Monte M Winslow

Monte M Winslow

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Monte M Winslow

Monte M Winslow

Publications by authors named "Monte M Winslow"

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An LKB1-SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation.

Cancer Discov 2019 Nov 26;9(11):1590-1605. Epub 2019 Jul 26.

Cancer Biology Program, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1158/2159-8290.CD-18-1237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825558PMC
November 2019

Towards quantitative and multiplexed in vivo functional cancer genomics.

Nat Rev Genet 2018 12;19(12):741-755

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://www.nature.com/articles/s41576-018-0053-7
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http://dx.doi.org/10.1038/s41576-018-0053-7DOI Listing
December 2018

Publisher Correction: Towards quantitative and multiplexed in vivo functional cancer genomics.

Nat Rev Genet 2018 Dec;19(12):801

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://www.nature.com/articles/s41576-018-0062-6
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http://dx.doi.org/10.1038/s41576-018-0062-6DOI Listing
December 2018

Tumor Suppressor Activity of Selenbp1, a Direct Nkx2-1 Target, in Lung Adenocarcinoma.

Mol Cancer Res 2018 11 12;16(11):1737-1749. Epub 2018 Jul 12.

Cancer Biology Program, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-0392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541221PMC
November 2018

Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance.

Sci Rep 2018 09 18;8(1):14008. Epub 2018 Sep 18.

Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1038/s41598-018-32159-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143627PMC
September 2018

A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo.

Nat Methods 2017 Jul 22;14(7):737-742. Epub 2017 May 22.

Department of Genetics, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/nmeth.4297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495136PMC
July 2017

Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility.

Cell 2016 Jul 30;166(2):328-342. Epub 2016 Jun 30.

Cancer Biology Program, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.05.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004630PMC
July 2016

An Arntl2-Driven Secretome Enables Lung Adenocarcinoma Metastatic Self-Sufficiency.

Cancer Cell 2016 05 14;29(5):697-710. Epub 2016 Apr 14.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Cancer Biology Program, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864124PMC
May 2016

Recombinase-based conditional and reversible gene regulation via XTR alleles.

Nat Commun 2015 Nov 5;6:8783. Epub 2015 Nov 5.

Department of Cancer Biology, Abramson Family Cancer Research Institute and Perelman School of Medicine at the University of Pennsylvania, 421 Curie Boulevard, 751 Biomedical Research Building II/III, Philadelphia, Pennsylvania 19004, USA.

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http://dx.doi.org/10.1038/ncomms9783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635517PMC
November 2015

Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2.

PLoS Genet 2015 Aug 5;11(8):e1005408. Epub 2015 Aug 5.

Division of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America; Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526516PMC
August 2015

Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.

Genes Dev 2015 Jul 15;29(14):1576-85. Epub 2015 Jul 15.

Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA; Cancer Biology Program, Stanford University School of Medicine, Stanford, California 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1101/gad.264861.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526740PMC
July 2015

An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.

Mol Cell 2014 Aug 17;55(3):436-50. Epub 2014 Jul 17.

Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151130PMC
August 2014

Obligate progression precedes lung adenocarcinoma dissemination.

Cancer Discov 2014 Jul 16;4(7):781-9. Epub 2014 Apr 16.

Authors' Affiliations:Cancer Biology Program; Departments of Genetics and Pathology; and Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California; and

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http://dx.doi.org/10.1158/2159-8290.CD-13-0862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090265PMC
July 2014

Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.

Proc Natl Acad Sci U S A 2014 Jul 30;111(28):10299-304. Epub 2014 Jun 30.

Stem Cell Program, Boston Children's Hospital, Boston MA 02115;Harvard Stem Cell Institute, Cambridge, MA 02138;Department of Genetics, Harvard Medical School, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1404399111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104911PMC
July 2014

A conditional system to specifically link disruption of protein-coding function with reporter expression in mice.

Cell Rep 2014 Jun 12;7(6):2078-86. Epub 2014 Jun 12.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305-5120, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305-5324, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305-5456, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.05.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113058PMC
June 2014

HMGA2 functions as a competing endogenous RNA to promote lung cancer progression.

Nature 2014 Jan 4;505(7482):212-7. Epub 2013 Dec 4.

1] Signal Transduction Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3LY, UK [2] Lung Cancer Group, Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

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http://dx.doi.org/10.1038/nature12785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886898PMC
January 2014

Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma.

Genes Dev 2013 Jul;27(14):1557-67

David H. Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1101/gad.222745.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731545PMC
July 2013

Characterizing deformability and surface friction of cancer cells.

Proc Natl Acad Sci U S A 2013 May 22;110(19):7580-5. Epub 2013 Apr 22.

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1073/pnas.1218806110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651488PMC
May 2013

Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1).

J Biol Chem 2012 Aug 2;287(34):28790-801. Epub 2012 Jul 2.

Department of Pathology, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania 17033, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M112.367987
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http://dx.doi.org/10.1074/jbc.M112.367987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436544PMC
August 2012

Treating metastatic cancer with nanotechnology.

