Publications by authors named "Morio Ueno"

74Publications

Pluripotent epigenetic regulator OBP-801 maintains filtering blebs in glaucoma filtration surgery model.

Sci Rep 2020 Dec 1;10(1):20936. Epub 2020 Dec 1.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Hirokoji-agaru, Kawaramachi-dori, Kamigyo-ku, Kyoto, 602-8566, Japan.

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http://dx.doi.org/10.1038/s41598-020-77811-7DOI Listing
December 2020

Five-Year Follow-up of First Eleven Cases Undergoing Injection of Cultured Corneal Endothelial Cells for Corneal Endothelial Failure.

Ophthalmology 2020 Sep 5. Epub 2020 Sep 5.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2020.09.002DOI Listing
September 2020

Choroidal detachment-induced secondary angle-closure after trabeculectomy in patient with ocular venous congestion: A case report.

Am J Ophthalmol Case Rep 2020 Sep 15;19:100782. Epub 2020 Jun 15.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of 
Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.ajoc.2020.100782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306613PMC
September 2020

Morphological change and recovery of corneal endothelial cells after rho-associated protein kinase inhibitor eye-drop (ripasudil 0.4%) instillation.

Br J Ophthalmol 2020 Apr 8. Epub 2020 Apr 8.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1136/bjophthalmol-2019-315776DOI Listing
April 2020

Safety and Efficacy of Long-Term Ripasudil 0.4% Instillation for the Reduction of Intraocular Pressure in Japanese Open-Angle Glaucoma Patients.

J Ocul Pharmacol Ther 2020 05 12;36(4):229-233. Epub 2020 Mar 12.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1089/jop.2019.0125DOI Listing
May 2020

Longitudinal seasonal variations of intraocular pressure in primary open-angle glaucoma patients as revealed by real-world data.

Acta Ophthalmol 2020 Feb 3. Epub 2020 Feb 3.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1111/aos.14365DOI Listing
February 2020

Ultrastructural variability of the juxtacanalicular tissue along the inner wall of Schlemm's canal.

Mol Vis 2019 21;25:517-526. Epub 2019 Sep 21.

Structural Biophysics Research Group, School of Optometry and Vision Sciences, Cardiff University, Wales, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776461PMC
April 2020

In Vivo Fluorescence Visualization of Anterior Chamber Injected Human Corneal Endothelial Cells Labeled With Quantum Dots.

Invest Ophthalmol Vis Sci 2019 09;60(12):4008-4020

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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https://iovs.arvojournals.org/article.aspx?articleid=2752220
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http://dx.doi.org/10.1167/iovs.19-27788DOI Listing
September 2019

Core Transcription Factors Promote Induction of PAX3-Positive Skeletal Muscle Stem Cells.

Stem Cell Reports 2019 08 25;13(2):352-365. Epub 2019 Jul 25.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.stemcr.2019.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700474PMC
August 2019

Human Skeletal Muscle Cells Derived from the Orbicularis Oculi Have Regenerative Capacity for Duchenne Muscular Dystrophy.

Int J Mol Sci 2019 Jul 14;20(14). Epub 2019 Jul 14.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.

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http://dx.doi.org/10.3390/ijms20143456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679213PMC
July 2019

A physical biomarker of the quality of cultured corneal endothelial cells and of the long-term prognosis of corneal restoration in patients.

Nat Biomed Eng 2019 12 22;3(12):953-960. Epub 2019 Jul 22.

Center for Integrative Medicine and Physics, Institute for Advanced Study, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1038/s41551-019-0429-9DOI Listing
December 2019

Cultured Cells and ROCK Inhibitor for Bullous Keratopathy.

N Engl J Med 2018 09;379(12):1185

Kyoto Prefectural University of Medicine, Kyoto, Japan

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http://www.nejm.org/doi/10.1056/NEJMc1805808
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http://dx.doi.org/10.1056/NEJMc1805808DOI Listing
September 2018

Curcumin and its demethoxy derivatives possess p300 HAT inhibitory activity and suppress hypertrophic responses in cardiomyocytes.

J Pharmacol Sci 2018 Apr 13;136(4):212-217. Epub 2018 Mar 13.

Division of Molecular Medicine, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka 422-8526, Japan; Shizuoka General Hospital, Shizuoka 420-8527, Japan; Clinical Research Institute, Kyoto Medical Center, National Hospital Organization, Kyoto 612-8555, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jphs.2017.12.013DOI Listing
April 2018

Injection of Cultured Cells with a ROCK Inhibitor for Bullous Keratopathy.

N Engl J Med 2018 Mar;378(11):995-1003

From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) - both in Kyoto, Japan.

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http://dx.doi.org/10.1056/NEJMoa1712770DOI Listing
March 2018

Severe Corneal Disorders Developed After Brimonidine Tartrate Ophthalmic Solution Use.

