Morris Kletzel

Morris Kletzel

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Morris Kletzel

Morris Kletzel

Publications by authors named "Morris Kletzel"

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High-dose chemotherapy and autologous hematopoietic stem-cell rescue for treatment of relapsed and refractory Wilms tumor: Re-evaluating outcomes.

Pediatr Hematol Oncol 2018 Aug - Sep;35(5-6):316-321. Epub 2019 Jan 25.

a Division of Hematology, Department of Pediatrics, Oncology and Stem Cell Transplant, Ann and Robert H. Lurie Children's Hospital of Chicago, Feinberg School of Medicine , Northwestern University , Chicago , Illinois , USA.

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http://dx.doi.org/10.1080/08880018.2018.1532478DOI Listing
March 2019

SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery.

Blood 2018 Oct 28;132(17):1737-1749. Epub 2018 Aug 28.

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1182/blood-2018-03-840702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202916PMC
October 2018

Fecal calprotectin and serum albumin as markers of gastrointestinal graft versus host disease.

Hematol Oncol Stem Cell Ther 2018 Sep 1;11(3):169-174. Epub 2018 Feb 1.

Department of Pediatrics, Division of Hematology, Oncology and Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S16583876183000
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http://dx.doi.org/10.1016/j.hemonc.2017.12.003DOI Listing
September 2018

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia.

N Engl J Med 2018 04;378(16):1479-1493

From the Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago (A.A.T., M.K.); University of California, San Francisco, Benioff Children's Hospital, Oakland (M.C.W., E.V.), Lucile Salter Packard Children's Hospital at Stanford, Palo Alto (S.S.), and David Geffen School of Medicine, University of California, Los Angeles, Los Angeles (G.J.S.) - all in California; Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia (J.K., D.T.T.); Centenary Institute (J.E.J.R.), University of Sydney, Sydney Medical School (J.E.J.R., P.J.H.), and Royal Prince Alfred Hospital (J.E.J.R., P.J.H.), Camperdown, NSW, Australia; Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris (J.-A.R., E.M., D.M., F.L., P.B., A.M., L.C., J.-S.D., F.S., F.M., V.B., C.B., O.H., M.D.M., S.B., M.C.), Groupe Hospitalier Universitaire Ouest (J.-A.R., A.M., L.C., M.C.), IMAGINE Institute (E.M., M.S., D.M., M.C.), Université Paris Descartes (M.S., C. Poirot, S.H.-B.-A.), Université Paris Diderot (H.P., T.L.), Pierre et Marie Curie University (C. Poirot), and Hôpital Cochin (J.-F.M.), Paris, CEA University Paris-Sud, Institute of Emerging Diseases and Innovative Therapies, Fontenay-aux-Roses (E.P., Y.B., S.C., P.L.), Hôpital Louis-Mourier, Colombes (H.P., T.L.), Centre Hospitalier Intercommunal de Créteil, Créteil (C. Pondarré), and Hôpital Bicêtre, Le Kremlin-Bicêtre (S.H.-B.-A.) - all in France; Bluebird Bio, Cambridge (J.-A.R., S.S., G.V., O.N., R.W.R., D.D., A.P., L.S., M.A.), and Harvard Medical School, Brigham and Women's Hospital, Boston (P.L.) - both in Massachusetts; Ramathibodi Hospital, Mahidol University, Bangkok, Thailand (S.H., U.A., P.L.); and the National Center for Tumor Diseases-German Cancer Research Center, Heidelberg, Germany (C.K.).

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http://dx.doi.org/10.1056/NEJMoa1705342DOI Listing
April 2018

Early mixed T-cell chimerism is predictive of pediatric AML or MDS relapse after hematopoietic stem cell transplant.

Pediatr Blood Cancer 2017 Sep 7;64(9). Epub 2017 Mar 7.

Division of Hematology, Oncology and Stem Cell Transplant, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1002/pbc.26493DOI Listing
September 2017

The Impact of High-resolution HLA-A, HLA-B, HLA-C, and HLA-DRB1 on Transplant-related Outcomes in Single-unit Umbilical Cord Blood Transplantation in Pediatric Patients.

J Pediatr Hematol Oncol 2017 01;39(1):26-32

*Division of Hematology/Oncology/Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago †Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago §Department of Pediatrics, Northwestern University Feinberg School of Medicine ‡Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MPH.0000000000000690DOI Listing
January 2017

Long-term follow-up of children with chronic myeloid leukemia after hematopoietic stem cell transplantation and tyrosine kinase inhibitor therapy.

