Moritz Gartlgruber

Moritz Gartlgruber

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Moritz Gartlgruber

Moritz Gartlgruber

Publications by authors named "Moritz Gartlgruber"

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8Publications

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Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes.

Authors:
Julian Musa Florencia Cidre-Aranaz Marie-Ming Aynaud Martin F Orth Maximilian M L Knott Olivier Mirabeau Gal Mazor Mor Varon Tilman L B Hölting Sandrine Grossetête Moritz Gartlgruber Didier Surdez Julia S Gerke Shunya Ohmura Aruna Marchetto Marlene Dallmayer Michaela C Baldauf Stefanie Stein Giuseppina Sannino Jing Li Laura Romero-Pérez Frank Westermann Wolfgang Hartmann Uta Dirksen Melissa Gymrek Nathaniel D Anderson Adam Shlien Barak Rotblat Thomas Kirchner Olivier Delattre Thomas G P Grünewald

Nat Commun 2019 Sep 11;10(1):4128. Epub 2019 Sep 11.

Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41467-019-12071-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739408PMC
September 2019

A mechanistic classification of clinical phenotypes in neuroblastoma.

Authors:
Sandra Ackermann Maria Cartolano Barbara Hero Anne Welte Yvonne Kahlert Andrea Roderwieser Christoph Bartenhagen Esther Walter Judith Gecht Laura Kerschke Ruth Volland Roopika Menon Johannes M Heuckmann Moritz Gartlgruber Sabine Hartlieb Kai-Oliver Henrich Konstantin Okonechnikov Janine Altmüller Peter Nürnberg Steve Lefever Bram de Wilde Frederik Sand Fakhera Ikram Carolina Rosswog Janina Fischer Jessica Theissen Falk Hertwig Aatur D Singhi Thorsten Simon Wenzel Vogel Sven Perner Barbara Krug Matthias Schmidt Sven Rahmann Viktor Achter Ulrich Lang Christian Vokuhl Monika Ortmann Reinhard Büttner Angelika Eggert Frank Speleman Roderick J O'Sullivan Roman K Thomas Frank Berthold Jo Vandesompele Alexander Schramm Frank Westermann Johannes H Schulte Martin Peifer Matthias Fischer

Science 2018 12;362(6419):1165-1170

Department of Experimental Pediatric Oncology, University Children's Hospital of Cologne, Medical Faculty, Cologne, Germany.

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http://www.sciencemag.org/lookup/doi/10.1126/science.aat6768
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http://dx.doi.org/10.1126/science.aat6768DOI Listing
December 2018

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.

Authors:
Bieke Decaesteker Geertrui Denecker Christophe Van Neste Emmy M Dolman Wouter Van Loocke Moritz Gartlgruber Carolina Nunes Fanny De Vloed Pauline Depuydt Karen Verboom Dries Rombaut Siebe Loontiens Jolien De Wyn Waleed M Kholosy Bianca Koopmans Anke H W Essing Carl Herrmann Daniel Dreidax Kaat Durinck Dieter Deforce Filip Van Nieuwerburgh Anton Henssen Rogier Versteeg Valentina Boeva Gudrun Schleiermacher Johan van Nes Pieter Mestdagh Suzanne Vanhauwaert Johannes H Schulte Frank Westermann Jan J Molenaar Katleen De Preter Frank Speleman

Nat Commun 2018 11 19;9(1):4866. Epub 2018 Nov 19.

Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.

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http://www.nature.com/articles/s41467-018-06699-9
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http://dx.doi.org/10.1038/s41467-018-06699-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242972PMC
November 2018

Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas.

Authors:
Kai-Oliver Henrich Sebastian Bender Maral Saadati Daniel Dreidax Moritz Gartlgruber Chunxuan Shao Carl Herrmann Manuel Wiesenfarth Martha Parzonka Lea Wehrmann Matthias Fischer David J Duffy Emma Bell Alica Torkov Peter Schmezer Christoph Plass Thomas Höfer Axel Benner Stefan M Pfister Frank Westermann

Cancer Res 2016 09 7;76(18):5523-37. Epub 2016 Sep 7.

