Moses Rodriguez

Moses Rodriguez

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Moses Rodriguez

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IgM Natural Autoantibodies in Physiology and the Treatment of Disease.

Methods Mol Biol 2019 ;1904:53-81

Department of Neurology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/978-1-4939-8958-4_3DOI Listing
June 2019

Optimization of a 40-mer Antimyelin DNA Aptamer Identifies a 20-mer with Enhanced Properties for Potential Multiple Sclerosis Therapy.

Nucleic Acid Ther 2019 Jun 11;29(3):126-135. Epub 2019 Mar 11.

1 Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.

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https://www.liebertpub.com/doi/10.1089/nat.2018.0776
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http://dx.doi.org/10.1089/nat.2018.0776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555174PMC
June 2019

Glial cells as therapeutic targets in progressive multiple sclerosis.

Expert Rev Neurother 2019 Jun 13;19(6):481-494. Epub 2019 May 13.

b Departments of Neurology and Immunology , Mayo Clinic College of Medicine and Science , Rochester , MN , USA.

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https://www.tandfonline.com/doi/full/10.1080/14737175.2019.1
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http://dx.doi.org/10.1080/14737175.2019.1614443DOI Listing
June 2019

Acute vision loss in multiple sclerosis: Optic neuritis or central serous chorioretinopathy?

Mult Scler Relat Disord 2019 01 2;27:147-150. Epub 2018 Oct 2.

Isfahan Eye Research Center (IERC), Feiz Hospital, Isfahan University of Medical Sciences, Isfahan, Iran; Department of Ophthalmology, Feiz Hospital, Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Research Committee of Multiple Sclerosis (IRCOMS), Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Medical Students Research Center (IMSRC), Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22110348183035
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http://dx.doi.org/10.1016/j.msard.2018.09.034DOI Listing
January 2019

Surface Plasmon Resonance Sensing on Naturally Derived Membranes: A Remyelination-Promoting Human Antibody Binds Myelin with Extraordinary Affinity.

Anal Chem 2018 11 15;90(21):12567-12573. Epub 2018 Oct 15.

Department of Electrical and Computer Engineering , University of Minnesota , Minneapolis , Minnesota 55455 , United States.

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http://dx.doi.org/10.1021/acs.analchem.8b02664DOI Listing
November 2018

Use of newer disease-modifying therapies in pediatric multiple sclerosis in the US.

Neurology 2018 11 17;91(19):e1778-e1787. Epub 2018 Oct 17.

From the Department of Neurology (K.M.K., J.G., E.W.), University of California San Francisco; Department of Neurology (M. Rensel), Cleveland Clinic, OH; Department of Neurology (B.W.-G.), State University of New York at Buffalo; Department of Pediatrics (G.A.), Loma Linda University, CA; Department of Neurology (L.B., M. Gorman), Boston Children's Hospital, MA; Department of Neurology (T.C.), Massachusetts General Hospital, Boston; Department of Neurology (M. Goyal, S.M.), Washington University in Saint Louis, MO; Department of Neurology (L.K.), New York University Langone Medical Center, NY; Department of Neurology (T.L.), Texas Children's Hospital, Houston; Department of Neurology (M. Rodriguez), Mayo Clinic, Rochester, MN; and Department of Neurology (J.R.), Biostatistician II (M.W.), and Department of Pediatrics (T.C.C.), University of Utah, Salt Lake City.

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http://dx.doi.org/10.1212/WNL.0000000000006471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251604PMC
November 2018

Age is a critical determinant in recovery from multiple sclerosis relapses.

Mult Scler 2018 Oct 10:1352458518800815. Epub 2018 Oct 10.

Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology, and Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://journals.sagepub.com/doi/10.1177/1352458518800815
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http://dx.doi.org/10.1177/1352458518800815DOI Listing
October 2018

An Assay that Predicts Efficacy for DNA Aptamers that Stimulate Remyelination in a Mouse Model of Multiple Sclerosis.

Mol Ther Methods Clin Dev 2018 Jun 21;9:270-277. Epub 2018 Mar 21.

Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.omtm.2018.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918178PMC
June 2018

A comparison of human natural monoclonal antibodies and aptamer conjugates for promotion of CNS remyelination: where are we now and what comes next?

Expert Opin Biol Ther 2018 05 25;18(5):545-560. Epub 2018 Feb 25.

a Department of Neurology , Mayo Clinic College of Medicine and Science , Rochester , MN , USA.

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http://dx.doi.org/10.1080/14712598.2018.1441284DOI Listing
May 2018

Multiple Sclerosis: Mechanisms of Disease and Strategies for Myelin and Axonal Repair.

Neurol Clin 2018 Feb;36(1):1-11

Department of Neurology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.ncl.2017.08.002DOI Listing
February 2018

Demyelination with preferential MAG loss: A complex message from MS paraffin blocks.

J Neurol Sci 2018 02 24;385:126-130. Epub 2017 Dec 24.

Department of Neurology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2017.12.029DOI Listing
February 2018

Multiple Sclerosis, Gut Microbiota and Permeability: Role of Tryptophan Catabolites, Depression and the Driving Down of Local Melatonin.

Curr Pharm Des 2016 ;22(40):6134-6141

Guggenheim 4-42B, 200 1st Street SW, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.2174/1381612822666160915160520DOI Listing
December 2017

Timing of Future Remyelination Therapies and Their Potential to Stop Multiple Sclerosis Progression.

Adv Exp Med Biol 2017 ;958:161-170

Department of Neurology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/978-3-319-47861-6_10DOI Listing
September 2017

The Spectrum of Inflammatory Acquired Demyelinating Syndromes in Children.

Semin Pediatr Neurol 2017 08 23;24(3):189-200. Epub 2017 Aug 23.

Department of Pediatric Neurology, Sick Kids Children's Hospital, Toronto, Canada.

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http://dx.doi.org/10.1016/j.spen.2017.08.007DOI Listing
August 2017

Sublethal oligodendrocyte injury: A reversible condition in multiple sclerosis?

Ann Neurol 2017 Jun 2;81(6):811-824. Epub 2017 Jun 2.

Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/ana.24944DOI Listing
June 2017

Biomarkers in radiologically isolated syndrome: The missing piece in the puzzle of treatment indication?

J Neurol Sci 2017 04 18;375:129. Epub 2017 Jan 18.

Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.jns.2017.01.055DOI Listing
April 2017

Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS.

Neurology 2017 Apr 29;88(17):1623-1629. Epub 2017 Mar 29.

From the Division of Epidemiology, School of Public Health (M.A.G., X.S., E.X., H.Q., D.Q., C.M., L.F.B.), and Computational Biology Graduate Group (B.R.), University of California, Berkeley; Department of Clinical Neuroscience and Center for Molecular Medicine (P.S.), Karolinska Institutet at Karolinska University Hospital, Stockholm, Sweden; Department of Neurology (J.S.G., E.W.) and Regional Pediatric MS Center, Neurology (J.H., S.C.), University of California, San Francisco; Partners Pediatric Multiple Sclerosis Center (T.C.), Massachusetts General Hospital for Children, Boston; Division of Neurology (A.W.), Children's Hospital of Philadelphia, PA; Blue Bird Circle Multiple Sclerosis Center (T.L.), Baylor College of Medicine, Houston, TX; Children's Hospital Colorado (T.S.), University of Colorado, Denver; Lourie Center for Pediatric Multiple Sclerosis (A.B., L.K.), Stony Brook Children's Hospital, NY; Department of Neurology (B.G.), University of Texas Southwestern, Dallas; Pediatric Multiple Sclerosis Center (B.W.-G.), Jacobs Neurological Institute, SUNY Buffalo, NY; Pediatric MS Center at Loma Linda University Children's Hospital (G.A.), CA; Mayo Clinic's Pediatric Multiple Sclerosis Center (J.M.T., M.R.), Rochester, MN; University of Alabama Center for Pediatric-onset Demyelinating Disease (J.N., Y.H.), Children's Hospital of Alabama, Birmingham; Department of Pediatric Neurology (J.R.), Northwestern Feinberg School of Medicine, Chicago, IL; Primary Children's Hospital (M.C.), University of Utah, Salt Lake City; Boston Children's Hospital (M.G., L.B.), MA; Pediatric-onset Demyelinating Diseases and Autoimmune Encephalitis Center (S.M.), St. Louis Children's Hospital, Washington University School of Medicine, MO; Children's National Medical Center (I.K.), Washington, DC; Departments of Neurology (J.R.) and Pediatrics (S.R., T.C.C.), University of Utah School of Medicine, Salt Lake City; Kaiser Permanente Division of Research (L.S., C.S., L.F.B.), Oakland, CA; Institute of Environmental Medicine (J.H., M.B., A.H., T.O., I.K., L.A.), Karolinska Institutet; Centre for Occupational and Environmental Medicine (L.A.), Stockholm County Council, Stockholm, Sweden; and Research Program on Genes, Environment and Health (C.S.), Kaiser Permanente, Oakland, CA.

