ), Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute and Applied Health Research Centre, St. Michael's Hospital (MMM), Toronto, Ontario, Canada; Sunnybrook Research Institute (DJ), Toronto, Ontario, Canada; Department of Family Medicine, McMaster University (JMP), Hamilton, Ontario, Canada; Centre for Health Services and Policy Research, School of Population and Public Health, University of British Columbia (SCS, MRL), Vancouver, British Columbia, Canada; King Saud University (MMM), Riyadh, Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.11.082DOI Listing
May 2017

Impact of income-based deductibles on drug use and health care utilization among older adults.

CMAJ 2017 May;189(19):E690-E696

Centre for Health Services and Policy Research (Law, Cheng, Worthington, McGrail, Chan), School of Population and Public Health, University of British Columbia, Vancouver, BC; Li Ka Shing Centre for Health-care Analytics Research and Training (Mamdani), St. Michael's Hospital, Toronto, Ont.; Department of Medicine (Majumdar), University of Alberta, Edmonton, Alta.

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http://dx.doi.org/10.1503/cmaj.161119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433870PMC
May 2017

Self-Monitoring of Blood Glucose: Impact of Quantity Limits in Public Drug Formularies on Provincial Costs Across Canada.

Can J Diabetes 2017 Apr 15;41(2):138-142. Epub 2016 Dec 15.

Leslie Dan Faculty of Pharmacy at the University of Toronto, Toronto, Ontario, Canada; Department of Medicine and the Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada; The Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jcjd.2016.08.225DOI Listing
April 2017

Computerized Insulin Order Sets and Glycemic Control in Hospitalized Patients.

Am J Med 2017 Mar 4;130(3):366.e1-366.e6. Epub 2016 Nov 4.

Department of Medicine, Faculty of Medicine, University of Toronto, Ontario, Canada; St. Michaels' Hospital, Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada; Dalla Lana School of Public Health, University of Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2016.09.034DOI Listing
March 2017

Prevalence and Causes of Attrition Among Surgical Residents: A Systematic Review and Meta-analysis.

JAMA Surg 2017 03;152(3):265-272

Division of Vascular Surgery, St Michael's Hospital, Toronto, Ontario, Canada3Department of Surgery, University of Toronto, Toronto, Ontario, Canada4Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada8The King Saud University-Li Ka Shing Collaborative Research Program, King Saud University, Riyadh, Kingdom of Saudi Arabia11Department of Surgery, King Saud University, Riyadh, Kingdom of Saudi Arabia.

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http://dx.doi.org/10.1001/jamasurg.2016.4086DOI Listing
March 2017

Overdose Risk in Young Children of Women Prescribed Opioids.

Pediatrics 2017 Mar 20;139(3). Epub 2017 Feb 20.

The Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1542/peds.2016-2887DOI Listing
March 2017

Second-Generation Antidepressants and Hyponatremia Risk: A Population-Based Cohort Study of Older Adults.

Am J Kidney Dis 2017 Jan 20;69(1):87-96. Epub 2016 Oct 20.

Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada; Division of Nephrology, Department of Medicine, Western University, London, Ontario, Canada; Institute for Clinical Evaluative Sciences, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2016.08.020DOI Listing
January 2017

Association of a Blood Glucose Test Strip Quantity-Limit Policy With Patient Outcomes: A Population-Based Study.

JAMA Intern Med 2017 01;177(1):61-66

Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada2The Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ontario, Canada3Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada4Department of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada7Department of Medicine, University of Toronto, Toronto, Ontario, Canada10St Michael's Hospital, Toronto, Ontario, Canada.

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http://jamanetwork.com/data/Journals/INTEMED/935942/IOI16009
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http://dx.doi.org/10.1001/jamainternmed.2016.6851DOI Listing
January 2017

Association between statin use and ischemic stroke or major hemorrhage in patients taking dabigatran for atrial fibrillation.

CMAJ 2017 Jan 21;189(1):E4-E10. Epub 2016 Nov 21.

Department of Family and Community Medicine (Antoniou), St. Michael's Hospital and University of Toronto; Li Ka Shing Knowledge Institute (Gomes) and Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Leslie Dan Faculty of Pharmacy (Gomes, Tadrous, Mamdani) and Department of Medicine (Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (Antoniou, Macdonald, Yao, Hollands, Gomes, Tadrous, Mamdani, Juurlink); Applied Health Research Centre (Tadrous), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont.

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http://dx.doi.org/10.1503/cmaj.160303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224945PMC
January 2017

Impact of Clinical Trial Results on the Temporal Trends of Carotid Endarterectomy and Stenting From 2002 to 2014.

Stroke 2016 12 10;47(12):2923-2930. Epub 2016 Nov 10.

From the Divisions of Vascular Surgery (M.A.H., Z.K., B.A., M.A.-O.), Neurology (G.S.), and Cardiac Surgery (S.V.) and Li Ka Shing Knowledge Institute, St Michael's Hospital (M.M., G.S., S.V., M.A.-O.), Toronto, Canada; Departments of Surgery (M.A.H., S.V., M.A.-O.) and Medicine (J.V.T., G.S.), University of Toronto, Toronto, Canada; Institute of Health Policy, Management, and Evaluation (M.M., J.V.T., G.S.) and Leslie Dan Faculty of Pharmacy (M.M.), University of Toronto, Canada; King Saud University-Li Ka Shing Collaborative Research Program (M.M., B.A., S.V., M.A.-O.); Department of Surgery, Taibah University, Madinah, Kingdom of Saudi Arabia (Z.K.); Department of Surgery, King Saud University, Riyadh, Kingdom of Saudi Arabia (B.A., M.A.-O.); Institute for Clinical Evaluative Sciences (M.M., J.V.T., G.S.), Toronto, Canada; and Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Canada (J.V.T.).

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http://dx.doi.org/10.1161/STROKEAHA.116.014856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120767PMC
December 2016

Antiepileptic drugs and hyponatremia in older adults: Two population-based cohort studies.

Epilepsia 2016 12 29;57(12):2067-2079. Epub 2016 Nov 29.

Department of Epidemiology & Biostatistics, Western University, London, Ontario, Canada.

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http://doi.wiley.com/10.1111/epi.13593
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http://dx.doi.org/10.1111/epi.13593DOI Listing
December 2016

Hospital admissions for lower respiratory tract infections among infants in the Canadian Arctic: a cohort study.

CMAJ Open 2016 Oct-Dec;4(4):E615-E622. Epub 2016 Oct 17.

Li Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.

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http://cmajopen.ca/cgi/doi/10.9778/cmajo.20150051
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http://dx.doi.org/10.9778/cmajo.20150051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173479PMC
October 2016