Cornea 2017 Dec;36(12):1567-1569

*Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan; †Department of Ophthalmology, Fukuchiyama City Hospital, Kyoto, Japan; ‡Oike-Ganka Ikeda Clinic, Kyoto, Japan; §Department of Ophthalmology, National Center for Geriatrics and Gerontology, Obu, Japan; and ¶Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1097/ICO.0000000000001370DOI Listing
December 2017

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.

Authors:
Tin Aung Mineo Ozaki Mei Chin Lee Ursula Schlötzer-Schrehardt Gudmar Thorleifsson Takanori Mizoguchi Robert P Igo Aravind Haripriya Susan E Williams Yury S Astakhov Andrew C Orr Kathryn P Burdon Satoko Nakano Kazuhiko Mori Khaled Abu-Amero Michael Hauser Zheng Li Gopalakrishnan Prakadeeswari Jessica N Cooke Bailey Alina Popa Cherecheanu Jae H Kang Sarah Nelson Ken Hayashi Shin-Ichi Manabe Shigeyasu Kazama Tomasz Zarnowski Kenji Inoue Murat Irkec Miguel Coca-Prados Kazuhisa Sugiyama Irma Järvelä Patricio Schlottmann S Fabian Lerner Hasnaa Lamari Yildirim Nilgün Mukharram Bikbov Ki Ho Park Soon Cheol Cha Kenji Yamashiro Juan C Zenteno Jost B Jonas Rajesh S Kumar Shamira A Perera Anita S Y Chan Nino Kobakhidze Ronnie George Lingam Vijaya Tan Do Deepak P Edward Lourdes de Juan Marcos Mohammad Pakravan Sasan Moghimi Ryuichi Ideta Daniella Bach-Holm Per Kappelgaard Barbara Wirostko Samuel Thomas Daniel Gaston Karen Bedard Wenda L Greer Zhenglin Yang Xueyi Chen Lulin Huang Jinghong Sang Hongyan Jia Liyun Jia Chunyan Qiao Hui Zhang Xuyang Liu Bowen Zhao Ya-Xing Wang Liang Xu Stéphanie Leruez Pascal Reynier George Chichua Sergo Tabagari Steffen Uebe Matthias Zenkel Daniel Berner Georg Mossböck Nicole Weisschuh Ursula Hoja Ulrich-Christoph Welge-Luessen Christian Mardin Panayiota Founti Anthi Chatzikyriakidou Theofanis Pappas Eleftherios Anastasopoulos Alexandros Lambropoulos Arkasubhra Ghosh Rohit Shetty Natalia Porporato Vijayan Saravanan Rengaraj Venkatesh Chandrashekaran Shivkumar Narendran Kalpana Sripriya Sarangapani Mozhgan R Kanavi Afsaneh Naderi Beni Shahin Yazdani Alireza Lashay Homa Naderifar Nassim Khatibi Antonio Fea Carlo Lavia Laura Dallorto Teresa Rolle Paolo Frezzotti Daniela Paoli Erika Salvi Paolo Manunta Yosai Mori Kazunori Miyata Tomomi Higashide Etsuo Chihara Satoshi Ishiko Akitoshi Yoshida Masahide Yanagi Yoshiaki Kiuchi Tsutomu Ohashi Toshiya Sakurai Takako Sugimoto Hideki Chuman Makoto Aihara Masaru Inatani Masahiro Miyake Norimoto Gotoh Fumihiko Matsuda Nagahisa Yoshimura Yoko Ikeda Morio Ueno Chie Sotozono Jin Wook Jeoung Min Sagong Kyu Hyung Park Jeeyun Ahn Marisa Cruz-Aguilar Sidi M Ezzouhairi Abderrahman Rafei Yaan Fun Chong Xiao Yu Ng Shuang Ru Goh Yueming Chen Victor H K Yong Muhammad Imran Khan Olusola O Olawoye Adeyinka O Ashaye Idakwo Ugbede Adeola Onakoya Nkiru Kizor-Akaraiwe Chaiwat Teekhasaenee Yanin Suwan Wasu Supakontanasan Suhanya Okeke Nkechi J Uche Ifeoma Asimadu Humaira Ayub Farah Akhtar Ewa Kosior-Jarecka Urszula Lukasik Ignacio Lischinsky Vania Castro Rodolfo Perez Grossmann Gordana Sunaric Megevand Sylvain Roy Edward Dervan Eoin Silke Aparna Rao Priti Sahay Pablo Fornero Osvaldo Cuello Delia Sivori Tamara Zompa Richard A Mills Emmanuelle Souzeau Paul Mitchell Jie Jin Wang Alex W Hewitt Michael Coote Jonathan G Crowston Sergei Y Astakhov Eugeny L Akopov Anton Emelyanov Vera Vysochinskaya Gyulli Kazakbaeva Rinat Fayzrakhmanov Saleh A Al-Obeidan Ohoud Owaidhah Leyla Ali Aljasim Balram Chowbay Jia Nee Foo Raphael Q Soh Kar Seng Sim Zhicheng Xie Augustine W O Cheong Shi Qi Mok Hui Meng Soo Xiao Yin Chen Su Qin Peh Khai Koon Heng Rahat Husain Su-Ling Ho Axel M Hillmer Ching-Yu Cheng Francisco A Escudero-Domínguez Rogelio González-Sarmiento Frederico Martinon-Torres Antonio Salas Kessara Pathanapitoon Linda Hansapinyo Boonsong Wanichwecharugruang Naris Kitnarong Anavaj Sakuntabhai Hip X Nguyn Giang T T Nguyn Trình V Nguyn Werner Zenz Alexander Binder Daniela S Klobassa Martin L Hibberd Sonia Davila Stefan Herms Markus M Nöthen Susanne Moebus Robyn M Rautenbach Ari Ziskind Trevor R Carmichael Michele Ramsay Lydia Álvarez Montserrat García Héctor González-Iglesias Pedro P Rodríguez-Calvo Luis Fernández-Vega Cueto Çilingir Oguz Nevbahar Tamcelik Eray Atalay Bilge Batu Dilek Aktas Burcu Kasım M Roy Wilson Anne L Coleman Yutao Liu Pratap Challa Leon Herndon Rachel W Kuchtey John Kuchtey Karen Curtin Craig J Chaya Alan Crandall Linda M Zangwill Tien Yin Wong Masakazu Nakano Shigeru Kinoshita Anneke I den Hollander Eija Vesti John H Fingert Richard K Lee Arthur J Sit Bradford J Shingleton Ningli Wang Daniele Cusi Raheel Qamar Peter Kraft Margaret A Pericak-Vance Soumya Raychaudhuri Steffen Heegaard Tero Kivelä André Reis Friedrich E Kruse Robert N Weinreb Louis R Pasquale Jonathan L Haines Unnur Thorsteinsdottir Fridbert Jonasson R Rand Allingham Dan Milea Robert Ritch Toshiaki Kubota Kei Tashiro Eranga N Vithana Shazia Micheal Fotis Topouzis Jamie E Craig Michael Dubina Periasamy Sundaresan Kari Stefansson Janey L Wiggs Francesca Pasutto Chiea Chuen Khor

