Publications by authors named "Monica J Roth"

47Publications

X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition.

Proteins 2017 04 3;85(4):647-656. Epub 2017 Feb 3.

Center for Advanced Biotechnology and Medicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, 08854.

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http://dx.doi.org/10.1002/prot.25245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357174PMC
April 2017

Phosphorylation Requirement of Murine Leukemia Virus p12.

J Virol 2016 Dec 28;90(24):11208-11219. Epub 2016 Nov 28.

Rutgers-Robert Wood Johnson Medical School, Department of Pharmacology, Piscataway, New Jersey, USA

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http://dx.doi.org/10.1128/JVI.01178-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126377PMC
December 2016

Repression of the Chromatin-Tethering Domain of Murine Leukemia Virus p12.

J Virol 2016 Dec 28;90(24):11197-11207. Epub 2016 Nov 28.

Rutgers-Robert Wood Johnson Medical School, Department of Pharmacology, Piscataway, New Jersey, USA

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http://dx.doi.org/10.1128/JVI.01084-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126376PMC
December 2016

Role of Cysteines in Stabilizing the Randomized Receptor Binding Domains within Feline Leukemia Virus Envelope Proteins.

J Virol 2015 Dec 30;90(6):2971-80. Epub 2015 Dec 30.

Rutgers-Robert Wood Johnson Medical School, Department of Pharmacology, Piscataway, New Jersey, USA

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http://dx.doi.org/10.1128/JVI.02544-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810629PMC
December 2015

Structural and sequencing analysis of local target DNA recognition by MLV integrase.

Nucleic Acids Res 2015 Jun 12;43(11):5647-63. Epub 2015 May 12.

Department of Pharmacology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ 08854, USA

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http://dx.doi.org/10.1093/nar/gkv410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477651PMC
June 2015

MLV based viral-like-particles for delivery of toxic proteins and nuclear transcription factors.

Biomaterials 2014 Sep 3;35(29):8416-26. Epub 2014 Jul 3.

Department of Pharmacology, Robert Wood Johnson Medical School, Rutgers University, 675 Hoes Lane Rm 636, Piscataway, NJ, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612140068
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http://dx.doi.org/10.1016/j.biomaterials.2014.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139071PMC
September 2014

Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction.

Nucleic Acids Res 2014 May 12;42(9):5917-28. Epub 2014 Mar 12.

Department of Pharmacology, Robert Wood Johnson Medical School, Rutgers University, 675 Hoes Lane, Piscataway, NJ 08854, USA Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, 675 Hoes Lane, Piscataway, NJ 08854, USA

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http://dx.doi.org/10.1093/nar/gku175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027182PMC
May 2014

Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes.

Nucleic Acids Res 2014 Apr 11;42(8):4868-81. Epub 2014 Feb 11.

Center for Retrovirus Research and College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA, Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA and Department of Pharmacology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1093/nar/gku135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005663PMC
April 2014

Development of an enzyme-linked immunosorbent assay based on the murine leukemia virus p30 capsid protein.

J Virol Methods 2013 Nov 26;193(2):332-6. Epub 2013 Jun 26.

Department of Pharmacology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854 USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01660934130023
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http://dx.doi.org/10.1016/j.jviromet.2013.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775985PMC
November 2013

Gene delivery in a mouse xenograft of a retargeted retrovirus to a solid 143B osteosarcoma.

Virol J 2013 Jun 14;10:194. Epub 2013 Jun 14.

Department of Biochemistry, University of Medicine and Dentistry of New Jersey–Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA

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http://dx.doi.org/10.1186/1743-422X-10-194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689073PMC
June 2013

Viral DNA tethering domains complement replication-defective mutations in the p12 protein of MuLV Gag.

Proc Natl Acad Sci U S A 2013 Jun 9;110(23):9487-92. Epub 2013 May 9.

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, NJ 08854, USA.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1221736110
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http://dx.doi.org/10.1073/pnas.1221736110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677494PMC
June 2013

Library screening and receptor-directed targeting of gammaretroviral vectors.

Future Microbiol 2013 Jan;8(1):107-21

University of Medicine & Dentistry of NJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.2217/fmb.12.122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564632PMC
January 2013

Antibody-directed lentiviral gene transduction for live-cell monitoring and selection of human iPS and hES cells.

PLoS One 2012 20;7(4):e34778. Epub 2012 Apr 20.

