Motoki Takaku

Motoki Takaku

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Motoki Takaku

Motoki Takaku

Publications by authors named "Motoki Takaku"

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Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.

Nat Commun 2019 May 2;10(1):2079. Epub 2019 May 2.

CHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.

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http://dx.doi.org/10.1038/s41467-019-10161-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497626PMC
May 2019

Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.

Nat Commun 2019 02 15;10(1):883. Epub 2019 Feb 15.

CHU Sainte-Justine Research Center, Montreal, QC, H3T 1C5, Canada.

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http://dx.doi.org/10.1038/s41467-019-08800-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377600PMC
February 2019

CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.

Nat Commun 2018 11 5;9(1):4619. Epub 2018 Nov 5.

CHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.

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http://www.nature.com/articles/s41467-018-06014-6
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http://dx.doi.org/10.1038/s41467-018-06014-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218476PMC
November 2018

GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network.

Nat Commun 2018 03 13;9(1):1059. Epub 2018 Mar 13.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC, 27709, USA.

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http://www.nature.com/articles/s41467-018-03478-4
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http://dx.doi.org/10.1038/s41467-018-03478-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849768PMC
March 2018

Rif1 promotes a repressive chromatin state to safeguard against endogenous retrovirus activation.

Nucleic Acids Res 2017 Dec;45(22):12723-12738

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, RTP, NC 27709, USA.

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http://dx.doi.org/10.1093/nar/gkx884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727408PMC
December 2017

Reversing SKI-SMAD4-mediated suppression is essential for T17 cell differentiation.

Nature 2017 11 25;551(7678):105-109. Epub 2017 Oct 25.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1038/nature24283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743442PMC
November 2017

Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing.

Sci Rep 2016 Apr 7;6:24228. Epub 2016 Apr 7.

Laboratory of Structural Biology, Graduate School of Advanced Science &Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan.

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http://dx.doi.org/10.1038/srep24228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823753PMC
April 2016

High-quality ChIP-seq analysis of MBD3 in human breast cancer cells.

Genom Data 2016 Mar 6;7:173-4. Epub 2016 Jan 6.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, USA.

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http://dx.doi.org/10.1016/j.gdata.2015.12.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778645PMC
March 2016

GATA3 in Breast Cancer: Tumor Suppressor or Oncogene?

Gene Expr 2015 ;16(4):163-8

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Science, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.3727/105221615X14399878166113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758516PMC
February 2016

Relaxed Chromatin Formation and Weak Suppression of Homologous Pairing by the Testis-Specific Linker Histone H1T.

Biochemistry 2016 Feb 22;55(4):637-46. Epub 2016 Jan 22.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University , 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan.

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http://dx.doi.org/10.1021/acs.biochem.5b01126DOI Listing
February 2016

GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler.

Genome Biol 2016 Feb 27;17:36. Epub 2016 Feb 27.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1186/s13059-016-0897-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769547PMC
February 2016

Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover.

BMC Cancer 2014 Apr 22;14:278. Epub 2014 Apr 22.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, 111 T,W, Alexander Dr, 27709 Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1186/1471-2407-14-278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021073PMC
April 2014

Vertebrate Spt2 is a novel nucleolar histone chaperone that assists in ribosomal DNA transcription.

J Cell Sci 2013 Mar 1;126(Pt 6):1323-32. Epub 2013 Feb 1.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan.

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http://dx.doi.org/10.1242/jcs.112623DOI Listing
March 2013

Human PSF concentrates DNA and stimulates duplex capture in DMC1-mediated homologous pairing.

Nucleic Acids Res 2012 Apr 9;40(7):3031-41. Epub 2011 Dec 9.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan.

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http://dx.doi.org/10.1093/nar/gkr1229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326331PMC
April 2012

Purification of the human SMN-GEMIN2 complex and assessment of its stimulation of RAD51-mediated DNA recombination reactions.

Biochemistry 2011 Aug 25;50(32):6797-805. Epub 2011 Jul 25.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan.

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http://pubs.acs.org/doi/abs/10.1021/bi200828g
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http://dx.doi.org/10.1021/bi200828gDOI Listing
August 2011

Biochemical analysis of the human ENA/VASP-family proteins, MENA, VASP and EVL, in homologous recombination.

J Biochem 2011 Jun 11;149(6):721-9. Epub 2011 Mar 11.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1093/jb/mvr029DOI Listing
June 2011

Halenaquinone, a chemical compound that specifically inhibits the secondary DNA binding of RAD51.

Genes Cells 2011 Apr 6;16(4):427-36. Epub 2011 Mar 6.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, Shinjuku-ku, Tokyo 162-8480, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2011.01494.xDOI Listing
April 2011

Single-stranded DNA catenation mediated by human EVL and a type I topoisomerase.

Nucleic Acids Res 2010 Nov 17;38(21):7579-86. Epub 2010 Jul 17.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkq630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995056PMC
November 2010

GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination.

Nucleic Acids Res 2010 Aug 19;38(15):5059-74. Epub 2010 Apr 19.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.

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http://dx.doi.org/10.1093/nar/gkq271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926616PMC
August 2010

Holliday junction-binding activity of human SPF45.

Genes Cells 2010 Apr 4;15(4):373-83. Epub 2010 Mar 4.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2010.01383.xDOI Listing
April 2010

Biochemical analysis of the human EVL domains in homologous recombination.

FEBS J 2009 Oct 2;276(20):5841-8. Epub 2009 Sep 2.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1742-4658.2009.07265.xDOI Listing
October 2009

The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction.

Nucleic Acids Res 2009 Jul 29;37(12):3959-68. Epub 2009 Apr 29.

Laboratory of Molecular Radiology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1093/nar/gkp262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709562PMC
July 2009

Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities.

Nucleic Acids Res 2009 Jul 15;37(13):4296-307. Epub 2009 May 15.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo 162-8480, Japan.

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http://dx.doi.org/10.1093/nar/gkp298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715225PMC
July 2009

Recombination activator function of the novel RAD51- and RAD51B-binding protein, human EVL.

J Biol Chem 2009 May 26;284(21):14326-36. Epub 2009 Mar 26.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, and Consolidated Research Institute for Advanced Science and Medical Care, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan.

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http://dx.doi.org/10.1074/jbc.M807715200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682881PMC
May 2009