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http://dx.doi.org/10.1212/WNL.0000000000003849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405763PMC
April 2017

Tryptophan Catabolites and Their Impact on Multiple Sclerosis Progression.

Curr Pharm Des 2016 ;22(8):1049-59

Departments of Neurology and Immunology, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, Minnesota 55905, USA.

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December 2016

Distinct effects of obesity and puberty on risk and age at onset of pediatric MS.

Ann Clin Transl Neurol 2016 12 4;3(12):897-907. Epub 2016 Nov 4.

Department of Neurology University of California San Francisco California; Department of Pediatrics Benioff Children's Hospital University of California San Francisco California.

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http://dx.doi.org/10.1002/acn3.365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224818PMC
December 2016

Antibody-Mediated Oligodendrocyte Remyelination Promotes Axon Health in Progressive Demyelinating Disease.

Mol Neurobiol 2016 10 26;53(8):5217-28. Epub 2015 Sep 26.

Departments of Neurology, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s12035-015-9436-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012151PMC
October 2016

Concomitant Use of Neuroprotective Drugs in Neuro Rehabilitation of Multiple Sclerosis.

Int J Phys Med Rehabil 2016 Aug 23;4(4). Epub 2016 Jun 23.

Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA; Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.4172/2329-9096.1000348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006625PMC
August 2016

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study.

J Vis Exp 2016 06 29(112). Epub 2016 Jun 29.

Department of Neurology, Mayo Clinic; Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic; Center for Regenerative Medicine, Neuroregeneration, Mayo Clinic;

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http://dx.doi.org/10.3791/54139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993309PMC
June 2016

A monoclonal natural human IgM protects axons in the absence of remyelination.

J Neuroinflammation 2016 Apr 28;13(1):94. Epub 2016 Apr 28.

Department of Neurology, Mayo Clinic College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1186/s12974-016-0561-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850699PMC
April 2016

Clinical features of neuromyelitis optica in children: US Network of Pediatric MS Centers report.

Neurology 2016 Jan 18;86(3):245-52. Epub 2015 Dec 18.

From Partners Multiple Sclerosis Center (T.C.), Department of Neurology, Brigham and Women's Hospital, Brookline; Partners Pediatric Multiple Sclerosis Center (T.C.), Massachusetts General Hospital for Children, Boston; University of Alabama Center for Pediatric Onset Demyelinating Disease (J.N.), Children's Hospital of Alabama, Birmingham; the Lourie Center for Pediatric MS, Stony Brook Children's Hospital (L.K., A.B.), New York, NY; the Department of Neurology (E.W., J.G.) and the Department of Pediatrics, Benioff Children's Hospital (E.W.), University of California, San Francisco; the Departments of Pediatrics (T.H., C.S.O., T.C.C.) and Neurology (J.W.R.), University of Utah, Salt Lake City; Mayo Clinic's Pediatric MS Center (M.R., M.P.), Rochester, MN; Blue Bird Circle Multiple Sclerosis Center (T.L.), Baylor College of Medicine, Houston, TX; Boston Children's Hospital (M.G., L.B.), MA; the Pediatric Multiple Sclerosis Center (B.W.-G.), Jacobs Neurological Institute, SUNY Buffalo, New York, NY; and Pediatric MS Center at Loma Linda University Children's Hospital (G.A.), CA.

