Monique Stins

Monique Stins

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Monique Stins

Monique Stins

Publications by authors named "Monique Stins"

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The Evolving Concept of the Blood Brain Barrier (BBB): From a Single Static Barrier to a Heterogeneous and Dynamic Relay Center.

Front Cell Neurosci 2019 20;13:405. Epub 2019 Sep 20.

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.

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http://dx.doi.org/10.3389/fncel.2019.00405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763697PMC
September 2019

Brain vascular heterogeneity: implications for disease pathogenesis and design of in vitro blood-brain barrier models.

Fluids Barriers CNS 2018 Apr 23;15(1):12. Epub 2018 Apr 23.

Malaria Research Institute, Dept. Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, SPH East 4135, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1186/s12987-018-0097-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911972PMC
April 2018

Diverse functional outcomes of Plasmodium falciparum ligation of EPCR: potential implications for malarial pathogenesis.

Cell Microbiol 2015 Dec 20;17(12):1883-99. Epub 2015 Jul 20.

Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1111/cmi.12479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661070PMC
December 2015

Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant.

Thromb Haemost 2015 Nov 9;114(5):1038-48. Epub 2015 Jul 9.

Jens E. V. Petersen, Centre for Medical Parasitology, Dept. of International Health, Immunology & Microbiology, University of Copenhagen and Dept. of Infectious Diseases, Rigshospitalet, 1014 Copenhagen, Denmark, Tel.: +45 35327549, Fax: +45 35327851, E-mail:

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http://dx.doi.org/10.1160/TH15-01-0018DOI Listing
November 2015

CD68 acts as a major gateway for malaria sporozoite liver infection.

J Exp Med 2015 Aug 27;212(9):1391-403. Epub 2015 Jul 27.

W. Harry Feinstone Department of Molecular Microbiology and Immunology and Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health; and Department of Neurology, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, MD 21205 W. Harry Feinstone Department of Molecular Microbiology and Immunology and Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health; and Department of Neurology, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, MD 21205

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http://dx.doi.org/10.1084/jem.20110575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548058PMC
August 2015

Delivering minocycline into brain endothelial cells with liposome-based technology.

J Cereb Blood Flow Metab 2012 Jun 11;32(6):983-8. Epub 2012 Apr 11.

Departments of Radiology and Neurology, Neuroprotection Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.

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http://dx.doi.org/10.1038/jcbfm.2012.48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367232PMC
June 2012

How can microbial interactions with the blood-brain barrier modulate astroglial and neuronal function?

Cell Microbiol 2011 Oct 6;13(10):1470-8. Epub 2011 Sep 6.

Johns Hopkins SOM, Department Pathology, Division Medical Microbiology, 720 Rutland Ave, Ross 624, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1111/j.1462-5822.2011.01661.xDOI Listing
October 2011

Amelioration of inflammation and cytotoxicity by dipyridamole in brain endothelial cells.

Cerebrovasc Dis 2010 Aug 23;30(3):290-6. Epub 2010 Jul 23.

Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA.

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http://dx.doi.org/10.1159/000319072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214842PMC
August 2010

Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium.

Blood 2009 Nov 27;114(19):4243-52. Epub 2009 Aug 27.

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2009-06-22
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http://dx.doi.org/10.1182/blood-2009-06-226415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925626PMC
November 2009

Lithium upregulates vascular endothelial growth factor in brain endothelial cells and astrocytes.

Stroke 2009 Feb 30;40(2):652-5. Epub 2008 Oct 30.

Department of Radiology and Neurology, Neuroprotection Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.108.524504
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http://dx.doi.org/10.1161/STROKEAHA.108.524504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691992PMC
February 2009

Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia.

Stroke 2008 Sep 17;39(9):2538-43. Epub 2008 Jul 17.

Massachusetts General Hospital, Neuroprotection Research Laboratory, 149 13th Street, R. 2401, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1161/STROKEAHA.108.514927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754072PMC
September 2008

Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons.

