Mohsen Khademi

Mohsen Khademi

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Mohsen Khademi

Publications by authors named "Mohsen Khademi"

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Myelin oligodendrocyte glycoprotein revisited-sensitive detection of MOG-specific T-cells in multiple sclerosis.

J Autoimmun 2019 Aug 1;102:38-49. Epub 2019 May 1.

Therapeutic Immune Design, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine L8:02, 171 76, Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08968411193003
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http://dx.doi.org/10.1016/j.jaut.2019.04.013DOI Listing
August 2019

IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis.

J Immunol 2019 Aug 10;203(4):888-898. Epub 2019 Jul 10.

Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.4049/jimmunol.1900400DOI Listing
August 2019

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.

JAMA Neurol 2019 Jun 17. Epub 2019 Jun 17.

UCL Institute of Neurology, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1001/jamaneurol.2019.1534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580449PMC
June 2019

miR-31 regulates energy metabolism and is suppressed in T cells from patients with Sjögren's syndrome.

Eur J Immunol 2019 Feb 22;49(2):313-322. Epub 2018 Oct 22.

Unit of Rheumatology, Department of Medicine, Karolinska Institutet, Center for Molecular Medicine Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1002/eji.201747416DOI Listing
February 2019

B cell alterations during BAFF inhibition with belimumab in SLE.

EBioMedicine 2019 Feb 26;40:517-527. Epub 2018 Dec 26.

Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, 171 76 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.12.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412067PMC
February 2019

Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patients-immune-related candidate proteins affected by TNF blocking treatment.

Arthritis Res Ther 2019 Feb 15;21(1):60. Epub 2019 Feb 15.

Rheumatology Unit, Department of Medicine, Solna, Center of Molecular Medicine (CMM), Karolinska Institutet, Karolinska University Hospital, SE-17176, Stockholm, Sweden.

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https://arthritis-research.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s13075-019-1846-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377734PMC
February 2019

Identification of MS-specific serum miRNAs in an international multicenter study.

Neurol Neuroimmunol Neuroinflamm 2018 Sep 20;5(5):e491. Epub 2018 Aug 20.

Partners Multiple Sclerosis Center (K.R., B.C.H., A.P., M.A.M., R.R., P.K., T.C., H.L.W., R.G.), Brigham and Women's Hospital; Department of Neurology, Harvard Medical School (B.C.H., C.D.-C., B.I.G., T.C., H.L.W, R.G.), Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital; Biostatistics Center (B.C.H.); Massachusetts General Hospital, Boston, MA; Department of Clinical Neuroscience, Neuroimmunology Unit (M.J., F.P., T.O., M.K.), Karolinska Institute, Stockholm, Sweden; Department of Neurology (S.H., J.O.), School of Medicine, University of California, San Francisco; and Nehme and Therese Tohme Multiple Sclerosis Center (S.J.K.), Faculty of Medicine, American University of Beirut Medical Center, Lebanon.

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http://dx.doi.org/10.1212/NXI.0000000000000491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117192PMC
September 2018

Plasma neurofilament light chain levels in patients with MS switching from injectable therapies to fingolimod.

Mult Scler 2018 07 19;24(8):1046-1054. Epub 2017 Jun 19.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden/Department of Neurology, Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458517715132DOI Listing
July 2018

Monitoring disease activity in multiple sclerosis using serum neurofilament light protein.

Neurology 2017 Nov 27;89(22):2230-2237. Epub 2017 Oct 27.

From the Department of Clinical Neuroscience (L.N., M.A., C.M., J.L.) and Department of Psychiatry and Neurochemistry (H.Z., K.B.), Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg; Clinical Neurochemistry Laboratory (H.Z., K.B.), Sahlgrenska University Hospital, Mölndal, Sweden; Department of Molecular Neuroscience (H.Z.), UCL Institute of Neurology, London, UK; Department of Pharmacology and Clinical Neuroscience (P.S.), Umeå University; University Department of Clinical Neuroscience (M.K., T.O., F.P.), Neuroimmunology Unit, and Department of Clinical Sciences (A.S.), Danderyd Hospital, Karolinska Institutet, Stockholm; and Department of Neurology (M.G.), Faculty of Medicine and Health, Örebro University, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000004683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705244PMC
November 2017

Cerebrospinal fluid biomarkers as a measure of disease activity and treatment efficacy in relapsing-remitting multiple sclerosis.