Department of Pharmacology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034778PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334894PMC
August 2012

Comparison of the convergent receptor utilization of a retargeted feline leukemia virus envelope with a naturally-occurring porcine endogenous retrovirus A.

Virology 2012 Jun 8;427(2):118-26. Epub 2012 Mar 8.

University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Department of Biochemistry, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.virol.2012.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572736PMC
June 2012

MuLV IN mutants responsive to HDAC inhibitors enhance transcription from unintegrated retroviral DNA.

Virology 2012 May 23;426(2):188-96. Epub 2012 Feb 23.

University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00426822120008
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http://dx.doi.org/10.1016/j.virol.2012.01.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294019PMC
May 2012

Expression of an Mg2+-dependent HIV-1 RNase H construct for drug screening.

Antimicrob Agents Chemother 2011 Oct 18;55(10):4735-41. Epub 2011 Jul 18.

Programa de Virología, Instituto de Ciencias Biomédicas, Facultad de Medicina Universidad de Chile, Independencia 1027, Santiago, Chile.

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http://dx.doi.org/10.1128/AAC.00658-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186996PMC
October 2011

Antibody-directed lentiviral gene transduction in early immature hematopoietic progenitor cells.

J Gene Med 2010 Dec;12(12):945-55

Department of Biochemistry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1002/jgm.1518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057560PMC
December 2010

Fully automated high-quality NMR structure determination of small (2)H-enriched proteins.

J Struct Funct Genomics 2010 Dec 24;11(4):223-32. Epub 2010 Aug 24.

Department of Molecular Biology and Biochemistry, Center for Advanced Biotechnology and Medicine, Northeast Structural Genomics Consortium, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1007/s10969-010-9095-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970817PMC
December 2010

Efficient condensed-phase production of perdeuterated soluble and membrane proteins.

J Struct Funct Genomics 2010 Jun 24;11(2):143-154. Epub 2010 Mar 24.

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, NJ, 08854.

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http://dx.doi.org/10.1007/s10969-010-9083-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119428PMC
June 2010

Independently inducible system of gene expression for condensed single protein production (cSPP) suitable for high efficiency isotope enrichment.

J Struct Funct Genomics 2009 Sep 30;10(3):219-25. Epub 2009 Jul 30.

Department of Biochemistry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1007/s10969-009-9067-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898478PMC
September 2009

Single-round selection yields a unique retroviral envelope utilizing GPR172A as its host receptor.

Proc Natl Acad Sci U S A 2009 Apr 23;106(14):5848-53. Epub 2009 Mar 23.

University of Medicine and Dentistry of New Jersey-The Robert Wood Johnson Medical School, Department of Biochemistry, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1073/pnas.0809741106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667028PMC
April 2009

Characterization of the long-terminal repeat single-strand tail-binding site of Moloney-MuLV integrase by crosslinking.

Biol Res 2008 21;41(1):69-80. Epub 2008 Aug 21.

Programa de Virología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.

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http://dx.doi.org//S0716-97602008000100009DOI Listing
February 2009

Murine leukemia virus reverse transcriptase: structural comparison with HIV-1 reverse transcriptase.

Virus Res 2008 Jun 21;134(1-2):186-202. Epub 2008 Feb 21.

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 675 Hoes Lane, Piscataway, NJ 08854, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S016817020800005
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http://dx.doi.org/10.1016/j.virusres.2008.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443788PMC
June 2008

The MuLV 4070A G541R Env mutation decreases the stability and alters the conformation of the TM ectodomain.

Virology 2008 Feb 24;371(1):165-74. Epub 2007 Oct 24.

UMDNJ-Robert Wood Johnson Medical School, Department of Biochemistry, 675 Hoes Lane Rm. 636, Piscataway, NJ 08854, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S004268220700629
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http://dx.doi.org/10.1016/j.virol.2007.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266080PMC
February 2008

Identification of a retroviral receptor used by an envelope protein derived by peptide library screening.

Proc Natl Acad Sci U S A 2007 Jun 20;104(26):11032-7. Epub 2007 Jun 20.

Department of Biochemistry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1073/pnas.0704182104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904118PMC
June 2007

Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.

Nucleic Acids Res 2006 26;34(19):5353-60. Epub 2006 Sep 26.

Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 635 Barnhill Dr., Indianapolis, IN 46202, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkl693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636480PMC
December 2006

Revealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteins.

J Virol 2006 Oct;80(19):9497-510

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 675 Hoes Lane, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1128/JVI.00856-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617218PMC
October 2006

Selection of feline leukemia virus envelope proteins from a library by functional association with a murine leukemia virus envelope.