Leuk Lymphoma 2016 23;57(4):949-52. Epub 2015 Dec 23.

a Department of Pediatrics, Division of Hematology , Oncology and Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine , Chicago , IL , USA ;

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http://dx.doi.org/10.3109/10428194.2015.1065981DOI Listing
December 2016

A Phase I Study of Reduced-Intensity Conditioning and Allogeneic Stem Cell Transplantation Followed by Dose Escalation of Targeted Consolidation Immunotherapy with Gemtuzumab Ozogamicin in Children and Adolescents with CD33+ Acute Myeloid Leukemia.

Biol Blood Marrow Transplant 2016 Apr 16;22(4):698-704. Epub 2016 Jan 16.

Department of Pediatrics, New York Medical College, Valhalla, New York; Departments of Medicine, Pathology, Microbiology and Immunology, and Cell Biology and Anatomy, New York Medical College, Valhalla, New York. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10838791160005
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http://dx.doi.org/10.1016/j.bbmt.2016.01.019DOI Listing
April 2016

Single Daily Busulfan Dosing for Infants with Nonmalignant Diseases Undergoing Reduced-Intensity Conditioning for Allogeneic Hematopoietic Progenitor Cell Transplantation.

Biol Blood Marrow Transplant 2015 Sep 27;21(9):1612-21. Epub 2015 May 27.

Stem Cell Transplant Program, Division of Hematology-Oncology-Transplant, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1016/j.bbmt.2015.05.017DOI Listing
September 2015

Expression of Wilms tumor gene in high risk neuroblastoma: complementary marker to tyrosine hydroxylase for detection of minimal residual disease.

Transl Pediatr 2015 Jul;4(3):219-25

1 Northwestern University Feinberg School of Medicine, Chicago Il, USA ; 2 Lurie Children's Hospital of Chicago Department of Hematology, Oncology and Transplant, Chicago Il, USA ; 3 Stem Cell Transplant Research Laboratory, Chicago Il, USA ; 4 Lurie Children's Hospital of Chicago Department of Pathology, Chicago Il, USA.

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http://dx.doi.org/10.3978/j.issn.2224-4336.2015.07.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729048PMC
July 2015

Secondary malignant neoplasms after high-dose chemotherapy and autologous stem cell rescue for high-risk neuroblastoma.

Pediatr Blood Cancer 2014 Aug 14;61(8):1350-6. Epub 2014 Mar 14.

Division of Hematology/Oncology/Stem Cell Transplant, Ann and Robert H. Lurie Children's Hospital of Chicago, Illinois.

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http://dx.doi.org/10.1002/pbc.25033DOI Listing
August 2014

Scurvy: a new problem for patients with chronic GVHD involving mucous membranes; an easy problem to resolve.

Pediatr Transplant 2014 Aug 12;18(5):524-6. Epub 2014 May 12.

Northwestern University Feinberg School of Medicine, Chicago, IL, USA; Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1111/petr.12285DOI Listing
August 2014

Validation of chimerism in pediatric recipients of allogeneic hematopoietic stem cell transplantation (HSCT) a comparison between two methods: real-time PCR (qPCR) vs. variable number tandem repeats PCR (VNTR PCR).

Chimerism 2013 Jan-Mar;4(1):1-8. Epub 2012 Dec 13.

Stem Cell Transplant Chimerism Laboratory, Department of Hematology-Oncology Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.4161/chim.23158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654730PMC
December 2013

Exostoses as a long-term sequela after pediatric hematopoietic progenitor cell transplantation: potential causes and increase risk of secondary malignancies from Ann & Robert H. Lurie Children's Hospital of Chicago.

Biol Blood Marrow Transplant 2013 Aug 28;19(8):1267-70. Epub 2013 May 28.

Division of Hematology-Oncology-Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.bbmt.2013.05.015DOI Listing
August 2013

Busulfan dosing in children with BMIs ≥ 85% undergoing HSCT: a new optimal strategy.

Biol Blood Marrow Transplant 2011 Sep 1;17(9):1383-8. Epub 2011 Feb 1.

University of Utah, School of Medicine, Department of Pediatrics, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1016/j.bbmt.2011.01.013DOI Listing
September 2011

The use of fluid boluses to safely perform extracorporeal photopheresis (ECP) in low-weight children: a novel procedure.

J Clin Apher 2010 ;25(2):63-9

Division of Hematology/Oncology/Stem Cell Transplantation, The Children's Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60614, USA.