J Neurochem 2017 04 29;141(2):296-304. Epub 2016 Nov 29.

Department of Clinical Neuroscience, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/jnc.13881DOI Listing
April 2017

Cerebrospinal fluid biomarkers of inflammation and degeneration as measures of fingolimod efficacy in multiple sclerosis.

Mult Scler 2017 01 11;23(1):62-71. Epub 2016 Jul 11.

Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1177/1352458516639384DOI Listing
January 2017

Autoantibody targets in vaccine-associated narcolepsy.

Autoimmunity 2016 09 20;49(6):421-433. Epub 2016 May 20.

a Affinity Proteomics, SciLifeLab, School of Biotechnology, KTH-Royal Institute of Technology , Stockholm , Sweden.

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http://dx.doi.org/10.1080/08916934.2016.1183655DOI Listing
September 2016

Absence of systemic oxidative stress and increased CSF prostaglandin F2α in progressive MS.

Neurol Neuroimmunol Neuroinflamm 2016 Aug 30;3(4):e256. Epub 2016 Jun 30.

Vascular Biology Division (M.A.L., G.J.M., R.S.), Victor Chang Cardiac Research Institute, Sydney; School of Medical Sciences (G.J.M., R.S.), University of New South Wales, Sydney, Australia; Neuroimmunology Unit (M.K., F.P., T.O.), Department of Clinical Neurosciences, Centre for Molecular Medicine, Karolinska Hospital, Stockholm, Sweden; and Department of Neurology (R.R., J.R.C., F.T.S.), Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1212/NXI.0000000000000256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929888PMC
August 2016

Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins.

Proc Natl Acad Sci U S A 2016 07 20;113(28):7864-9. Epub 2016 Jun 20.

Institute of Clinical Neuroimmunology, Ludwig-Maximilians-University, 81377 Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Ludwig-Maximilians-University, 81377 Munich, Germany

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http://www.pnas.org/content/early/2016/06/15/1522730113.full
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http://www.pnas.org/lookup/doi/10.1073/pnas.1522730113
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http://dx.doi.org/10.1073/pnas.1522730113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948369PMC
July 2016

Circulating miR-150 in CSF is a novel candidate biomarker for multiple sclerosis.

Neurol Neuroimmunol Neuroinflamm 2016 Jun 20;3(3):e219. Epub 2016 Apr 20.

Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1212/NXI.0000000000000219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841644PMC
June 2016

Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function.

Clin Immunol 2016 05 13;166-167:89-95. Epub 2016 Apr 13.

Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Sweden; Linnæus Center of Biomaterials Chemistry, Linnæus University, Kalmar, Sweden.

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http://dx.doi.org/10.1016/j.clim.2016.04.003DOI Listing
May 2016

Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination.

Neurol Neuroimmunol Neuroinflamm 2016 Feb 7;3(1):e191. Epub 2016 Jan 7.

Neuroimmunology Unit (F.A.N., M.K., S.A., T.O., F.P.), Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Institute of Infection, Immunity and Inflammation (C.E., C.L.), University of Glasgow, UK; Department of Pharmacology and Clinical Neuroscience (J.B., A.M.D., A.S.) and Neurosurgery (T.B.), Umeå University, Sweden; and Danish Multiple Sclerosis Center (J.R.C., F.S.), Department of Neurology, Rigshospitalet, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1212/NXI.0000000000000191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708925PMC
February 2016

Cerebrospinal fluid kynurenines in multiple sclerosis; relation to disease course and neurocognitive symptoms.

Brain Behav Immun 2016 Jan 17;51:47-55. Epub 2015 Jul 17.

Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbi.2015.07.016DOI Listing
January 2016

Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.

J Neuroinflammation 2015 Dec 18;12:235. Epub 2015 Dec 18.

Institute of Clinical Neuroimmunology, Biomedical Center (BMC) and University Hospital, Campus Martinsried-Grosshadern, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1186/s12974-015-0450-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683913PMC
December 2015

Hexosylceramides as intrathecal markers of worsening disability in multiple sclerosis.

Mult Scler 2015 Sep 5;21(10):1271-9. Epub 2014 Dec 5.