Nat Genet 2017 07 29;49(7):993-1004. Epub 2017 May 29.

Singapore Eye Research Institute, Singapore.

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http://dx.doi.org/10.1038/ng.3875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685441PMC
July 2017

Production of Homogeneous Cultured Human Corneal Endothelial Cells Indispensable for Innovative Cell Therapy.

Invest Ophthalmol Vis Sci 2017 04;58(4):2011-2020

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.16-20703DOI Listing
April 2017

Long-Term Clinical Course in Eyes With Peters Anomaly.

Cornea 2017 Apr;36(4):448-451

Departments of *Ophthalmology; and †Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1097/ICO.0000000000001161DOI Listing
April 2017

The Ingenious Interactions Between Macrophages and Functionally Plastic Retinal Pigment Epithelium Cells.

Invest Ophthalmol Vis Sci 2016 Nov;57(14):5945-5953

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.16-20604DOI Listing
November 2016

MicroRNA Profiles Qualify Phenotypic Features of Cultured Human Corneal Endothelial Cells.

Invest Ophthalmol Vis Sci 2016 Oct;57(13):5509-5517

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.16-19804DOI Listing
October 2016

Metabolic Plasticity in Cell State Homeostasis and Differentiation of Cultured Human Corneal Endothelial Cells.

Invest Ophthalmol Vis Sci 2016 Aug;57(10):4452-4463

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.16-19807DOI Listing
August 2016

Cell Homogeneity Indispensable for Regenerative Medicine by Cultured Human Corneal Endothelial Cells.

Invest Ophthalmol Vis Sci 2016 09;57(11):4749-61

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.16-19770DOI Listing
September 2016

Allogeneic Sensitization and Tolerance Induction After Corneal Endothelial Cell Transplantation in Mice.

Invest Ophthalmol Vis Sci 2016 09;57(11):4572-80

Department of Ophthalmology Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.15-19020DOI Listing
September 2016

The Different Binding Properties of Cultured Human Corneal Endothelial Cell Subpopulations to Descemet's Membrane Components.

Invest Ophthalmol Vis Sci 2016 09;57(11):4599-605

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.16-20087DOI Listing
September 2016

Concomitant Evaluation of a Panel of Exosome Proteins and MiRs for Qualification of Cultured Human Corneal Endothelial Cells.

Invest Ophthalmol Vis Sci 2016 08;57(10):4393-402

Department of Ophthalmology Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.16-19805DOI Listing
August 2016

Cultured Human Corneal Endothelial Cell Aneuploidy Dependence on the Presence of Heterogeneous Subpopulations With Distinct Differentiation Phenotypes.

Invest Ophthalmol Vis Sci 2016 08;57(10):4385-92

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.16-19771DOI Listing
August 2016

Gene Signature-Based Development of ELISA Assays for Reproducible Qualification of Cultured Human Corneal Endothelial Cells.

