Monte Westerfield

Monte Westerfield

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Monte Westerfield

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Cog4 is required for protrusion and extension of the epithelium in the developing semicircular canals.

Mech Dev 2019 02 1;155:1-7. Epub 2018 Oct 1.

Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mod.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226009PMC
February 2019

Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease.

N Engl J Med 2018 11 10;379(22):2131-2139. Epub 2018 Oct 10.

From Harvard Medical School (K.S., C.E., I.S.K., J.L., A.T.M., D.A.S.), Brigham and Women's Hospital (J.L.), and Massachusetts General Hospital (D.A.S.) - all in Boston; the National Institutes of Health Clinical Center (D.R.A., W.A.G., J.J.M., C.J.T.) and the National Human Genome Research Institute (A.L.W.), Bethesda, and the University of Maryland, College Park (A.M.C.-J., B.K., L.P.) - all in Maryland; Baylor College of Medicine, Houston (C.A.B., H.J.B., C.M.E., B.H.L., X.L., M.F.W., S.Y.); Stanford University, Stanford (J.A.B., C.R., M.T.W., E.A.A.), and the University of California, Los Angeles, Los Angeles (S.F.N., C.G.S.P.) - both in California; Vanderbilt University, Nashville (R.H., J.A.P.); HudsonAlpha Institute for Biotechnology, Huntsville, AL (H.J.J., E.A.W.); Oregon Health and Science University, Portland (D.M.K.); the Pacific Northwest National Laboratory, Richland, WA (T.O.M.); the University of Oregon, Eugene (J.H.P., M.W.); and Duke University, Durham, NC (V.S., N.M.W.).

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http://www.nejm.org/doi/10.1056/NEJMoa1714458
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http://dx.doi.org/10.1056/NEJMoa1714458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481166PMC
November 2018

Usherin defects lead to early-onset retinal dysfunction in zebrafish.

Exp Eye Res 2018 08 16;173:148-159. Epub 2018 May 16.

Department of Otorhinolaryngology, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands; Donders Institute for Brain, Cognition, and Behavior, Montessorilaan 3, 6525 HR Nijmegen, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144835183024
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http://dx.doi.org/10.1016/j.exer.2018.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054812PMC
August 2018

Model organism databases.

Genesis 2015 Aug;53(8):449

Institute of Neuroscience, 1254 University of Oregon, Eugene, OR, 97403-1254, USA.

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http://dx.doi.org/10.1002/dvg.22882DOI Listing
August 2015

Zebrafish models in translational research: tipping the scales toward advancements in human health.

Dis Model Mech 2014 Jul;7(7):739-43

Institute of Neuroscience, 1254 University of Oregon, Eugene OR 97403-1254, USA.

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http://dx.doi.org/10.1242/dmm.015545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073263PMC
July 2014

The zebrafish anatomy and stage ontologies: representing the anatomy and development of Danio rerio.

J Biomed Semantics 2014 Feb 25;5(1):12. Epub 2014 Feb 25.

ZFIN, 5291 University of Oregon, Eugene, OR 97403-5291, USA.

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http://dx.doi.org/10.1186/2041-1480-5-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944782PMC
February 2014

The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data.

Nucleic Acids Res 2014 Jan 11;42(Database issue):D966-74. Epub 2013 Nov 11.