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http://www.neurology.org/content/early/2015/12/18/WNL.000000
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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000228
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http://dx.doi.org/10.1212/WNL.0000000000002283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733158PMC
January 2016

Tryptophan Metabolites and Their Impact on Multiple Sclerosis Progression.

Curr Pharm Des 2015 Dec 14. Epub 2015 Dec 14.

Departments of Neurology and Immunology, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, Minnesota 55905, U.S.A.

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December 2015

Naturally Occurring Monoclonal Antibodies and Their Therapeutic Potential for Neurologic Diseases.

JAMA Neurol 2015 Nov;72(11):1346-53

Department of Neurology, Mayo Clinic, Rochester, Minnesota2Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, Rochester, Minnesota5Department of Immunology, Mayo Clinic, Rochester, Minnesota.

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http://archneur.jamanetwork.com/data/Journals/NEUR/934619/nr
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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2015.2188DOI Listing
November 2015

Poor early relapse recovery affects onset of progressive disease course in multiple sclerosis.

Neurology 2015 Aug 24;85(8):722-9. Epub 2015 Jul 24.

From the Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology (M.N., M.M.P.S., B.M.K., I.P., S.J.P., C.F.L., J.H.N., B.G.W., M.R., O.H.K.), Department of Neurology, and Division of Biomedical Statistics & Informatics (D.J.C., E.J.A.), Mayo Clinic College of Medicine, Rochester, MN; International Clinical Research Center (M.N.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Neurology (N.A.Z.), Wake Forest Medical Center, Winston-Salem, NC; Department of Neurology (N.K.), Bakirkoy State Hospital, Istanbul, Turkey; and Department of Neurology (M.T., A.S.), Cerrahpasa School of Medicine, Istanbul University, Turkey.

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http://dx.doi.org/10.1212/WNL.0000000000001856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553030PMC
August 2015

A human anti-polysialic acid antibody as a potential treatment to improve function in multiple sclerosis patients.

J Nat Sci 2015 Aug;1(8)

Department of Neurology, Clinic College of Medicine, Rochester, Minnesota, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951103PMC
August 2015

Ebola virus: melatonin as a readily available treatment option.

J Med Virol 2015 Apr 21;87(4):537-43. Epub 2015 Jan 21.

CRC Scotland and London, Eccleston Square, London, United Kingdom.

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http://dx.doi.org/10.1002/jmv.24130DOI Listing
April 2015

Multiple sclerosis: the role of melatonin and N-acetylserotonin.

Mult Scler Relat Disord 2015 Mar 16;4(2):112-23. Epub 2014 Dec 16.

Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.msard.2014.12.001DOI Listing
March 2015

Quantitative PCR analysis of DNA aptamer pharmacokinetics in mice.

Nucleic Acid Ther 2015 Feb 23;25(1):11-9. Epub 2014 Dec 23.

1 Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine , Rochester, Minnesota.

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http://dx.doi.org/10.1089/nat.2014.0515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296750PMC
February 2015

Relapses and disability accumulation in progressive multiple sclerosis.

Neurology 2015 Jan 14;84(1):81-8. Epub 2014 Nov 14.

From the Mayo Clinic Center for Multiple Sclerosis and CNS Demyelinating Diseases, Department of Neurology (M.M.P.S., M.N., B.M.K., I.P., S.J.P., C.F.L., B.G.W., M.R., O.H.K.), and Division of Biomedical Statistics & Informatics (D.J.C., E.J.A.), Mayo Clinic College of Medicine, Rochester, MN; International Clinical Research Center (M.N.), St. Anne's University Hospital Brno, Czech Republic; Department of Neurology (N.A.Z.), American University of Beirut Medical Center, Lebanon; Department of Neurology (N.K.), Bakirkoy State Hospital, Istanbul; and Department of Neurology (M.T., A.S.), Cerrahpasa School of Medicine, Istanbul University, Turkey. N.A.Z., N.K., and M.T. were previous fellows of the Department of Neurology, Mayo Clinic College of Medicine.