Invest Ophthalmol Vis Sci 2016 08;57(10):4295-305

Department of Ophthalmology Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.16-19806DOI Listing
August 2016

OVOL2 Maintains the Transcriptional Program of Human Corneal Epithelium by Suppressing Epithelial-to-Mesenchymal Transition.

Cell Rep 2016 05 28;15(6):1359-68. Epub 2016 Apr 28.

Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho Shogoin Sakyo-ku, Kyoto 606-8507, Japan; CREST (Core Research for Evolutional Science and Technology), JST (Japan Science and Technology Agency), Honcho 4-1-8 Kawaguchi, Saitama 332-0012, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.04.020DOI Listing
May 2016

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.

Authors:
Chiea Chuen Khor Tan Do Hongyan Jia Masakazu Nakano Ronnie George Khaled Abu-Amero Roopam Duvesh Li Jia Chen Zheng Li Monisha E Nongpiur Shamira A Perera Chunyan Qiao Hon-Tym Wong Hiroshi Sakai Mônica Barbosa de Melo Mei-Chin Lee Anita S Chan Yaakub Azhany Thi Lam Huong Dao Yoko Ikeda Rodolfo A Perez-Grossmann Tomasz Zarnowski Alexander C Day Jost B Jonas Pancy O S Tam Tuan Anh Tran Humaira Ayub Farah Akhtar Shazia Micheal Paul T K Chew Leyla A Aljasim Tanuj Dada Tam Thi Luu Mona S Awadalla Naris Kitnarong Boonsong Wanichwecharungruang Yee Yee Aung Jelinar Mohamed-Noor Saravanan Vijayan Sripriya Sarangapani Rahat Husain Aliza Jap Mani Baskaran David Goh Daniel H Su Huaizhou Wang Vernon K Yong Leonard W Yip Tuyet Bach Trinh Manchima Makornwattana Thanh Thu Nguyen Edgar U Leuenberger Ki-Ho Park Widya Artini Wiyogo Rajesh S Kumar Celso Tello Yasuo Kurimoto Suman S Thapa Kessara Pathanapitoon John F Salmon Yong Ho Sohn Antonio Fea Mineo Ozaki Jimmy S M Lai Visanee Tantisevi Chaw Chaw Khaing Takanori Mizoguchi Satoko Nakano Chan-Yun Kim Guangxian Tang Sujie Fan Renyi Wu Hailin Meng Thi Thuy Giang Nguyen Tien Dat Tran Morio Ueno Jose Maria Martinez Norlina Ramli Yin Mon Aung Rigo Daniel Reyes Stephen A Vernon Seng Kheong Fang Zhicheng Xie Xiao Yin Chen Jia Nee Foo Kar Seng Sim Tina T Wong Desmond T Quek Rengaraj Venkatesh Srinivasan Kavitha Subbiah R Krishnadas Nagaswamy Soumittra Balekudaru Shantha Boon-Ang Lim Jeanne Ogle José P C de Vasconcellos Vital P Costa Ricardo Y Abe Bruno B de Souza Chelvin C Sng Maria C Aquino Ewa Kosior-Jarecka Guillermo Barreto Fong Vania Castro Tamanaja Ricardo Fujita Yuzhen Jiang Naushin Waseem Sancy Low Huan Nguyen Pham Sami Al-Shahwan E Randy Craven Muhammad Imran Khan Rrima Dada Kuldeep Mohanty Muneeb A Faiq Alex W Hewitt Kathryn P Burdon Eng Hui Gan Anuwat Prutthipongsit Thipnapa Patthanathamrongkasem Mary Ann T Catacutan Irene R Felarca Chona S Liao Emma Rusmayani Vira Wardhana Istiantoro Giulia Consolandi Giulia Pignata Carlo Lavia Prin Rojanapongpun Lerprat Mangkornkanokpong Sunee Chansangpetch Jonathan C H Chan Bonnie N K Choy Jennifer W H Shum Hlaing May Than Khin Thida Oo Aye Thi Han Victor H Yong Xiao-Yu Ng Shuang Ru Goh Yaan Fun Chong Martin L Hibberd Mark Seielstad Eileen Png Sarah J Dunstan Nguyen Van Vinh Chau Jinxin Bei Yi Xin Zeng Abhilasha Karkey Buddha Basnyat Francesca Pasutto Daniela Paoli Paolo Frezzotti Jie Jin Wang Paul Mitchell John H Fingert R Rand Allingham Michael A Hauser Soon Thye Lim Soo Hong Chew Richard P Ebstein Anavaj Sakuntabhai Kyu Hyung Park Jeeyun Ahn Greet Boland Harm Snippe Richard Stead Raquel Quino Su Nyunt Zaw Urszula Lukasik Rohit Shetty Mimiwati Zahari Hyoung Won Bae Nay Lin Oo Toshiaki Kubota Anita Manassakorn Wing Lau Ho Laura Dallorto Young Hoon Hwang Christine A Kiire Masako Kuroda Zeiras Eka Djamal Jovell Ian M Peregrino Arkasubhra Ghosh Jin Wook Jeoung Tung S Hoan Nuttamon Srisamran Thayanithi Sandragasu Saw Htoo Set Vi Huyen Doan Shomi S Bhattacharya Ching-Lin Ho Donald T Tan Ramanjit Sihota Seng-Chee Loon Kazuhiko Mori Shigeru Kinoshita Anneke I den Hollander Raheel Qamar Ya-Xing Wang Yik Y Teo E-Shyong Tai Curt Hartleben-Matkin David Lozano-Giral Seang Mei Saw Ching-Yu Cheng Juan C Zenteno Chi Pui Pang Huong T T Bui Owen Hee Jamie E Craig Deepak P Edward Michiko Yonahara Jamil Miguel Neto Maria L Guevara-Fujita Liang Xu Robert Ritch Ahmad Tajudin Liza-Sharmini Tien Y Wong Saleh Al-Obeidan Nhu Hon Do Periasamy Sundaresan Clement C Tham Paul J Foster Lingam Vijaya Kei Tashiro Eranga N Vithana Ningli Wang Tin Aung