Institute for Medical Genetics and Human Genetics, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany, Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany, Lawrence Berkeley National Laboratory, Mail Stop 84R0171, Berkeley, CA 94720, USA, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK, Department of Medical Genetics, Cambridge University Addenbrooke's Hospital, Cambridge CB2 2QQ, UK, Université Paul Sabatier, Faculté de Chirurgie Dentaire, CHU Toulouse, France, Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Sciences Centre (MAHSC), Manchester, UK, Centre for Genomic Medicine, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, MAHSC, Manchester M13 9WL, UK, Institute of Genetic Medicine. Newcastle University, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK, Department of Computer Science, University of Toronto, Ontario, Canada, Centre for Computational Medicine, Hospital for Sick Children, Toronto, Ontario, Canada, Department of Clinical Genetics, Leeds Teaching Hospitals NHS Trust, Leeds LS2 9NS, UK, MRC Human Genetics Unit, MRC Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK, The Jackson Laboratory, Bar Harbor, ME 04609, USA, Center for Molecular and Vascular Biology, University of Leuven, Belgium, Department of Neuropediatrics, University Medical Center Schleswig-Holstein, Kiel Campus, 24105 Kiel, Germany, NE Thames Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK, Drexel University College of Medicine, Philadelphia, PA 19102, USA, Department of Haematology, University of Cambridge and NHS Blood and Transplant Cambridge, CB2 0PT Cambridge, UK, Autism and Developmental Medicine Institute, Geisinger Health System

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http://dx.doi.org/10.1093/nar/gkt1026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965098PMC
January 2014

The cone-dominant retina and the inner ear of zebrafish express the ortholog of CLRN1, the causative gene of human Usher syndrome type 3A.

Gene Expr Patterns 2013 Dec 14;13(8):473-81. Epub 2013 Sep 14.

Institute of Neuroscience, 1254 University of Oregon, Eugene, OR 97403-1254, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gep.2013.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888827PMC
December 2013

PhenoDigm: analyzing curated annotations to associate animal models with human diseases.

Database (Oxford) 2013 9;2013:bat025. Epub 2013 May 9.

Mouse Informatics Group, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.

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http://dx.doi.org/10.1093/database/bat025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649640PMC
October 2013

The zebrafish reference genome sequence and its relationship to the human genome.

Authors:
Kerstin Howe Matthew D Clark Carlos F Torroja James Torrance Camille Berthelot Matthieu Muffato John E Collins Sean Humphray Karen McLaren Lucy Matthews Stuart McLaren Ian Sealy Mario Caccamo Carol Churcher Carol Scott Jeffrey C Barrett Romke Koch Gerd-Jörg Rauch Simon White William Chow Britt Kilian Leonor T Quintais José A Guerra-Assunção Yi Zhou Yong Gu Jennifer Yen Jan-Hinnerk Vogel Tina Eyre Seth Redmond Ruby Banerjee Jianxiang Chi Beiyuan Fu Elizabeth Langley Sean F Maguire Gavin K Laird David Lloyd Emma Kenyon Sarah Donaldson Harminder Sehra Jeff Almeida-King Jane Loveland Stephen Trevanion Matt Jones Mike Quail Dave Willey Adrienne Hunt John Burton Sarah Sims Kirsten McLay Bob Plumb Joy Davis Chris Clee Karen Oliver Richard Clark Clare Riddle David Elliot David Eliott Glen Threadgold Glenn Harden Darren Ware Sharmin Begum Beverley Mortimore Beverly Mortimer Giselle Kerry Paul Heath Benjamin Phillimore Alan Tracey Nicole Corby Matthew Dunn Christopher Johnson Jonathan Wood Susan Clark Sarah Pelan Guy Griffiths Michelle Smith Rebecca Glithero Philip Howden Nicholas Barker Christine Lloyd Christopher Stevens Joanna Harley Karen Holt Georgios Panagiotidis Jamieson Lovell Helen Beasley Carl Henderson Daria Gordon Katherine Auger Deborah Wright Joanna Collins Claire Raisen Lauren Dyer Kenric Leung Lauren Robertson Kirsty Ambridge Daniel Leongamornlert Sarah McGuire Ruth Gilderthorp Coline Griffiths Deepa Manthravadi Sarah Nichol Gary Barker Siobhan Whitehead Michael Kay Jacqueline Brown Clare Murnane Emma Gray Matthew Humphries Neil Sycamore Darren Barker David Saunders Justene Wallis Anne Babbage Sian Hammond Maryam Mashreghi-Mohammadi Lucy Barr Sancha Martin Paul Wray Andrew Ellington Nicholas Matthews Matthew Ellwood Rebecca Woodmansey Graham Clark James D Cooper James Cooper Anthony Tromans Darren Grafham Carl Skuce Richard Pandian Robert Andrews Elliot Harrison Andrew Kimberley Jane Garnett Nigel Fosker Rebekah Hall Patrick Garner Daniel Kelly Christine Bird Sophie Palmer Ines Gehring Andrea Berger Christopher M Dooley Zübeyde Ersan-Ürün Cigdem Eser Horst Geiger Maria Geisler Lena Karotki Anette Kirn Judith Konantz Martina Konantz Martina Oberländer Silke Rudolph-Geiger Mathias Teucke Christa Lanz Günter Raddatz Kazutoyo Osoegawa Baoli Zhu Amanda Rapp Sara Widaa Cordelia Langford Fengtang Yang Stephan C Schuster Nigel P Carter Jennifer Harrow Zemin Ning Javier Herrero Steve M J Searle Anton Enright Robert Geisler Ronald H A Plasterk Charles Lee Monte Westerfield Pieter J de Jong Leonard I Zon John H Postlethwait Christiane Nüsslein-Volhard Tim J P Hubbard Hugues Roest Crollius Jane Rogers Derek L Stemple