Nat Rev Cancer 2011 Dec 23;12(1):39-50. Epub 2011 Dec 23.

David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1038/nrc3180DOI Listing
December 2011

Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma.

Cancer Discov 2011 Aug 16;1(3):236-47. Epub 2011 Jun 16.

Koch Institute for Integrative Cancer Research, Department of Biology, and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160630PMC
August 2011

Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress.

Proc Natl Acad Sci U S A 2011 May 9;108(21):8773-8. Epub 2011 May 9.

Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1105941108
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http://dx.doi.org/10.1073/pnas.1105941108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102385PMC
May 2011

Endogenous T cell responses to antigens expressed in lung adenocarcinomas delay malignant tumor progression.

Cancer Cell 2011 Jan;19(1):72-85

Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.ccr.2010.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069809PMC
January 2011

Stage-specific sensitivity to p53 restoration during lung cancer progression.

Nature 2010 Nov;468(7323):572-5

Koch Institute for Integrative Cancer Research, Department of Biology, and Howard Hughes Medical Institute, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

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http://www.nature.com/doifinder/10.1038/nature09535
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http://dx.doi.org/10.1038/nature09535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003305PMC
November 2010

Selective role of calcineurin in haematopoiesis and lymphopoiesis.

EMBO Rep 2008 Nov 26;9(11):1141-8. Epub 2008 Sep 26.

Multidisciplinary Program in Immunology, Stanford University, Stanford, California, USA

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http://dx.doi.org/10.1038/embor.2008.174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581854PMC
November 2008

Calcineurin sets the bandwidth for discrimination of signals during thymocyte development.

Nature 2007 Nov;450(7170):731-5

Howard Hughes Medical Institute and the Department of Pathology, Stanford University, Stanford, California 94305, USA.

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http://www.nature.com/articles/nature06305
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http://dx.doi.org/10.1038/nature06305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336393PMC
November 2007

Selective role of NFATc3 in positive selection of thymocytes.

J Immunol 2007 Jul;179(1):103-10

Departments of Developmental Biology and Pathology, Howard Hughes Medical Institute, Stanford University, 279 Campus Drive, Stanford, CA 94305, USA.

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http://dx.doi.org/10.4049/jimmunol.179.1.103DOI Listing
July 2007

Enhanced NFATc1 nuclear occupancy causes T cell activation independent of CD28 costimulation.

J Immunol 2007 Apr;178(7):4315-21

Division of Oncology, Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.4049/jimmunol.178.7.4315DOI Listing
April 2007

Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function.

Nature 2006 Sep;443(7109):345-9

Department of Developmental Biology, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature05097DOI Listing
September 2006

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.

Nature 2006 Jun 22;441(7093):595-600. Epub 2006 Mar 22.

Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature04678DOI Listing
June 2006

Calcineurin/NFAT signaling in osteoblasts regulates bone mass.

Dev Cell 2006 Jun;10(6):771-82

Program in Immunology, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1016/j.devcel.2006.04.006DOI Listing
June 2006

CD8+ recent thymic emigrants home to and efficiently repopulate the small intestine epithelium.

Nat Immunol 2006 May 2;7(5):482-8. Epub 2006 Apr 2.

Program in Immunology, Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/ni1319DOI Listing
May 2006

Thymocyte negative selection is mediated by protein kinase C- and Ca2+-dependent transcriptional induction of bim [corrected].

J Immunol 2006 Feb;176(4):2299-306

Department of Developmental Biology, Howard Hughes Medical Institute, Stanford University, CA 94305, USA.

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http://dx.doi.org/10.4049/jimmunol.176.4.2299DOI Listing
February 2006

The calcineurin phosphatase complex modulates immunogenic B cell responses.

Immunity 2006 Feb;24(2):141-52

Program in Immunology, Stanford University, Stanford, California 94305, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S107476130600005
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http://dx.doi.org/10.1016/j.immuni.2005.12.013DOI Listing
February 2006

Immunology. Decoding calcium signaling.

Science 2005 Jan;307(5706):56-7

Immunology Program, Stanford University, Stanford, CA 94305, USA

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http://dx.doi.org/10.1126/science.1108163DOI Listing
January 2005

Calcineurin B1 is essential for positive but not negative selection during thymocyte development.

Immunity 2004 Mar;20(3):255-66

Department of Microbiology and Immunology, Beckman Center, Room B211, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/s1074-7613(04)00052-4DOI Listing
March 2004

Calcium signalling in lymphocytes.

Curr Opin Immunol 2003 Jun;15(3):299-307

Program in Immunology and the Howard Hughes Medical Institute, Stanford University, Stanford CA 94305, USA.

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http://dx.doi.org/10.1016/s0952-7915(03)00050-5DOI Listing
June 2003

Major histocompatibility complex class II presentation of cell-associated antigen is mediated by CD8alpha+ dendritic cells in vivo.

J Exp Med 2002 Mar;195(6):683-94

The Biomedical Research Centre, Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193737PMC
http://dx.doi.org/10.1084/jem.20010898DOI Listing
March 2002