Department of Medical Biochemistry and Biophysics, Division of Physiological Chemistry II, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.1177/1352458514561908DOI Listing
September 2015

An evaluation of the elements of internal medicine physiopathology curriculum in general practice based on the perspectives of faculty members of Shiraz University of Medical Sciences.

J Adv Med Educ Prof 2015 Apr;3(2):62-7

Department of Curriculum Planning, Educational and Psychological Sciences Faculty, Shiraz University, Shiraz, Iran;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403566PMC
April 2015

Age-dependent effects on the treatment response of natalizumab in MS patients.

Mult Scler 2015 Jan 27;21(1):48-56. Epub 2014 May 27.

Karolinska University Hospital, Sweden.

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http://dx.doi.org/10.1177/1352458514536085DOI Listing
January 2015

Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis.

J Proteome Res 2014 Nov 1;13(11):4607-19. Epub 2014 Oct 1.

Affinity Proteomics, SciLifeLab, School of Biotechnology, KTH - Royal Institute of Technology , Stockholm 171 21, Sweden.

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http://dx.doi.org/10.1021/pr500609eDOI Listing
November 2014

Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells.

Nat Commun 2014 Oct 3;5:5056. Epub 2014 Oct 3.

Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, Zurich 8052, Switzerland.

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http://dx.doi.org/10.1038/ncomms6056DOI Listing
October 2014

Autoantibody profiling in multiple sclerosis using arrays of human protein fragments.

Mol Cell Proteomics 2013 Sep 3;12(9):2657-72. Epub 2013 Jun 3.

SciLifeLab Stockholm, School of Biotechnology, KTH-Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.1074/mcp.M112.026757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769337PMC
September 2013

Antibody-based profiling of cerebrospinal fluid within multiple sclerosis.

Proteomics 2013 Aug 25;13(15):2256-67. Epub 2013 Jun 25.

SciLifeLab Stockholm, School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.1002/pmic.201200580DOI Listing
August 2013

Serum levels of LIGHT in MS.

Mult Scler 2013 Jun 4;19(7):871-6. Epub 2012 Oct 4.

Department of Neurology, Sahlgrenska Academy at University of Gothenburg, Sweden.

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http://dx.doi.org/10.1177/1352458512463766DOI Listing
June 2013

CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis.

Mult Scler 2013 Jun 24;19(7):877-84. Epub 2012 Nov 24.

University of Copenhagen and Department of Neurology, Copenhagen University Hospital Rigshospitalet, Denmark.

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http://journals.sagepub.com/doi/10.1177/1352458512466929
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http://dx.doi.org/10.1177/1352458512466929DOI Listing
June 2013

Effects of natalizumab treatment on the cerebrospinal fluid proteome of multiple sclerosis patients.

J Proteome Res 2013 Mar 4;12(3):1101-7. Epub 2013 Feb 4.

Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/pr3012107DOI Listing
March 2013

Intravenous immunoglobulin treatment of the post-polio syndrome: sustained effects on quality of life variables and cytokine expression after one year follow up.

J Neuroinflammation 2012 Jul 9;9:167. Epub 2012 Jul 9.

Division of Rehabilitation Medicine, Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, S-19288 Stockholm, Sweden.

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http://jneuroinflammation.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/1742-2094-9-167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464723PMC
July 2012

Peripheral inflammatory disease associated with centrally activated IL-1 system in humans and mice.

Proc Natl Acad Sci U S A 2012 Jul 16;109(31):12728-33. Epub 2012 Jul 16.

Unit of Rheumatology, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.1118748109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411968PMC
July 2012

Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course.

Mult Scler 2011 Mar 6;17(3):335-43. Epub 2010 Dec 6.

Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458510389102DOI Listing
March 2011

Osteopontin concentrations are increased in cerebrospinal fluid during attacks of multiple sclerosis.

Mult Scler 2011 Jan 4;17(1):32-42. Epub 2010 Oct 4.

University of Copenhagen and Danish MS Research Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458510382247DOI Listing
January 2011

Interleukin 18 receptor 1 expression distinguishes patients with multiple sclerosis.

Mult Scler 2010 Sep 30;16(9):1056-65. Epub 2010 Mar 30.

Department of Clinical Neuroscience, Neuroimmunology Unit, Center for Molecular Medicine, Karolinska Institutet, Solna, Sweden.

