Monica Hollstein

Monica Hollstein

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Monica Hollstein

Monica Hollstein

Publications by authors named "Monica Hollstein"

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Nutlin-3a selects for cells harbouring TP53 mutations.

Int J Cancer 2017 02 22;140(4):877-887. Epub 2016 Nov 22.

King's College London, Analytical and Environmental Sciences Division, MRC-PHE Centre for Environment & Health, London, United Kingdom.

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http://dx.doi.org/10.1002/ijc.30504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215675PMC
February 2017

TP53 Variations in Human Cancers: New Lessons from the IARC TP53 Database and Genomics Data.

Hum Mutat 2016 09 8;37(9):865-76. Epub 2016 Jul 8.

Group of Molecular Mechanisms and Biomarkers, International Agency for Research on Cancer, Lyon Cedex 08, 69372, France.

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http://dx.doi.org/10.1002/humu.23035DOI Listing
September 2016

The genome as a record of environmental exposure.

Mutagenesis 2015 Nov 6;30(6):763-70. Epub 2015 Oct 6.

Analytical and Environmental Sciences Division, MRC-PHE Centre for Environment and Health, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK,

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http://dx.doi.org/10.1093/mutage/gev073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637815PMC
November 2015

Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization.

Nucleic Acids Res 2013 Jan 11;41(1):182-95. Epub 2012 Nov 11.

Department of Cancer Biology, Beckman Research Institute of the City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1093/nar/gks1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592471PMC
January 2013

Evidence of exposure to aristolochic acid in patients with urothelial cancer from a Balkan endemic nephropathy region of Romania.

Environ Mol Mutagen 2012 Oct 17;53(8):636-41. Epub 2012 Sep 17.

Research Group Genetic Alterations in Carcinogenesis, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/em.21732DOI Listing
October 2012

Upper urinary tract urothelial cancers: where it is A:T.

Nat Rev Cancer 2012 08;12(8):503-4

International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon, France.

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http://dx.doi.org/10.1038/nrc3311DOI Listing
August 2012

A VE-cadherin-PAR3-α-catenin complex regulates the Golgi localization and activity of cytosolic phospholipase A(2)α in endothelial cells.

Mol Biol Cell 2012 May 7;23(9):1783-96. Epub 2012 Mar 7.

Endothelial Cell Biology Unit, Institute for Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.

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http://www.molbiolcell.org/doi/10.1091/mbc.e11-08-0694
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http://dx.doi.org/10.1091/mbc.E11-08-0694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338442PMC
May 2012

Efficient introduction of specific TP53 mutations into mouse embryonic fibroblasts and embryonic stem cells.

Nat Protoc 2012 May 17;7(6):1145-60. Epub 2012 May 17.

Genetic Alterations in Carcinogenesis (C016), German Cancer Research Center (Deutsches Krebsforschungszentrum), Heidelberg, Germany.

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http://www.nature.com/articles/nprot.2012.042
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http://dx.doi.org/10.1038/nprot.2012.042DOI Listing
May 2012

Chek2ing out the p53 pathway: can Puma lead the way?

Cell Cycle 2011 May 15;10(10):1524. Epub 2011 May 15.

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http://dx.doi.org/10.4161/cc.10.10.15514DOI Listing
May 2011

Tissue-specific apoptotic effects of the p53 codon 72 polymorphism in a mouse model.

Cell Cycle 2011 May 1;10(9):1352-5. Epub 2011 May 1.

Fox Chase Cancer Center; Philadelphia PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117039PMC
http://dx.doi.org/10.4161/cc.10.9.15344DOI Listing
May 2011

Rapid derivation of genetically related mutants from embryonic cells harboring a recombinase-specific Trp53 platform.

Cell Cycle 2011 Apr 15;10(8):1261-70. Epub 2011 Apr 15.

Genetic Alterations in Carcinogenesis (C016), German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.4161/cc.10.8.15303DOI Listing
April 2011

Gene expression changes induced by the human carcinogen aristolochic acid I in renal and hepatic tissue of mice.

Int J Cancer 2011 Jan;128(1):21-32

Section of Molecular Carcinogenesis, Institute of Cancer Research, Sutton, Surrey, United Kingdom.

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http://dx.doi.org/10.1002/ijc.25324DOI Listing
January 2011

Unveiling the methylation status of CpG dinucleotides in the substituted segment of the human p53 knock-in (Hupki) mouse genome.

Mol Carcinog 2010 Dec;49(12):999-1006

Department of Cancer Biology, Beckman Research Institute of the City of Hope National Medical Center, Duarte, California, USA.

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http://dx.doi.org/10.1002/mc.20683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991417PMC
December 2010

How to become immortal: let MEFs count the ways.

Aging (Albany NY) 2010 Mar 31;2(3):160-5. Epub 2010 Mar 31.

Faculty of Medicine and Health, University of Leeds, LIGHT Laboratories, Leeds, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871244PMC
http://dx.doi.org/10.18632/aging.100129DOI Listing
March 2010

Massively regulated genes: the example of TP53.

J Pathol 2010 Jan;220(2):164-73

LIGHT Laboratories, University of Leeds, Leeds LS2 9JT, UK.

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http://dx.doi.org/10.1002/path.2637DOI Listing
January 2010

TP53 mutations in human cancers: origins, consequences, and clinical use.

Cold Spring Harb Perspect Biol 2010 Jan;2(1):a001008

Group of Molecular Carcinogenesis, International Agency for Research on Cancer, 150 Cours Albert Thomas, 69372 Lyon Cedex 08, France.

