Monique Howard

Monique Howard

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Monique Howard

Monique Howard

Publications by authors named "Monique Howard"

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Anti-PCSK9 antibody pharmacokinetics and low-density lipoprotein-cholesterol pharmacodynamics in nonhuman primates are antigen affinity-dependent and exhibit limited sensitivity to neonatal Fc receptor-binding enhancement.

J Pharmacol Exp Ther 2015 Apr 4;353(1):119-31. Epub 2015 Feb 4.

Departments of Pharmacokinetics and Drug Metabolism (K.R.H., K.C.M., M.W.R.), Metabolic Disorders (B.A., J.C.Y.C., S.M.J.), Therapeutic Discovery (M.H., W.W., J.S., J.H., J.T., C.K., D.E.P., R.R.K., M.L.M.), Molecular Sciences (R.X.), and Biostatistics (L.Z.), Amgen, South San Francisco, California.

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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.114.22124
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http://dx.doi.org/10.1124/jpet.114.221242DOI Listing
April 2015

Mutation of Gtf2ird1 from the Williams-Beuren syndrome critical region results in facial dysplasia, motor dysfunction, and altered vocalisations.

Neurobiol Dis 2012 Mar 11;45(3):913-22. Epub 2011 Dec 11.

Howard Florey Institute, Florey Neuroscience Institutes, University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.nbd.2011.12.010DOI Listing
March 2012

Plasma protein binding in drug discovery and development.

Comb Chem High Throughput Screen 2010 Feb;13(2):170-87

Amgen Inc., 1201 Amgen Court West, Seattle, WA 98119, USA.

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February 2010

Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease.

Hum Mol Genet 2009 Feb 13;18(4):753-66. Epub 2008 Nov 13.

Howard Florey Institute, University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1093/hmg/ddn385DOI Listing
February 2009

PLC-beta1 knockout mice as a model of disrupted cortical development and plasticity: behavioral endophenotypes and dysregulation of RGS4 gene expression.

Hippocampus 2008 ;18(8):824-34

Howard Florey Institute, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1002/hipo.20443DOI Listing
November 2008

Sex-specific behavioural effects of environmental enrichment in a transgenic mouse model of amyotrophic lateral sclerosis.

Eur J Neurosci 2008 Aug;28(4):717-23

Howard Florey Institute, and Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Vic 3010, Australia.

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http://dx.doi.org/10.1111/j.1460-9568.2008.06374.xDOI Listing
August 2008

Downregulation of uPAR confirms link in growth and metastasis of osteosarcoma.

Clin Exp Metastasis 2005 29;22(8):643-52. Epub 2006 Apr 29.

Department of Orthopaedics, The University of Melbourne, St. Vincent's Hospital Melbourne, P.O. Box 2900, 3065 Fitzroy, VIC, Australia.

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http://dx.doi.org/10.1007/s10585-006-9004-3DOI Listing
October 2006

Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine.

Eur J Neurosci 2005 Oct;22(8):2081-8

Howard Florey Institute, University of Melbourne, Parkville, VIC 3010, Australia.

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http://dx.doi.org/10.1111/j.1460-9568.2005.04365.xDOI Listing
October 2005

An in vivo model of prostate carcinoma growth and invasion in bone.

Cell Tissue Res 2002 Mar 14;307(3):337-45. Epub 2002 Feb 14.

Orthopaedic Department, St. Vincent's Hospital, Fitzroy, Australia.

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http://link.springer.com/content/pdf/10.1007/s00441-001-0503
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http://link.springer.com/10.1007/s00441-001-0503-x
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http://dx.doi.org/10.1007/s00441-001-0503-xDOI Listing
March 2002