Nature 2013 Apr 17;496(7446):498-503. Epub 2013 Apr 17.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature12111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703927PMC
April 2013

Dcc regulates asymmetric outgrowth of forebrain neurons in zebrafish.

PLoS One 2012 14;7(5):e36516. Epub 2012 May 14.

Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036516PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351449PMC
October 2012

500,000 fish phenotypes: The new informatics landscape for evolutionary and developmental biology of the vertebrate skeleton.

J Appl Ichthyol 2012 Jun 21;28(3):300-305. Epub 2012 May 21.

Department of Biology, 414 East Clark Street, University of South Dakota, Vermillion, South Dakota, United States of America.

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http://dx.doi.org/10.1111/j.1439-0426.2012.01985.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377363PMC
June 2012

MouseFinder: Candidate disease genes from mouse phenotype data.

Hum Mutat 2012 May 16;33(5):858-66. Epub 2012 Mar 16.

Vertebrate Genomics Team, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.

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http://doi.wiley.com/10.1002/humu.22051
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http://dx.doi.org/10.1002/humu.22051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327758PMC
May 2012

The zebrafish. Preface.

Methods Cell Biol 2011 ;105:xxi-xxii

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http://dx.doi.org/10.1016/b978-0-12-381320-6.00027-8DOI Listing
January 2012

Characterization and management of asymptomatic Mycobacterium infections at the Zebrafish International Resource Center.

J Am Assoc Lab Anim Sci 2011 Sep;50(5):675-9

Zebrafish International Resource Center, University of Oregon, Eugene, OR, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189671PMC
September 2011

Pineal-specific agouti protein regulates teleost background adaptation.

Proc Natl Acad Sci U S A 2010 Nov 27;107(47):20164-71. Epub 2010 Oct 27.

Department of Molecular Physiology and Biophysics, The Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1014941107
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http://dx.doi.org/10.1073/pnas.1014941107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996689PMC
November 2010

Whole-body cortisol response of zebrafish to acute net handling stress.

Aquaculture 2009 Dec;297(1-4):157-162

Oregon Cooperative Fish and Wildlife Research Unit, U.S. Geological Survey and Department of Fisheries and Wildlife, 104 Nash Hall, Oregon State University, Corvallis, OR 97331-3803, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289633PMC
http://dx.doi.org/10.1016/j.aquaculture.2009.08.035DOI Listing
December 2009

Linking human diseases to animal models using ontology-based phenotype annotation.

PLoS Biol 2009 Nov 24;7(11):e1000247. Epub 2009 Nov 24.

Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.