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http://cshperspectives.cshlp.org/lookup/doi/10.1101/cshpersp
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http://dx.doi.org/10.1101/cshperspect.a001008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827900PMC
January 2010

TP53 mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours.

Int J Cancer 2009 Feb;124(4):987-90

Department of Genetic Alterations in Carcinogenesis, German Cancer Research Center, Heidelberg, Germany.

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http://doi.wiley.com/10.1002/ijc.24006
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http://dx.doi.org/10.1002/ijc.24006DOI Listing
February 2009

p53 polymorphisms: cancer implications.

Nat Rev Cancer 2009 Feb;9(2):95-107

Leeds Institute of Genetics, Health and Therapeutics, LIGHT Laboratories, University of Leeds, Leeds, LS2 9JT, UK.

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http://dx.doi.org/10.1038/nrc2584DOI Listing
February 2009

The carcinogenic air pollutant 3-nitrobenzanthrone induces GC to TA transversion mutations in human p53 sequences.

Mutagenesis 2009 Jan 2;24(1):17-23. Epub 2008 Sep 2.

Division of Molecular Toxicology, Deutsches Krebsforschungszentrum (German Cancer ResearchCenter), Heidelberg, Germany.

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http://mutage.oxfordjournals.org/content/early/2008/09/02/mu
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http://www.mutage.oxfordjournals.org/cgi/doi/10.1093/mutage/
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http://dx.doi.org/10.1093/mutage/gen049DOI Listing
January 2009

Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.

Carcinogenesis 2007 Nov 13;28(11):2253-61. Epub 2007 Apr 13.

Section of Molecular Carcinogenesis, Institute of Cancer Research, Sutton, Surrey, SM2 5NG, UK.

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http://dx.doi.org/10.1093/carcin/bgm082DOI Listing
November 2007

An MVA vaccine overcomes tolerance to human p53 in mice and humans.

Cancer Immunol Immunother 2007 Aug 12;56(8):1193-205. Epub 2007 Jan 12.

Department of General and Oncologic Surgery, City of Hope National Medical Center, Duarte, CA, USA.

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http://link.springer.com/10.1007/s00262-006-0270-3
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http://dx.doi.org/10.1007/s00262-006-0270-3DOI Listing
August 2007

p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

Nat Cell Biol 2007 May 8;9(5):573-80. Epub 2007 Apr 8.

Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0322, USA.

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http://dx.doi.org/10.1038/ncb1571DOI Listing
May 2007

Mutagenesis of human p53 tumor suppressor gene sequences in embryonic fibroblasts of genetically-engineered mice.

Genet Eng (N Y) 2007 ;28:45-54

Department of Genetic Alterations in Carcinogenesis, German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

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January 2007

Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence.

Cell Cycle 2006 Dec 1;5(23):2812-9. Epub 2006 Dec 1.

Section of Molecular Biology, Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093-0322, USA.

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http://dx.doi.org/10.4161/cc.5.23.3526DOI Listing
December 2006

MEF immortalization to investigate the ins and outs of mutagenesis.

Carcinogenesis 2006 Nov 15;27(11):2141-7. Epub 2006 Jun 15.

Department of Molecular Toxicology, German Cancer Research Center (DKFZ, Deutsches Krebsforschungszentrum), Im Neuenheimer Feld 280 D69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/carcin/bgl101DOI Listing
November 2006

Quantitative analysis of plasma TP53 249Ser-mutated DNA by electrospray ionization mass spectrometry.

Cancer Epidemiol Biomarkers Prev 2005 Dec;14(12):2956-62

Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, 615 North Wolfe Street, Room E7032, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-05-0612DOI Listing
December 2005

Human p53 knock-in (hupki) mice do not differ in liver tumor response from their counterparts with murine p53.

Carcinogenesis 2005 Oct 25;26(10):1829-34. Epub 2005 May 25.

Department of Toxicology, Institute of Pharmacology and Toxicology, University of Tübingen, Wilhelmstrasse 56, 72074 Tübingen, Germany.

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http://dx.doi.org/10.1093/carcin/bgi142DOI Listing
October 2005

p53 designer genes for the modern mouse.

Cell Cycle 2004 Jun 1;3(6):738-41. Epub 2004 Jun 1.

Department of Genetic Alterations in Carcinogenesis, German Cancer Research Center, Heidelberg, Germany.

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June 2004

DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy.

Am J Kidney Dis 2004 Apr;43(4):e11-7

Division of Renal Medicine and Transplantation, Hammersmith Hospital NHS Trust, London, England UK.

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http://dx.doi.org/10.1053/j.ajkd.2003.11.024DOI Listing
April 2004

Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene.

Proc Natl Acad Sci U S A 2004 Mar 19;101(9):2963-8. Epub 2004 Feb 19.

Department of Genetic Alterations in Carcinogenesis, German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1073/pnas.0308607101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC365728PMC
March 2004

Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses.

J Biol Chem 2003 Oct 8;278(42):41028-33. Epub 2003 Aug 8.

Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093-0322, USA.

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http://dx.doi.org/10.1074/jbc.M306938200DOI Listing
October 2003

Mouse models for generating P53 gene mutation spectra.

Toxicol Lett 2002 Aug;134(1-3):31-7

Department of Genetic Alterations in Carcinogenesis, German Cancer Research Center, Dept C0700, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/s0378-4274(02)00160-1DOI Listing
August 2002

The IARC TP53 database: new online mutation analysis and recommendations to users.

Hum Mutat 2002 Jun;19(6):607-14

Molecular Carcinogenesis Group, International Agency for Research on Cancer, World Health Organization, Lyon, France.

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http://dx.doi.org/10.1002/humu.10081DOI Listing
June 2002