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http://dx.doi.org/10.1177/1352458510364634DOI Listing
September 2010

Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers.

J Proteomics 2010 Apr 20;73(6):1117-32. Epub 2010 Jan 20.

Neuroimmunology Unit, Department of Clinical Neuroscience and Center for Molecular Medicine, Karolinska Institute at Karolinska University Hospital, Solna, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S18743919100000
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http://dx.doi.org/10.1016/j.jprot.2010.01.004DOI Listing
April 2010

Gene expression profiling in multiple sclerosis: a disease of the central nervous system, but with relapses triggered in the periphery?

Neurobiol Dis 2010 Mar 26;37(3):613-21. Epub 2009 Nov 26.

The Multiple Sclerosis Research Group, Centre for Molecular Medicine, Department of Clinical Neuroscience, Karolinska Institutet, CMM L8:00, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.nbd.2009.11.014DOI Listing
March 2010

TLR activation induces TNF-alpha production from adult neural stem/progenitor cells.

J Immunol 2009 Jun;182(11):6889-95

Department of Clinical Neurosciences, Division of Neuroimmunology, Division of Rheumatology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.4049/jimmunol.0802907DOI Listing
June 2009

Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis.

Respir Res 2009 May 29;10:42. Epub 2009 May 29.

Department of Medicine, Unit of Respiratory Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1465-9921-10-42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694180PMC
May 2009

Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis.

J Leukoc Biol 2008 Nov 21;84(5):1248-55. Epub 2008 Jul 21.

Department of Clinical Neurosciences, Neuroimmunology Unit, Karolinska University Hospital at Solna, Karolinska Institutet, Stockholm, Sweden.

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http://doi.wiley.com/10.1189/jlb.1207844
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http://dx.doi.org/10.1189/jlb.1207844DOI Listing
November 2008

Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis.

Nat Genet 2007 Sep 29;39(9):1108-13. Epub 2007 Jul 29.

Division of Neurology, Department of Clinical Neuroscience, Karolinska Institutet at Karolinska University Hospital-Huddinge, SE-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1038/ng2106DOI Listing
September 2007

Cytokine responses during chronic denervation.

J Neuroinflammation 2005 Nov 18;2:26. Epub 2005 Nov 18.

Department of Pathology, University of Turku, Kiinanmyllynkatu 10, 20520 Turku, Finland.

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http://dx.doi.org/10.1186/1742-2094-2-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310517PMC
November 2005

Expression of T cell immunoglobulin- and mucin-domain-containing molecules-1 and -3 (TIM-1 and -3) in the rat nervous and immune systems.

J Neuroimmunol 2005 Jul;164(1-2):93-104

Department of Clinical Neuroscience, Neuroimmunology Unit, CMM, L8:04, Karolinska University Hospital, Karolinska Institutet, SE 171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jneuroim.2005.04.004DOI Listing
July 2005

Prior poliomyelitis-IVIg treatment reduces proinflammatory cytokine production.

J Neuroimmunol 2004 May;150(1-2):139-44

Department of Neuroimmunology Unit, Center for Molecular Medicine, Karolinska Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jneuroim.2004.01.010DOI Listing
May 2004

In-situ detection of both inflammatory and anti-inflammatory cytokines in resting peripheral blood mononuclear cells during pregnancy.

J Reprod Immunol 2003 Feb;58(1):49-59

The Division of Obstetrics and Gynaecology, Faculty of Health Sciences, University Hospital, S-581 85 Linköping, Sweden.

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February 2003

Prior poliomyelitis-evidence of cytokine production in the central nervous system.

J Neurol Sci 2002 Dec;205(1):9-13

Department of Clinical Neuroscience, Division of Neurology, Karolinska Hospital, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/s0022-510x(02)00316-7DOI Listing
December 2002

Contralateral non-operated nerve to transected rat sciatic nerve shows increased expression of IL-1beta, TGF-beta1, TNF-alpha, and IL-10.

J Neuroimmunol 2002 Nov;132(1-2):11-7

Department of Pathology, University of Turku, Kiinanmyllynkatu 10, FIN-20520 Turku, Finland.

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http://dx.doi.org/10.1016/s0165-5728(02)00281-3DOI Listing
November 2002