Proc Natl Acad Sci U S A 2008 May 21;105(21):7582-7. Epub 2008 May 21.

Neuroprotection Research Laboratory, Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129.

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http://dx.doi.org/10.1073/pnas.0801105105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396701PMC
May 2008

Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity.

Antimicrob Agents Chemother 2007 Dec 17;51(12):4471-3. Epub 2007 Sep 17.

School of Biological and Chemical Sciences, Birkbeck College, University of London, London WC1E 7HX, England, United Kingdom.

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http://dx.doi.org/10.1128/AAC.00373-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168013PMC
December 2007

Balamuthia mandrillaris interactions with human brain microvascular endothelial cells in vitro.

J Med Microbiol 2007 Aug;56(Pt 8):1110-1115

School of Biological and Chemical Sciences, Birkbeck, University of London, London WC1E 7HX, UK.

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http://dx.doi.org/10.1099/jmm.0.47134-0DOI Listing
August 2007

Gp120-mediated cytotoxicity of human brain microvascular endothelial cells is dependent on p38 mitogen-activated protein kinase activation.

J Neurovirol 2007 Jun;13(3):242-51

Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1080/13550280701286531DOI Listing
June 2007

Plasmodium falciparum-infected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers.

J Infect Dis 2007 Apr 21;195(7):942-50. Epub 2007 Feb 21.

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1086/512083DOI Listing
April 2007

Effects of human serum on Balamuthia mandrillaris interactions with human brain microvascular endothelial cells.

J Med Microbiol 2007 Jan;56(Pt 1):30-35

School of Biological and Chemical Sciences, Birkbeck College, University of London, London WC1E 7HX, UK.

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http://dx.doi.org/10.1099/jmm.0.46847-0DOI Listing
January 2007

HIV-1 gp120 as well as alcohol affect blood-brain barrier permeability and stress fiber formation: involvement of reactive oxygen species.

Alcohol Clin Exp Res 2007 Jan;31(1):130-7

Department of Pediatrics, Division Infectious Diseases, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1111/j.1530-0277.2006.00271.xDOI Listing
January 2007

Use of in vitro assays to determine effects of human serum on biological characteristics of Acanthamoeba castellanii.

J Clin Microbiol 2006 Jul;44(7):2595-600

School of Biological and Chemical Sciences, Birkbeck, College University of London, London WC1E 7HX, England.

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http://dx.doi.org/10.1128/JCM.00144-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489474PMC
July 2006

Balamuthia mandrillaris exhibits metalloprotease activities.

FEMS Immunol Med Microbiol 2006 Jun;47(1):83-91

School of Biological and Chemical Sciences, Birkbeck College, University of London, London, UK.

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https://academic.oup.com/femspd/article-lookup/doi/10.1111/j
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http://dx.doi.org/10.1111/j.1574-695X.2006.00065.xDOI Listing
June 2006

Plasmodium falciparum-infected erythrocytes increase intercellular adhesion molecule 1 expression on brain endothelium through NF-kappaB.

Infect Immun 2006 Jun;74(6):3262-70

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 720 Rutland Avenue, Ross 1170, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1128/IAI.01625-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479273PMC
June 2006

Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity.

Nat Med 2006 Feb 29;12(2):207-13. Epub 2006 Jan 29.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, CRB-440, 1650 Orleans Street, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1038/nm1352DOI Listing
February 2006

CD4 and chemokine receptors on human brain microvascular endothelial cells, implications for human immunodeficiency virus type 1 pathogenesis.

Endothelium 2004 Sep-Dec;11(5-6):275-84

Division of Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1080/10623320490904179DOI Listing
May 2005

Acanthamoeba castellanii induces host cell death via a phosphatidylinositol 3-kinase-dependent mechanism.

Infect Immun 2005 May;73(5):2704-8

School of Biological and Chemical Sciences, Birkbeck, College, University of London, London WC1E 7HX, England, United Kingdom.