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http://dx.doi.org/10.1212/WNL.0000000000001094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336097PMC
January 2015

Human-derived natural antibodies: biomarkers and potential therapeutics.

Future Neurol 2015;10(1):25-39

Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA ; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.2217/fnl.14.62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321763PMC
January 2015

Protective environmental factors for neuromyelitis optica.

Neurology 2014 Nov 22;83(21):1923-9. Epub 2014 Oct 22.

From the Department of Neurology (J.G., K.W., E.W.), University of California, San Francisco; Virginia Commonwealth Medical School (S.G.); Lourie Center for Pediatric MS (L.K., A.B.), Stony Brook Children's Hospital, NY; Partners MS Center (T.C.), Massachusetts General Hospital for Children, Harvard Medical School; UAB Center for Pediatric Onset Demyelinating Disease (J.N.), Children's Hospital of Alabama; Pediatric Multiple Sclerosis Center (B.W.-G.), Jacobs Neurological Institute, SUNY Buffalo, NY; Pediatric Multiple Sclerosis and Related Diseases Program (M.G.), Boston Children's Hospital, MA; Mayo Clinic's Pediatric MS Center (M.P., M.R.), Rochester, MN; Blue Bird Circle Multiple Sclerosis Center (T.L.), Texas Children's Hospital, Houston; Pediatric MS Center at Loma Linda University Children's Hospital (G.A.), CA; Multiple Sclerosis Center (E.M.M.), Johns Hopkins University, Baltimore, MD; Department of Pediatrics (J.W.R., T.S., T.C.C.), University of Utah, Salt Lake City; Oklahoma Medical Research Foundation (J.J.), Oklahoma City; and Department of Pediatrics (E.W.), UCSF Benioff Children's Hospital.

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http://dx.doi.org/10.1212/WNL.0000000000001001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248458PMC
November 2014

Formation of biomembrane microarrays with a squeegee-based assembly method.

J Vis Exp 2014 May 8(87). Epub 2014 May 8.

Department of Electrical and Computer Engineering, University of Minnesota; Department of Biomedical Engineering, University of Minnesota.

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http://dx.doi.org/10.3791/51501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032179PMC
May 2014

Polyclonal and monoclonal antibodies in clinic.

Methods Mol Biol 2014 ;1060:79-110

Departments of Neurology and Immunology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/978-1-62703-586-6_5DOI Listing
March 2014

Deletion of Virus-specific T-cells Enhances Remyelination in a Model of Multiple Sclerosis.

J Neurol Transl Neurosci 2014 Jan;2(1)

Department of Immunology, Mayo Clinic, Rochester, MN 55905.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222056PMC
January 2014

CD8(+) T cells in multiple sclerosis.

Expert Opin Ther Targets 2013 Sep 6;17(9):1053-66. Epub 2013 Jul 6.

Department of Neurology, Mayo Clinic, Rochester, MN 55905 , USA.

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http://dx.doi.org/10.1517/14728222.2013.815726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928018PMC
September 2013

Cellular targets and mechanistic strategies of remyelination-promoting IgMs as part of the naturally occurring autoantibody repertoire.

Expert Rev Neurother 2013 Sep;13(9):1017-29

Departments of Neurology and Immunology, Mayo Clinic, College of Medicine, 200 First Street, S.W., Rochester, MN 55905, USA.

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http://dx.doi.org/10.1586/14737175.2013.835601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909667PMC
September 2013

PDGF is required for remyelination-promoting IgM stimulation of oligodendrocyte progenitor cell proliferation.

PLoS One 2013 1;8(2):e55149. Epub 2013 Feb 1.