Nat Genet 2016 May 4;48(5):556-62. Epub 2016 Apr 4.

Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.

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http://www.nature.com/articles/ng.3540
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http://dx.doi.org/10.1038/ng.3540DOI Listing
May 2016

Amniotic membrane-assisted trabeculectomy for refractory glaucoma with corneal disorders.

Int Med Case Rep J 2016 25;9:9-14. Epub 2016 Jan 25.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.2147/IMCRJ.S96306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734797PMC
February 2016

Erratum to: Testosterone stimulates glucose uptake and GLUT4 translocation through LKB1/AMPK signaling in 3T3-L1 adipocytes.

Endocrine 2016 May;52(2):402-3

Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.

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http://dx.doi.org/10.1007/s12020-016-0864-2DOI Listing
May 2016

Comparison between bimatoprost and latanoprost-timolol fixed combination for efficacy and safety after switching patients from latanoprost.

Clin Ophthalmol 2015 7;9:1429-36. Epub 2015 Aug 7.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.2147/OPTH.S87613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535543PMC
August 2015

Testosterone stimulates glucose uptake and GLUT4 translocation through LKB1/AMPK signaling in 3T3-L1 adipocytes.

Endocrine 2016 Jan 23;51(1):174-84. Epub 2015 Jun 23.

Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.

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http://link.springer.com/content/pdf/10.1007%2Fs12020-015-06
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http://link.springer.com/10.1007/s12020-015-0666-y
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http://dx.doi.org/10.1007/s12020-015-0666-yDOI Listing
January 2016

Corrigendum: a common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.

Authors:
Tin Aung Mineo Ozaki Takanori Mizoguchi R Rand Allingham Zheng Li Aravind Haripriya Satoko Nakano Steffen Uebe Jeffrey M Harder Anita S Y Chan Mei Chin Lee Kathryn P Burdon Yury S Astakhov Khaled K Abu-Amero Juan C Zenteno Yildirim Nilgün Tomasz Zarnowski Mohammad Pakravan Leen Abu Safieh Liyun Jia Ya Xing Wang Susan Williams Daniela Paoli Patricio G Schlottmann Lulin Huang Kar Seng Sim Jia Nee Foo Masakazu Nakano Yoko Ikeda Rajesh S Kumar Morio Ueno Shin-Ichi Manabe Ken Hayashi Shigeyasu Kazama Ryuichi Ideta Yosai Mori Kazunori Miyata Kazuhisa Sugiyama Tomomi Higashide Etsuo Chihara Kenji Inoue Satoshi Ishiko Akitoshi Yoshida Masahide Yanagi Yoshiaki Kiuchi Makoto Aihara Tsutomu Ohashi Toshiya Sakurai Takako Sugimoto Hideki Chuman Fumihiko Matsuda Kenji Yamashiro Norimoto Gotoh Masahiro Miyake Sergei Y Astakhov Essam A Osman Saleh A Al-Obeidan Ohoud Owaidhah Leyla Al-Jasim Sami Al Shahwan Rhys A Fogarty Paul Leo Yaz Yetkin Çilingir Oğuz Mozhgan Rezaei Kanavi Afsaneh Naderi Beni Shahin Yazdani Evgeny L Akopov Kai-Yee Toh Gareth R Howell Andrew C Orr Yufen Goh Wee Yang Meah Su Qin Peh Ewa Kosior-Jarecka Urszula Lukasik Mandy Krumbiegel Eranga N Vithana Tien Yin Wong Yutao Liu Allison E Ashley Koch Pratap Challa Robyn M Rautenbach David A Mackey Alex W Hewitt Paul Mitchell Jie Jin Wang Ari Ziskind Trevor Carmichael Rangappa Ramakrishnan Kalpana Narendran Rangaraj Venkatesh Saravanan Vijayan Peiquan Zhao Xueyi Chen Dalia Guadarrama-Vallejo Ching Yu Cheng Shamira A Perera Rahat Husain Su-Ling Ho Ulrich-Christoph Welge-Luessen Christian Mardin Ursula Schloetzer-Schrehardt Axel M Hillmer Stefan Herms Susanne Moebus Markus M Nöthen Nicole Weisschuh Rohit Shetty Arkasubhra Ghosh Yik Ying Teo Matthew A Brown Ignacio Lischinsky Jonathan G Crowston Michae Coote Bowen Zhao Jinghong Sang Nihong Zhang Qisheng You Vera Vysochinskaya Panayiota Founti Anthoula Chatzikyriakidou Alexandros Lambropoulos Eleftherios Anastasopoulos Anne L Coleman M Roy Wilson Douglas J Rhee Jae Hee Kang Inna May-Bolchakova Steffen Heegaard Kazuhiko Mori Wallace L M Alward Jost B Jonas Liang Xu Jeffrey M Liebmann Balram Chowbay Elke Schaeffeler Matthias Schwab Fabian Lerner Ningli Wang Zhenglin Yang Paolo Frezzotti Shigeru Kinoshita John H Fingert Masaru Inatani Kei Tashiro André Reis Deepak P Edward Louis R Pasquale Toshiaki Kubota Janey L Wiggs Francesca Pasutto Fotis Topouzis Michael Dubina Jamie E Craig Nagahisa Yoshimura Periasamy Sundaresan Simon W M John Robert Ritch Michael A Hauser Chiea-Chuen Khor