Neuroblastoma Genomics B087, German Cancer Research Center, Heidelberg, Germany. k.henrich@dkfz

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2507DOI Listing
September 2016

The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells.

Authors:
Sonja Textor Felicitas Bossler Kai-Oliver Henrich Moritz Gartlgruber Julia Pollmann Nathalie Fiegler Annette Arnold Frank Westermann Nina Waldburger Kai Breuhahn Sven Golfier Mathias Witzens-Harig Adelheid Cerwenka

Oncoimmunology 2016 Jul 28;5(7):e1116674. Epub 2016 Jul 28.

Innate Immunity Group, German Cancer Research Center (DKFZ) , Heidelberg, Germany.

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http://dx.doi.org/10.1080/2162402X.2015.1116674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007025PMC
July 2016

Telomerase activation by genomic rearrangements in high-risk neuroblastoma.

Authors:
Martin Peifer Falk Hertwig Frederik Roels Daniel Dreidax Moritz Gartlgruber Roopika Menon Andrea Krämer Justin L Roncaioli Frederik Sand Johannes M Heuckmann Fakhera Ikram Rene Schmidt Sandra Ackermann Anne Engesser Yvonne Kahlert Wenzel Vogel Janine Altmüller Peter Nürnberg Jean Thierry-Mieg Danielle Thierry-Mieg Aruljothi Mariappan Stefanie Heynck Erika Mariotti Kai-Oliver Henrich Christian Gloeckner Graziella Bosco Ivo Leuschner Michal R Schweiger Larissa Savelyeva Simon C Watkins Chunxuan Shao Emma Bell Thomas Höfer Viktor Achter Ulrich Lang Jessica Theissen Ruth Volland Maral Saadati Angelika Eggert Bram de Wilde Frank Berthold Zhiyu Peng Chen Zhao Leming Shi Monika Ortmann Reinhard Büttner Sven Perner Barbara Hero Alexander Schramm Johannes H Schulte Carl Herrmann Roderick J O'Sullivan Frank Westermann Roman K Thomas Matthias Fischer

Nature 2015 Oct 14;526(7575):700-4. Epub 2015 Oct 14.

Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931 Cologne, Germany.

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http://dx.doi.org/10.1038/nature14980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881306PMC
October 2015

MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma.

Authors:
Anneleen Beckers Gert Van Peer Daniel R Carter Moritz Gartlgruber Carl Herrmann Saurabh Agarwal Hetty H Helsmoortel Kristina Althoff Jan J Molenaar Belamy B Cheung Johannes H Schulte Yves Benoit Jason M Shohet Frank Westermann Glenn M Marshall Jo Vandesompele Katleen De Preter Frank Speleman

Cancer Lett 2015 Sep 26;366(1):123-32. Epub 2015 Jun 26.

Center for Medical Genetics (CMGG), Ghent University, Medical Research Building (MRB1), De Pintelaan 185, 9000 Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2015.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837470PMC
September 2015

Mutational dynamics between primary and relapse neuroblastomas.

Authors:
Alexander Schramm Johannes Köster Yassen Assenov Kristina Althoff Martin Peifer Ellen Mahlow Andrea Odersky Daniela Beisser Corinna Ernst Anton G Henssen Harald Stephan Christopher Schröder Lukas Heukamp Anne Engesser Yvonne Kahlert Jessica Theissen Barbara Hero Frederik Roels Janine Altmüller Peter Nürnberg Kathy Astrahantseff Christian Gloeckner Katleen De Preter Christoph Plass Sangkyun Lee Holger N Lode Kai-Oliver Henrich Moritz Gartlgruber Frank Speleman Peter Schmezer Frank Westermann Sven Rahmann Matthias Fischer Angelika Eggert Johannes H Schulte

Nat Genet 2015 Aug 29;47(8):872-7. Epub 2015 Jun 29.

1] Pediatric Oncology and Hematology, University Children's Hospital Essen, University of Duisburg-Essen, Essen, Germany. [2] Pediatric Oncology and Hematology, Charité University Medicine, Berlin, Germany. [3] German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.

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http://search.proquest.com/openview/bef3fe020af3cd6708016aba
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http://dx.doi.org/10.1038/ng.3349DOI Listing
August 2015