Departments of Neurology and Immunology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055149PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562326PMC
July 2013

The road to remyelination in demyelinating diseases: current status and prospects for clinical treatment.

Expert Rev Clin Immunol 2013 Jun;9(6):535-49

Department of Neurology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1586/eci.13.37DOI Listing
June 2013

Remyelination induced by a DNA aptamer in a mouse model of multiple sclerosis.

PLoS One 2012 27;7(6):e39595. Epub 2012 Jun 27.

Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039595PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384608PMC
March 2013

Onset of progressive phase is an age-dependent clinical milestone in multiple sclerosis.

Mult Scler 2013 Feb 26;19(2):188-98. Epub 2012 Jun 26.

Mayo Clinic Center for Multiple Sclerosis and CNS Demyelinating Diseases, Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1177/1352458512451510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029334PMC
February 2013

Naturally occurring antibodies as therapeutics for neurologic disease: can human monoclonal IgMs replace the limited resource IVIG?

Adv Exp Med Biol 2012 ;750:44-55

Department of Neurology and Immunology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1007/978-1-4614-3461-0_4DOI Listing
October 2012

Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis.

Brain Pathol 2012 Sep 21;22(5):709-22. Epub 2012 Mar 21.

Neurobiology of Disease Program, Mayo Medical and Graduate School, Rochester, MN, USA.

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http://dx.doi.org/10.1111/j.1750-3639.2012.00577.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360139PMC
September 2012

Is multiple sclerosis an autoimmune disease?

Autoimmune Dis 2012 16;2012:969657. Epub 2012 May 16.

Departments of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1155/2012/969657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361990PMC
August 2012

High-affinity binding of remyelinating natural autoantibodies to myelin-mimicking lipid bilayers revealed by nanohole surface plasmon resonance.

Anal Chem 2012 Jul 3;84(14):6031-9. Epub 2012 Jul 3.

Laboratory of Nanostructures and Biosensing, Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.

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http://pubs.acs.org/doi/10.1021/ac300819a
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http://dx.doi.org/10.1021/ac300819aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417152PMC
July 2012

Preclinical (1)H-MRS neurochemical profiling in neurological and psychiatric disorders.

Bioanalysis 2012 Jul;4(14):1787-804

Department of Biochemistry, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.4155/bio.12.129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922617PMC
July 2012

Need for a paradigm shift in therapeutic approaches to CNS injury.

Expert Rev Neurother 2012 Apr;12(4):409-20

Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1586/ern.12.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568973PMC
April 2012

Statin therapy and multiple sclerosis disability in a population-based cohort.

Mult Scler 2012 Mar 9;18(3):358-63. Epub 2011 Sep 9.

Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1177/1352458511421920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237737PMC
March 2012

Evidence for the role of B cells and immunoglobulins in the pathogenesis of multiple sclerosis.

Neurol Res Int 2011 22;2011:780712. Epub 2011 Sep 22.

Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1155/2011/780712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179868PMC
November 2011

A human IgM signals axon outgrowth: coupling lipid raft to microtubules.

J Neurochem 2011 Oct 1;119(1):100-12. Epub 2011 Sep 1.

Department of Neurology, Mayo Clinic and Foundation, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07416.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171625PMC
October 2011

Autoantibodies with enzymatic properties in human autoimmune diseases.

J Autoimmun 2011 Sep 31;37(2):144-50. Epub 2011 May 31.

Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.jaut.2011.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173522PMC
September 2011

Facile assembly of micro- and nanoarrays for sensing with natural cell membranes.

ACS Nano 2011 Sep 17;5(9):7555-64. Epub 2011 Aug 17.

Laboratory of Nanostructures and Biosensing, Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1021/nn202554tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183111PMC
September 2011

Pediatric multiple sclerosis.

Neurol Clin 2011 May;29(2):481-505

Harvard Medical School, Partners Pediatric Multiple Sclerosis Center, Massachusetts General Hospital for Children, 55 Fruit Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.ncl.2011.01.004DOI Listing
May 2011