Virology 2006 Aug 6;351(2):340-8. Epub 2006 May 6.

Department of Biochemistry, Robert Wood Johnson Medical School/UMDNJ, 675 Hoes Lane, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.virol.2006.03.040DOI Listing
August 2006

Alteration and analyses of viral entry with library-derived peptides.

Adv Virus Res 2005 ;65:147-72

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Pisacataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1016/S0065-3527(05)65005-1DOI Listing
February 2006

Probing sequence variation in the receptor-targeting domain of feline leukemia virus envelope proteins with peptide display libraries.

J Virol 2005 Feb;79(3):1463-9

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 675 Hoes Lane, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1128/JVI.79.3.1463-1469.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544108PMC
February 2005

Expression of the C-terminus of HIV-1 reverse transcriptase p66 and p51 subunits as a single polypeptide with RNase H activity.

Protein Eng Des Sel 2004 Jul 27;17(7):581-7. Epub 2004 Aug 27.

Programa de Virología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile.

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http://dx.doi.org/10.1093/protein/gzh071DOI Listing
July 2004

Lysine directed cross-linking of viral DNA-RNA:DNA hybrid substrate to the isolated RNase H domain of HIV-1 reverse transcriptase.

Biochemistry 2004 Feb;43(5):1302-8

Programa de Virología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile.

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http://dx.doi.org/10.1021/bi035454yDOI Listing
February 2004

Differential multimerization of Moloney murine leukemia virus integrase purified under nondenaturing conditions.

Virology 2003 Nov;316(1):146-60

Department of Biochemistry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653259PMC
http://dx.doi.org/10.1016/s0042-6822(03)00559-2DOI Listing
November 2003

Molecular analysis of a recombinant M-MuLV/RaLV retrovirus.

Virology 2003 Oct;315(1):195-208

Department of Biochemistry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/s0042-6822(03)00518-xDOI Listing
October 2003

G541R within the 4070A TM protein regulates fusion in murine leukemia viruses.

J Virol 2003 Nov;77(22):12011-21

Department of Biochemistry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC254290PMC
http://dx.doi.org/10.1128/jvi.77.22.12011-12021.2003DOI Listing
November 2003

Targeting a retroviral vector in the absence of a known cell-targeting ligand.

Hum Gene Ther 2003 Nov;14(16):1557-64

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 675 Hoes Lane, Piscataway, NJ 08854-5635, USA.

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http://dx.doi.org/10.1089/104303403322495061DOI Listing
November 2003

Role of the mutation Q252R in activating membrane fusion in the murine leukemia virus surface envelope protein.

J Virol 2003 Oct;77(20):10841-9

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC224972PMC
http://dx.doi.org/10.1128/jvi.77.20.10841-10849.2003DOI Listing
October 2003

Identification of conformational and cold-sensitive mutations in the MuLV envelope protein.

Virology 2003 Aug;312(2):337-49

Department of Biochemistry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/s0042-6822(03)00244-7DOI Listing
August 2003

Functional interaction between the N- and C-terminal domains of murine leukemia virus surface envelope protein.

Virology 2003 May;310(1):130-40

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 675 Hoes Lane, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/s0042-6822(03)00111-9DOI Listing
May 2003

Inhibition of Moloney murine leukemia virus integration using polyamides targeting the long-terminal repeat sequences.

Biochemistry 2003 May;42(20):6249-58

Department of Biochemistry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway 08854, USA.

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http://dx.doi.org/10.1021/bi034177sDOI Listing
May 2003

G100R mutation within 4070A murine leukemia virus Env increases virus receptor binding, kinetics of entry, and viral transduction efficiency.

J Virol 2003 Jan;77(1):739-43

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140616PMC
http://dx.doi.org/10.1128/jvi.77.1.739-743.2003DOI Listing
January 2003

Inserting a nuclear targeting signal into a replication-competent Moloney murine leukemia virus affects viral export and is not sufficient for cell cycle-independent infection.

J Virol 2002 Aug;76(16):8475-84

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC155121PMC
http://dx.doi.org/10.1128/jvi.76.16.8475-8484.2002DOI Listing
August 2002

Altering retroviral tropism using a random-display envelope library.

Mol Ther 2002 Mar;5(3):329-35

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 675 Hoes Lane, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1006/mthe.2002.0546DOI Listing
March 2002