Nat Genet 2015 Jun;47(6):689

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http://dx.doi.org/10.1038/ng0615-689cDOI Listing
June 2015

Colloidal submicron-particle curcumin exhibits high absorption efficiency-a double-blind, 3-way crossover study.

J Nutr Sci Vitaminol (Tokyo) 2015 ;61(1):37-44

Division of Molecular Medicine, School of Pharmaceutical Sciences, University of Shizuoka 2) Shizuoka General Hospital 3) Division of Translational Research, Kyoto Medical Center, National Hospital Organization .

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February 2016

A common variant near TGFBR3 is associated with primary open angle glaucoma.

Authors:
Zheng Li R Rand Allingham Masakazu Nakano Liyun Jia Yuhong Chen Yoko Ikeda Baskaran Mani Li-Jia Chen Changwon Kee David F Garway-Heath Sarangapani Sripriya Nobuo Fuse Khaled K Abu-Amero Chukai Huang Prasanthi Namburi Kathryn Burdon Shamira A Perera Puya Gharahkhani Ying Lin Morio Ueno Mineo Ozaki Takanori Mizoguchi Subbiah Ramasamy Krishnadas Essam A Osman Mei Chin Lee Anita S Y Chan Liza-Sharmini A Tajudin Tan Do Aurelien Goncalves Pascal Reynier Hong Zhang Rupert Bourne David Goh David Broadway Rahat Husain Anil K Negi Daniel H Su Ching-Lin Ho Augusto Azuara Blanco Christopher K S Leung Tina T Wong Azhany Yakub Yutao Liu Monisha E Nongpiur Jong Chul Han Do Nhu Hon Balekudaru Shantha Bowen Zhao Jinghong Sang NiHong Zhang Ryuichi Sato Kengo Yoshii Songhomita Panda-Jonas Allison E Ashley Koch Leon W Herndon Sayoko E Moroi Pratap Challa Jia Nee Foo Jin-Xin Bei Yi-Xin Zeng Cameron P Simmons Tran Nguyen Bich Chau Philomenadin Ferdinamarie Sharmila Merwyn Chew Blanche Lim Pansy O S Tam Elaine Chua Xiao Yu Ng Victor H K Yong Yaan Fun Chong Wee Yang Meah Saravanan Vijayan Sohn Seongsoo Wang Xu Yik Ying Teo Jessica N Cooke Bailey Jae H Kang Jonathan L Haines Ching Yu Cheng Seang-Mei Saw E-Shyong Tai Julia E Richards Robert Ritch Douglas E Gaasterland Louis R Pasquale Jianjun Liu Jost B Jonas Dan Milea Ronnie George Saleh A Al-Obeidan Kazuhiko Mori Stuart Macgregor Alex W Hewitt Christopher A Girkin Mingzhi Zhang Periasamy Sundaresan Lingam Vijaya David A Mackey Tien Yin Wong Jamie E Craig Xinghuai Sun Shigeru Kinoshita Janey L Wiggs Chiea-Chuen Khor Zhenglin Yang Chi Pui Pang Ningli Wang Michael A Hauser Kei Tashiro Tin Aung Eranga N Vithana

Hum Mol Genet 2015 Jul 10;24(13):3880-92. Epub 2015 Apr 10.