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http://dx.doi.org/10.1002/jca.20231DOI Listing
July 2010

Early elevation of C-reactive protein correlates with severe infection and nonrelapse mortality in children undergoing allogeneic stem cell transplantation.

Biol Blood Marrow Transplant 2010 Mar;16(3):350-7

Department of Pediatrics, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1016/j.bbmt.2009.10.036DOI Listing
March 2010

High WT1 gene expression before haematopoietic stem cell transplant in children with acute myeloid leukaemia predicts poor event-free survival.

Br J Haematol 2009 Sep 23;146(6):669-74. Epub 2009 Jul 23.

Children's Memorial Hospital, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60614, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2009.07770.xDOI Listing
September 2009

A prospective longitudinal multicenter study of coagulation in pediatric patients undergoing allogeneic stem cell transplantation.

Pediatr Blood Cancer 2008 Jun;50(6):1240-6

Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1002/pbc.21473DOI Listing
June 2008

High-risk adenovirus-infected pediatric allogeneic hematopoietic progenitor cell transplant recipients and preemptive cidofovir therapy.

Pediatr Transplant 2008 Mar;12(2):219-27

Division of Pediatric Infectious Diseases, Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Children's Memorial Hospital, Chicago, IL 60614, USA.

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http://dx.doi.org/10.1111/j.1399-3046.2007.00851.xDOI Listing
March 2008

Identification of adenoviruses in specimens from high-risk pediatric stem cell transplant recipients and controls.

J Clin Microbiol 2008 Jan 7;46(1):317-20. Epub 2007 Nov 7.

Children's Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

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http://jcm.asm.org/cgi/doi/10.1128/JCM.01585-07
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http://dx.doi.org/10.1128/JCM.01585-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224268PMC
January 2008

Correction of enzyme levels with allogeneic hematopoeitic progenitor cell transplantation in Niemann-Pick type B.

Pediatr Blood Cancer 2007 Dec;49(7):987-9

Children's Memorial Hospital, Hematology/Oncology/Transplant, Chicago, Illinois, USA.

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http://dx.doi.org/10.1002/pbc.21300DOI Listing
December 2007

Hepatitic pattern of graft versus host disease in children.

Pediatr Blood Cancer 2007 Oct;49(5):727-30

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1002/pbc.21069DOI Listing
October 2007

Tandem high-dose chemotherapy with autologous peripheral hematopoietic progenitor cell rescue as consolidation therapy for patients with high-risk Ewing family tumors.

Pediatr Blood Cancer 2007 Aug;49(2):196-8

Division of Hematology, Children's Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60614-3394, USA.

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http://dx.doi.org/10.1002/pbc.21182DOI Listing
August 2007

Correlation of minimal residual disease by assessing Wilms tumor gene expression and engraftment by variable number of tandem repeats in children with leukemia posthematopoietic stem cell transplantation.

Pediatr Dev Pathol 2006 May-Jun;9(3):203-9

Stem Cell Transplant Laboratory, Department of Hematology, Children's Memorial Hospital, Northwestern Feinberg School of Medicine, Chicago, IL, USA.

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http://dx.doi.org/10.2350/05-12-0004.1DOI Listing
October 2006

Pharmacokinetics of a test dose of intravenous busulfan guide dose modifications to achieve an optimal area under the curve of a single daily dose of intravenous busulfan in children undergoing a reduced-intensity conditioning regimen with hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2006 Apr;12(4):472-9

Stem Cell Transplant Program, Children's Memorial Hospital, Feinberg School of Medicine, Department of Pediatrics, Northwestern University, Chicago, IL 60614, USA.

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http://dx.doi.org/10.1016/j.bbmt.2005.12.028DOI Listing
April 2006

Excellent local tumor control regardless of extent of surgical resection after treatment on the Chicago Pilot II protocol for neuroblastoma.

J Pediatr Surg 2006 Jan;41(1):271-6

Department of Surgery, Children's Memorial Hospital, Chicago, IL 60614, USA.

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http://dx.doi.org/10.1016/j.jpedsurg.2005.10.050DOI Listing
January 2006

Reduced intensity transplants (RIT) in pediatrics: a review.