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http://dx.doi.org/10.1371/journal.pbio.1000247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774506PMC
November 2009

Emx3 is required for the differentiation of dorsal telencephalic neurons.

Dev Dyn 2009 Aug;238(8):1984-98

Institute of Developmental Biology, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/dvdy.22031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975037PMC
August 2009

Cryopreservation and in vitro fertilization at the zebrafish international resource center.

Methods Mol Biol 2009 ;546:45-65

Zebrafish International Resource Center, University of Oregon, Eugene, OR, USA.

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http://dx.doi.org/10.1007/978-1-60327-977-2_4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737363PMC
June 2009

Identification of differentially expressed genes in the zebrafish hypothalamic-pituitary axis.

Gene Expr Patterns 2009 Apr 8;9(4):200-8. Epub 2009 Jan 8.

Institute of Neuroscience, 1254 University of Oregon, Eugene, OR 97403, USA.

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http://dx.doi.org/10.1016/j.gep.2008.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804439PMC
April 2009

Lbx2 regulates formation of myofibrils.

BMC Dev Biol 2009 Feb 12;9:13. Epub 2009 Feb 12.

Institute of Neuroscience, University of Oregon, Eugene, OR 97403-1254, USA.

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http://dx.doi.org/10.1186/1471-213X-9-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656488PMC
February 2009

Sparc (Osteonectin) functions in morphogenesis of the pharyngeal skeleton and inner ear.

Matrix Biol 2008 Jul 15;27(6):561-72. Epub 2008 Mar 15.

Center of Marine Biotechnology, University of Maryland Biotechnology Institute, Baltimore, MD 21202, USA.

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http://dx.doi.org/10.1016/j.matbio.2008.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642737PMC
July 2008

Notch signaling regulates endocrine cell specification in the zebrafish anterior pituitary.

Dev Biol 2008 Jul 25;319(2):248-57. Epub 2008 Apr 25.

Laboratory of Molecular Genetics, NICHD, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ydbio.2008.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178411PMC
July 2008

Smarcd3 regulates the timing of zebrafish myogenesis onset.

J Biol Chem 2008 Feb 3;283(6):3529-36. Epub 2007 Dec 3.

Institute of Neuroscience, University of Oregon, Eugene, Oregon 97403-1254, USA.

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http://dx.doi.org/10.1074/jbc.M708594200DOI Listing
February 2008

Connecting evolutionary morphology to genomics using ontologies: a case study from Cypriniformes including zebrafish.

J Exp Zool B Mol Dev Evol 2007 Sep;308(5):655-68

Department of Biology, University of South Dakota, Vermillion, South Dakota 57069, USA.

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http://dx.doi.org/10.1002/jez.b.21181DOI Listing
September 2007

Phenotype ontologies: the bridge between genomics and evolution.

Trends Ecol Evol 2007 Jul 9;22(7):345-50. Epub 2007 Apr 9.

Department of Biology, University of South Dakota, Vermillion, SD 57069, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016953470700104
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http://dx.doi.org/10.1016/j.tree.2007.03.013DOI Listing
July 2007

Changes in retinoic acid signaling alter otic patterning.

Development 2007 Jul 23;134(13):2449-58. Epub 2007 May 23.

Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA.

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http://dx.doi.org/10.1242/dev.000448DOI Listing
July 2007

Caveolin-1 is required for lateral line neuromast and notochord development.

J Cell Sci 2007 Jul 5;120(Pt 13):2151-61. Epub 2007 Jun 5.

Institute for Molecular Bioscience, University of Queensland, Brisbane 4072, Australia.

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http://dx.doi.org/10.1242/jcs.003830DOI Listing
July 2007

Multiple upstream modules regulate zebrafish myf5 expression.

BMC Dev Biol 2007 Jan 3;7. Epub 2007 Jan 3.

Graduate Institute of Life Sciences, Tamkang University, Tamsui, Taiwan.

