Publications by authors named "Mubarak M Aldosari"

3 Publications

  • Page 1 of 1

Prevalence of Medically Resistant Epilepsy in Saudi Arabia.

Neuroepidemiology 2021 6;55(3):232-238. Epub 2021 May 6.

King Fahad University Hospital, Alkhobar, Saudi Arabia.

Objectives: The objective of this study was to evaluate the prevalence of medically resistant epilepsy (MRE) in our hospital and to compare the prevalence with that in other populations.

Methods: We retrospectively analyzed the data of patients who visited the epilepsy clinics at King Fahd University Hospital, Al-Khobar, Saudi Arabia between January 2017 and December 2018. This study included patients aged ≥14 years who had at least 2 unprovoked seizures 24 h apart. Patients who had provoked seizure(s), paroxysmal events, or syncope or had incomplete medical records were excluded. The definition and classification of the International League Against Epilepsy were used. Moreover, we searched the En-glish literature using PubMed and Google Scholar to compare the prevalence of MRE between our population and other populations.

Results: In total, 1,151 patients were screened, and 751 patients were included in the final analysis. Of the 751 patients, 229 (male: 56.3%, female: 43.7%; mean age: 32.07 years, and standard deviation, 12.2 years) had MRE, with a cumulative prevalence of 30%. The etiology was as follows: unknown, 63.3% (n = 145); structural, 31.9% (n = 73); genetic, 3.1% (n = 7); and infectious, 1.7% (n = 4). None of the patients had metabolic or immune-related etiologies.

Conclusion: The prevalence of MRE in our population (30%) is close to that in other populations (30-36.5%). Early identification of such patients is crucial to improve their management.
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http://dx.doi.org/10.1159/000515743DOI Listing
May 2021

Non-lesional eating epilepsy with temporo-insular onset: A stereo-EEG study.

Epilepsy Behav Rep 2020 1;14:100368. Epub 2020 May 1.

Epilepsy Program, Department of Clinical Neurological Sciences, Western University, London, Ontario, Canada.

Eating Epilepsy (EE) is a rare and often under-recognized form of reflex epilepsy, which manifests with seizures triggered during meals, with or without spontaneous seizures. The electro-clinical manifestations of EE are distinct with variable response to antiseizure drugs. We report the case of a 34-year-old man who was seen for a 4-year history of drug-resistant focal impaired awareness seizures associated with eating without a structural cause. Scalp video-EEG delineated a right temporal seizure focus with atypical features. Subsequent stereo-EEG revealed synchronized seizure onset from the right mesial temporal region and the right inferior insula. Resective surgery of the involved areas rendered this patient seizure-free with 3 years' follow-up. In non-lesional cases of drug-resistant EE, the epileptogenic zone can be large and deep, and therefore stereo-EEG was helpful in determining the seizure onset zone.
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http://dx.doi.org/10.1016/j.ebr.2020.100368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334470PMC
May 2020

Focal Cortical Dysplasia Type IIa Manifesting as Epilepsia Partialis Continua for 50 Years.

Can J Neurol Sci 2018 01 2;45(1):106-108. Epub 2017 Oct 2.

2Department of Pathology,Western UniversityLondon,Ontario,Canada.

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http://dx.doi.org/10.1017/cjn.2017.237DOI Listing
January 2018