Singapore Eye Research Institute, Department of Ophthalmology, Yong Loo Lin School of Medicine, Duke-NUS Graduate Medical School, Singapore, Singapore,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459396PMC
July 2015

A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.

Authors:
Tin Aung Mineo Ozaki Takanori Mizoguchi R Rand Allingham Zheng Li Aravind Haripriya Satoko Nakano Steffen Uebe Jeffrey M Harder Anita S Y Chan Mei Chin Lee Kathryn P Burdon Yury S Astakhov Khaled K Abu-Amero Juan C Zenteno Yildirim Nilgün Tomasz Zarnowski Mohammad Pakravan Leen Abu Safieh Liyun Jia Ya Xing Wang Susan Williams Daniela Paoli Patricio G Schlottmann Lulin Huang Kar Seng Sim Jia Nee Foo Masakazu Nakano Yoko Ikeda Rajesh S Kumar Morio Ueno Shin-ichi Manabe Ken Hayashi Shigeyasu Kazama Ryuichi Ideta Yosai Mori Kazunori Miyata Kazuhisa Sugiyama Tomomi Higashide Etsuo Chihara Kenji Inoue Satoshi Ishiko Akitoshi Yoshida Masahide Yanagi Yoshiaki Kiuchi Makoto Aihara Tsutomu Ohashi Toshiya Sakurai Takako Sugimoto Hideki Chuman Fumihiko Matsuda Kenji Yamashiro Norimoto Gotoh Masahiro Miyake Sergei Y Astakhov Essam A Osman Saleh A Al-Obeidan Ohoud Owaidhah Leyla Al-Jasim Sami Al Shahwan Rhys A Fogarty Paul Leo Yaz Yetkin Çilingir Oğuz Mozhgan Rezaei Kanavi Afsaneh Nederi Beni Shahin Yazdani Evgeny L Akopov Kai-Yee Toh Gareth R Howell Andrew C Orr Yufen Goh Wee Yang Meah Su Qin Peh Ewa Kosior-Jarecka Urszula Lukasik Mandy Krumbiegel Eranga N Vithana Tien Yin Wong Yutao Liu Allison E Ashley Koch Pratap Challa Robyn M Rautenbach David A Mackey Alex W Hewitt Paul Mitchell Jie Jin Wang Ari Ziskind Trevor Carmichael Rangappa Ramakrishnan Kalpana Narendran Rangaraj Venkatesh Saravanan Vijayan Peiquan Zhao Xueyi Chen Dalia Guadarrama-Vallejo Ching Yu Cheng Shamira A Perera Rahat Husain Su-Ling Ho Ulrich-Christoph Welge-Luessen Christian Mardin Ursula Schloetzer-Schrehardt Axel M Hillmer Stefan Herms Susanne Moebus Markus M Nöthen Nicole Weisschuh Rohit Shetty Arkasubhra Ghosh Yik Ying Teo Matthew A Brown Ignacio Lischinsky Jonathan G Crowston Michael Coote Bowen Zhao Jinghong Sang Nihong Zhang Qisheng You Vera Vysochinskaya Panayiota Founti Anthoula Chatzikyriakidou Alexandros Lambropoulos Eleftherios Anastasopoulos Anne L Coleman M Roy Wilson Douglas J Rhee Jae Hee Kang Inna May-Bolchakova Steffen Heegaard Kazuhiko Mori Wallace L M Alward Jost B Jonas Liang Xu Jeffrey M Liebmann Balram Chowbay Elke Schaeffeler Matthias Schwab Fabian Lerner Ningli Wang Zhenglin Yang Paolo Frezzotti Shigeru Kinoshita John H Fingert Masaru Inatani Kei Tashiro André Reis Deepak P Edward Louis R Pasquale Toshiaki Kubota Janey L Wiggs Francesca Pasutto Fotis Topouzis Michael Dubina Jamie E Craig Nagahisa Yoshimura Periasamy Sundaresan Simon W M John Robert Ritch Michael A Hauser Chiea-Chuen Khor

Nat Genet 2015 Apr 23;47(4):387-92. Epub 2015 Feb 23.

1] Singapore Eye Research Institute, Singapore. [2] Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. [3] Division of Human Genetics, Genome Institute of Singapore, Singapore.

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http://dx.doi.org/10.1038/ng.3226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605818PMC
April 2015

Derivation of mesenchymal stromal cells from pluripotent stem cells through a neural crest lineage using small molecule compounds with defined media.

PLoS One 2014 2;9(12):e112291. Epub 2014 Dec 2.

Department of Tissue Regeneration, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan; Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251837PMC
August 2015

Optimal dose-setting study of curcumin for improvement of left ventricular systolic function after myocardial infarction in rats.

J Pharmacol Sci 2014 19;126(4):329-36. Epub 2014 Nov 19.