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http://dx.doi.org/10.1186/1471-213X-7-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769357PMC
January 2007

Signaling networks that regulate muscle development: lessons from zebrafish.

Dev Growth Differ 2007 Jan;49(1):1-11

Institute of Neuroscience, University of Oregon, Eugene, OR 97403-1254, USA.

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http://dx.doi.org/10.1111/j.1440-169X.2007.00905.xDOI Listing
January 2007

Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b.

BMC Dev Biol 2007 Jan 19;7. Epub 2007 Jan 19.

Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA.

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http://bmcdevbiol.biomedcentral.com/articles/10.1186/1471-21
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http://dx.doi.org/10.1186/1471-213X-7-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794237PMC
January 2007

Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened.

Dev Biol 2006 Sep 6;297(1):127-40. Epub 2006 May 6.

Institute of Neuroscience, University of Oregon, Eugene, OR 97403-1254, USA.

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http://dx.doi.org/10.1016/j.ydbio.2006.05.001DOI Listing
September 2006

Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists.

Development 2006 Aug 19;133(16):3191-200. Epub 2006 Jul 19.

Institute of Neuroscience, University of Oregon, Eugene, OR 97403-1254, USA.

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http://dx.doi.org/10.1242/dev.02485DOI Listing
August 2006

Zebrafish as a model for caveolin-associated muscle disease; caveolin-3 is required for myofibril organization and muscle cell patterning.

Hum Mol Genet 2005 Jul 11;14(13):1727-43. Epub 2005 May 11.

Institute for Molecular Bioscience, Universitky of Queensland, Brisbane 4072, Australia.

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http://dx.doi.org/10.1093/hmg/ddi179DOI Listing
July 2005

pitx3 defines an equivalence domain for lens and anterior pituitary placode.

Development 2005 Apr 23;132(7):1579-90. Epub 2005 Feb 23.

Department of Developmental Biology, University Freiburg, Germany.

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http://dev.biologists.org/cgi/doi/10.1242/dev.01723
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http://dx.doi.org/10.1242/dev.01723DOI Listing
April 2005

Combined haploid and insertional mutation screen in the zebrafish.

Genesis 2004 Dec;40(4):231-40

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1002/gene.20090DOI Listing
December 2004

Hedgehog signaling is required for commitment but not initial induction of slow muscle precursors.

Dev Biol 2004 Nov;275(1):143-57

Institute of Neuroscience, University of Oregon, Eugene, OR 97403-1254, USA.

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http://dx.doi.org/10.1016/j.ydbio.2004.07.030DOI Listing
November 2004

Pax8 and Pax2a function synergistically in otic specification, downstream of the Foxi1 and Dlx3b transcription factors.

Development 2004 Oct;131(20):5091-102

Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA.

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http://dx.doi.org/10.1242/dev.01346DOI Listing
October 2004

GSD: a genetic screen database.

Mech Dev 2004 Jul;121(7-8):959-63

European Molecular Biology Laboratory-Heidelberg, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.mod.2004.02.006DOI Listing
July 2004

Zebrafish mosaic eyes is a novel FERM protein required for retinal lamination and retinal pigmented epithelial tight junction formation.

Curr Biol 2004 Apr;14(8):711-7

Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA.

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http://dx.doi.org/10.1016/j.cub.2004.04.006DOI Listing
April 2004

Fgf3 and Fgf8 dependent and independent transcription factors are required for otic placode specification.

Development 2003 May;130(10):2213-24

Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA. Gene Tools, LLC, 1 Summerton Way, Philomath, OR 97370, USA.

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http://dx.doi.org/10.1242/dev.00445DOI Listing
May 2003

The Zebrafish Information Network (ZFIN): the zebrafish model organism database.

Nucleic Acids Res 2003 Jan;31(1):241-3

The Zebrafish International Resource Center, University of Oregon, Eugene, OR 97403-5274, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC165474PMC
http://dx.doi.org/10.1093/nar/gkg027DOI Listing
January 2003