Pediatr Transplant 2005 Dec;9 Suppl 7:63-70

Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

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http://dx.doi.org/10.1111/j.1399-3046.2005.00446.xDOI Listing
December 2005

Favorable outcome for infant acute lymphoblastic leukemia after hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2005 Dec;11(12):999-1005

Northwestern University, The Feinberg School of Medicine, Children's Memorial Hospital, Chicago, Illinois 60614, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S108387910500536
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http://dx.doi.org/10.1016/j.bbmt.2005.08.031DOI Listing
December 2005

Pediatric transplantation: results in solid tumors.

Curr Hematol Rep 2005 Jul;4(4):260-9

Division of Hematology/Oncology and Stem Cell Transplantation, Department of Pediatrics, Northwestern University Feinberg School of Medicine, 2300 Children's Plaza, Box #30, Chicago, IL, USA.

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July 2005

Autologous hematopoietic stem cell transplantation in patients with refractory Crohn's disease.

Gastroenterology 2005 Mar;128(3):552-63

Division of Immunotherapy, Department of Medicine, Northwestern University Medical Center, Chicago, Illinois 60611, USA.

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March 2005

Neural cell differentiation in vitro from adult human bone marrow mesenchymal stem cells.

Stem Cells Dev 2005 Feb;14(1):65-9

Children's Memorial Research Center, Children's Memorial Hospital, Chicago, IL 60614, USA.

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http://dx.doi.org/10.1089/scd.2005.14.65DOI Listing
February 2005

A new complication of stem cell transplantation: measles inclusion body encephalitis.

Pediatrics 2004 Nov;114(5):e657-60

Division of Infectious Disease, Department of Pediatrics, Northwestern University Feinberg School of Medicine and Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614, USA.

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http://dx.doi.org/10.1542/peds.2004-0949DOI Listing
November 2004

Scintigraphic response by 123I-metaiodobenzylguanidine scan correlates with event-free survival in high-risk neuroblastoma.

J Clin Oncol 2004 Oct;22(19):3909-15

Division of Hematology/Oncology, Department of Pediatrics, Northwestern University, Children's Memorial Hospital, 2300 Children's Plaza, Box #30, Chicago, IL 60614, USA.

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http://dx.doi.org/10.1200/JCO.2004.07.144DOI Listing
October 2004

Reduced intensity haemopoietic stem-cell transplantation for treatment of non-malignant diseases in children.

Lancet 2004 Jul 10-16;364(9429):156-62

Division of Hematology/Oncology/Transplant, Department of Pediatrics, Children's Memorial Hospital, Northwestern University, Feinberg School of Medicine, Chicago, IL 60614, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S014067360416628
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http://dx.doi.org/10.1016/S0140-6736(04)16628-2DOI Listing
July 2004

Eosinophilia correlates with the presence or development of chronic graft-versus-host disease in children.

Transplantation 2004 Apr;77(7):1096-100

Department of Pediatrics, Children's Memorial Hospital, Chicago, IL 60614, USA.

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April 2004

Nonmyeloablative hematopoietic stem cell transplant for X-linked hyper-immunoglobulin m syndrome with cholangiopathy.

Pediatrics 2004 Feb;113(2):e122-7

Department of Pediatrics, Division of Hematology/Oncology/Transplant, Northwestern University, The Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1542/peds.113.2.e122DOI Listing
February 2004

Results of little or no treatment for lymphocyte-predominant Hodgkin disease in children and adolescents.

J Pediatr Hematol Oncol 2003 Sep;25(9):684-7

Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio 78229, USA.

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September 2003

Novel therapeutic approaches in the treatment of children with hepatoblastoma.

J Pediatr Hematol Oncol 2002 Dec;24(9):751-5

Division of Hematology/Oncology, Department of Pediatrics, Northwestern University and Children's Memorial Hospital, Chicago, IL, USA.

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December 2002

Utility of WT1 as a reliable tool for the detection of minimal residual disease in children with leukemia.

Pediatr Dev Pathol 2002 May-Jun;5(3):269-75

Department of Pediatrics, The Stem Cell Transplant Program, Children's Memorial Hospital, Northwestern University Medical School, Box 30, 2300 Children's Plaza, Chicago, IL 60614, USA.

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http://link.springer.de/link/service/journals/10024/bibs/200
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http://dx.doi.org/10.1007/s10024001-0208-xDOI Listing
August 2002

Induction of a transient graft vs. leukemia effect following unrelated cord blood transplantation.

Pediatr Transplant 2002 Aug;6(4):348-51

Division of Hematology/Oncology, Department of Pediatrics, North-western University Medical School, Children's Memorial Hospital, Chicago, Illinois, USA.

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August 2002