Division of Molecular Medicine, School of Pharmaceutical Sciences, University of Shizuoka, 52-1, Yata, Suruga-ku, Shizuoka 422-8526, Japan; Shizuoka General Hospital, 4-27-1, Kitaando, Aoi-ku, Shizuoka 420-8527, Japan; Division of Translational Research, Clinical Research Institute, Kyoto Medical Center, National Hospital Organization, 1-1, Mukaihata-cho, Fukakusa, Fushimi-ku, Kyoto 612-8555, Japan.

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http://dx.doi.org/10.1254/jphs.14151FPDOI Listing
August 2015

Cell surface markers of functional phenotypic corneal endothelial cells.

Invest Ophthalmol Vis Sci 2014 Nov 11;55(11):7610-8. Epub 2014 Nov 11.

Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.

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http://dx.doi.org/10.1167/iovs.14-14980DOI Listing
November 2014

New therapeutic modality for corneal endothelial disease using Rho-associated kinase inhibitor eye drops.

Cornea 2014 Nov;33 Suppl 11:S25-31

*Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan; and †Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1097/ICO.0000000000000240DOI Listing
November 2014

Three-dimensional architecture of collagen type VI in the human trabecular meshwork.

Mol Vis 2014 13;20:638-48. Epub 2014 May 13.

Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Wales, UK.

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September 2014

Effects of long-term topical prostaglandin therapy on central corneal thickness.

J Ocul Pharmacol Ther 2014 Jun 16;30(5):440-4. Epub 2014 Apr 16.

Department of Ophthalmology, Kyoto Prefectural University of Medicine , Kyoto, Japan .

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http://dx.doi.org/10.1089/jop.2013.0196DOI Listing
June 2014

Morphological analysis of age-related iridocorneal angle changes in normal and glaucomatous cases using anterior segment optical coherence tomography.

Clin Ophthalmol 2014 21;8:113-8. Epub 2013 Dec 21.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.2147/OPTH.S52370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873234PMC
December 2013

Involvement of cyclin D and p27 in cell proliferation mediated by ROCK inhibitors Y-27632 and Y-39983 during corneal endothelium wound healing.

Invest Ophthalmol Vis Sci 2014 Jan 15;55(1):318-29. Epub 2014 Jan 15.

Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.

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http://dx.doi.org/10.1167/iovs.13-12225DOI Listing
January 2014

Rho-associated kinase inhibitor eye drop treatment as a possible medical treatment for Fuchs corneal dystrophy.

Cornea 2013 Aug;32(8):1167-70

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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August 2013

The ROCK inhibitor eye drop accelerates corneal endothelium wound healing.

Invest Ophthalmol Vis Sci 2013 Apr 3;54(4):2493-502. Epub 2013 Apr 3.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.12-11320DOI Listing
April 2013

A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma.

Mol Vis 2012 27;18:1727-39. Epub 2012 Jun 27.

Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Kyoto, Japan.

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November 2012

ROCK inhibitor converts corneal endothelial cells into a phenotype capable of regenerating in vivo endothelial tissue.

Am J Pathol 2012 Jul 14;181(1):268-77. Epub 2012 Jun 14.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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July 2012

The new therapeutic concept of using a rho kinase inhibitor for the treatment of corneal endothelial dysfunction.

Cornea 2011 Oct;30 Suppl 1:S54-9

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1097/ICO.0b013e3182281ee1DOI Listing
October 2011

Enhancement of corneal endothelium wound healing by Rho-associated kinase (ROCK) inhibitor eye drops.

Br J Ophthalmol 2011 Jul 11;95(7):1006-9. Epub 2011 Mar 11.

Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Tatara, Kyotanabe 610-0321, Japan.

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http://dx.doi.org/10.1136/bjo.2010.194571DOI Listing
July 2011

Enhancement on primate corneal endothelial cell survival in vitro by a ROCK inhibitor.

Invest Ophthalmol Vis Sci 2009 Aug 22;50(8):3680-7. Epub 2009 Apr 22.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.08-2634DOI Listing
August 2009

A ROCK inhibitor permits survival of dissociated human embryonic stem cells.

Nat Biotechnol 2007 Jun 27;25(6):681-6. Epub 2007 May 27.

Organogenesis and Neurogenesis Group, Center for Developmental Biology, RIKEN, Kobe 650-0047, Japan.

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http://dx.doi.org/10.1038/nbt1310DOI Listing
June 2007

Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix.

Proc Natl Acad Sci U S A 2006 Jun 9;103(25):9554-9. Epub 2006 Jun 9.

Organogenesis and Neurogenesis Group, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo, Kobe 650-0047, Japan.

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http://dx.doi.org/10.1073/pnas.0600104103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1480445PMC
June 2006

Gene disruption/knock-in analysis of mONT3: vector construction by employing both in vivo and in vitro recombinations.

Int J Dev Biol 2005 ;49(7):807-23

Organogenesis and Neurogenesis Group, Center for Developmental Biology, RIKEN, Kobe, Japan.

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January 2006