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http://iai.asm.org/cgi/doi/10.1128/IAI.73.5.2704-2708.2005
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http://dx.doi.org/10.1128/IAI.73.5.2704-2708.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087316PMC
May 2005

Borrelia burgdorferi, host-derived proteases, and the blood-brain barrier.

Infect Immun 2005 Feb;73(2):1014-22

Department of Pediatrics, The Johns Hopkins University School of Medicine, Park Building, Room 256, 600 North Wolfe Street, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1128/IAI.73.2.1014-1022.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC546937PMC
February 2005

CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer.

J Neuroimmunol 2004 Aug;153(1-2):150-7

Department of Neurosciences, Cleveland Clinic Foundation, NC 30 Lerner Research Institute, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.jneuroim.2004.05.004DOI Listing
August 2004

Acanthamoeba induces cell-cycle arrest in host cells.

J Med Microbiol 2004 Aug;53(Pt 8):711-717

School of Biological and Chemical Sciences, Birkbeck College, University of London, London WC1E 7HX, UK 2Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1099/jmm.0.45604-0DOI Listing
August 2004

Acanthamoeba interactions with human brain microvascular endothelial cells.

Microb Pathog 2003 Dec;35(6):235-41

School of Biological and Chemical Sciences, Birkbeck College, University of London, WC1E 7HX, England, London, UK.

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http://dx.doi.org/10.1016/j.micpath.2003.07.001DOI Listing
December 2003

Induction of intercellular adhesion molecule-1 on human brain endothelial cells by HIV-1 gp120: role of CD4 and chemokine coreceptors.

Lab Invest 2003 Dec;83(12):1787-98

Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1097/01.lab.0000107008.13321.c8DOI Listing
December 2003

Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells.

J Med Microbiol 2003 Nov;52(Pt 11):961-970

Divisions of Hematology-Oncology1 and Infectious Diseases3, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA 2The Johns Hopkins University, Pediatric Infectious Diseases, 600 N. Wolfe St, Park 256, Baltimore, MD 21287, USA 4Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA 5National Institute of Health Sciences, Tokyo, Japan.

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http://dx.doi.org/10.1099/jmm.0.05230-0DOI Listing
November 2003

Binding of Candida albicans enolase to plasmin(ogen) results in enhanced invasion of human brain microvascular endothelial cells.

J Med Microbiol 2003 Aug;52(Pt 8):615-622

Division of Hematology-Oncology, Mailstop 57, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA 2Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA 3,4Division of Infectious Diseases3 and Department of Surgery4, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1099/jmm.0.05060-0DOI Listing
August 2003

37-kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake.

J Biol Chem 2003 May 3;278(19):16857-62. Epub 2003 Mar 3.

Department of Pediatrics, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1074/jbc.M301028200DOI Listing
May 2003

The K1 capsule modulates trafficking of E. coli-containing vacuoles and enhances intracellular bacterial survival in human brain microvascular endothelial cells.

Cell Microbiol 2003 Apr;5(4):245-52

Division of Pediatrics Infectious Diseases, The Johns Hopkins University School of Medicine, Baltimore, MD 2128, USA.

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http://dx.doi.org/10.1046/j.1462-5822.2003.t01-1-00271.xDOI Listing
April 2003

Ceramide signaling in fenretinide-induced endothelial cell apoptosis.

J Biol Chem 2002 Dec 17;277(51):49531-7. Epub 2002 Oct 17.

Division of Hematology-Oncology, Department of Pediatrics, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1074/jbc.M209962200DOI Listing
December 2002

Transforming growth factor-beta increases Escherichia coli K1 adherence, invasion, and transcytosis in human brain microvascular endothelial cells.

Cell Tissue Res 2002 Aug 5;309(2):281-6. Epub 2002 Jul 5.

Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1007/s00441-002-0549-4DOI Listing
August 2002

alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin.

Int J Cancer 2002 Apr;98(5):690-7

Division of Hematology-Oncology, Department of Pediatrics, Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1002/ijc.10265DOI Listing
April 2002